Giants Shoulder

Evan McGloughlin

A Biology & Consciousness podcast chronicling the bio-singularity. 3x times per week I speak with leading scientists at the bleeding edge of Neuroscience, Consciousness and Biology. No idea is too strange, tackled with genuine curiosity and technical rigour. Come follow the journey as I have my brain melted and ontology warped on a regular basis. Evan has a Neuroscience degree from Trinity College Dublin and is founder of Giants Shoulder.

  1. 7 h fa

    #156 - Meet The Greatest Time Neuroscientist You’ve Never Heard Of

    🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/join Dean Buonomano is a UCLA neuroscientist and one of the first researchers to ask how the brain encodes time. His work overturned a century-old assumption — that somewhere in your head sits a central clock — by showing that timing falls out of the dynamics of neural circuits themselves. He wrote the bestseller Your Brain Is a Time Machine, then took the argument to physics, co-authoring a paper with Carlo Rovelli on whether the past still exists. He is a presentist in a field that mostly isn't. Expect to learn: - The clockless brain: why there is no central timer anywhere in your head - Timing in a dish: how isolated brain tissue can be taught intervals - Death and religion: how foresight forced our ancestors to invent the afterlife - The ten-second test: the one simple thing no language model can do - Pause the computer: the thought experiment that breaks state-based theories of consciousness SPONSORS Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulder GS EPISODES MENTIONED György Buzsáki - Meet the Neuroscientist Who Discovered That Waves Produce Memory, Spacetime and Consciousness: https://youtu.be/95FFRTIiLDY Joseph LeDoux - Meet The World's Greatest Emotion Neuroscientist You've Never Heard Of: https://youtu.be/u_yCcxQsKn0 Michael Levin - Michael Levin: Bioelectricity, Morphogenesis, Platonic Spaces & Xenobots: https://youtu.be/LTBZRVKUwyM Michael Levin & Earl Miller - Meet the Scientist Showing Every Cell In Your Body is Conscious!: https://youtu.be/eNi-_2cOVtc Anil Seth - No. 1 Consciousness Expert: Optical Illusions that Prove Reality is a Lie, Emotions, Books and AI!: https://youtu.be/lOSA06K0l1o GUEST LINKS UCLA Neurobiology Profile: https://neurobio.ucla.edu/people/dean-buonomano-phd Buonomano Lab: http://www.buonomanolab.com/ X: https://x.com/DeanBuono Bridging the Neuroscience and Physics of Time (with Carlo Rovelli): https://arxiv.org/abs/2110.01976 LISTEN ON YouTube - https://youtu.be/G2LaKtxUng0 Apple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249 SKOOL Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:01 The Brain Has No Central Clock 0:04:17 How Neural Population Clocks Work 0:05:40 Teaching Brain Tissue To Tell Time 0:06:57 Prediction Is Really About When 0:09:10 Even Bacteria Keep Time 0:10:27 Mental Time Travel Built Civilisation 0:11:39 Realising You'll Die Invented Religion 0:14:57 Squirrels Don't Actually Plan Ahead 0:18:19 Waking Up Before Your Alarm 0:23:29 Why Time Is Central To Consciousness 0:24:01 Block Universe vs Only Now 0:29:24 The Runner Who Lost Time 0:33:18 Why Marathons Destroy Time Perception 0:37:18 The Memories With No Timestamp 0:42:02 Your Brain Runs Many Clocks 0:43:31 AI Cannot Wait Ten Seconds 0:45:38 How Transformers Deleted Time 0:49:29 What If You Paused The Computer? 0:53:05 Could We Ever Build Conscious AI? 0:58:17 Arguing About Time With Carlo Rovelli 1:01:40 A Time Traveller Would Prove Me Wrong 1:07:05 You Can't Measure Time With Time 1:12:25 Which Theory Of Consciousness Is Right? 1:21:55 Why We Invented The Soul .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

  2. 3 gg fa

    #155 - Meet The World’s Greatest Endogenous DMT Psychedelic Scientist You've Never Heard Of

    🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/join Steven Barker is the chemist who has spent fifty years proving your brain makes its own psychedelic. He built the mass-spectrometry methods sensitive enough to find DMT in living tissue, and showed it sits in the brain at concentrations rivalling serotonin and dopamine. In 1981 the war on drugs cut his funding and the work stopped for fifteen years. He also synthesised his own supply — and took it. Expect to learn: - The locked cabinet: what his mentor kept behind two locks, and why Barker raided it - The missing neurotransmitter: why DMT meets every formal criterion and nobody noticed - Machine elves: why he calls the term marketing rather than science - DMT immunity: the lab technician who took a full dose and felt nothing - Receptors inside the neuron: the 2023 finding that explains the neuroplasticity SPONSORS Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial - https://app.macrofactor.com/mfgiants GS EPISODES MENTIONED Andrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDA Rick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYsc Dennis McKenna - Dennis McKenna: "I've Spent 50 Years Investigating The Entities That Exist Within Ayahuasca": https://youtu.be/gTSBhfZhuD8 David Nichols - Meet The Greatest Living Psychedelic Scientist You've Never Heard Of: https://youtu.be/6umTgXsW1lQ GUEST LINKS ResearchGate Profile: https://www.researchgate.net/scientific-contributions/Steven-A-Barker-2164230436 N,N-Dimethyltryptamine, an Endogenous Hallucinogen (2018 review): https://doi.org/10.3389/fnins.2018.00536 A Critical Review of Endogenous DMT in Humans 1955-2010 (with Strassman): https://doi.org/10.1002/dta.422 LC/MS/MS Analysis of Rat Pineal Microdialysate (2013, the paper discussed on tape): https://doi.org/10.1002/bmc.2981 Administration of DMT in Psychedelic Therapeutics (2022 review): https://doi.org/10.1007/s00213-022-06065-0 LISTEN ON Spotify - https://open.spotify.com/show/5m3Gta5MtIYdk59pb2GJ7M Apple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249 SKOOL Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:15 50 Years Chasing One Molecule 0:06:37 Huxley, Osmond and the Birth of "Psychedelic" 0:08:01 The Schizotoxin Hypothesis That Started It All 0:10:54 Finding DMT in Everyone, Not Just Patients 0:11:56 How the War on Drugs Killed the Research 0:16:39 The 40 Years of Research We Lost 0:18:36 "Have You Ever Taken It Yourself?" 0:19:20 Inside the Locked Psychedelic Cabinet 0:20:22 The Overabundance He Didn't Want to Waste 0:22:51 Why He Won't Describe What He Saw 0:23:38 Set, Setting and the Expectancy Problem 0:27:16 Dennis McKenna Has Never Seen a Machine Elf 0:28:31 "Machine Elf" Was a Marketing Term 0:30:40 The Tryptamine Family Tree Explained 0:34:21 Bufotenine, 5-MeO-DMT and the Blood-Brain Barrier 0:38:36 DMT as a Working Neurotransmitter 0:41:34 "DMT Is the Missing Neurotransmitter" 0:44:56 You Have Two Brains - and the Gut Makes More 0:46:29 Pushing Back on Gallimore's Alien World 0:54:04 96% Say the Entity Was Conscious 0:57:52 Did the Caveman Experience an Alien? 0:59:07 "These Are Not Real Elves" 1:06:40 Are Some People Immune to DMT? 1:10:51 You Can't Build Tolerance to Your Own Neurotransmitter 1:15:46 The Receptors Hiding Inside Your Neurons 1:24:24 What a Psychedelic Overdose Actually Is .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

