Thriving at PSOM

PSOM's Office of Academic Affairs

Thriving at PSOM is a new podcast by and for our faculty, where we discuss topics that matter to us with school leadership, COAP members, and PSOM's amazing innovators. This is a chat amongst colleagues and friends, not an extension of policy. Go to our show notes for policy, Our host is Meryl Cohen, MD, Professor of Pediatrics, PSOM COAP Member, and Associate Dean of Faculty Development. Welcome!

  1. 20 MAR

    (Season 3, Ep. 8) From Discovery to First-in-Human Therapy: A Conversation with the Team Behind Infant KJ's Treatment

    What happens when medicine, technology, and innovative minds come together to save an individuals life? Baby KJ born in 2024 in Philadelphia with an extremely rare and life-threatening genetic disorder called CPS1 deficiency, which affects the body's ability to remove ammonia. In a combination of fortune, advancing technology, and a world class medical team, Dr. Kiran Musunuru, MD, PhD, MPH, ML, MRA, (Barry J. Gertz Professor for Translational Research, Director of the Penn Cardiovascular Institute's Genetic and Epigenetic Origins of Disease Program,  and Scientific Director of the Penn Center for Inherited Cardiovascular Disease, Hospital of the University of Pennsylvania), and Dr. Rebecca Ahrens-Nicklas, MD, PhD, (Assistant Professor of Pediatrics (Human Genetics), Director of Gene Therapy for Inherited Metabolic Disorders Frontier Program at CHOP, and Associate Chief for Research, Division of Human Genetics at CHOP and UPenn) were able to bring their years of research in personalized gene-editing therapy using CRISPR to a first in-human innovation. Alongside host Meryl Cohen, they discuss how CRISPR and gene therapy is sitting at the forefront of medical innovation. highlighting how the technology was used to help baby KJ. They also talk about the intensive processes that led up to the fortunate situation of KJ being born in the PennMedicine system. They talk about balancing ethics and patient confidentiality with conveying the story of a true medical breakthrough, and talk about what is next for KJ, gene therapy at large, and their own research. This is story is about the success of years of research, work, and a testament to the entire team of medical professionals at CHOP and HUP seeing patients every day that making innovation possible.

    46 min
  2. (Season 3, Ep. 1) On the Cutting Edge: Utilizing Artificial Intelligence in Medicine as a Leader

    07/02/2025

    (Season 3, Ep. 1) On the Cutting Edge: Utilizing Artificial Intelligence in Medicine as a Leader

    What happens when a new tool emerges and its potential impact is still becoming apparent? Artificial Intelligence is one of the most controversial and least understood technologies emerging today. Our guest Ethan Mollick is the Ralph J. Roberts Distinguished Faculty Scholar and Associate Professor at the Wharton School of the University of Pennsylvania, where he studies the effects of artificial intelligence on work, entrepreneurship, and education. His academic research has been published in leading journals, and his work on AI is widely applied, leading him to be named one of TIME Magazine's Most Influential People in Artificial Intelligence. Ethan also writes to a wider audience about AI, including in his book, Co-Intelligence, a New York Times bestseller. Alongside host Meryl Cohen, they discuss how current AI tools contrast with existing technologies used in healthcare and where that technology is going. Ethan shares use cases that have highlighted what AI can do to enhance our work, and they talk how to make this tech work with us and not against us. They also discuss how learners may already be using and how academics should approach AI to improve outcomes in their daily tasks. They also discuss how med students may be using AI and what effects it has on their learning. In a unique culmination for the episode, Ethan shows how tools today can synthesize a published paper into study guides, FAQs, and even a miniature podcast!

    32 min

About

Thriving at PSOM is a new podcast by and for our faculty, where we discuss topics that matter to us with school leadership, COAP members, and PSOM's amazing innovators. This is a chat amongst colleagues and friends, not an extension of policy. Go to our show notes for policy, Our host is Meryl Cohen, MD, Professor of Pediatrics, PSOM COAP Member, and Associate Dean of Faculty Development. Welcome!

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