Core Memory

Ashlee Vance

Core Memory is a podcast about science and technology hosted by best-selling author and filmmaker Ashlee Vance. Vance has spent the past two decades chronicling advances in science and tech for publications like The Economist, The New York Times and Bloomberg Businessweek. Along with the stories, he's written best-selling books like Elon Musk’s biography, made an Emmy-nominated tech TV show watched by millions and produced films for HBO and Netflix. The goal has always been to bring the tales of complex technology and compelling people to the public and give them a path into exceptional and unusual worlds they would not normally have a chance to experience. www.corememory.com

  1. The Space Race Is So Back — EP 76 Ashlee Vance And Kylie Robison

    5 hr ago

    The Space Race Is So Back — EP 76 Ashlee Vance And Kylie Robison

    The theme for this week’s episode is tick, tick, boom. America is running out of time to catch up with China on manufacturing, and we’re physically incapable of spending an hour together without bringing it up. Release the glorious machines please!! We also go behind the scenes on Kylie’s reporting on motors and actuators — the unglamorous parts that sit in every joint of a humanoid robot, account for roughly 60% of what that robot costs to build, and come almost entirely from China. Her piece profiles the two startups trying to change that. Plus a new proposed bill out of Congress that would kick Unitree’s robot doggies to the curb. Then the rockets send Ashlee off on his space tangents. Jeff Bezos’ Blue Origin had an expensive mishap recently when an explosion took out the rocket, its launch pad, and possibly America’s dreams of beating China back to the moon. Ashlee walks through why a pad explosion can be a near-death moment for a rocket company, and why SpaceX — now flying roughly every two days while everyone else is grounded or behind — increasingly just wins by default. Plus the new Starfall capsule, SpaceX’s move into making medicine and maybe chips in orbit, and the wild logic behind a $1.77 trillion IPO. We also got into the media drama consuming our X timeline: the firing of Scott Pelley from 60 Minutes. Ashlee tweeted an opinion, the trolls came for him hard, and he pleads his case here. We’re a little biased since, well, we’re off building this whole new-media thing ourselves. Will there still be a ticking clock and a man in a suit raking in views twenty years from now? Tune in for what we think, and leave your hot take in the comments. The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends. (Ed. Kylie - Don’t think I forgot to make you a playlist. “Lazy Eye” and “New Slang” were key to my college experience. I first crushed on Rivers Cuomo thanks to “Perfect Situation.” Listen to it here, and don’t forget to leave a comment to win tickets to their tour). OUR SPONSORS SendCutSend Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you. Brex The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster. Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did. We run on Brex and so should you. Learn more about Brex right here. Timestamps * 00:00:00 – Intro * 00:02:05 – The American Actuator Crisis * 00:06:51 – WestMag vs. Atlas Motion Systems * 00:14:21 – Uncle Sam Pays Attention * 00:16:47 – Chinese Robot Ban * 00:21:16 – A Robot in Every Home * 00:24:29 – Are You AGI-pilled Yet? * 00:27:23 – Shoutout to Micayla Sortland * 00:31:01 – Blue Origin’s Explosive Launch * 00:42:52 – Low Earth Orbit Drugs * 00:49:42 – The Two-Trillion-Dollar Elon Bet * 00:57:07 – Founders Fund’s Viral “Mafia” Game Night * 01:01:23 – Ashlee Braves His Notifications * 01:06:12 – Legacy Media vs. The World This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

    1hr 23min
  2. Can You Reverse Decades of Drinking Damage? Perhaps. - EP 75 Jacob Kimmel Is Back

    2 Jun

    Can You Reverse Decades of Drinking Damage? Perhaps. - EP 75 Jacob Kimmel Is Back

    Jacob Kimmel returns to the show. And he might have cured the hangover and liver disease. NBD. Kimmel is the co-founder and president of NewLimit and one of the deepest thinkers in the longevity field. His company has been working to reverse the aging process in the body and has seen some stunning results with a new therapy that undoes liver damage in mice. We’re talking old mice that shrug off the effects of too much booze as if they were teenagers and that exhibit recoveries from long-term alcohol abuse. The results have been good enough to help NewLimit raise another $435 million from the likes of Founders Fund and Thrive Capital. They’re also good enough to have NewLimit kick off a human trial of the therapy next year. And I’ll drink to that. We discuss all of this on the podcast and then go much deeper on the longevity field, bio-tech and the collision of AI and biology. The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends. OUR SPONSORS SendCutSend Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you. Brex The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster. Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did. We run on Brex and so should you. Learn more about Brex right here. Timestamps 0:0) Intro3:50 What Is Epigenetic Reprogramming?7:16 Growing a Whole Animal From One Old Cell13:06 Meet Ambrosia, the AI Hunting for Youth22:44 $435 Million and the Race to Human Trials29:26 The Drunk Mice That Skip the Hangover36:48 Inside the First Human Trial43:14 Will There Ever Be a Hangover Pen?49:39 Beyond the Liver: The Delivery Problem1:03:27 Answering the Skeptics1:12:42 Will OpenAI Become a Drug Company?1:23:53 The Health Story Bigger Than AI?1:35:00 How Far Behind Is the US vs China?1:53:10 Can We Build Computers From Neurons? This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

