LONGEVITY with Nathalie Niddam Nathalie Niddam

Did you know that your gallbladder plays a vital role in maintaining overall health and longevity? In today’s bonus episode, I dive deep into the importance of TUDCA, a bile acid that supports not only gallbladder and liver function but also has far-reaching effects on digestion, fat-soluble vitamin absorption, gut health, and even brain function.
 
Taking care of your gallbladder and liver is essential for optimal health. I share my personal experience with gallstones and how incorporating TUDCA into my supplement regimen has made a significant difference in my well-being, including improved sleep quality and reduced inflammation.
 
To learn more about the benefits of TUDCA, the crucial role of the gallbladder, and how to incorporate this supplement into your routine, be sure to tune in. 
 
Thank you to our sponsors for making this episode possible:
LVLUP: Use code NAT10 to save 10% off at https://lvluphealth.com/
 
Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0
Instagram: https://www.instagram.com/nathalieniddam/
Website: NatNiddam.com
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance
 
What I discuss:
03:03 The Importance of TUDCA for Bile Flow and Digestion
07:50 Supporting Liver Health and Mitochondria with Tudka
10:44 TUDCA’s Potential Benefits for Brain Health and Neurodegenerative Diseases
14:02 Personal Experience with TUDCA and Gallbladder Issues
25:01 The Importance of Sourcing High-Quality Supplements



Key Takeaways:
TUDCA is a bile acid that improves bile flow, digestion of fats, and absorption of fat-soluble vitamins.
It supports liver health, helps with the breakdown of cellular waste in mitochondria, and has beneficial effects on the microbiome.
TUDCA may have potential benefits for brain health and neurodegenerative diseases.
It can help with gallbladder issues, food tolerance, and lower liver enzymes.
Combining TUDCA with other supplements, such as liver support and oxbile, can provide comprehensive liver and gallbladder support.
It is important to source high-quality supplements from reputable companies.
 

Could the health of your skin be one of the best predictors of chronic disease risk and mortality? 
 
In today’s episode of The Longevity Podcast, Kiran Krishnan and I discuss how aging and dysfunction of skin, driven by changes in the skin microbiome, may actually precede and contribute to unhealthiness in the body, rather than simply reflecting it. Maintaining your skin's barrier function by supporting a balanced, diverse skin microbiome could be a crucial factor for health and longevity.
 
Our conversation delves into the science of the skin microbiome, how modern products and lifestyles impact it, and practical strategies to keep your skin's ecosystem thriving. Don't miss this episode, which may forever change how you think about skincare and healthy aging.
 
Kiran Krishnan is the chief microbiologist at Just Thrive with 20 years of experience in the dietary supplement and nutrition market. He comes from a strict research background, having spent several years with hands-on R&D in the fields of molecular medicine and microbiology at the University of Iowa.
 
To Try SIV Serum for yourself go to SIVCARE.com and use code NAT10 to save on your purchase
 
Thank you to our sponsors for making this episode possible:
Fatty15: Visit http://fatty15.com/NAT and use promo code NAT to save.
Vitali: Visit https://www.vitaliskincare.com/discount/Nathalie20 and use code Nathalie20 to save on your order.
Berkeley Life: Consumers may register and place an order using my code NIDDBL for 10% off at berkeleylife.com
Young Goose: www.Younggoose.com. Use code NAT10 on first order and 5NAT for all future orders
 
Find more from Kiran Krishnan: 
Instagram: @kiranbiome
 
Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 
Instagram: https://www.instagram.com/nathalieniddam/ 
Website: www.NatNiddam.com   
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 



What We Discuss: 
03:05 GLP-1 Agonists and Gut Microbiome
19:27 The Barrier Function of the Skin and Aging
24:01 The Acid Mantle and pH of the Skin
28:12 The Role of Ceramides in Skin Health
39:07 Reinforcing and Supporting the Skin Microbiome
41:03 Quorum Sensing and Biome Balancing Serum
43:23 Application of Biome Balancing Serum
46:28 Improving Skin Health and Appearance
49:50 Maintaining Skin Health in a Toxic Environment
50:14 Ideal pH for Skincare Products
 
Key Takeaways
The skin plays a crucial role in longevity and health span, acting as a dynamic barrier and protecting against toxins and pathogens.
Maintaining the pH of the skin and the ceramide layer is essential for skin health and preventing age-related skin issues.
Phytoceramides, obtained from plants, can help support the health of the skin and may be beneficial in skincare products. The majority of skin care products are not good for the skin microbiome, but it is not feasible to eliminate their use completely.
 

Do you get enough sunlight? Most of us don't get adequate exposure to the sun's beneficial rays. 
 
In today’s episode, I sit down with Gerardo Gutierrez (Guti), the creator of an innovative UV light device that mimics the healing properties of natural sunlight by delivering red, infrared, and UVB light frequencies in a specially formulated sequence. Guti shares insights from his research into how these different light bands impact our biology and overall well-being. Strategic sunlight exposure provides a wide range of health benefits - from boosting vitamin D, serotonin, and testosterone levels to improving conditions like eczema and psoriasis. 
 
Overall, this conversation provides a nuanced understanding of light and its impact on our health. We discuss the benefits of light therapy and the MitoLux device. 
 
A few years ago, Guti went through depression, low vitamin D levels, and other health issues. Instead of staying on medication long-term, he discovered the therapeutic benefits of sunlight exposure. Taking daily sunbaths allowed him to get off antidepressants and testosterone replacement therapy within just 3 months. Now Guti is on a mission to educate others about getting their "daily dose of sunshine" through strategic light exposure, whether from the sun itself or his therapeutic UV light invention.
 
To learn more about Mitolux go to Mitolux.com and use code Longevity10
 
Thank you to our sponsors for making this episode possible:
UBLOCKOUT: Visit: UBLOCKOUT.com and use code NAT10 to save on your Ultimate Blackout Shade order.
Troscriptions: Use code NATPODCAST at https://troscriptions.com/
 
Find more from Mitolux: 
Website: https://mitolux.com/ 
Instagram: @mitoluxusa
 
Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 
Instagram: https://www.instagram.com/nathalieniddam/ 
Website: www.NatNiddam.com   
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 



What We Discuss: 
03:04 Different Types of Light and Their Effects
09:59 Strategic Sun Exposure and the Role of UVA and UVB
14:56 The Benefits of Infrared Light and UV Exposure
29:08 The Importance of Getting the Full Spectrum of Sunlight
31:52 The Benefits of Vitamin D and Sunlight Exposure
40:03 Sunlight and Testosterone Production
46:05 The Power of Red Light Therapy
50:32 Harnessing the Power of UVB Light
59:14 The Impact of Light Therapy on Autoimmune and Skin Conditions
01:03:29 The Contradictory Research on Sun Exposure and Skin Cancer
01:08:01 Choosing Non-Toxic Sunscreen for Sun Protection



Key Takeaways:
 
Strategic sun exposure, particularly in the morning and evening, can provide numerous health benefits.
Infrared light has protective effects and can neutralize free radicals created by UV exposure.
UVA rays are linked to skin aging and certain types of cancer, while UVB rays can cause sunburn but also trigger the production of vitamin D and serotonin.
The MitoLux device emits UVB light and is designed to provide the optimal dose for health benefits.

Have you ever sifted through a mountain of health advice only to feel more lost than when you started? 
 
That's where Dr. Elizabeth Yurth comes in—guiding us through aging research with her knowledgeable insights. In today’s episode, we discuss anti-aging medicine, the pitfalls of research bias, and the gender discrepancies that muddy the waters of scientific studies. 
With a nod to John Ioannidis' work, we talk about the need for validating scientific claims. When theory meets practice, the truth can be surprising. We share firsthand experiences from clinical work, revealing how animal studies fare once they reach the human testing ground. 
 
Overall, we explore the heart of longevity, where social connections and stress-free living are crucial. 
 
Dr. Elizabeth Yurth is the Co-Founder and Chief Medical Officer of Boulder Longevity Institute, where she has been providing Tomorrow’s Medicine Today to her clients since 2006. Dr. Yurth has completed over 500 hours of Continuing Medical Education (CME) training in the areas of Longevity, Epigenetics, Nutrition, Bioidentical Hormone Replacement Therapy, Regenerative Peptide Treatments, and Regenerative Orthopedic Procedures. 



Thank you to our sponsors for making this episode possible:
Quicksilver: Visit quicksilverscientific.com/nat and use code Nat for 10% off your first purchase of PushCatch® Liver Detox.
BiOptimizers: For Sleep Breakthrough use code bionat at checkout to save on your order at bioptimizers.com/bionat
 
Find more from Dr. Elizabeth Yurth: 
Website: https://boulderlongevity.com/ 
Instagram: @boulderlongevityinstitute
Youtube: https://www.youtube.com/@boulderlongevityinstitutel5018 
 
Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 
Instagram: https://www.instagram.com/nathalieniddam/ 
Website: www.NatNiddam.com   
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 



What We Discuss: 
(00:02) Navigating Aging Research and Recommendations
(07:22) Clinical Testing Ground for Longevity Drugs
(20:05) Benefits and Risks of Antioxidants
(31:42) Cycling Supplements and Aging Measurements
(35:47) Reevaluating Biological Aging and Longevity
(45:03) Low-Dose Naltrexone for Repurposed Medication
(54:56) Drug Repurposing for Various Health Conditions
(01:00:33) Weight Loss Drugs and Their Effects
(01:11:24) Cellular Health and Longevity Discussion



Key Takeaways:
Research findings should be critically evaluated, considering factors such as study design, reproducibility, and applicability to humans.
LDN can be effective in reducing cramps and arthritis symptoms by deactivating microglial cells.
Amlexanox is an underutilized drug with anti-allergic and anti-inflammatory properties.
Tessafensin, a triple uptake inhibitor, may aid in weight loss and improve cellular function.
 

When you think of creatine, what comes to mind? If you're like most people, you probably associate it with building muscle and enhancing athletic performance. But did you know that creatine has benefits that go far beyond the gym?
 
In today's podcast episode, I dive into the fascinating world of creatine and discuss its incredible potential for supporting brain health, bone density, and even protecting your DNA from damage. That's right – creatine isn't just for athletes anymore!
 
To get the full scoop on how this simple compound can help you optimize your health and potentially slow down the aging process, I encourage you to tune in. In just 30 minutes, you'll gain a wealth of knowledge about creatine and how to incorporate it into your daily routine for maximum benefits.



Thank you to our sponsors for making this episode possible:
LVLUP: Use code NAT10 to save 10% off at https://lvluphealth.com/
 
Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0
Instagram: https://www.instagram.com/nathalieniddam/
Website: NatNiddam.com
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance
 
What I discuss:
2:24 How to supplement with creatine 
4:47 How creatine works in the mitochondria  
7:11 Creatine's benefits for muscle, including satellite cell activation and heat tolerance 
9:34 Creatine's benefits for bone health and remodeling  
11:59 Creatine's neuroprotective effects and cognitive benefits, especially for older adults  
14:25 Creatine's potential benefits for depression, diabetes, and cardiac insufficiency  
16:24 Creatine's role in protecting mitochondrial DNA from damage  
21:00 Concerns about creatine supplementation, including kidney health, hair loss, and cancer 
25:43 Recommendations for creatine supplements and how to incorporate them into your routine  



Key Takeaways:
Creatine has wide-ranging benefits beyond athletic performance, including muscle, bone, brain, DNA protection, diabetes, heart health, and skin.
Supplementation guidelines for creatine include dosing, timing, and potential concerns for kidney health, hair loss, and cancer.
Creatine may have positive effects on various health conditions, but individuals should consult with their healthcare provider before starting supplementation.

Are you tired of yo-yo dieting and struggling to achieve lasting weight loss? Have you heard about the buzz surrounding GLP-1 agonist medications like semaglutide and tirzepatide but aren't sure how to effectively incorporate them into your journey? 
 
In today’s episode, Dr. Gus Vickery and I discuss the effective use of GLP-1 agonist medications like semaglutide and tirzepatide for sustainable weight loss. He emphasizes the need for a mindset shift, viewing these drugs as powerful tools to catalyze positive changes rather than easy fixes or crutches. Dr. Vickery explains that these medications provide leverage to implement foundational healthy habits and that the key to success lies in focusing on nutrient sufficiency, not just calorie restriction.
 
We also discuss concerns surrounding GLP-1 medications, such as the potential for muscle loss and the risk of regaining weight after discontinuing the drugs. He shares strategies to mitigate these issues, including resistance training, adequate protein intake, and gradual dose reduction when nearing one's goal weight.
 
Dr. Gus Vickery is an author, speaker, and the founder and directing physician of Authentic Health in Asheville, North Carolina. He established his practice with a commitment to delivering holistic, compassionate, and evidence-based care.
 
Thank you to our sponsors for making this episode possible:
Quicksilver: Visit quicksilverscientific.com/nat and use code Nat for 10% off your first purchase of PushCatch® Liver Detox.
Neurohacker Collective: Visit neurohacker.com/nathalie and use code NATHALIE
Inside Tracker: Use NIDDAM to save 10% at https://www.insidetracker.com
 
Find more from Dr. Gus Vickery: 
Website: https://drgusvickery.com/ 
Authentic Health Book: https://drgusvickery.com/book/ 
Instagram: @drgusvickerymd 
Youtube: The Family Doctor



Find more from Nathalie:
YouTube: https://www.youtube.com/channel/UCmholC48MqRC50UffIZOMOQ 
Join Nat’s Membership Community: https://www.natniddam.com/bsp-community 
Sign up for Nats Newsletter: https://landing.mailerlite.com/webforms/landing/i7d5m0 
Instagram: https://www.instagram.com/nathalieniddam/ 
Website: www.NatNiddam.com   
Facebook Group: https://www.facebook.com/groups/biohackingsuperhumanperformance 



What We Discuss: 
04:00 Understanding the Power of Peptides
07:45 The Underlying Benefits of Peptides
12:59 Addressing Concerns about Side Effects
29:06 The Right Way to Use Peptides
30:06 Hormone Therapy and Peptides
34:12 Nutrient Sufficiency and Protein
41:17 The Impact of Fasting and Gut Health
45:33 Addressing Microbiome Balance
58:56 The Pace of Fat Loss and Patience
59:42 Pushing Through Plateaus and Delicate Nervous System
01:07:13 Managing Hormetic Stress and Resting the Nervous System
01:09:00 Choosing Carbs or Fats and Individualization
 
Key Takeaways:
Peptides can be a powerful tool for improving body composition and metabolic health.
It is important to understand the proper use of peptides and not rely on them as a quick fix or easy way out.
Peptides have a range of benefits, including improving insulin sensitivity and reducing fatty liver disease.
Concerns about side effects and risks should be weighed against the potential benefits and individual circumstances