  3. 6 gg fa

    #154 Meet The Greatest End-Of-Life Scientist You’ve Never Heard Of

    🧠 JOIN THE GIANT'S SHOULDER FAMILYBecome a YouTube Member for exclusive episodes, early access + ad-free viewing 👇https://www.youtube.com/@thegiantsshoulder/joinAlexander Batthyány is the philosopher and psychologist who turned a deathbed anecdote into a science. He ran the first modern study of paradoxical lucidity, co-authored the field's founding definition with Bruce Greyson, and has now collected around 450 cases of severely demented patients unexpectedly getting their memory, speech and personality back. Victorian doctors documented the phenomenon at length and called it "lightening up before death"; twentieth-century medicine stopped writing it down because there was no way to phrase it in a case study. He is now working with a group at the Mayo Clinic to put cameras in patients' rooms so the episodes stop being missed. In one case a woman came back for two hours, discussed her own diagnosis, died — and imaging taken immediately afterwards showed no change whatsoever.SPONSORSGet One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqeGS EPISODES MENTIONEDRick Strassman - Meet The Father Of Modern DMT Research: https://youtu.be/KeAZOj7tYscAndrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDAGUEST LINKSX: https://x.com/Alxdr_BatthyanyGoogle Scholar: https://scholar.google.com/citations?user=VRL8CPYAAAAJPersonal Site: https://sites.google.com/view/alexanderbatthyany/startViktor Frankl Institute Vienna: https://www.viktorfrankl.org/Threshold (2023): https://us.macmillan.com/books/9781250782298/threshold/Psychology Today - Magic Mushrooms and Terminal Lucidity: https://www.psychologytoday.com/us/blog/consciousness-and-meaning-at-lifes-end/202607/magic-mushrooms-and-terminal-lucidityBatthyany & Greyson (2021), Spontaneous Remission of Dementia Before Death: https://med.virginia.edu/perceptual-studies/wp-content/uploads/sites/360/2021/04/terminal-lucidity-PC.pdfSKOOLWant a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/aboutFOLLOW EVANhttps://x.com/evan_mcglTIMESTAMPS0:00:00 Trailer0:02:29 What Terminal Lucidity Actually Is0:05:33 Why He'd Rather Call It "Paradoxical Lucidity"0:06:01 "Call Your Grandma - She's Back Again"0:09:11 The Victorians Documented It, Then Medicine Stopped0:10:55 "We Saw It, But We Didn't Write It Down"0:12:58 Frankl's Rule: Treat Them As Fully Present0:17:35 What Brain Age Was She Speaking From?0:18:36 "It Was All As If In A Fog"0:21:11 The Wife Who Filmed It So People Would Believe Her0:25:40 The Art Historian Who Gave Back His Books0:30:27 Is It Comforting For Families, Or Crueller?0:32:02 The Three Shocks Every Family Goes Through0:38:05 450 Cases And Counting0:41:29 Does It Have Anything To Do With Death At All?0:45:12 Steven Pinker: "You're Seeing Figures In Clouds"0:47:10 "Everywhere And Nowhere"0:49:47 They Overdosed Her On Psilocybin. She Woke Up.0:51:37 She Got Her Sense Of Humour Back0:55:18 Dresden: The Brain Hadn't Changed At All0:56:37 "Some Of Our Personhood Is Platform Independent"1:02:40 Near-Death Experiences vs Paradoxical Lucidity1:05:52 Rick Strassman, DMT And Neuroprotection1:11:22 "How Can We Get Them Out?"1:20:20 When Vienna Gave Psychiatric Patients Malaria.....Email for sponsorship enquiries: evan@thegiantsshoulder.com

