CRITKNOW

Bharath Kumar Tirupakuzhi Vijayaraghavan

Our take on the latest critical care evidence with deep insights on methods, interpretation, clinical relevance and so much more! CRITKNOW is co-hosted by Bharath Kumar Tirupakuzhi Vijayaraghavan and Ramesh Venkataraman. Bharath is a mid-career clinician–researcher with a primary focus on improving outcomes from critical illness in patients in low- and middle-income countries (LMICs). He is also deeply passionate about teaching evidence-based medicine and helping clinicians interpret and apply emerging evidence in patient care. You can learn more about his work here: https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf Ramesh is American Board–certified in Internal Medicine, Critical Care Medicine, and Neurocritical Care. He is also a senior researcher with a special interest in acute kidney injury and renal replacement therapy. A highly respected teacher and educator, he has a unique ability to integrate emerging evidence into bedside clinical practice. You can learn more about his work here: https://icuconsultants.com/dr-ramesh-venkataraman/ Bharath and Ramesh are both Senior Consultants in the Department of Critical Care Medicine at Apollo Hospitals, Chennai and affiliated with Chennai Critical Care Consultants Private Limited, an academic critical care group practice (https://icuconsultants.com/). Bharath is also affiliated with the University of Edinburgh as a Clinical Research Fellow (https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar) Views expressed are personal.

Episodes

  1. 6 DAYS AGO

    Ketamine vs. Etomidate: the RSI trial

    Welcome to the 2nd episode of CRITKNOW! In this episode we are focusing on the RSI trial that compared Ketamine vs. Etomidate for intubating critically ill patients. CRITKNOW will focus on a variety of themes related to the practice of evidence-based critical care and is co-hosted by Bharath Kumar Tirupakuzhi Vijayaraghavan and Ramesh Venkataraman. Bharath is a mid-career clinician–researcher with a primary focus on improving outcomes from critical illness in patients in low- and middle-income countries (LMICs). He is also deeply passionate about teaching evidence-based medicine and helping clinicians interpret and apply emerging evidence in patient care. You can learn more about his work here: https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf Ramesh is American Board–certified in Internal Medicine, Critical Care Medicine, and Neurocritical Care. He is also a senior researcher with a special interest in acute kidney injury and renal replacement therapies. A highly respected teacher, he has a unique ability to integrate emerging evidence into bedside clinical practice. You can learn more about his work here: https://icuconsultants.com/dr-ramesh-venkataraman/ Bharath and Ramesh are both Senior Consultants in the Department of Critical Care Medicine at Apollo Hospitals, Chennai and affiliated with Chennai Critical Care Consultants Private Limited, an academic critical care group practice (https://icuconsultants.com/). Bharath is also affiliated with the University of Edinburgh as a Clinical Research Fellow (https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar) Views expressed are personal. We are also complementing the content here with a blog: https://ccmevidence.blog/ that will discuss specific methodological and analytical issues.

    28 min
  2. 14 MAR

    Andromeda-Shock-2

    Welcome to the first episode of CRITKNOW! CRITKNOW will focus on a variety of themes related to the practice of evidence-based critical care and is co-hosted by Bharath Kumar Tirupakuzhi Vijayaraghavan and Ramesh Venkataraman. Bharath is a mid-career clinician–researcher with a primary focus on improving outcomes from critical illness in patients in low- and middle-income countries (LMICs). He is also deeply passionate about teaching evidence-based medicine and helping clinicians interpret and apply emerging evidence in patient care. You can learn more about his work here: https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf Ramesh is American Board–certified in Internal Medicine, Critical Care Medicine, and Neurocritical Care. He is also a senior researcher with a special interest in acute kidney injury and renal replacement therapies. A highly respected teacher, he has a unique ability to integrate emerging evidence into bedside clinical practice. You can learn more about his work here: https://icuconsultants.com/dr-ramesh-venkataraman/ Bharath and Ramesh are both Senior Consultants in the Department of Critical Care Medicine at Apollo Hospitals, Chennai and affiliated with Chennai Critical Care Consultants Private Limited, an academic critical care group practice (https://icuconsultants.com/). Bharath is also affiliated with the University of Edinburgh as a Clinical Research Fellow (https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar) Views expressed are personal. We are also complementing the content here with a blog that will discuss specific methodological and analytical issues. Here is the link to the blog on win ratios: https://ccmevidence.blog/2026/03/18/win-ra... and to the one on composite outcomes: https://ccmevidence.blog/2026/03/28/compos... Takeaways Evolution of goal-directed resuscitationUnderstanding win ratio and composite outcomes Chapters 00:00 Introduction to CRITKNOW Podcast07:10 Andromeda 2 Shock Trial Overview14:18 Composite Outcomes and Win Ratio19:59 Secondary Outcomes and Results

    29 min

About

Our take on the latest critical care evidence with deep insights on methods, interpretation, clinical relevance and so much more! CRITKNOW is co-hosted by Bharath Kumar Tirupakuzhi Vijayaraghavan and Ramesh Venkataraman. Bharath is a mid-career clinician–researcher with a primary focus on improving outcomes from critical illness in patients in low- and middle-income countries (LMICs). He is also deeply passionate about teaching evidence-based medicine and helping clinicians interpret and apply emerging evidence in patient care. You can learn more about his work here: https://www.researchgate.net/profile/Bharath-Kumar-Tirupakuzhi-Vijayaraghavan?ev=hdr_xprf Ramesh is American Board–certified in Internal Medicine, Critical Care Medicine, and Neurocritical Care. He is also a senior researcher with a special interest in acute kidney injury and renal replacement therapy. A highly respected teacher and educator, he has a unique ability to integrate emerging evidence into bedside clinical practice. You can learn more about his work here: https://icuconsultants.com/dr-ramesh-venkataraman/ Bharath and Ramesh are both Senior Consultants in the Department of Critical Care Medicine at Apollo Hospitals, Chennai and affiliated with Chennai Critical Care Consultants Private Limited, an academic critical care group practice (https://icuconsultants.com/). Bharath is also affiliated with the University of Edinburgh as a Clinical Research Fellow (https://inflammation-research.ed.ac.uk/research/research-groups/dr-bharath-kumar) Views expressed are personal.