3 Minute 3Rs

The NC3Rs, the North American 3Rs Collaborative, and Lab Animal
  • 5.0 (1)
  • SCIENCE
3 Minute 3Rs

3 Minute 3Rs is your monthly recap of efforts to replace, reduce, and refine the use of animals in research, brought to you by the NC3Rs, the North American 3Rs Collaborative, and Lab Animal. Hosted on Acast. See acast.com/privacy for more information.

  1. 16/02/2023

    Assessing enrichment, consolidating animal research guidance and understanding mouse aggression

    February 2023   The papers behind the pod: Hobbiesiefken U et al. (2023). Rating enrichment items by female group-housed laboratory mice in multiple binary choice tests using an RFID-based tracking system. PloS one 18(1): e0278709. doi: 10.1371/journal.pone.0278709Petkov C et al. (2022). Unified ethical principles and an animal research ‘Helsinki’ declaration as foundations for international collaboration. Current Research in Neurobiology 3:100060. doi: 10.1016/j.crneur.2022.100060Weber E et al. (2023). Aggression in Group-Housed Male Mice: A Systematic Review. Animals 13(1):143. doi: 10.3390/ani13010143 It’s the third Thursday of February and you’re listening to the final episode of 3 minute 3Rs, recapping the latest efforts to replace, reduce and refine the use of animals in research. Follow this link for the full transcript: https://www.nc3rs.org.uk/3-minute-3rs-podcast-february-2023-transcript Hosted on Acast. See acast.com/privacy for more information.

    4 min

  2. 19/01/2023

    Replacing animal-derived reagents, simulating in utero microinjections and clicker training for mouse gait assessment

    January 2023   The papers behind the pod: Cassotta M et al. (2022). A worldwide survey on the use of animal-derived materials and reagents in scientific experimentation. Engineering in Life Sciences 22(9):561-604. doi: 10.1002/elsc.202100167  Nuber M et al. (2022). Development of a 3D simulator for training the mouse in utero electroporation. PLOS One 17(12): e0279004. doi: 10.1371/journal.pone.0279004Dickmann J et al. (2022). Clicker Training Mice for Improved Compliance in the Catwalk Test. Animals 12(24): 3545. doi: 10.3390/ani12243545 Happy New Year to all 3 Minute 3Rs listeners. It’s 2023, and we’re back with three more papers highlighting efforts to replace, reduce and refine the use of animals in research. Follow this link for the full transcript: https://www.nc3rs.org.uk/3-minute-3rs-podcast-january-2023-transcript   Hosted on Acast. See acast.com/privacy for more information.

    5 min

  3. 15/12/2022

    Kidney organoid vascularisation, implementing masking and quantitatively assessing experiment severity

    December 2022 The papers behind the pod: Menéndez ABC et al. (2022). Creating a kidney organoid-vasculature interaction model using a novel organ-on-chip system. Scientific Reports 12:20699. doi: 10.1038/s41598-022-24945-5Karp N et al. (2022). A qualitative study of the barriers to using blinding in in vivo experiments and suggestions for improvement. PLOS Biology 20(11): e3001873. doi: 10.1371/journal.pbio.3001873Talbot S et al. (2022). RELSA—A multidimensional procedure for the comparative assessment of well-being and the quantitative determination of severity in experimental procedures. Frontiers in Veterinary Science 9:937711. doi: 10.3389/fvets.2022.937711  It’s the third Thursday of December, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce and refine the use of animals in research. To round off 2022 we are highlighting a paper for each R. Follow this link for the full transcript: https://www.nc3rs.org.uk/3-minute-3rs-podcast-december-2022-transcript Hosted on Acast. See acast.com/privacy for more information.

    4 min

  4. 17/11/2022

    Assessing pain, living systematic reviews and inducing focal hypoxia in human neurons

    November 2022 The papers behind the pod: Aulehner K et al. (2022). Grimace scale, burrowing, and nest building for the assessment of post-surgical pain in mice and rats—A systematic review. Frontiers in Veterinary Science 9:930005. doi: 10.3389/fvets.2022.930005Hair K et al. (2022). ‘Living’ evidence frameworks for in vivo animal research: towards translational evidence-based medicine. BMJ Evidence-Based Medicine 2022;27:A17. doi: 10.1136/ebm-2022-EBMLive.31 Wong J et al. (2022). Electrochemically induced in vitro focal hypoxia in human neurons. Frontiers in Cell and Developmental Biology 10:968341. doi: 10.3389/fcell.2022.968341 It’s the third Thursday of November, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce and refine the use of animals in research. Follow this link for the full transcript: https://www.nc3rs.org.uk/3-minute-3rs-podcast-november-2022-transcript Hosted on Acast. See acast.com/privacy for more information.