    2 hr
  3. The Startup Trying to Save Us From AI Bioweapons- EP 74 Hannu Rajaniemi

    27 May

    The Startup Trying to Save Us From AI Bioweapons- EP 74 Hannu Rajaniemi

    Our guest this week is the renowned science fiction author Hannu Rajaniemi. And he has come to terrify and then perhaps comfort you. Rajaniemi made an immediate name for himself in literary circles with his debut novel The Quantum Thief. He’s since written a string of novels that explore the directions technology might take in the future, and his work always stands out for its creativity and imagination. These days, Rajaniemi is putting those skills to very practical use at Red Queen Bio. The company appeared near the end of last year with a focus on AI biosecurity. Red Queen’s main objective is to try and outthink and outflank bad actors and/or AI systems run amok that might unleash bioweapons onto the world. As such, Red Queen must concoct all sorts of dark scenarios and then come up with ways to undercut and defeat them. Rajaniemi has a background in mathematics, physics and bio-tech and possesses one of those fast-twitch minds that makes the rest of us envious. We talked about his life and career and, obviously, the wild reality we now inhabit. The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends. OUR SPONSORS SendCutSend Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you. Brex The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster. Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did. We run on Brex and so should you. Learn more about Brex right here. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

    1hr 48min
  4. 22 May

    Schmidt Out of Luck — EP 73 Ashlee Vance And Kylie Robison

    We are back with another episode of Ashlee and Kylie gossiping about the latest in Silicon Valley. First, a re-cap of our Alexandr Wang interview — his first real sit-down in eleven months — and what it actually revealed about Meta’s AI play. Wang seemed nervous hashing out the strategy in the studio, and we both keep circling the same puzzle: Meta has endless compute and top talent in Nat Friedman and Daniel Gross, so why does the model still feel underwhelming? We get into Eric Schmidt getting booed off a commencement stage at the University of Arizona, which becomes a longer conversation about the generational fury aimed at AI. Everyone Kylie’s age seems to hate it, but is it due to misinformation or legitimate anger about jobs and data centers? Ashlee admits he’s more confused by this moment than anything he’s covered in tech: the predicted Wall Street collapse hasn’t come, the models keep getting better, and the valuations still make no sense. Then, the news that broke minutes before we hit record: OpenAI won the Musk lawsuit on statute-of-limitations grounds. We dig into whether OpenAI’s shift from open-source nonprofit to for-profit was an original sin or just the only way to pay for the compute. Also, Ashlee’s texts with Sam Altman being part of discovery?! In more Musk news, Bloomberg reported that Musk’s xAI stiffed staff on the $420 they were promised for feeding their tax returns into Grok. One host would decidedly not trust a chatbot with their financials, and the other already has. We also get into the strange new bedfellows: SpaceX selling compute to Anthropic, a company Musk has long been philosophically against. We even take you behind the scenes at Core Memory — so study up and watch our latest videos on Phantom Neuro and Starfront Observatories. Consider this your homework on mind-controlled arms and galaxy photography. Essay due on our desk by morning. Don’t forget you could win tickets to the Weezer tour by leaving an amazing review for our podcast wherever you listen. The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends. OUR SPONSORS SendCutSend Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you. Brex The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster. Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did. We run on Brex and so should you. Learn more about Brex right here. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

    55 min
  5. The Freshman Who Took Down Stanford's President And Its Perfect Image - EP 72 Theo Baker

    20 May

    The Freshman Who Took Down Stanford's President And Its Perfect Image - EP 72 Theo Baker

    As a freshman, Theo Baker signed up to write for The Stanford Daily on a lark. He thought it might be a fun way to spend some time when he wasn’t busy studying and coding. But then, he turned out to be quite good at reporting and tips started coming his way. One of these tips included information suggesting that there were inconsistencies and perhaps massive errors in past scientific papers tied to Stanford’s then-president Marc Tessier-Lavigne. Despite warnings to stay away from the story, Baker pursued it and produced a string of pieces that did, in fact, show a long history of shoddy research publications linked to Tessier-Lavigne. The mighty Stanford president, who had been a towering force in the scientific community, resigned by the end of Baker’s freshman year. Baker has now written a book about his experience and joined the podcast to discuss it. How to Rule the World: An Education in Power at Stanford University is three things: a rollicking account of Baker’s takedown of Tessier-Lavigne, an indictment of the start-up-obsessed culture Stanford has fostered, and something of a memoir, describing what it’s like to endure one of the more unusual freshman years any student will ever have. The bulk of the book focuses on Stanford and what it has become, which is a meat market of young, brilliant minds being wooed by the venture capitalists seeking to acquire their talents. There are investors paying students tens of thousands of dollars for connections to other students and inviting the kids to their mansions and sex parties. All very wholesome stuff. The book is fantastic. Baker is a rare talent. We had a wonderful conversation. You will enjoy it. The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends. OUR SPONSORS SendCutSend Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you. Brex The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster. Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did. We run on Brex and so should you. Learn more about Brex right here. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

