In this episode of On The Line, host Matt Gurney is joined by two guests for conversations about politics, technology, and trust. This episode of On The Line is brought to you by BioCanRX, a federally funded, not-for-profit Canadian research network that specializes in bringing Canadian cancer immunotherapy research from the lab all the way to patients in clinical trials in Canada. Can science help your immune system detect and destroy cancer? Immunotherapy is about assisting your immune system in identifying unhealthy cells –– especially cancer –– that have found a way to evade detection. One way researchers are doing this is through something called CAR T. They draw your blood, isolate one type of your immune cells –– T-Cells –– and use a virus to inject genetic instructions that cause them to grow new receptors designed specifically to bind with your particular cancer. When those cells are re-infused into your body, they hopefully will be able to find and destroy your cancer. The results are promising. In one of the 16 trials BioCanRx funds based on Canadian technology, CLIC-01, the median number of months remaining for patients with late-stage leukemia and lymphoma tripled. For some, the response was even bigger: they went from being out of options to cancer free, and have stayed that way for several years. Many questions remain — and we're working on answering them. You'll hear more over the summer. For now, go to BioCanRX.com to learn more. First up is PJ Fournier of 338Canada for a look at the latest political numbers. They discuss the good news for Mark Carney, the bad news for Pierre Poilievre, and why the Liberal numbers may not be quite as strong as they first appear. The conversation then turns to Quebec, where the next provincial election is shaping up to be one of the strangest contests either man can remember. Fournier struggles to find a historical comparison. They also discuss softening support for separation in Quebec, how that compares with developments in Alberta, and a point Matt makes that PJ suspects may not be especially popular with Quebec nationalists — even if he doesn’t disagree with it. Then Matt is joined by David Shipley of Beauceron Security for a discussion about artificial intelligence, social media, and the growing gap between technological change and political institutions. How much of the current AI boom is real, and how much is hype fuelled by companies racing toward public offerings? Shipley argues that Canadians deserve greater transparency around the Tumbler Ridge case, while Matt notes that he can’t even get straightforward answers about transit delays, leaving him less than optimistic about the prospects for accountability. This episode is also brought to you by the Forest Products Association of Canada. A stronger forest industry starts with predictability. Mill modernization, bioenergy, mass timber, and advanced biomaterials all depend on reliable access to usable Canadian wood fibre, workable timelines, and clear rules. Provinces lead forest management, and the federal role should be coordinated, complementary, and focused on results. Every unnecessary delay makes it harder to keep jobs and attract investment. For a sector rooted in communities, regulatory efficiency is economic policy. Learn more at FPAC.ca. The conversation also examines how major social media platforms are being exploited for fraud and manipulation, an issue Shipley has been testifying about. The core problem, he argues, is that the internet moves at the speed of light while politicians move at the speed of Parliament. That mismatch is creating vulnerabilities that are only getting worse. The episode closes with a warning to Albertans heading into a possible referendum campaign: Shipley isn’t telling anyone how to vote, but he is urging people to be extremely careful about what they believe online. Foreign interference efforts are already arriving, and they’re unlikely to get less sophisticated from here. This episode is also brought to you by Cameco. In nuclear energy, timelines and costs matter. Incomplete designs carry real risk of delays and cost overruns. That’s why the AP1000 reactor is the right choice for Canada: it is already operating today and ready now to deliver the power we need, with 100 percent Canadian ownership and strong participation from Canadian suppliers. If we are serious about building Canada and powering it on time and on budget, the choice is clear. The AP1000 reactor is the only option that delivers. To learn more, visit ap1000.cameco.com. Check out our main page at ReadTheLine.ca and be sure to like and subscribe. We’ll be back on Friday with another episode of The Line Podcast. #OnTheLine #CanadaPolitics #338Canada #PJFournier #MarkCarney #PierrePoilievre #QuebecPolitics #AlbertaPolitics #ArtificialIntelligence #CyberSecurity #DavidShipley #ForeignInterference #MattGurney