  4. 7 set

    #153 - Meet The Neuroscientist Who Does Recreational Heroin

    🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/join Carl Hart is a human drug scientist — the Mamie Phipps Clark Professor of Psychology in Psychiatry at Columbia University and Chair of its Department of Psychology, who runs one of the very few laboratories on earth licensed to give people real doses of crack cocaine, methamphetamine and MDMA. His volunteers live inside a sealed four-room lab for weeks at a time, originally built for NASA to study astronauts, with no contact with the outside world while he measures their sleep, their food intake and how much they speak. He started that work believing drugs were what had gone wrong in neighbourhoods like the one he grew up in. Thirty years of data refused to agree with him. Expect to learn why there is no such thing as drug addiction in a rat, why "hard drugs" is a category the human body doesn't recognise, why he refuses to use the word "psychedelic", how one extra methyl group is the only difference between methamphetamine and the main ingredient in Adderall, why psychiatry still runs on a theory formalised in 1967 when only six neurotransmitters were known, what heroin actually feels like and why the real danger is constipation rather than overdose, why addiction tracks access rather than pharmacology, and much more… SPONSORS Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulder GS EPISODES MENTIONED David Luke - Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://youtu.be/qLKD1gt1X5o GUEST LINKS Columbia Psychiatry Profile: https://www.columbiapsychiatry.org/profile/carl-hart-phd Personal Website: https://drcarlhart.com/ X: https://x.com/drcarlhart Drug Use for Grown-Ups: Chasing Liberty in the Land of Fear: https://en.wikipedia.org/wiki/Drug_Use_for_Grown-Ups High Price: A Neuroscientist's Journey of Self-Discovery: https://en.wikipedia.org/wiki/High_Price_(book) FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:16 Why Human Rights Became His Whole Mission 0:03:45 "I Believed the Bullshit About Drugs" 0:07:42 The Brain-Imaging Studies That Prove Nothing 0:10:32 Why "Hard Drugs" Is a Made-Up Category 0:12:42 There Is No Such Thing as Addiction in a Rat 0:14:18 Put Cocaine on Your Gum and See What Happens 0:15:50 Rat Models for Autism, ADHD and Depression 0:18:03 How Many Hoops to Give a Human Crack Cocaine 0:20:38 "Psychedelic" Is a Political Word, Not a Real Thing 0:22:40 Why the One-Receptor Story Is Bullshit 0:23:56 Psychiatry Is Still Running on a 1967 Theory 0:31:17 One Methyl Group: Meth vs Adderall 0:34:41 The Lab NASA Built for Astronauts 0:37:45 The Phenomenology Gap Nobody Studies 0:39:01 "I Was a Virgin to These Drugs, And Not Even Curious" 0:44:14 What Heroin Actually Feels Like 0:47:04 The Real Danger Is Constipation 0:52:47 The Overdose Myth He's Trying to Destroy 0:55:39 Education, Not Harm Reduction 0:58:40 Addiction Isn't About Drugs, It's About Access 1:01:38 Not Whether to Legalise, But How 1:05:30 Dublin's Cocaine Problem, Evan Pushes Back 1:06:46 "That's Quite Arrogant of You" 1:09:05 The Same Argument That Delayed Emancipation 1:12:50 "We Put People on the Moon. This Is Not Complicated." .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

  5. 3 set

    #152 - Meet The Biophysicist Who Accidentally Discovered Telepathy

    JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing👇 https://www.youtube.com/@thegiantsshoulder/join Luca Turin is a biophysicist who has spent thirty years arguing that the nose reads a molecule's vibrations rather than its shape, published in Nature at twenty-three, and co-wrote the definitive critical guide to perfume with his wife Tania Sanchez. The vibrational theory of olfaction was declared dead twice before he revived it, and he is still waiting for the one experiment that would settle it. His newest result has nothing to do with smell: fruit flies sealed in separate opaque wells, with no sight, sound or scent between them, coordinate their movement anyway — and the coordination vanishes the moment the plate is made of metal. This is a scientist who went looking for anaesthesia and found something that looks like insect telepathy. Expect to learn why creating a smell stimulus is nothing like creating a colour, how a startup elicited smell sensations with ultrasound for the first time in history, why the only two chemical groups in the universe that share one vibration are also the only two that smell of rotten eggs, how a receptor could read vibrations with no lenses or prisms anywhere in your nose, why the famous "trillion smells" figure was a mathematical error, why nobody in pharmacology can predict what a drug will do once it binds, how Google Quantum AI's xenon question led to fruit flies, what happened when the plates were swapped for aluminium, why radio frequency would be the perfect brain-wide reward signal, and much more… SPONSORS Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial - https://app.macrofactor.com/mfgiants GS EPISODES MENTIONED Earl K Miller - Meet the MIT Neuroscientist Showing Brain Waves Are the Secret Engine Behind Consciousness: https://youtu.be/7OFb-NG3jIw Marjorie Woollacott - Neuroscientist: "Your Brain Doesn't Create Consciousness" — NDEs, Telepathy and Terminal Lucidity: https://youtu.be/mDWtmfmIUHA GUEST LINKS Google Scholar: https://scholar.google.com/citations?user=fgXXdQYAAAAJ Wi-Fly Project: https://wi-fly.eu/ X: https://x.com/LucaTurin Substack: https://lucaturin.substack.com YouTube: https://www.youtube.com/@lucaturin SKOOL Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:20 Biophysicists Are Dreamers, Biologists Are Doomed 0:07:07 The Startup That Triggered Smells With Ultrasound 0:12:22 The Rotten-Egg Coincidence That Convinced Him 0:18:34 What The Receptor Is Actually Reading 0:19:54 Electron Tunnelling, Explained Simply 0:23:33 The Trillion-Smells Figure Was A Maths Error 0:28:21 What Perfumers Perceive That You Don't 0:32:14 Why Every Drug Receptor Might Be Electrical 0:33:12 The Mystery Nobody Admits: Drug Efficacy 0:39:28 "Cascade" Is A Word That Masks Ignorance 0:44:04 The Receptor As A Transistor 0:48:40 Google Quantum AI And The Xenon Puzzle 0:52:24 Two Years Of Work, A Definite Maybe 0:53:55 30 Flies Freeze Like The Guards At Buckingham Palace 0:55:28 One Fly Per Well, No Way To Communicate 0:56:17 To My Total Astonishment, They Coordinate 0:58:45 Metal Plates Kill The Signal 0:59:36 The Wi-Fly: A Radio Network For Flies 1:11:26 Radical Pairs: How A Fly Could Listen 1:16:34 What Is The Brain's Reward Signal? 1:19:59 Standing Waves And The Binding Problem 1:23:58 Could Humans Ever Do This? 1:27:46 Ramanujan And Latent Abilities 1:36:16 Giving Fruit Flies DMT .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

  6. 31 ago

    #151 - Meet the Greatest Lucid Dreaming Scientist You've Never Heard Of

    🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/join Karen Konkoly is a dream scientist who led the first study to hold a real-time, two-way conversation with a person inside a dream, putting maths problems to sleepers in REM and getting answers back through their eye movements. She is a Marie Curie Postdoctoral Fellow in the Cambridge Consciousness and Cognition Laboratory, completed her PhD in the Paller Cognitive Neuroscience Laboratory at Northwestern University, and has spent her career building tools to engineer dreams — from targeted lucidity reactivation for narcolepsy nightmares to planting unsolved problems into REM sleep. She has also asked a dream character to swap bodies with her, and woken up inside it. This is the strangest conversation we have had on the channel. Expect to learn how scientists prove someone is awake inside a dream, why you still cannot fly in your own dream even when you know it is a dream, what happened when Karen swapped bodies with a dream character, whether time really slows down while you sleep, why practising darts in a lucid dream works about as well as practising awake, what galantamine and acetylcholine actually do to REM sleep, the exact protocol for having your first lucid dream, why Karen no longer believes lucidity is the key to consciousness, and much more… SPONSORS Get One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqe GS EPISODES MENTIONED David Spiegel - World's Greatest Hypnosis Scientist Hijacks My Mind Live On Camera!: https://youtu.be/eCtRBZHIsgQ GUEST LINKS Personal Website: https://www.karenkonkoly.com/ Google Scholar: https://scholar.google.com/citations?user=teYHEFIAAAAJ&hl=en Cambridge Consciousness & Cognition Lab: https://www.ccc-lab.org/ Dust Systems (Dream Engineering): https://www.dust.systems/people/karen-konkoly X: https://x.com/KarenKonkoly LISTEN ON Spotify - https://open.spotify.com/show/5m3Gta5MtIYdk59pb2GJ7M Apple - https://podcasts.apple.com/ie/podcast/the-giants-shoulder/id1752486249 SKOOL Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:03:18 What Lucid Dreaming Actually Is 0:05:37 Wake Back To Bed: The 4am Method 0:06:40 Why You Still Can't Fly In Your Own Dream 0:09:20 How You Prove Someone Is Lucid In A Dream 0:11:53 Are The Sleep Stages Even Real? 0:15:28 When A Dream Dissolves But You Don't Wake Up 0:19:19 The Reality Check You Can Do Tonight 0:21:00 Does Time Run Slower Inside A Dream? 0:24:45 Trying And Failing To Become Her Dog 0:26:10 Swapping Bodies With A Dream Character 0:27:51 Is Lucidity A Glitch In Consciousness? 0:33:37 Hyperphantasia And Maladaptive Daydreaming 0:37:53 Practising Darts While You're Asleep 0:41:52 When Lucid Dreaming Is A Bad Idea 0:46:09 Why A Giraffe Can't Appear While You're Awake 0:49:54 Galantamine, Acetylcholine And Dream Drugs 0:52:17 The Squat Experiment 0:58:38 The Full Protocol, Step By Step 1:04:55 What This Teaches Us About Consciousness 1:09:15 Who Are Your Dream Characters? 1:12:55 "You're Not You" 1:14:41 Hypnosis, David Spiegel And Lucid Dreaming 1:18:20 What She's Working On Next .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

  7. 27 ago

    #150 - World's Greatest Hypnosis Scientist Hijacks My Mind Live On Camera!

    🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing 👇 https://www.youtube.com/@thegiantsshoulder/join David Spiegel is the world's leading hypnosis scientist — fifty years at Stanford spent proving that trance is a measurable brain state rather than a stage trick, across thirteen books, four hundred papers and roughly seven thousand patients hypnotised personally. I told him to his face that I thought his entire field was a scam, so he ran the hypnotisability test on me live on camera, my left arm floated off the desk and stopped obeying me for the next forty minutes, and he scored me seven out of ten. Expect to learn what hypnosis actually is and the three components it breaks down into, how stage hypnotists secretly screen their audiences before the show even starts, what changes in three separate brain networks the moment you go under, why "suggestibility" is the wrong word and cognitive flexibility is the right one, how hypnotised subjects cut their brain's electrical response to pain by 50%, why one in four smokers quit after a single session, the two very different childhoods that both produce highly hypnotisable adults, why eight-year-olds are the most hypnotisable people alive, how Rory McIlroy used self-hypnosis to break a seven-year Masters curse, what it feels like to have your own arm stop belonging to you, and much more… SPONSORS Try Reveri, Dr David Spiegel's Self-Hypnosis App (use code SPIEGEL20 for your discount) - https://reverihealth.app.link/e/spiegel Get One Month Free of Consensus (The Best Ai Science Tool) - https://get.consensus.app/we00d2cmjpqe GUEST LINKS Stanford Profile: https://profiles.stanford.edu/david-spiegel Reveri: https://www.reveri.com/ Reveri on X: https://x.com/reveri_health Stanford Center on Stress and Health: https://med.stanford.edu/stresshealthcenter.html Trance and Treatment (his clinical textbook): https://www.appi.org/Products/Hypnosis/Trance-and-Treatment-Second-Edition SKOOL Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about FOLLOW EVAN https://x.com/evan_mcgl TIMESTAMPS 0:00:00 Trailer 0:02:27 Who Is David Spiegel? 0:03:39 What Hypnosis Actually Is 0:05:37 Why He Calls Stage Shows "Dumb Shows" 0:06:29 How Hypnotists Secretly Screen The Audience 0:09:08 The Student Who Relived Being A Newborn 0:10:46 What Hypnosis Does To Three Brain Networks 0:13:23 It's Not Suggestibility, It's Cognitive Flexibility 0:16:12 Cutting The Brain's Pain Signal By 50% 0:17:05 One In Four Quit Smoking In A Single Session 0:18:33 The Meditator Whose Migraines Vanished 0:22:36 Why Hypnotisability Is Partly Genetic 0:23:54 The Two Childhoods That Make You Hypnotisable 0:27:16 Hypnosis, Flow States And Peak Performance 0:32:54 How Rory McIlroy Broke His Masters Curse 0:38:05 Why You Can Forget Your Own Name 0:44:29 Filtering The Hurt Out Of Pain 0:55:00 The Hypnotisability Test, Live On Camera 1:00:15 "It's Actually Going Up" 1:08:52 Evan Scores 7 Out Of 10 1:18:42 Trying To Erase The Number Four 1:31:04 "Please Don't Do This On My Other Arm" .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

