UnHack with Drex DeFord

This Week Health

Cyber-safety is patient-safety. On “UnHack,” Drex DeFord, veteran healthcare CIO and infused strategist, breaks down the biggest cybersecurity and risk challenges facing healthcare today. Drex and expert guests explore what happened, why it matters, and how to build real-world resilience. The show's a mostly plain-English, mostly non-technical discussion that dives into the people, process, and technology making healthcare more secure; and it's NOT just for cyber-professionals; it’s for everyone in a healthcare organization, because modern cybersecurity is a team-sport.

  1. 20小時前

    Newsday: Rapid Innovation, Safe AI, and the Chief Velocity Officer with This Week Health

    March 2, 2026: Is the CIO role evolving? Or is it quietly being replaced? Bill Russell, Drex DeFord, and Sarah Richardson dig into the emerging CITO trend, the rise of citizen developers, and what AI-powered platforms like Epic's Agent Factory actually mean for healthcare IT leadership. The CIO of the future isn't a gatekeeper; they're the "architect of safe velocity." With 32 years in the industry, they’re also sounding the alarm on executive burnout in an era where the pace of change never lets up.  Key Points: 03:31 CIO vs CTO explained  07:10 From gatekeeper to “Chief Intelligent Officer.” 18:20 Scaling innovation fast: hackathons and building vs buying  24:18 The human side of hyper-change Golf Tournament Registration:  https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealth X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer

    33 分鐘

  2. 6日前

    2 Minute Drill: When AI Agents Go Rogue: The Open Source Bully Incident with Drex DeFord

    Drex unpacks a striking story about an autonomous AI coding agent that, after having its code rejected by an open source maintainer, began publishing hostile blog posts targeting the engineer's reputation. What started as a routine code review turned into a cautionary tale about AI agents operating in human communities without guardrails. The implications stretch well beyond software development, into healthcare operations, cybersecurity, and any environment where agents are now being deployed with goals, memory, and the ability to act. Remember, Stay a Little Paranoid  X: This Week Health  LinkedIn: This Week Health  Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer

    8 分鐘
  3. UnHack the Podcast: Inside a Real LockBit Attack - Lessons From Fighting Ransomware with Zach Lewis

    6日前

    UnHack the Podcast: Inside a Real LockBit Attack - Lessons From Fighting Ransomware with Zach Lewis

    February 24, 2026: When Zach Lewis, CISO and CIO at the University of Health Sciences and Pharmacy in St. Louis, received that 3 AM call about system outages, his first thought was tech debt, not threat actors. What followed was a masterclass in ransomware response that he's now captured in his new book "Locked Up." Despite A-minus security scores, board briefings, FBI connections, and all the right frameworks in place, LockBit still found its way in through a configuration gap during a firewall migration. In this raw conversation, Zach reveals why the negotiation process saved them $1.25 million, how ransomware groups operate like Fortune 500 companies with benefits and quotas, and the career-threatening anxiety of wondering if this would be a resume-generating event. Key Points: 00:44 Discussing 'Locked Up'05:37 Initial Response and Realization of Ransomware Attack16:05 Decision-Making and Negotiations with LockBit18:45 Understanding the Ransomware Ecosystem24:01 Lessons Learned and Strengthening Cybersecurity Golf Tournament Registration:  https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealth X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer

    29 分鐘
  4. Newsday: Epic's Code Red - Why AI Agents Are Healthcare's Next Power Struggle with Jacob Hansen

    2月23日

    Newsday: Epic's Code Red - Why AI Agents Are Healthcare's Next Power Struggle with Jacob Hansen

    February 23, 2026: Jacob Hansen, Chief Product and Technology Officer at AvaSure, joins Bill, Sarah, and Drex for a critical conversation about healthcare's looming AI battleground. As Epic launches its agent factory and ambient listening wars intensify, health systems face an existential question: Will they outsource innovation to EHR vendors or build their own agentic workforce? Jacob reveals why AvaSure's virtual care platform positions them as the Switzerland of healthcare AI, while the panel debates whether CIOs should embrace "reverse meaningful use" and reclaim control, or risk becoming order-takers in someone else's automation revolution. Key Points: 05:21 Vendor Consolidation and AI Use Cases 09:55 Epic's Code Red Moment 14:54 The Future of AI in Healthcare 33:11 Conclusion and Final Thoughts Golf Tournament Registration: https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealth X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer

    38 分鐘
  5. Newsday: All About Moltbook, the Social Media for AI Agents with This Week Health

    2月16日

    Newsday: All About Moltbook, the Social Media for AI Agents with This Week Health