    1hr 27min
  6. Meta's AI Chief On AI Beef, New Models And Life With Zuck - EP 71 Alex Wang

    13 May

    Meta's AI Chief On AI Beef, New Models And Life With Zuck - EP 71 Alex Wang

    Last June, Meta pried Alex Wang away from Scale AI, the company he co-founded and ran, in a deal valued at $14 billion. Zuck could feel Meta fading in the AI race and decided that Wang was the rescue plan. He would work full-time at Meta, assemble a super team and hopefully make the company more competitive against the likes of OpenAI, Anthropic and Alphabet. Wang has basically been in hiding ever since. He moved from San Francisco to the South Bay to be closer to Meta’s headquarters and has been working non-stop. Last month, the world saw the first fruits of the revitalized AI effort in the form of Meta’s new Muse Spark model. And now Wang is speaking for the first time about the model, Meta’s grand AI ambitions and all the happenings over the last year in an exclusive interview here on the Core Memory podcast. Wang arrived at our studio sporting a mullet and a powerful whitetail deer camouflage shirt. He was in good spirits and tried his best to convince us that Meta can catch up to its rivals. We hit on his personal beef with Sam Altman, Zuck delivering soup to AI recruits, the incredible pay packages Meta has been handing out, the vast amount of work Meta still has to do and the Meta AI hierarchy that includes all-stars like Nat Friedman, Daniel Gross and Shengjia Zhao, who seems to have blocked me on X for reasons I know nothing about. The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you like the show, please leave a review and tell your friends. Enjoy! Do you make stuff? Do you need metal parts fast and believe in truth and justice? Then head on over to SendCutSend where you’ll get a 15 percent discount thanks to Core Memory on whatever you’re trying to build. We believe in you. The Core Memory podcast is also sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster. Did we go to Texas, find a telescope ranch and then obtain an entire nebula in Brex’s honor? Oh yes, we did. We run on Brex and so should you. Learn more about Brex right here. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

    1hr 23min
  7. Everything You Need To Know About The Nuclear Energy Boom - EP 70 James Krellenstein

    6 May

    Everything You Need To Know About The Nuclear Energy Boom - EP 70 James Krellenstein

    We’re in the midst of a new nuclear energy boom. Start-ups – both fusion and fission – abound, and the U.S. government has cleared the way to build again. Meanwhile, China is racing ahead with nuclear plans that dwarf those of the rest of the world combined. As with any boom cycle, there is a lot of hype and a lot to understand if you want to get a handle on what’s real and what’s not. And so, we brought James Krellenstein onto the podcast. He’s the co-founder and CEO of Alva Energy and he’s sort of frightening in how much he knows about the nuclear industry. Like, really. You’ll see. This episode runs long because we wanted to use it as a chance to go through the past few decades of history and really explain why the U.S. nuclear industry slowed and how the U.S. might fix the situation. We also wanted to explain how all these new technologies work and, of course, explore where China is heading. Krellenstein is something of a contrarian and thinks many of the U.S. nuclear start-ups are misguided in their approach. He’s also incredible to listen to. You will enjoy this one. I think it’s one of the best episodes we’ve ever done. The Core Memory podcast is on all major platforms and on our YouTube channel over here. If you enjoy the show, please leave a review and tell your friends. This podcast is sponsored by Brex, the intelligent finance platform built to help companies spend smarter and move faster. We run on Brex and so should you. Learn more about Brex right here. We’ve also brought on a new sponsor. Welcome, SendCutSend!! They are an American manufacturing powerhouse and will help you make your metal parts with speed and skill. Core Memory subscribers can get a 15 percent discount on their next parts right here. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.corememory.com/subscribe

    2h 35m

About

Core Memory is a podcast about science and technology hosted by best-selling author and filmmaker Ashlee Vance. Vance has spent the past two decades chronicling advances in science and tech for publications like The Economist, The New York Times and Bloomberg Businessweek. Along with the stories, he's written best-selling books like Elon Musk’s biography, made an Emmy-nominated tech TV show watched by millions and produced films for HBO and Netflix. The goal has always been to bring the tales of complex technology and compelling people to the public and give them a path into exceptional and unusual worlds they would not normally have a chance to experience. www.corememory.com

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