Biohacking Beauty: The Anti-Aging Skincare Podcast

Young Goose
  • 5.0 (1)
  • ALTERNATIVE HEALTH
  • UPDATED WEEKLY

Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond "single-molecule" trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ. We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, we translate complex research into actionable strategies for biological recalibration. From the 12 Hallmarks of Aging to the latest in bio-harmonizing lifestyle shifts, Biohacking Beauty provides the molecular tools and insights needed to align your skin’s appearance with your body’s peak biological potential.

  1. 3 DAYS AGO

    Dr. Alan Bauman: Why Biohackers Are Losing Their Hair Faster Than Everyone Else

    A lot of us treat hair loss the way skincare treats wrinkles, as a cosmetic problem to cover up. But almost every case of thinning, recession, or shedding has something deeper driving it, and by the time it shows up in the mirror, a significant amount of density is already gone. We at Young Goose believe that beauty is whole body care, and hair is one of the most metabolically active tissues in the body. It is also one of the first places systemic stress, hormone shifts, nutrient deficiencies, and inflammation show up. In this episode, Dr. Alan Bauman joins us to break down the biology of hair aging and the protocols that actually move the needle. Dr. Bauman is the founder of Bauman Medical in Boca Raton and one of the pioneers of modern hair restoration, with nearly three decades of clinical practice and more than 35,000 patients treated. His core message is simple and urgent: time equals follicles. Every week of delay is density you do not get back. And most people have no idea it is happening until the loss is already visible. We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover the hidden hair loss risks of GLP-1s and testosterone optimization, the precision diagnostics replacing guesswork, and the red light therapy details almost no one talks about. Let's dive in! What's Discussed: (2:20) How Dr. Bauman became a hair restoration pioneer and the patient who changed everything.(9:50) Why hair is an emotional organ and a biomarker for systemic health.(12:14) Time equals follicles: why every week of delay costs you density.(13:38) The mechanism of androgenetic alopecia and how DHT miniaturizes the follicle.(16:30) Why DHT is not the only driver: stress, inflammation, nutrient deficiency, and GLP-1s.(18:55) The hidden hair loss risks of weight loss peptides and caloric deficits.(21:06) Precision diagnostics: AI-powered microscopy, DNA testing, and preservation first.(23:36) What genetic testing actually tells us about your DHT metabolism pathways.(29:40) Minoxidil and finasteride explained, and why oral microdose is the modern approach.(32:20) Dutasteride, topical finasteride, and when to escalate.(39:41) Copper tripeptide, zinc thymulin, and the peptides with real hair growth data.(42:18) The hair loss side effect of TRT and hormone optimization nobody warns you about.(48:09) Red light therapy for hair: the science, the studies, and what actually works.(52:00) Wavelength precision, power density, and why most devices will not move a follicle.(59:06) Why movement destroys the premise of photobiomodulation.(1:04:36) PRP and modern dual spin protocols for hair regeneration.(1:08:28) Autologous hair follicle stem cell banking and the future of restoration. Find more from Young Goose: Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareVampire Exosomes: Professional Exosome Serum for Regeneration and Post-Treatment Recovery https://younggoose.com/products/vampire-exosomes  Find more from Dr. Alan Bauman: Instagram: @dralanbauman Youtube:  @AlanBaumanMD   X: @DrAlanBauman Facebook: Bauman Medical Group Shop: https://dralanbauman.com/ Website: https://www.baumanmedical.com/

