144 episodi
Metabolism Made Easy A J Ghalayini, Ph.D.
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- Istruzione
This podcast describes selected biochemistry content that could be useful to premedical/medical students.
Similar content (podcasts and videos) is available at:
https://medbiochem.org/
or check out my YouTube channel: Metabolism Made Easy
These podcasts and videos cover selected topics in medical biochemistry.
A J Ghalayini, Ph.D.
Bio for Dr. Ghalayini:
Dr. Ghalayini received his Ph.D. in Biochemistry from the University of Houston, Houston, Texas. He has over 3 decades of experience in research and medical education as professor of biochemistry at 5 different universities.
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Hormonal Regulation of Metabolism in a Nutshell
This podcast covers 4 distinct classes of receptors and their respective hormones, including the mechanism of transducing their intracellular signals. The receptors covered in detail are the steroid receptor, the insulin receptor, and 3 distinct G-protein coupled receptors, including the second messengers they produce.
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The Brain's Energy Sources
This podcast covers the use of glucose and ketone bodies as energy sources by the brain. During sleep and short fasts, the brain is completely dependent on the output of glucose by the liver. Glucose is oxidized all the way to CO2 by the brain under aerobic conditions to produce up to 38ATPs.
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GLucose Transporters
This podcast covers the tissue distribution of various glucose transporters and their role of glucose uptake from the bloodstream, including the regulation of one transporter (Glut-4) by insulin.
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The Purine Salvage Pathway
This podcast covers the salvage of Hypoxanthine, guanine and adenine by two important enzymes Hypoxanthine-guanine phosphoribosyl transferase (HGPRT) and Adeneine phosphoribosyl transferase (APRT), including the outcome of an inherited deficiency in HGPRT.
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Glucose Uptake by Muscle & Adipose Tissue
This podcast covers the insulin-dependent uptake of glucose by GLUT-4 in muscle and adipose tissue. This insulin-dependent uptake by these tissues contributes to the reduction of plasma glucose after a meal.
Check out the link below for the video podcast:
https://youtu.be/_vyijJKL4oY
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Glucose: The Essential Nutrient
This podcast covers the essential role of glucose as an energy source for several tissues. Most notably, red blood cells and the brain. Red blood cells are entirely dependent on glucose for their energy needs while the brain is highly dependent on glucose for its energy. Glucose in the bloodstream is produced by the liver and maintained around 80-100mg/dl during fasting to provide red blood cells and the brain with their energy needs.
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Send in a voice message: https://podcasters.spotify.com/pod/show/a-j-ghalayini/message