Hope Lies in Dreams

Nature Biotechnology
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  • Entrepreneuriat
  • Série hebdomadaire

Stan Crooke rose from poverty to found a company that pioneered antisense drugs. After decades of struggle and years of public doubt, the company created a treatment that has saved thousands of children from the brutal disease spinal muscular atrophy. Hosted on Acast. See acast.com/privacy for more information.

Épisodes

  1. Épisode 1

    Chapter 1: an ugly place

    Stan Crooke is born ⬩ A tenuous existence ⬩ Life with his mother ⬩ The Tech Corner ⬩ Arsenal Tech High School ⬩ Nancy ⬩ Hoodlum ways ⬩ Off to Purdue Hosted on Acast. See acast.com/privacy for more information.

    Chapter 1: an ugly place

  2. Épisode 2

    Chapter 2: a winding path

    Quits Purdue ⬩ Pharmacy school ⬩ Off to Baylor ⬩ Harris Busch ⬩ Bristol Labs ⬩ SmithKline ⬩ The death of Nancy Crooke ⬩ The end of SmithKline Hosted on Acast. See acast.com/privacy for more information.

    Chapter 2: a winding path

  3. Épisode 3

    Chapter 3: San Diego restart

    Rosanne ⬩ An investor emerges ⬩ Founding Isis ⬩ The old garage ⬩ A proper space ⬩ A growing antisense scene ⬩ Starting a pipeline ⬩ Isis goes public Hosted on Acast. See acast.com/privacy for more information.

    Chapter 3: San Diego restart

  4. Épisode 4

    Chapter 4: three kinds of failure

    Stumbling out of the gate ⬩ Launch of Vitravene ⬩ Questions about antisense ⬩ The field thins ⬩ Clinical failure ⬩ The darkest days Hosted on Acast. See acast.com/privacy for more information.

    Chapter 4: three kinds of failure

  5. Épisode 5

    Chapter 5: valley of antisense

    The genomics bubble ⬩ Affinitak fails ⬩ Lynne saves the company ⬩ Hybridon pivots ⬩ New chemistries ⬩ Regulus formed ⬩ Isis as cult Hosted on Acast. See acast.com/privacy for more information.

    Chapter 5: valley of antisense

  6. Épisode 6

    Chapter 6: lone voice in the wilderness

    Rosanne saves the company ⬩ Ibis is sold ⬩ An approval ⬩ Souring on Genzyme ⬩ The end of Genta ⬩ The discovery of the SMA gene Hosted on Acast. See acast.com/privacy for more information.

    Chapter 6: lone voice in the wilderness

  7. Épisode 7

    Chapter 7: the SMA gang

    The Larsons ⬩ The skunkworks project ⬩ The most unmet need ⬩ Instant synergy ⬩ Another first for antisense ⬩ The clinic, again ⬩ The achievements of Kathie Bishop Hosted on Acast. See acast.com/privacy for more information.

    Chapter 7: the SMA gang

  8. Épisode 8

    Chapter 8: part of something big

    Ethics lessons ⬩ Biogen re-ups ⬩ The ultimate sacrifice ⬩ FDA as partner ⬩ Emma’s phase 3 ⬩ Doug Kerr’s bright idea ⬩ Isis to Ionis ⬩ Spinraza approval Hosted on Acast. See acast.com/privacy for more information.

    Chapter 8: part of something big

  9. Épisode 9

    Chapter 9: the last of his kind

    Award season ⬩ NURTURE, and Gabriel ⬩ Kyle Derkowski’s new future ⬩ The drugs of SMA ⬩ Piece of magic ⬩ Frank’s Super Bowl Hosted on Acast. See acast.com/privacy for more information.

    Chapter 9: the last of his kind

  10. Épisode 10

    Chapter 10: Dr. Crooke

    The biggest deal ⬩ In the black ⬩ End of an era ⬩ n of 1 ⬩ Small places ⬩ A life of control ⬩ The doctor will see you now Hosted on Acast. See acast.com/privacy for more information.

    Chapter 10: Dr. Crooke

  11. 01/09/2021

    Hope Lies in Dreams trailer

    Trailer for upcoming 10-part series, Hope Lies in Dreams. Hosted on Acast. See acast.com/privacy for more information.

    Hope Lies in Dreams trailer

Bande-annonce

À propos

Stan Crooke rose from poverty to found a company that pioneered antisense drugs. After decades of struggle and years of public doubt, the company created a treatment that has saved thousands of children from the brutal disease spinal muscular atrophy. Hosted on Acast. See acast.com/privacy for more information.

Informations

  • Création
    Nature Biotechnology
  • Années d’activité
    2021
  • Épisodes
    11
  • Classification
    Tous publics
  • Site web de l’émission
    Hope Lies in Dreams