    1hr 18min

  2. 8 APR

    The NAD+ Thief Your Skin Can't Escape: CD38, Zombie Cells, and the Decline

    Most people know NAD+ as a supplement trend. But very few understand what's actually happening inside their skin cells when it runs out or what's stealing it in the first place. By the time you're 45, you've lost half of the molecule that powers virtually every function keeping your skin young. Sadly, it only gets worse from there. The enzyme your skin uses for DNA repair can wipe out up to 90% of what's left after a single afternoon in the sun. This isn't a slow, graceful decline. It's a collapse happening beneath the surface long before the wrinkles appear. In this episode, we will nerd out and break down exactly why NAD+ disappears, who the thieves are, and what the science actually says about getting it back. From the sirtuin-PARP-CD38 trifecta to the zombie cell feedback loop that accelerates the drain with age, this is the most complete picture of NAD+ and skin aging we've put together to date. We also cover the real differences between NMN, NR, and niacin, why the precursor you choose actually matters, and what to stack with it to protect your methylation pathways. Ready to nerd out in this with us? Let's dive in! What's Discussed: (4:00) The number that changes how you think about skin aging.(6:03) What NAD+ actually does and why "rechargeable battery" undersells it.(8:18) The three enzyme families consuming your NAD+ as a substrate.(8:23) Sirtuins: the police of your cells and what they cost you.(9:42) PARPs: the fire brigade and why one sunburn nearly wipes you out.(11:16) CD38: the NAD+ Pac-Man that gets worse with age.(15:10) The five-fold decline: what the 2012 tissue study actually found.(16:15) CD38 and the zombie cell feedback loop driving the decline.(19:39) What the depletion actually looks like in the mirror.(28:04) Why NAD+ decline is reversible & supplementation deep dive.(28:41) NMN: how it works and what the studies actually show.(31:50) NR: the most clinically studied precursor and who it's best for.(33:27) Niacin: the $5 option and why most people can't tolerate it.(38:14) Why timing your NAD+ to your circadian rhythm matters.(38:35) TMG and methylation: what to stack and the two-to-one ratio. Learn more about NAD from our previous podcasts and videos: Previous NAD YouTube Videos: NAD+, Skincare Science + The Future of Skincare: https://www.youtube.com/watch?v=ZmwYLywwcsA Biohack Your Way to Better Skin - Benefits of NAD Boosting Supplementation for Skincare & Anti-Aging: https://www.youtube.com/watch?v=KIz5MvW7X1M Why Your NAD+ Supplement Isn't Helping Your Skin | The Truth: https://www.youtube.com/watch?v=euIj0eLt4Aw The Science Behind NAD+, Link Between NAD+ Skin Aging, Importance of Precursors: https://www.youtube.com/watch?v=wmsUeQklYY0 The NAD+ Protocol That Could Reverse Skin Aging (Doctors Won't Tell You) | Dr. Scott Sherr: https://www.youtube.com/watch?v=iYJgVSoj_XM Previous NAD Podcasts: NAD 101: Unlocking The Secrets To Youthful Skin: https://podcasts.apple.com/us/podcast/nad-101-unlocking-the-secrets-to-youthful-skin/id1552026927?i=1000652231123 The Relationship Between NAD+ and Your Skin, NAD+ Depletion, Bioavailability, Precursors, Sirtuins, and More: https://podcasts.apple.com/us/podcast/22-the-relationship-between-nad-and-your-skin/id1552026927?i=1000568088462 The Science Behind NAD+, the Link Between NAD+ and Skin Aging, and the Importance of Precursors: https://podcasts.apple.com/us/podcast/the-science-behind-nad-the-link-between-nad-and/id1552026927?i=1000615122098 Ben Azadi: How NAD+ Helps Reverse Aging + Skin Problems Connected to Deeper Health Issues: https://podcasts.apple.com/us/podcast/ben-azadi-how-nad-helps-reverse-aging-skin-problems/id1552026927?i=1000662495945 Turn Back the Clock: NAD and Skin Biohacking: https://podcasts.apple.com/us/podcast/turn-back-the-clock-nad-and-skin-biohacking/id1552026927?i=1000681105344 Research Studies Mentioned: Age-Associated Changes In Oxidative Stress and NAD+ Metabolism In Human Tissue: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042357 CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction: https://www.cell.com/cell-metabolism/fulltext/S1550-4131(16)30225-7 Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages: https://www.nature.com/articles/s42255-020-00305-3 Enhanced SIRT1 Activity Mitigates UVB-Induced Senescence in Dermal Fibroblasts: https://pubmed.ncbi.nlm.nih.gov/39401943/ Slc12a8 is a nicotinamide mononucleotide transporter: https://www.nature.com/articles/s42255-018-0009-4 The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: https://link.springer.com/article/10.1007/s11357-022-00705-1 Nicotinamide riboside and nicotinamide mononucleotide facilitate NAD+ synthesis via enterohepatic circulation: https://www.science.org/doi/10.1126/sciadv.adl5154 Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults: https://www.nature.com/articles/s41467-018-03421-7 Find more from Young Goose: Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareHead to younggoose.com/products/youth-body-cream for 20% offBody Cream: Head to younggoose.com/products/youth-body-cream for 20% off

    32 min

  3. 1 APR

    Dani Conway: The Gut-Liver Detox Connection & How Gut Issues Show Up As Skin Issues

    Most people treat their skin like a surface problem. But almost every persistent skin issue, from rosacea to eczema to accelerated aging, has something deeper driving it. That deeper driver is almost always the gut, the liver, or a backed-up detox pathway. We at Young Goose, always believe that skincare is whole body care and we want our community to identify the deeper causes of skin issues that products alone can’t fix. In this episode, functional nutrition practitioner Dani Conway joins us to break down why the skin is not the origin of the problem but the exit sign. When the body cannot eliminate toxins efficiently, they take the path of least resistance. For a lot of women, that path is the skin on their faces. Dani brings nearly 20 years of clinical practice to this conversation, along with a sharp, evidence-grounded perspective on why fixing hormones first is often the wrong starting point and what to address instead. We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover how to deal with food sensitivities, common misconceptions around hormones and blood sugar testing, and the use of GLP-1 and peptide use. Let’s dive in! What's Discussed: (0:57) How poor detoxification shows up on the skin. (2:09) The foundational actions to support detox. (5:44) The lymphatic system explained. (6:33) Why Dani stopped addressing hormones first. (8:01) Microplastics, endocrine disruptors, and chemicals women apply to their skin. (11:40) The gut-skin axis: How gut symptoms always end up on your face. (13:55) NAD, CD38, and why a bacterial infection in your gut affects cell energy. (16:59) Why peptides and NAD supplements don't work if the foundation isn't dialed in first. (21:26) Can you actually fix hormones or just manage them? (25:12) Real-world food sensitivity examples and how to figure out your personal triggers. (29:41) How to run an elimination diet correctly. (34:39) The big picture nobody talks about: it's not the food, it's the immune system. (36:06) The new science on acne: The bacteria and immune system response. (38:06) Hot take: Why immune optimization is the next mitochondria. (39:49) CGMs and skin aging: Why Dani actually pulls clients back from data obsession. (42:09) Fasting insulin ranges: Why the lab's "normal" range is dangerously wide. (43:35) The role of GLP-1s and how to use them as a therapy instead of a crutch. (45:12) Dani's hot take on berberine and leptin resistance. Find more from Young Goose: Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare Find more from Dani Conway: Instagram: @DaniConwayOfficialWebsite: https://nutritionthenaturalway.com/The Wellness Collective: https://nutritionthenaturalway.com/drop-the-weight-shred-the-fat/Weight Loss Accelerator Program: https://go.nutritionthenaturalway.com/wlaFree Complimentary Guide: https://go.nutritionthenaturalway.com/hhh

    58 min

  4. 25 MAR

    Skin Barrier Protocol: How One Reset Makes Every Other Skincare Step Work

    Most people think that the stinging feeling, redness or tightness are always good signs of skin detoxification. Tricky enough, it can look like ‘glass skin’ or skin renewal. However, almost always the temporary tight and bright skin is a skin barrier issue in disguise. Skin barrier damage is one of the most misread signals in skincare. It looks like purging but it is actually your skin telling you it has been pushed past its limit. It’s easy to think there’s no damage at all because overexfoliation can temporarily give a satisfying baby skin at the cost of long-term skin wellness. One of the best ways to distinguish normal skin stimulation versus barrier damage is to understand your skin biology. As Anastasia always says, "We're not chasing a 10-day glow. We're chasing a 10-year outcome." We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover what real skin barrier repair should feel like, the pillars of skin wellness, and how to listen better to your skin to train it to become more resilient. Resources mentioned: Barrier Protocol: https://www.younggoose.com/pages/barrier-protocol What's Discussed: (04:20-05:11) Why a weak skin barrier makes every other skincare step stop working (05:11-06:16) The four signs of barrier damage that looks like progress (06:16-08:29) What is a skin barrier and what happens when the lipid ratio breaks down (08:29-10:10) How barrier disruption can disguise as purging (10:10-13:00) A case study of laser-induced barrier damage and the cycle of over-treatment (13:00-15:11) The three pillars of skin wellness: performance, resilience, and longevity (15:11-16:52) What your skin should be able to do before you add any heavy stimulation (16:52-18:30) The three-step barrier reset protocol (18:30-20:30) Morning versus nighttime barrier: defense vs. repair (20:30-25:09) The truth about exfoliation culture and the glass skin trend (25:09-27:00) How to build an exfoliation schedule that works for your skin type Find more from Young Goose: VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare

    32 min

  5. 18 MAR

    Sleep Is Skincare: How Timing Unlocks Your Body's Best Skin Repair

    Did you know that the most powerful anti-aging protocol isn't about how long you sleep? It's about when. Getting eight hours of sleep for skincare feels like a tough feat to achieve especially when life gets in the way. By understanding how your skin begins its optimal repair time, it’s still possible to achieve the best skin results without the guilt of not sleeping enough. In our quest in finding the best skincare ingredient for our products, we discovered that hours of sleep do matter, but best skin results happen by following the skin’s optimal program sequences for deep repair. We go deeper into this in the latest episode of Biohacking Beauty: The Anti-Aging Skincare Podcast. We also cover how melatonin onset, circadian rhythm, growth hormones, and inflammation play a huge role in giving your skin the environment it needs to do its best work. What's Discussed: (1:54-5:09) Why sleep timing matters more than sleep hours for skin repair(07:01-15:19) The three repair windows your skin depends on every night: melatonin onset, growth hormone pulse, and barrier recovery(05:09-5:55) Why dull skin, slow healing, and crepey eyes are often a timing problem — not a product problem(13:28-17:10) How to build a recovery-first nighttime routine before adding any stimulation(37:47-40:47) The silk vs. cotton pillowcase: Which fabric choice is part of your skincare(43:29-47:36) Supplements that support skin repair at night(17:17-17:30) Red light therapy as the only exception to the no-stacking rule Resources mentioned: Sleep protocol: https://www.younggoose.com/pages/sleep-protocol Episode with Anastasia (BeautyFascia): https://podcasts.apple.com/us/podcast/anastasia-beauty-fascia-facial-fascia-and-massage Episode on Face Taping with Olga from Natural Face Bible: https://podcasts.apple.com/us/podcast/real-japanese-face-taping-explained-with-olga Find more from Young Goose: The Elastin Action Protocol → Engineered for Skin Navigating Elasticity ChangeThe Winter Skin Protocol → Build for How Skin Actually Behaves in WinterVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare

    47 min

  6. 11 MAR

    Alex Tarnava: What Hydrogen Really Does to Your Skin

    Molecular hydrogen is often described as a selective antioxidant, but that framing is incomplete. In this episode, we explore hydrogen as a mitochondrial hormetic signal that can influence redox balance, inflammatory regulation, and adaptive stress pathways. The key distinction is that delivery route changes mechanism. Oral, inhaled, and topical hydrogen act differently in the body, with different kinetics, tissue distribution, and biological implications. We dive deeper into this in the Biohacking Beauty Podcast with Alex Tarnava. We discuss why topical hydrogen is gaining attention for skin outcomes, how gut-mediated signaling may drive systemic effects, and why interpreting evidence requires understanding study design, delivery method, and real-world product variability. WHAT’S DISCUSSED: (04:52) Why hydrogen is not a traditional antioxidant and what that actually means biologically (06:17) How different delivery routes change tissue targeting and systemic signaling (10:09) Why skin aging and inflammatory conditions behave more like a systems problem than a single pathway (15:10) How mild oxidative stress can activate endogenous antioxidant production (16:05) The hidden risk of reductive stress from excessive antioxidant use (17:59) Why inflammation must be regulated rather than suppressed for long-term tissue repair (28:52) The gut-driven mechanisms that may influence visible skin outcomes (29:42) How corporate-owned research and investigator-led studies shape the hydrogen evidence landscape (37:25) Why exaggerated longevity claims distort innovation and erode trust (50:49) The growing issue of counterfeit hydrogen products and what it signals about market maturity Find more from Young Goose: The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare Find more from Alex Tarnava: Website: https://hydrogenwatertablets.com https://alextarnava.com Instagram: https://www.instagram.com/alextarnava

    59 min

  7. 4 MAR

    Dr. Scott Sherr: Why Chronic Stress Disrupts Mitochondria and Accelerates Visible Skin Aging

