Sequoia Capital

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頻道 • 3 個節目

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5日前

OpenAI's Greg Brockman: Why Human Attention Is the New Bottleneck

Greg Brockman, co-founder and president of OpenAI, joins Sequoia partner Alfred Lin at AI Ascent 2026 for a conversation that spans the full OpenAI stack. He explains why the company will never have enough compute, why he believes we're 80% of the way to AGI, and why the agentic coding tools that wrote 20% of your code last December are now writing 80% of it. Also: why human attention is becoming the scarcest resource in AI-augmented work, and what it might be like to one day run an organization of 100,000 agents.

5日前

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28 分鐘
6日前

Andrej Karpathy: From Vibe Coding to Agentic Engineering

Andrej Karpathy (co-founder of OpenAI, former head of AI at Tesla, and now founder of Eureka Labs) talks with Sequoia partner Stephanie Zhan at AI Ascent 2026 about what's changed in the year since he coined "vibe coding." He explains why he's never felt more behind as a programmer, why agentic engineering is the more serious discipline taking shape on top of vibe coding, and why we should think of LLMs not as animals but as ghosts: jagged, statistical, summoned entities that require a new kind of taste and judgment to direct. He also touches on Software 3.0, the limits of verifiability, and why you can outsource your thinking but never your understanding.

6日前

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30 分鐘
04/12/2025

Palo Alto Networks ft Nir Zuk & Nikesh Arora - The Grudge That Transformed Cybersecurity

In the early 2000s, the cybersecurity industry was dominated by incumbents focused on high margins, not innovation. Nir Zuk tells the story of how, frustrated by this stagnant culture, he set out on his own with a radical idea: the Next-Generation Firewall. His vision was to unify dozens of security functions into a single, intelligent platform delivered via cloud—an approach everyone thought was crazy. Palo Alto Networks started as a disruptive startup with Nir sporting a "Check Point Killer" vanity license plate, and grew to dominate cybersecurity. We explore the crucible moments that defined its path: the controversial decision to insist on being a new kind of "firewall" vs. a “firewall helper,” the challenge of scaling a hyper-growth company, and the critical pivot from building everything in-house to current CEO Nikesh Arora’s aggressive acquisition strategy that remade the company for the cloud era. Nir, Nikesh, and the core leadership team offer a masterclass in product conviction, strategic transformation, and the courage to disrupt yourself before the market does it for you. Featuring: Nir Zuk, Nikesh Arora, Lee Klarich, Rajiv Batra, Mark McLaughlin, Jim Goetz, Asheem Chandra Hosted by: Roelof Botha, Sequoia Capital

04/12/2025

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47 分鐘
1日前

Anthropic's Boris Cherny: Coding's Printing Press Moment

Boris Cherny, creator of Claude Code at Anthropic, joins Sequoia partner Lauren Reeder at AI Ascent 2026 to talk about where coding goes from here. He explains why he hasn't written a line of code in 2026, why he now ships dozens of PRs a day from his phone, and why he believes coding is effectively solved — at least for the code he writes. Also: why loops are the future, why he thinks Claude Code itself may be 100 lines of code a year from now, and why the invention of the printing press is the right analogy for what's about to happen to software.

1日前

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25 分鐘
1日前

Waymo's Dmitri Dolgov: 20 Million Rides and the Road to Full Autonomy

Dmitri Dolgov, co-CEO of Waymo, joins Sequoia partner Konstantine Buhler at AI Ascent 2026 to talk about the 20-year arc from the DARPA Grand Challenge to fully autonomous service in eleven cities and counting. He explains how Waymo persisted through every AV hype cycle by treating safety as the non-negotiable foundation, why exponential scaling is finally here (10 of Waymo's 20 million autonomous rides have happened in the last seven months), and how the Waymo Foundation Model — a multimodal world action model that powers the driver, the simulator, and the critic — actually works under the hood. Also: why Waymo is now 13x safer than human drivers, and the moment a Waymo detected a pedestrian behind a city bus by reading the LiDAR returns of their feet.

