にゃんごう＆いがさんのEBMerな‪夜‬ Yeishu Nyango

にゃんごう＆いがさんのEBMerな夜

第69回放送　2022/8/31



【にゃんごう：HFpEFに対するSGLT2阻害薬】

Solomon SD, McMurray JJV, Claggett B, de Boer RA, DeMets D, Hernandez AF, Inzucchi SE, Kosiborod MN, Lam CSP, Martinez F, Shah SJ, Desai AS, Jhund PS, Belohlavek J, Chiang CE, Borleffs CJW, Comin-Colet J, Dobreanu D, Drozdz J, Fang JC, Alcocer-Gamba MA, Al Habeeb W, Han Y, Cabrera Honorio JW, Janssens SP, Katova T, Kitakaze M, Merkely B, O'Meara E, Saraiva JFK, Tereshchenko SN, Thierer J, Vaduganathan M, Vardeny O, Verma S, Pham VN, Wilderang U, Zaozerska N, Bachus E, Lindholm D, Petersson M, Langkilde AM; DELIVER Trial Committees and Investigators.

Dapagliflozin in Heart Failure with Mildly Reduced or Preserved Ejection Fraction.

N Engl J Med. 2022 Aug 27. doi: 10.1056/NEJMoa2206286. Epub ahead of print.

PMID: 36027570.

https://www.nejm.org/doi/10.1056/NEJMoa2206286



【いがさん：発熱患者の解熱治療】

Holgersson J, Ceric A, Sethi N, Nielsen N, Jakobsen JC.

Fever therapy in febrile adults: systematic review with meta-analyses and trial sequential analyses.

BMJ. 2022 Jul 12;378:e069620. doi: 10.1136/bmj-2021-069620.

PMID: 35820685; PMCID: PMC9274300.

https://www.bmj.com/content/378/bmj-2021-069620.long



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にゃんごうの解説で紹介したメタアナリシスの論文．

Vaduganathan M, Docherty KF, Claggett BL, Jhund PS, de Boer RA, Hernandez AF, Inzucchi SE, Kosiborod MN, Lam CSP, Martinez F, Shah SJ, Desai AS, McMurray JJV, Solomon SD.

SGLT-2 inhibitors in patients with heart failure: a comprehensive meta-analysis of five randomised controlled trials.

Lancet. 2022 Aug 26:S0140-6736(22)01429-5. doi: 10.1016/S0140-6736(22)01429-5. Epub ahead of print.

PMID: 36041474.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01429-5/fulltext

にゃんごう＆いがさんのEBMerな夜

第68回放送　2022/7/31



【にゃんごう：PPI不適切処方】

Koggel L, Lantinga M, Buchner F, Drenth J, Frankema J, Heeregrave E, Heringa M, Numan, M, Siersema P.

Predictors for inappropriate proton pump inhibitor use: observational study in primary care.

Br J Gen Pract. 2022 June 20. doi: 10.3399/BJGP.2022.0178

https://bjgp.org/content/early/2022/06/24/BJGP.2022.0178



【いがさん：コロナワクチン不接種理由】

Nomura S, Eguchi A, Yoneoka D, Murakami M, Ghaznavi C, Gilmour S, Kaneko S, Kawashima T, Kunishima H, Naito W, Sakamoto H, Maruyama-Sakurai K, Takahashi A, Takayama Y, Tanoue Y, Yamamoto Y, Yasutaka T, Miyata H.

Characterising reasons for reversals of COVID-19 vaccination hesitancy among Japanese people: One-year follow-up survey.

Lancet Reg Health West Pac. 2022 Jul 21:100541. doi: 10.1016/j.lanwpc.2022.100541. Epub ahead of print.

PMID: 35892010; PMCID: PMC9302916.

https://www.thelancet.com/journals/lanwpc/article/PIIS2666-6065(22)00156-0/fulltext



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にゃんごう＆いがさんのEBMerな夜

第67回放送　2022/6/29



【いがさん：帝王切開で生まれた子どもに対する切開前と臍帯締付後の予防的抗菌薬使用の長期的影響】

?umilo D, Nirantharakumar K, Willis BH, Rudge G, Martin J, Gokhale K, Thayakaran R, Adderley NJ, Chandan JS, Okoth K, Hewston R, Skrybant M, Deeks JJ, Brocklehurst P.

Long-term impact of giving antibiotics before skin incision versus after cord clamping on children born by caesarean section: protocol for a longitudinal study based on UK electronic health records.

BMJ Open. 2019 Sep 26;9(9):e033013. doi: 10.1136/bmjopen-2019-033013.

PMID: 31558464; PMCID: PMC6773283.

https://www.bmj.com/content/377/bmj-2021-069704



【にゃんごう：費用対効果分析におけるスポンサーシップバイアス】

Xie F, Zhou T.

Industry sponsorship bias in cost effectiveness analysis: registry based analysis.

BMJ. 2022 Jun 22;377:e069573. doi: 10.1136/bmj-2021-069573.

PMID: 35732297.

https://www.bmj.com/content/377/bmj-2021-069573



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にゃんごう＆いがさんのEBMerな夜

第66回放送　2022/5/31



第13回日本プライマリ・ケア連合学会学術大会

2022年6月11日（土）～12日（日）

パシフィコ横浜

https://jpca2022.org/



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にゃんごう＆いがさんのEBMerな夜

第65回放送　2022/4/24



【にゃんごう：アルツハイマー型認知症予防のためのライフスタイル】

Dhana K, Franco OH, Ritz EM, Ford CN, Desai P, Krueger KR, Holland TM, Dhana A, Liu X, Aggarwal NT, Evans DA, Rajan KB.

Healthy lifestyle and life expectancy with and without Alzheimer's dementia: population based cohort study.

BMJ. 2022 Apr 13;377:e068390. doi: 10.1136/bmj-2021-068390.

PMID: 35418416.

https://www.bmj.com/content/377/bmj-2021-068390



【いがさん：尿路感染症に対するテビペネム・ピボキシル臭化水素酸塩】

Eckburg PB, Muir L, Critchley IA, Walpole S, Kwak H, Phelan AM, Moore G, Jain A, Keutzer T, Dane A, Melnick D, Talley AK.

Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection.

N Engl J Med. 2022 Apr 7;386(14):1327-1338. doi: 10.1056/NEJMoa2105462.

PMID: 35388666.

https://www.nejm.org/doi/full/10.1056/NEJMoa2105462



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にゃんごう＆いがさんのEBMerな夜

第64回放送　2022/4/3



【にゃんごう：ACE阻害薬による肺炎予防】

Tsunoda, H, Okami, Y, Honda, Y, Shiroshita, A, Kataoka, Y, Tsujimoto, Y, et al. Effectiveness of angiotensin converting enzyme inhibitors in preventing pneumonia: A systematic review and meta-analysis. J Gen Fam Med. 2022; 00: 1-11.

https://onlinelibrary.wiley.com/doi/10.1002/jgf2.532



【いがさん：尿路感染予防のための馬尿酸メテナミン】

Harding C, Mossop H, Homer T, Chadwick T, King W, Carnell S, Lecouturier J, Abouhajar A, Vale L, Watson G, Forbes R, Currer S, Pickard R, Eardley I, Pearce I, Thiruchelvam N, Guerrero K, Walton K, Hussain Z, Lazarowicz H, Ali A. Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial. BMJ. 2022 Mar 9;376:e068229. doi: 10.1136/bmj-2021-0068229. PMID: 35264408; PMCID: PMC8905684.

https://www.bmj.com/content/376/bmj-2021-0068229



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