    4 min

  5. 20/10/2022

    Statistical planning, human cell cultures for toxoplasma and preventing boredom in laboratory rodents

    October 2022 The papers behind the pod: Piper, SK et al. (2022). Statistical review of animal trials—A guideline. Biometrical Journal https://doi.org/10.1002/bimj.202200061 Gargaté MJ et al. (2022). Parallel Propagation of Toxoplasma gondii In Vivo, In Vitro and in Alternate Model: Towards Less Dependence on the Mice Model. Pathogens https://doi.org/10.3390/pathogens11091038 Mieske P et al. et al. (2022). Bored at home?—A systematic review on the effect of environmental enrichment on the welfare of laboratory rats and mice. Frontiers in Veterinary Science https://doi.org/10.3389/fvets.2022.899219 It’s the third Thursday of October, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce and refine the use of animals in research. This month we have a paper on each R. Follow this link for the full transcript: https://nc3rs.org.uk/3-minute-3rs-podcast-october-2022-transcript Hosted on Acast. See acast.com/privacy for more information.

    4 min

  6. 15/09/2022

    Larger species refinement special: improving the welfare of rabbits, non-human primates and sheep

    September 2022 The papers behind the pod: Pinho RH et al. (2022). Validation of the rabbit pain behaviour scale (RPBS) to assess acute postoperative pain in rabbits (Oryctolagus cuniculus). PLoS ONE 17(5): e0268973. https://doi.org/10.1371/journal.pone.0268973 Stull C, Heagerty A and Coleman K (2022). Video Conference Technology as a Tool for Pair Introduction in Rhesus Macaques. Animals 12(14): e1783. https://doi.org/10.3390/ani12141783  Zentrich E et al. (2022). Postoperative Severity Assessment in Sheep. European Surgical Research, in press. https://doi.org/10.1159/000526058 It’s the third Thursday of September, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce, and refine the use of animals in research. This month we’re focusing on refinements for working with three different non-rodent species. Follow this link for the full transcript: https://nc3rs.org.uk/3-minute-3rs-podcast-september-2022-transcript Hosted on Acast. See acast.com/privacy for more information.

    5 min

  7. 18/08/2022

    Better behavioural research, imaging with microbots and how housing density affects mouse microbiomes

    August 2022 The papers behind the pod: Arjmand S et al. (2022). Tips and traps for behavioural animal experimentation. Acta Neuropsychiatrica, in press. https://doi.org/10.1017/neu.2022.4Wrede P et al. (2022). Real-time 3D optoacoustic tracking of cell-sized magnetic microrobots circulating in the mouse brain vasculature. Science Advances 8(19). https://doi.org/10.1126/sciadv.abm9132 Russell A et al. (2022). Reduced housing density improves statistical power of murine gut microbiota studies. Cell Reports 39(6): e110783. https://doi.org/10.1016/j.celrep.2022.110783 It’s the third Thursday of August, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce, and refine the use of animals in research. Follow this link for the full transcript: https://nc3rs.org.uk/3-minute-3rs-podcast-august-2022-transcript Hosted on Acast. See acast.com/privacy for more information.

    4 min

  8. 21/07/2022

    3Rs Prize: A benchtop organ-on-a-chip fabrication method and an ex vivo model of focal demyelination

    July 2022 The papers behind the pod: Ferreira DA et al. (2021). Alternative to Soft Lithography for the Fabrication of Organ-on-a-Chip Elastomeric-Based Devices and Microactuators. Advanced Science 8:2003273.  https://doi.org/10.1002/advs.202003273Eigel D et al. (2019). Cryogel scaffolds for regionally constrained delivery of lysophosphatidylcholine to central nervous system slice cultures: A model of focal demyelination for multiple sclerosis research. Acta Biomaterialia 97:216.  https://doi.org/10.1016/j.actbio.2019.08.030 It’s the third Thursday of July, and you’re listening to 3 Minute 3Rs, your monthly recap of efforts to replace, reduce, and refine the use of animals in research. This month, we’ve got a special double feature highlighting the publications commended in the International 3Rs Prize, awarded by the NC3Rs and sponsored by GSK. Follow this link for the full transcript: https://nc3rs.org.uk/3-minute-3rs-podcast-july-2022-transcript Hosted on Acast. See acast.com/privacy for more information.

    4 min
See All (64)

    About

    3 Minute 3Rs is your monthly recap of efforts to replace, reduce, and refine the use of animals in research, brought to you by the NC3Rs, the North American 3Rs Collaborative, and Lab Animal. Hosted on Acast. See acast.com/privacy for more information.

    Information

    • Creator
      The NC3Rs, the North American 3Rs Collaborative, and Lab Animal
    • Years Active
      2017 - 2023
    • Episodes
      64
    • Rating
      Clean
    • Copyright
      © All rights reserved
    • Show Website
      3 Minute 3Rs

    Content Restricted

    This episode cannot be played on the web in your country or region.

    To listen to explicit episodes, sign in.

    Stay up to date with this show

    Sign in or sign up to follow shows, save episodes and get the latest updates.
    Select a country or region

    Africa, Middle East, and India

    Asia Pacific

    Europe

    Latin America and the Caribbean

    The United States and Canada