    Chronic stress isn’t just a mental or emotional burden. It creates a biological cascade that disrupts mitochondrial function, accelerates inflammation, and shows up visibly in the skin long before deeper symptoms appear. We dive deeper into this in the Biohacking Beauty Podcast with Dr. Scott Sherr. We also talk about the sympathetic spiral of doom, why skin reflects mitochondrial decline before other symptoms appear, and why sequencing interventions matter more than intensity. Dr. Scott Sherr is a board-certified internal medicine physician certified in Health Optimization Medicine (HOMe) and a specialist in Hyperbaric Oxygen Therapy. He is the COO of Troscriptions and focuses clinically on mitochondrial health, stress physiology, and advanced recovery protocols. What's Discussed: (01:52) Why chronic stress is not just mental and directly impacts cellular energy(05:17) How modern life keeps the nervous system stuck in chronic fight or flight(07:25) Cortisol and stress hormones disrupting mitochondria and accelerating skin aging(11:16) Why skin aging is often the first visible sign of mitochondrial decline(24:16) The sympathetic spiral of doom explained through energy loss and stress signaling(27:14) Why stress reduction and mitochondrial support must happen at the same time(46:22) Why aggressive skincare and biohacking fail without mitochondrial resilience(50:35) Hyperbaric oxygen therapy, sequencing, and why timing matters more than intensity Find more from Young Goose: The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare Find more from Dr. Scott Sherr: Website: https://troscriptions.com LinkedIn: @troscriptions Instagram: @drscottsherr @troscriptions Facebook: @Troscriptions Youtube: @troscriptions Tiktok: @troscriptions

    1hr 13min

  8. 25 FEB

    Anastasia (Beauty Fascia): Facial Fascia and Massage + Lymphatic Drainage for Younger-Looking Skin

    Fascia is one of the most overlooked conversations in skin aging. We spend so much time thinking about collagen, serums, injectables, and trending tools, but very few people are talking about the structural system underneath the skin that influences how we actually age. If you are dealing with under-eye puffiness, jaw tension, posture changes, facial asymmetry, or feeling like your face looks more tired than it should, this episode explores a deeper layer of the conversation. We dive into fascia, fluid movement, breathing patterns, and why your neck and jaw may be playing a much bigger role in your appearance than you realize. In this conversation, we break down what fascia really is in simple terms and how it connects to collagen production, lymphatic drainage, nervous system regulation, and facial structure over time. Anastasia is a board-certified Structural Integration Therapist trained in kinesiology, facial muscle neuro rehabilitation, neurovascular release, myofascial release, traditional Chinese medicine, and acupressure. Over the past five years, she has pursued global mentorships and seminars focused on structural and facial regeneration, bringing together multiple disciplines to support facial health, tissue quality, and overall structural balance. To watch this episode on Youtube click here: https://youtu.be/KRs4dlmfj8s What's Discussed: (11:41) Why facial massage does not stretch skin and how tissue actually adapts(19:38) Under eye puffiness as a drainage issue, not a skin problem(23:12) Collagen cross linking and why fibroblasts avoid rebuilding on damaged matrix(27:23) Glymphatic dysfunction and how poor brain drainage shows up in the face(51:52) What happens to circulation and lymphatic flow when muscles are paralyzed with Botox(53:52) Why mewing fails without addressing neck tension and structural foundation(01:12:23) Phone posture, forward head position, and structural facial aging(01:14:39) Aging as a structural shift before wrinkles ever appear Find more from Young Goose: The Elastin Action Protocol → Engineered for Skin Navigating Elasticity ChangeThe Winter Skin Protocol → Build for How Skin Actually Behaves in WinterVAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment RecoveryUse code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincare Find more from Anastasia (Beauty Fascia): Website: https://anastasia.beautyInstagram: @anastasiabeautyfasciaYoutube: @anastasiabeautyfasciaTikTok: @anastasiabeautyfascia

    1hr 24min
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About

Welcome to Biohacking Beauty, the definitive exploration of skin health through the lens of longevity medicine and cellular biology. Hosted by the founders of Young Goose, Amitay Eshel and Anastasia Khodzhaeva, this podcast moves beyond "single-molecule" trends to uncover the multi-mechanism protocols required to optimize the body’s largest organ. We bridge the gap between systemic longevity research and topical application. By hosting world-renowned experts in mitochondrial health, epigenetic signaling, and regenerative medicine, we translate complex research into actionable strategies for biological recalibration. From the 12 Hallmarks of Aging to the latest in bio-harmonizing lifestyle shifts, Biohacking Beauty provides the molecular tools and insights needed to align your skin’s appearance with your body’s peak biological potential.

Information

  • Creator
    Young Goose
  • Years Active
    2021 - 2026
  • Episodes
    247
  • Rating
    Clean
  • Copyright
    © Copyright 2026 Young Goose

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