Bloody Minded

Bloody Minded Crew
  • 0.0（0）
  • 医学
  • アップデート：毎週

Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the fellows of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs.  Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au

  1. 2日前

    Episode 96 - On the Ning Nang Nongs | B12 and Folate Metabolism

    On the Ning Nang Nongs where the youths smoke bongs and the marrow all screams HELP! Join the Bloody Minded crew as they go through the round window, follow B12 and folate around the body in a Nang induced haze, presumably just like the writers on Play School once were.  Mandatory viewing: https://www.youtube.com/watch?v=3SUU1f3Mgpc&list=RD3SUU1f3Mgpc&start_radio=1 TIMESTAMPS 0:53 - A Bloody Minded After School Special 1:50 - Megaloblastic Anaemias 2:59 - An Intro to B12 7:49 - B12 Absorption 12:55 - Role of B12 15:07 - MMA + Homocysteine 16:40 - Causes of B12 Deficiency 20:04 - Nangs - Again 23:18 - Intro to Folate 25:32 - Folate Absorption 27:03 - Folate Deficiency 30:00 - Concurrent B12 + Folate Deficiency 32:18 - Take Home Messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    35分

  2. 6月30日

    Episode 95 - Feeling Rusty? | In The Lab: Iron Studies

    Heal with steel? Absolutely not - There’s no alloys or for that matter surgeons allowed in the safe space of the laboratory. Join us on another wonderful lab adventure as Bashar, Cale and Nick head down to the biochemistry lab to work out exactly how our iron studies are performed in the lab before you throw the serum iron in the bin. TIMESTAMPS 0:53 - An early etymological diversion 2:53 - Serum iron 9:43 - UIBC 11:22 - TIBC 13:34 - Transferrin 15:45 - Transferrin saturation 17:25 - Ferritin 20:42 - Example of how the numbers work 23:31 - The iron stain 25:02 - Take home messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    27分

  3. 6月23日

    Episode 94 - It should be a Fe-lony | Interpeting Iron Studies

    Taunted by transferrin? Befuddled by ferritin? Scratching your head at why we throw the serum iron results directly into the confidential waste bin, which is a more dignified burial than it deserves? Come along as the boys discuss the interpretation of iron studies in a definitely tight, definitely 20ish minute episode. Timestamps 00:54 - Just Iron Studies with No Nonsense 02:21 - Overview of Iron Stuides 03:42 - Serum Iron 05:35 - Transferrin 07:32 - TIBC 08:35 - UIBC 10:47 - Transferrin Saturation (TSat) 12:38 - Ferritin 14:34 - Soluble Transferrin Receptor (sTfR) 15:45 - Invasive Iron Studies 16:52 - Rapid Fire Case Studies ft. Geraldine 22:25 - Summary & Take Home Messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    25分

  4. 6月16日

    Episode 93 - The Silmaril-IRON | Iron Metabolism

    One molecule to rule them all, one molecule to find them. One molecule to bring them all, and in the liver bind them. Hepcidin is the key to understanding iron metabolism and we examine how iron gets into, around and out of the body. We promise not to be too Celebrimbor-ing as you join Nick, Cale and Bashar  for this discussion of the basic science of iron handling in preparation for our journey into the building blocks of blood. Welcome to Lord of the Haematinics.  TIMESTAMPS 0:56 - The next arc of the Bloody Minded Cinematic Universe 3:23 - Series overview 6:21 - Basic iron metabolism 7:54 - The three main player groups in iron metabolism 8:44 - Iron binding molecules: Heme 13:22 - Non-heme iron 14:05 - Iron binding molecules: Ferritin 17:12 - Iron binding molecules: Transferrin 20:44 - Iron transporters: DMT1 25:02 - Iron transporters: ferroportin 28:21 - Iron transporters: Hephaestin 29:28 - Iron flux 33:24 - Hepcidin: Master Regulator and The One Ring 39:04 - Non-hepcidin regulation of Ferroportin and IREs 41:32 - Take home messages Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    44分

  5. 6月2日

    Episode 92 - On The Wards: A Practical Guide To Anticoagulants | Part 3 (Fancy Anticoagulants)