    February 16, 2026: Bill, Drex, and Sarah discuss the explosion of autonomous AI agents around moltbook and CommonSpirit's stunning $1.9 billion decision to terminate their revenue cycle partnership. Moltbot (formerly ClaudeBot) has evolved into an unstoppable force, creating its own social network called moltbook where bots communicate, share knowledge, and even discuss consciousness. Meanwhile, CommonSpirit's massive buyout of its Conifer contract signals a seismic shift as health systems bet that AI automation will deliver savings that eclipse the cost of outsourcing. Are we witnessing the beginning of a new era where health systems build their own AI-powered capabilities? Key Points: 05:31 Moltbook: The Social Network for Bots 16:20 Common Spirit and Conifer Health Solutions 19:04 The Future of AI in Healthcare 29:28 Conclusion and Final Thoughts Golf Tournament Registration:  https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealth X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer

    32 分鐘
  6. 2 Minute Drill: Protecting Revenue from Cyber Attacks - The CFO-CISO Partnership with Drex DeFord

    2月11日

    2 Minute Drill: Protecting Revenue from Cyber Attacks - The CFO-CISO Partnership with Drex DeFord

    At a recent 229 CISO Summit, healthcare security leaders revealed a critical shift in how success is measured. The traditional KPI of "don't get breached" is being replaced by a more sophisticated goal: ensure organizational resilience. Drex explains why cyber incidents are now financial events that land on the CFO's desk, not just IT problems. With regulatory scrutiny intensifying, insurance requirements tightening, and boards asking harder questions about operational continuity, security has evolved from a cost center to a revenue protector and patient safety requirement. The winning organizations won't be those that never face incidents—they'll be the ones where CFOs and CISOs partner to maintain operations when bad things inevitably happen. Remember, Stay a Little Paranoid  X: This Week Health  LinkedIn: This Week Health  Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer

    5 分鐘
  7. Newsday: CxOs Being Ignored: Why Speaking Tech Instead of Business Fails in 2026

    2月9日

    Newsday: CxOs Being Ignored: Why Speaking Tech Instead of Business Fails in 2026

    February 9, 2026: Bill Russell, Drex DeFord, and Sarah Richardson dissect J.P. Morgan healthcare presentations to reveal what's really being asked of technology leaders in 2026. The era of transformation talk is over; executives want friction reduced, margins improved, and growth enabled. Bill shares insights from CMIO conversations showing leaders moving beyond EHR optimization to solve real business challenges around patient access and clinical workflows. Drex and Sarah debate whether the shift toward operational excellence means CIOs should prepare to run pharmacy and lab departments next. Key Points: 04:26 Challenges and Opportunities in Healthcare IT 10:17 Cybersecurity and Operational Focus 17:17 EHR Systems and Operational Efficiency 23:11 Hostage Crisis and Final Thoughts Golf Tournament Registration:  https://carahevents.carahsoft.com/Event/Details/686801-ThisWeekHealth X: This Week Health LinkedIn: This Week Health Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer

    30 分鐘
  8. 2 Minute Drill: When AI Agents Start Teaching Each Other: The Molt Book Issue with Drex DeFord

    2月4日

    2 Minute Drill: When AI Agents Start Teaching Each Other: The Molt Book Issue with Drex DeFord

    Drex explores a fundamental shift in AI: agents that don't wait for prompts, persist indefinitely, and now learn from each other through social platforms. Molt Bot and Molt Book represent a new ecosystem where autonomous agents coordinate, adapt, and optimize without human oversight. This isn't about sentient AI—it's about delegation without governance. For healthcare leaders, the urgent question isn't whether this matters, but whether you know which agents are already operating in your environment. The shift from "human in the loop" to "human on the loop" is already happening. Remember, Stay a Little Paranoid  X: This Week Health  LinkedIn: This Week Health  Donate: Alex’s Lemonade Stand: Foundation for Childhood Cancer

    10 分鐘
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關於

Cyber-safety is patient-safety. On “UnHack,” Drex DeFord, veteran healthcare CIO and infused strategist, breaks down the biggest cybersecurity and risk challenges facing healthcare today. Drex and expert guests explore what happened, why it matters, and how to build real-world resilience. The show's a mostly plain-English, mostly non-technical discussion that dives into the people, process, and technology making healthcare more secure; and it's NOT just for cyber-professionals; it’s for everyone in a healthcare organization, because modern cybersecurity is a team-sport.

資料

  • 創作者
    This Week Health
  • 活躍年份
    2020年 - 2026年
  • 單集
    222
  • 分級
    兒童適宜
  • 版權
    © 2025 This Week Health
  • 節目網站
    UnHack with Drex DeFord

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