Hump Day Hormones

Dr. Jill Jennings & Kortney Spann, APRN

This is a podcast about all things hormones! Dr. Jill Jennings and Kortney Spann, APRN are so excited to share their knowledge and expertise about menopause, perimenopause, and hormone imbalances.

  1. 2 hr ago

    Meet the Newest Member of the Hump Day Hormones Team: Amy Wilson

    This week we're introducing the newest nurse practitioner at The Women's Clinic, Amy Wilson, APRN, and giving you the chance to get to know the person behind the provider. With years of experience in women's health and specialized training in urogynecology, Amy shares why she dedicated her career to helping women feel heard, understood, and empowered through every stage of life. In this episode, we discuss: • Amy's journey into women's health and what led her to our practice • Why so many women feel dismissed and how compassionate care can change that • Common hormone myths and what every woman should know about hormone therapy • What urogynecology is and when women should seek care for pelvic floor concerns • The symptoms women often dismiss as "just aging" that deserve a closer look • Amy's advice for women who are ready to take control of their health Whether you're navigating menopause, hormone concerns, pelvic floor symptoms, or simply looking for a provider who truly listens, this episode is a chance to meet someone who's passionate about providing personalized, evidence based care. We're thrilled to welcome Amy to the team and can't wait for you to get to know her. Share this episode with someone who's looking for a women's health provider who truly listens. Women's Health Provider | Hormone Therapy | Menopause Care | Urogynecology | Pelvic Floor Health | Hormone Optimization | Women's Wellness | Menopause Specialist #HumpDayHormones #AmyWilson #WomensHealth #HormoneHealth #Menopause #Urogynecology #PelvicFloorHealth #HormoneTherapy #HealthyAging #WomensWellness

    Meet the Newest Member of the Hump  Day Hormones Team: Amy Wilson
  2. 22 Jul

    Should We Check Estradiol Levels? Why Your Number Might Matter More Than You Think

    "Should your estradiol level be checked while you're on hormone therapy?" "Or do your symptoms tell us everything we need to know?" It's one of the biggest debates in menopause medicine. Some providers say blood levels don't matter. Others want to see your estradiol above a certain number. So... who's right? In this episode, we unpack what the research actually says and explain why the answer depends on what you're trying to accomplish. While symptoms remain the best guide for relieving hot flashes and night sweats, optimizing long term health may be a different conversation. In this episode, we break down: • Why routine estradiol testing isn't recommended for every woman on hormone therapy • What estradiol levels may tell us about bone health and osteoporosis prevention • How estrogen supports cardiovascular health, healthy blood vessels, and cholesterol • The connection between estradiol, insulin resistance, and metabolic health • What we know, and don't yet know, about estrogen and brain health after menopause • Why treating symptoms and optimizing long term health aren't always the same goal • How to think about estradiol numbers without chasing a "perfect" lab value The biggest takeaway? We don't treat lab numbers, we treat women. Hormone therapy should always be individualized, using both symptoms and the best available evidence to support long term health. Share this episode with someone navigating menopause or a healthcare provider who wants to stay up to date on the evolving science of hormone therapy. #HumpDayHormones #Menopause #Estradiol #HormoneReplacementTherapy #HormoneHealth #BoneHealth #HeartHealth #Women'sHealth #MenopauseEducation #HealthyAging

    Should We Check Estradiol Levels? Why Your Number Might Matter More Than You Think
  3. 15 Jul

    GLP-1s & Breast Cancer: What the New Research Really Says

    A new Penn Medicine study is making headlines after researchers found that women taking GLP-1 medications had about 30% lower odds of being diagnosed with breast cancer compared to similar women who were not taking these medications. So what does that actually mean? In this episode, we separate the headlines from the science and explain why researchers are excited, while also discussing what we still don't know. In this episode, we break down: • What the new Penn Medicine breast cancer study actually found • Why a 30% lower risk does not mean 30 out of 100 women avoided breast cancer • How obesity, insulin resistance, inflammation, and estrogen influence breast cancer risk • The biologic reasons GLP-1 medications may help reduce cancer risk • The important limitations of this research and why it does not prove cause and effect • What these findings could mean for women with obesity, insulin resistance, or a family history of breast cancer The most exciting part of this research isn't that we suddenly have a new breast cancer prevention drug. It's that improving metabolic health may impact far more than the number on the scale. As always, we'll discuss what the evidence supports today, what questions remain unanswered, and where the research is headed next. Share this with someone who's been seeing the headlines and wondering what they really mean. #HumpDayHormones #GLP1 #BreastCancerResearch #Semaglutide #Tirzepatide #WomensHealth #HormoneHealth #MetabolicHealth #BreastCancerAwareness #MedicalResearch