    Has your ward team been hit with HITT? Is Jane the only Fonda you know? Is BAD an 80s hit and not a trio of anti-coagulation infusions (Bivalirudin, Argatroban and Danaparoid). Is Alison showing her age? Never fear; join Alison, Bashar, Nick and Cale as they aim to de-mystify less commonly used anticoagulation that may come up on the wards.  TIMESTAMPS 0:56 - It's Fancypants Wednesday! 2:15 - Episode overview 4:37 - Fondaparinux 9:07 - When to use fonda 12:35 - Argatroban 17:25 - When to use argatroban 18:02 - Bivalirudin 19:11 - Mandatory historical diversion 22:50 - Back to bivali business 25:59 - Danaparoid 30:21 - When to use danaparoid 32:45 - Quick summary 34:13 - Dalteparin 38:02 - A bit of nonsense chitchat Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    40分

  6. 5月19日

    Episode 91 - Have you tried turning it off and on again? | Allogeneic transplant in AML with Prof John Moore

    Join us in our third straight week of incredibly nice and incredibly talented haematology gurus as Professor John Moore joins us as an expert guest to discuss stem cell transplant in the myeloid disease setting.  TIMESTAMPS  1:00 – HYTTIOAOA  1:47 – Introducing Professor John Moore  8:06 – Advice to RMOs on the Allo Term  11:02 – The history of allogeneic transplantation  18:26 – Modern morbidity/mortality from alloSCT for AML  23:05 – Use of transplant scoring systems  27:29 – The role of MRD in transplant decisions  30:04 – MAC vs. RIC – Choice of Conditioning  38:15 – The role of PTCy  40:17 – Second allogeneic transplants  42:02 – DLI  43:08 – Biallelic TP53 – no good options  45:29 – Free rein in the trials space  49:11 – AlloSCT/CAR-T for autoimmune disease  55:05 – Take Home Messages  Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    57分

  7. 5月12日

    Episode 90 - GENEsis | In the Lab: NGS in AML with Dr Michael Krigstein

    This week we continue the pattern of guests who are really really ridiculously good at haematology and also really really ridiculously nice people as well. We are very excited to be joined by Dr Michael Krigstein who many of you would know as the a molecular haematology guru who has gotten countless patients through their diagnoses and countless haematology trainees through their exams. Timestamps: 01:30 - Introducing Dr Michael Krigstein 04:23 - Getting into Lab Haem 08:30 - The Mechanics of NGS 16:57 - Learning to report - RCPA Modules 19:58 - After the NGS - Curation 24:14 - NGS - Not a panacea 28:45 - Why NGS is bad at ITDs 32:42 - Panel Design 36:37 - RNA vs DNA Panels 39:16 - The future of NGS in haematology 46:56 - A standout case 53:36 - Wrapup Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    55分

  8. 5月5日

    Episode 89 - What is this, disease for ants? | MRD in AML with Dr Jad Othman

    What happens when you take someone who is really really ridiculously good at haematology and also a really really ridiculously nice person as well? You get Dr Jad Othman, consultant Haematologist and Haematopathologist at Royal North Shore Hospital in Sydney who will be joining us today to discuss the use of measurable residual disease in acute myeloid leukaemia. Dr Othman is well suited to this topic, having written his doctoral thesis on molecular disease assessment in AML, sitting on the European LeukaemiaNet (ELN)-DAVID MRD Working Group as well as numerous ALLG AML and MDS working groups. We're delighted to have him field the Bloody Minded Crew's questions today.  Timestamps 01:00 - The boys making outdated millenial references 02:50 - Getting to know Dr Jad Othman 09:50 - The concept of MRD 11:55 - Lab techniques for MRD 17:59 - Why doesn't everyone have an MRD marker? 20:51 - What makes a good MRD assay? 24:14 - Patients without a molecular MRD marker 26:21 - Clinical case 30:30 - What we do with MRD results 31:47 - The NPM1/FLT3 PB/BM situation 35:31 - Why MRD is actually helpful 39:40 - Why single agent treatment in AML is challenging 44:33 - The 2025 ELN DAVID update 48:44 - Does doing MRD improve OS? 52:21 - The INTERCEPT study 55:41 - Wrap up and summary Support the show Check out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

    59分
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予告編

番組について

Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the fellows of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs.  Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au

情報

  • クリエイター
    Bloody Minded Crew
  • 配信期間
    24年 - 26年
  • エピソード
    97
  • 制限指定
    不適切な内容を含む
  • Copyright
    © 2026 Bloody Minded
  • 番組のWebサイト
    Bloody Minded

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