100 episodes

Biopharma and medtech explained. Every week, journalists from Fierce Biotech, Fierce Medtech, and Fierce Pharma recount the latest industry trends and why they matter. We'll analyze the week's biggest business news, from mergers and marketing to drug R&D and device development. Available every Friday morning. 

The Top Line Fierce Life Sciences

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Biopharma and medtech explained. Every week, journalists from Fierce Biotech, Fierce Medtech, and Fierce Pharma recount the latest industry trends and why they matter. We'll analyze the week's biggest business news, from mergers and marketing to drug R&D and device development. Available every Friday morning. 

    Advancements in cell & gene therapy manufacturing (Part II)

    Advancements in cell & gene therapy manufacturing (Part II)

    This week’s episode of “The Top Line” is the second part of a three-part series exploring the latest advancements in cell and gene therapy manufacturing.

    In this episode, Fierce Pharma’s Fraiser Kansteiner interviews Delara Motlagh, head of cell therapy at Catalent; Becky Butler Cap, senior vice president of biotherapies at Vitalant; and Kevin Kyle, CEO of Germfree.

    The conversation covers cell collection, the critical first step in advanced therapy manufacturing. They also discuss the importance of locking in process decisions early and how to effectively scale projects from the lab to the clinic and eventually to the market. Additionally, they talk about Germfree’s recent asset acquisition from Orgenesis, which will allow the company to expand its mission of decentralized manufacturing.

    To learn more about the topics in this episode:


    Fulfilling the promise of cell & gene therapies through manufacturing (Part I)
    With new partnership, Galapagos takes decentralized CAR-T manufacturing quest nationwide
    Catalent opens cell therapy production site at Belgian 'center of excellence'
    After recent troubles, Catalent expands its biologics services platform

     
    See omnystudio.com/listener for privacy information.

    • 31 min
    Fulfilling the promise of cell & gene therapies through manufacturing (Part I)

    Fulfilling the promise of cell & gene therapies through manufacturing (Part I)

    This week’s episode of “The Top Line,” kicks off a series diving into the latest advancements in cell and gene therapy manufacturing. 

    In this episode, Fierce Pharma’s Fraiser Kansteiner sits down with Ori Biotech CEO Jason Foster and the Cell Therapy Manufacturing Center's CEO, Jason Bock. They delve into the current state of cell and gene therapy manufacturing and consider if the existing production methods can keep up with the potential of personalized medicines.

    They also dive into past hurdles in the space and highlight the varied approaches—including their own—that a new generation of cell and gene therapy manufacturing companies have been pioneering. 

    To learn more about the topics in this episode: 


    Ori Biotech taps MD Anderson, National Resilience joint venture to put its automated cell and gene therapy manufacturing tech to the test
    See omnystudio.com/listener for privacy information.

    • 29 min
    A closer look at 2023's top biopharma deals and what lies ahead

    A closer look at 2023's top biopharma deals and what lies ahead

    This week on "The Top Line," we're diving into the details of the spree of big-money biopharma deals in 2023 and examining what that means for this year.

    Fierce Pharma Senior Writer Kevin Dunleavy sits down with Cody Powers, a consultant who advises companies on business development and franchise growth strategy, to discuss the reasons behind the numerous high-value deals in 2023, which companies are primed to make major moves this year, and whether the trend of acquiring ADCs and obesity treatments will continue. 

    To learn more about the topics in this episode: 


    The top 10 biopharma M&A deals of 2023
    2024 forecast: M&A saw an uptick in 2023. Analysts expect the trend to continue
    For biopharma M&A, the best returns come from small deals: analysts
    See omnystudio.com/listener for privacy information.

    • 18 min
    A look at pharma revenue rankings

    A look at pharma revenue rankings

    Fierce Pharma publishes a yearly special report highlighting the top 20 pharmas based on their revenue. The most recent edition, published this month, ranks each pharma based on their total revenues for 2023.  

    This week on "The Top Line," Fierce Pharma Senior Editor Eric Sagonowsky and Senior Writer Kevin Dunleavy break down the numbers, highlight key trends and share some of the biggest changes at the top and bottom of the rankings year over year.  

    To learn more about the topics in this episode:  


    The top 20 pharma companies by 2023 revenue
    The top 20 pharma companies by 2022 revenue

     
    See omnystudio.com/listener for privacy information.

    • 10 min
    Winning formulas for the best biotech and drug names

    Winning formulas for the best biotech and drug names

    This week on “The Top Line,” we're joined by Fierce Biotech Senior Editor Annalee Armstrong and Fierce Pharma Marketing Senior Editor Ben Adams. We're diving into our recent spin on March Madness at Fierce.

    This time around, Fierce Biotech kicked off its inaugural Best Biotech Name tournament, while over at Fierce Pharma Marketing, we held our biannual Drug Names tournament.

    The editors discuss what makes a company or drug name tick, what to steer clear of, and how the entire competition played out. 

    To learn more about the topics in this episode: 


    #FierceMadness: AstraZeneca and Ionis cruise to victory as Wainua trounces Lilly's Mounjaro for the tournament win
    #FierceMadness: The Best Biotech Name Tournament—A champion is CROWNED
    See omnystudio.com/listener for privacy information.

    • 14 min
    [Sponsored] What does the future of specialist distribution look like?

    [Sponsored] What does the future of specialist distribution look like?

    Jeff Beck of BioCare offers his insight on patient-centric models, complex therapies, data needs, seamless product access and much more.

    • 11 min

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