  8. 24 ago

    #149 - Meet The Father Of Modern DMT Research

    🧠 JOIN THE GIANT'S SHOULDER FAMILY Become a YouTube Member for exclusive episodes, early access + ad-free viewing: https://www.youtube.com/@thegiantsshoulder/join Rick Strassman is the psychiatrist who ran the first new American psychedelic research in a generation — five years of DMT studies at the University of New Mexico, the first rating scale ever built specifically to measure a psychedelic experience, and the book that made DMT famous. DMT: The Spirit Molecule sold a quarter of a million copies and effectively created machine-elf culture. Thirty years on, he is the most sceptical man in the room about what those entities actually are. Expect to learn why your brain spends energy importing DMT across the blood-brain barrier, why the pineal gland story he made famous fell apart, how brain DMT sits at the same concentration as serotonin and dopamine, why DMT floods the visual cortex of a dying brain, why a molecule that shrinks strokes and protects kidneys should not be psychedelic at all, what the endomatrix is and why it raises the simulation question, why he now thinks psychedelics are super placebos, what a DMT entity actually is and why talking to one is like talking to an AI, how you would actually test whether the entities are real, why only one scientist on Earth is studying endogenous DMT, and much more… SPONSORS Get Jenni Your Intelligent Research Assistant (GIANT20 for 20% off) - http://jenni.ai/?utm_source=youtube&utm_medium=inf&utm_campaign=thegiantsshoulder Join the Outskill AI Mastery Sprint (Free This Weekend) - https://links.outskill.com/GIASHOULAUG2 GS EPISODES MENTIONED Steven Barker - Meet The World's Greatest Endogenous DMT Psychedelic Scientist You've Never Heard Of: https://youtu.be/gTc5QjyZuvY David Luke - Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://youtu.be/qLKD1gt1X5o Deborah Mash - Meet The Ibogaine Psychedelic Scientist Who First Unravelled Its Big Mystery: https://youtu.be/z7eRtXV6ptA Robin Carhart-Harris - No. 1 Psychedelic Scientist: The Entropic Brain Hypothesis, Consciousness & DMT Entities: https://youtu.be/t-GkE4YtLRk Andrew Gallimore - No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://youtu.be/USgWrxEFWDA GUEST LINKS Official Site: https://www.rickstrassman.com/ Books & Publications: https://www.rickstrassman.com/publications/ Substack: https://rickstrassman.substack.com/ YouTube: https://youtube.com/c/RickStrassman Biosynthesis and Extracellular Concentrations of DMT in Mammalian Brain (Dean et al., Scientific Reports 2019): https://www.nature.com/articles/s41598-019-45812-w TIMESTAMPS 0:00:00 Trailer 0:04:31 The First Legal DMT Studies in a Generation 0:07:41 The Bomb-Maker Who Became a Psychedelic Scientist 0:14:13 The Iron Curtain Reason We Know DMT Works 0:22:32 Why Your Brain Spends Energy Importing DMT 0:28:26 Your Brain Makes DMT at Serotonin Levels 0:29:26 DMT Floods the Dying Brain's Visual Cortex 0:30:28 Stroke, Kidneys and Heart — DMT as a Survival Molecule 0:32:39 The $64,000 Question Nobody Can Answer 0:36:33 Does DMT Regulate How Real Reality Feels? 0:39:32 Only One Person on Earth Studies This 0:43:52 The Endomatrix and the Simulation Question 0:49:48 "Psychedelics Are Super Placebos" 0:55:12 The Man Who Wrote Down "Bananas Are Really Yellow" 1:03:50 The Barking Patient — Entities as Dream Logic 1:05:42 Talking to Entities Is Like Talking to an AI 1:06:40 The Prime Number Test for Proving Entities Are Real 1:13:36 Half His Volunteers Met Beings — And a Conscious Apartment 1:18:08 "Your Brain On Drugs" vs Another Dimension 1:26:58 The Entities That Curse You 1:29:09 "Have You Started Yet?" — The Man Immune to DMT 1:33:30 Why DMT Is the Only Psychedelic Without Tolerance 1:36:12 Blocking 5-HT1A Tripled the Effect — Buried 30 Years 1:39:06 Aphantasia and Seeing For the First Time .....Email for sponsorship enquiries: evan@thegiantsshoulder.com

Descrizione

A Biology & Consciousness podcast chronicling the bio-singularity. 3x times per week I speak with leading scientists at the bleeding edge of Neuroscience, Consciousness and Biology. No idea is too strange, tackled with genuine curiosity and technical rigour. Come follow the journey as I have my brain melted and ontology warped on a regular basis. Evan has a Neuroscience degree from Trinity College Dublin and is founder of Giants Shoulder.

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