    GLP-1s & Breast Cancer: What the New Research Really Says
  4. 1 Jul

    PCOS Is Getting a New Name - And It’s About Time - PMOS

    After nearly 100 years, one of the most common hormone disorders affecting women has officially been renamed. Following a 14 year international effort involving more than 22,000 patients, researchers, and medical experts, Polycystic Ovary Syndrome (PCOS) is now being called Polyendocrine Metabolic Ovarian Syndrome (PMOS). Why does that matter? Because the new name finally reflects what science has been telling us for years, this is a whole body hormonal and metabolic condition, not simply an ovarian disorder. In this episode, we break down: • Why PCOS was officially renamed PMOS and what prompted the historic change • What the new name tells us about hormones, insulin resistance, and metabolism • Why up to 70% of women with PMOS remain undiagnosed • The four different types of PMOS patients we commonly see in clinic • The long term health risks that extend far beyond fertility and irregular periods • Why treatment needs to focus on both hormone balance and metabolic health One of the biggest takeaways from this episode is that you probably know someone living with PMOS, whether they realize it or not. The condition affects up to 1 in 7 women of reproductive age, making it one of the most common endocrine disorders in women. Understanding the new name isn't just about changing terminology. It's about changing the conversation, improving diagnosis, reducing stigma, and helping women receive the care they deserve. Share this with a friend because chances are... you have a friend with PMOS. #HumpDayHormones #PMOS #PCOS #HormoneHealth #InsulinResistance #WomensHealth #MetabolicHealth #EndocrineHealth #HormoneEducation #WomensWellness

    PCOS Is Getting a New Name - And It’s About Time - PMOS
  5. 24 Jun

    GLP-1 Summer School: The Questions We’re Getting Asked All Summer Long

    This week we're heading back to school, GLP-1 Summer School, to answer the questions we're getting asked every single day in clinic. A few years ago, hardly anyone had heard of medications like Ozempic, Wegovy, Mounjaro, and Zepbound. Now they're everywhere. Some people think they're a miracle. Others think they're dangerous. Most women are simply trying to sort through the noise and understand what is actually true. In this episode, we break down: • How GLP-1 medications actually work in the body • What realistic weight loss looks like with semaglutide and tirzepatide • Why these medications are about much more than weight loss • Whether you'll gain weight back after stopping and how to transition off successfully • The truth about muscle loss, hair loss, and "Ozempic face" • How GLP-1 therapy and hormone replacement therapy may work together • What patients should know about compounded medications • Why retatrutide is generating so much excitement for the future of obesity medicine We also discuss one of the biggest misconceptions surrounding GLP-1 therapy: the idea that the medication is the entire treatment plan. The medication may open the door, but long term success still depends on nutrition, muscle preservation, sleep, stress management, hormone health, and sustainable habits. This conversation is designed to help you understand the science, separate fact from fiction, and make sense of one of the fastest moving areas in medicine today. Share this with the friend who keeps texting you GLP-1 questions. #HumpDayHormones #GLP1 #Semaglutide #Tirzepatide #Ozempic #Wegovy #Zepbound #Mounjaro #MetabolicHealth #WeightLossMedicine #HormoneHealth #WomensHealth

    GLP-1 Summer School: The Questions We’re Getting Asked All Summer Long
  6. 10 Jun

    Why Your Skin Changes During Perimenopause with Special Guest Susan Campbell

    “Why does my skin suddenly feel dry, thin, sensitive, and impossible to manage?” “Is it aging... or is it my hormones?” This week we're joined by Susan Campbell, founder and CEO of Phosis Skincare, an award winning skincare brand created specifically for perimenopausal and menopausal women. Susan's innovative approach to skincare earned national recognition when Phosis was selected by Oprah Daily's Menopause O Awards, making her one of the leading voices in this rapidly growing space. Many women notice changes in their skin long before they recognize other symptoms of perimenopause. Dryness, loss of firmness, increased sensitivity, and stubborn changes in skin texture are often some of the earliest signs that hormones are shifting. In this episode, we break down: • What actually happens to skin during perimenopause and menopause • How declining estrogen impacts collagen, hydration, elasticity, and skin barrier function • Why skin often becomes noticeably drier after 40 • The surprising connection between hormones and skin health • How much collagen women lose during and after menopause • Which skincare ingredients become more important during midlife • Common misconceptions women have about aging skin • Where skincare fits alongside hormones, supplements, and aesthetic treatments • Why caring for menopausal skin requires a different approach Susan also shares her incredible entrepreneurial journey, including: • How she identified a major gap in the skincare industry • The inspiration behind creating Phosis • What it took to build a skincare company from the ground up • The story behind being selected for Oprah Daily's Menopause O Awards • What happened when Oprah's team discovered Phosis • A behind the scenes look at a potential Shark Tank opportunity • Advice for anyone sitting on a business idea they've been afraid to pursue This conversation is about more than skincare. It's about understanding that the changes women experience during perimenopause and menopause are real, biologically driven, and deserving of solutions designed specifically for them. Because healthy aging isn't about chasing youth. It's about supporting your body through every stage of life. Share this with the woman who's wondering why her skincare routine suddenly stopped working.

