This Week in Neuroscience Vincent Racaniello

TWiN reviews experiments which show that SARS-CoV-2 triggers the up-regulation of synaptic components and perturbs local electrical field potential in cerebral organoids, organotypic culture of human brain explants and post-mortem brain samples from individuals with COVID-19. 
Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison
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Links for this episode MicrobeTV Discord Server SARS-CoV-2 perturbs synaptic homeostasis (Nature Micro) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
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TWiN welcomes mice to the elite club of ‘self-aware’ animals, with a study demonstrating a mirror-induced self-directed behavior in mice resembling visual self-recognition. 
Hosts: Vincent Racaniello, Timothy Cheung, and Vivianne Morrison
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Links for this episode MicrobeTV Discord Server Mice are self-aware (Neuron) Mirror self-recognition in mice (Neuron) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv

TWiN describes a study that reveals activation of endogenous retroviruses in oligodenroglia from patients with traumatic brain injury. 
Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung
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Links for this episode MicrobeTV Discord Server Activation of endogenous retroviruses in TBI oligodendroglia (Cell Rep) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv

TWiN explains an amazing study of a man who was paralyzed after a spinal cord injury and regained the ability to walk after implantation of a brain-spinal cord interface. 
Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung
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Links for this episode MicrobeTV Discord Server Walking naturally after spinal cord injury (Nature) The paralyzed rat that walked (YouTube) Mike the headless chicken (Wikipedia) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv

TWiN explains research showing that interaction between glioma cells and neurons in the brain shares mechanistic features with synaptic plasticity that contributes to memory and learning in the healthy brain. 
Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung
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Links for this episode MicrobeTV Discord Server Glioma synapses recruit mechanisms of adaptive plasticity (Nature) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv

TWiN discusses research showing that sciatic nerve activation with electroacupuncture at the sciatic nerve controls systemic inflammation and rescues mice from polymicrobial peritonitis, by inducing vagal activation of aromatic L-amino acid decarboxylase, leading to the production of dopamine in the adrenal medulla. 
Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung
Subscribe (free): Apple Podcasts, Google Podcasts, RSS
Links for this episode MicrobeTV Discord Server Electroacupuncture modulates the immune system (Nat Med) Electroacupuncture drives the vagal–adrenal axis (Nature) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv