pharmaphorum Podcast

pharmaphorum
pharmaphorum Podcast

pharmaphorum is one of the leading global channels for insight into the pharma and healthcare industry – and is essentially a group of passionate people who like asking excellent questions. Our podcasts offer a chance to pose some of these questions to the keenest minds in our industry to look at the big issues and opportunities facing pharma, biotech and healthcare today. With interviews and contributions from a host of industry experts and insiders, the pharmaphorum podcast is a must-listen for those who want insight into the future of health and medicine.

  1. For the continuum of mental health we need a whole system, holistic 'healthspan'

    31 MAR

    For the continuum of mental health we need a whole system, holistic 'healthspan'

    If we don’t address the mental health of young people, that mental health challenge will advance into the adult population of tomorrow. What can be done to address the issue, though? At Anthropy 2025: Rebooting Britain, web editor Nicole Raleigh sat down with Dr Sebastian Vaughn, CEO of Phytome Life Sciences, for an en plein air and explorative conversation around the topic, live onsite at The Eden Project in Cornwall, following the Adelphi sponsored panel, ‘Revolutionary Thinking for Mental Health’, also with: Charlotte Baldwin, Mental Health UK; Dr Lauren Waterman, NHS; Sarah Hughes, MIND; and Dr Sri Kalidindi CBE, klip Global Ltd; and Lloyd Morgan, Adelphi Group, as moderator. Action in the real world resultant from discussions like those held at Anthropy is what is, of course, critical. We are all agents of change. Mental health is not a binary issue, says Vaughn, but rather a continuum of a life-long management process. However, the healthcare system alone is not the only point of delivery, and community-based solutions need to be put in place, too. Indeed, it is this system shift to collaborative efforts that will be key in changing the recent high tide of mental health diagnoses, including training teachers and even parents in the skills necessary to provide support for young people with mental health issues. Also exploring the increase in diagnosis, the lessening of stigma attached to mental health, and potential reasons there – Vaughn posits that ‘healthspan’, as opposed to ‘healthcare’, should be considered. Arguing against associating addressing mental health with putting people back to work and mere consideration of productivity amelioration, instead we should be asking what helps us thrive as human beings, says Vaughn. We need, simply, to live better, and live well – such strategies currently being implemented in communities such as those in Manchester. But, of course, young people themselves need to be offered a place at the table to make the changes they need for their own mental health; systemic change of the culture around mental health. And novel, holistic approaches that can be scaled – such as those being explored at Phytome – could be part of the necessary shift. You can listen to episode 170a of the pharmaphorum podcast in the player below, download the episode to your computer, or find it - and subscribe to the rest of the series - in iTunes, Spotify, Amazon Music, Podbean, and pretty much wherever you get your other podcasts!

    36 min
  2. IRA updates and making sense of the chaos in Washington, with Alice Valder Curran

    20 MAR

    IRA updates and making sense of the chaos in Washington, with Alice Valder Curran

    Last year, Alice Valder Curran, a partner at Hogan Lovells and a healthcare policy expert in Washington, D.C. joined host Jonah Comstock on the pharmaphorum podcast to talk about the intended and unintended consequences of the drug pricing negotiation provisions in the Inflation Reduction Act. On today’s episode, Curran joins us once again for an update on the IRA, looking at the second batch of drugs announced in January, recent messaging from the Centers for Medicare and Medicaid Services and what it might communicate about their thinking, and more analysis of IRA’s consequences, including a recent study on the impact of the IRA on early stage investment. She also talks about the possibility that, because of perverse incentives for pharmacy benefit managers, patient access to medications negotiated under the IRA could actually get worse. And she looks ahead to the third round of negotiations, which will see Part D drugs, including Keytruda, become eligible. While the IRA was the main focus of discussion, Curran and Comstock discuss a lot more about the current chaotic environment in DC, including the potential impact of layoffs on the functioning of agencies like CMS and FDA, the outlook for the possibility of IRA reform under the Trump administration, and the recent dispatch from Secretary of Health and Human Services Robert F. Kennedy indicating a change in policy around notice and comment rulemaking.  Things are happening fast in the United States government and the ripples could have big effects for the pharma industry. Tune in for the low-down from an expert insider.

    38 min
  3. Patient-focused manufacturing models for personalised therapies

    28 FEB

    Patient-focused manufacturing models for personalised therapies

    Unique, patient-focused manufacturing models are needed to scale up innovative cell therapies for cancer and one company, CTMC, is challenging the status quo to achieve this and get them to patients. In a new pharmaphorum podcast, web editor Nicole Raleigh speaks with Jason Bock, co-founder and CEO of CTMC, a first-of-its-kind cell therapy engine aiming to advance novel scientific breakthroughs into medicines developed rapidly and robustly to - ultimately - end cancer. Taking learnings from the monoclonal antibody field to come up with a fit-for-purpose solution, Bock discusses his work in the joint venture between the MD Anderson Cancer Center and biopharmaceutical manufacturer Resilience – combining industrial manufacturing and development capabilities with the work of an academic medical centre. CTMC’s is a “patient adjacent” manufacturing model – crucial when it comes to developing personalised therapies (especially when dealing with living cells), and Bock explains how patient-centric approaches streamline manufacturing processes, improve efficacy, and allow for that personalised treatment approach, particularly when the supply chain is local. You can listen to episode 168a of the pharmaphorum podcast in the player below, download the episode to your computer, or find it - and subscribe to the rest of the series - in iTunes, Spotify, Amazon Music, Podbean, and pretty much wherever you get your other podcasts!

    23 min

Ratings & Reviews

4.2
out of 5
5 Ratings

About

pharmaphorum is one of the leading global channels for insight into the pharma and healthcare industry – and is essentially a group of passionate people who like asking excellent questions. Our podcasts offer a chance to pose some of these questions to the keenest minds in our industry to look at the big issues and opportunities facing pharma, biotech and healthcare today. With interviews and contributions from a host of industry experts and insiders, the pharmaphorum podcast is a must-listen for those who want insight into the future of health and medicine.

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