    Why Your Skin Changes During Perimenopause with Special Guest Susan Campbell
  7. 3 Jun

    Progesterone Problems with Speical Guest Meg Green

    “Your progesterone is low.” “But is low progesterone actually the problem... or is it a symptom of something deeper?” This week we're joined by returning guest Meg Green, Registered Dietitian and Integrative & Functional Nutrition Certified Practitioner, for a deep dive into one of the most talked about hormones in women's health: progesterone. From anxiety and insomnia to weight gain and PMS, progesterone gets blamed for almost everything online. But what does progesterone actually do, what causes it to decline, and how much of the conversation are we getting wrong? In this episode, we break down: • What progesterone actually does beyond fertility and pregnancy • How progesterone impacts sleep, mood, anxiety, and brain function • The relationship between progesterone and estrogen balance • Why many women labeled with "estrogen dominance" may actually be dealing with ovulation issues or declining progesterone • Common symptoms associated with low progesterone and what may be causing them • Whether low progesterone truly causes weight gain • Why some women notice weight changes after starting progesterone therapy • The connection between stress, cortisol, inflammation, and progesterone production • How sleep deprivation, under eating, over exercising, and blood sugar swings can affect ovulation • What low progesterone looks like in younger women, postpartum women, and women in perimenopause • The role vitamin D and nutrition may play in hormone health • Why symptoms matter just as much as lab values Meg also helps us sort through some of the biggest myths surrounding progesterone, including whether stress can completely shut down progesterone production, whether regular cycles guarantee healthy progesterone levels, and whether every woman with anxiety in perimenopause needs progesterone. This conversation is a reminder that progesterone may be part of the story, but it is rarely the whole story. Because understanding why hormones change is often more important than focusing on a single number. Share this with the woman who's been told low progesterone is the answer to everything. #HumpDayHormones #Progesterone #HormoneHealth #WomensHealth #Perimenopause #FunctionalNutrition #MegGreen #HormoneBalance #WomensWellness

    Progesterone Problems with Speical Guest Meg Green
  8. 20 May

    Cortisol Chaos... Is It Sabotaging The Rest Of Your Hormones? With Special Guest Christa Jackson

    Are you exhausted but wired, waking at 3am, and wondering why your body feels out of sync?” “What if it is not just stress, but a full hormone and cortisol conversation your body is trying to have with you?” We are joined by Christa Jackson, APRN at Beyond Wellness, a clinician deeply rooted in personalized, root cause hormone care and formerly with Cornerstone OB GYN alongside Dr Kay Chandler. In this conversation, we dive into what she is seeing every day in women who feel overwhelmed, dismissed, and physically off balance. This episode unpacks what we are calling cortisol chaos, the intersection of chronic stress, hormone shifts, sleep disruption, and the realities of perimenopause that so many women are navigating at once. In this episode, we break down: • Why so many women feel anxious, fatigued, and unlike themselves during this stage of life • What cortisol actually does in the body and why it is essential, not the enemy • How chronic stress, sleep disruption, and blood sugar swings create a feedback loop • Why estrogen plays a major role in stress resilience and emotional stability • What changes in perimenopause that makes stress feel harder to recover from • How cortisol interacts with thyroid function and energy regulation • What clinicians are actually seeing in labs, symptoms, and real patient stories • Lifestyle and hormonal strategies that support recovery instead of burnout We also talk through what it looks like in real clinical practice when women feel terrible but are told everything looks normal, and how a different approach to hormones, sleep, and nervous system health can change everything. This conversation is about more than cortisol. It is about understanding what your body is adapting to, and why it is not failing you, it is responding. Share this with the woman who feels like her body is stuck in overdrive.

    Cortisol Chaos... Is It Sabotaging The Rest Of Your Hormones? With Special Guest Christa Jackson

About

This is a podcast about all things hormones! Dr. Jill Jennings and Kortney Spann, APRN are so excited to share their knowledge and expertise about menopause, perimenopause, and hormone imbalances.

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