1日前

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27 分鐘
6日前

Demis Hassabis on Building DeepMind, AlphaFold, and the Final Stretch to AGI

Demis Hassabis, co-founder and CEO of Google DeepMind and 2024 Nobel laureate in chemistry for AlphaFold, joins Sequoia partner Konstantine Buhler at AI Ascent 2026 for a wide-ranging conversation about the path to AGI and what comes after. He explains why he believes AGI is achievable by 2030, why drug discovery could collapse from ten years to days, and why we should think of information, not matter or energy, as the most fundamental substance in the universe. Also: what Einstein would tell us about the limits of today's models, and why the next year or two will be critical for humanity.

6日前

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27 分鐘
4月2日

Jack Dorsey: Every Company Can Now Be a Mini-AGI

Jack Dorsey (Block CEO) and Roelof Botha (Sequoia partner and Block board member) join to discuss a bold claim they wrote about recently: the traditional corporate hierarchy isn't just inefficient — it's obsolete. Jack made one of the toughest calls in recent business history: cutting 40% of his workforce and rebuilding the company from the ground up around what he calls an AI "intelligence layer." We get into how that conversation went down, the math they used to land on a number, and why he's convinced that acting from a position of strength beats reacting from one of weakness. Jack breaks down his vision for simplifying into just three roles, and what it means to replace a pyramid org chart with a circle — AI at the center, and people at the edge. Roelof, who helped think through the restructuring, shares his perspective on how AI-native startups are building differently, and what CEO qualities are timeless. I've eliminated org charts before. I know how hard this is. But Jack is doing something I never had the tools to pull off. If you're a founder wondering whether your hierarchy is working for you or against you, this one will make you uncomfortable in the best way.

4月2日

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1 小時 4 分鐘
4月14日

From SEO to Agent-Led Growth: Profound’s James Cadwallader

James Cadwallader, co-founder and CEO of Profound, makes the case that we are living through the biggest platform shift in marketing history. The front door of the internet hasn't changed, but the visitor walking through it has. Where consumers once clicked blue links, AI agents now crawl the web on their behalf, synthesizing answers and steering purchase decisions at scale. James explains why Gemini, ChatGPT, and Claude all recommend brands differently, why mapping AI visibility onto traditional SEO is the wrong instinct, and why the real imperative is to equip a superintelligent agent with original insight it couldn't find anywhere else. He also digs into the dead internet theory – the possibility that human browsing could largely cease within three years – how AI advertising may become the most effective form the world has ever seen, and why agent-led marketing isn't just automation of the old work, but an entirely new capability. Hosted by Sonya Huang, Sequoia Capital

4月14日

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31 分鐘
4月16日

What Founders Can Learn About Excellence From MIT President Sally Kornbluth

Sally Kornbluth is president of MIT and one of the best crisis leaders I've come across. Within a year of starting the job, she got summoned – not invited – to testify before Congress alongside the presidents of Harvard and UPenn. You know how that went. The others didn’t make it. Sally did, and she came out stronger. We spend a lot of time on sustaining meritocracy, which I think is one of the hardest things for any scaling CEO to pull off. Sally has a line I can't shake: if you take a lick of the lollipop of mediocrity, you suck forever. That's how MIT has operated for 150+ years. We get into how you actually hold the bar as you scale, why most founders drop it without realizing it, and what to do once you've dropped it. We also get into the crisis playbook – staying calm on the outside when you're screaming inside, why explaining is losing, and why having a board that's truly behind you is the most underrated variable in whether you survive. The board backing her was the pivotal moment, full stop. Other things we cover: what managing PhD students taught her about leading without being overbearing, the 5:1 praise ratio and why it doesn't cost you anything, how she told the federal government "no thanks" on their higher ed compact, and what AI actually means for education, including why writing is still thinking.

4月16日

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44 分鐘
2月3日

What’s the Future of Vertical SaaS in an AGI World? Jamie Cuffe, CEO of Pace

Jamie Cuffe is solving one of AI's hardest problems: getting conservative, regulated industries to trust autonomous agents with mission-critical work. At Pace, he's building AI that replaces traditional BPOs in insurance, handling everything from email triage to claims processing with 50-75% cost savings. Drawing on his experience at Retool, Jamie emphasizes the importance of "closing the distance" with customers through forward-deployed engineering and being "the rock" that clients can rely on. He shares how focusing on top-tier insurance carriers and maintaining exceptionally high standards is enabling Pace to capture a meaningful share of the $400 billion BPO market while building a durable business model - at AI-native velocity. Hosted by Lauren Reeder and Pat Grady, Sequoia Capital

2月3日

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52 分鐘

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