AI + a16z

a16z

Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.

  1. 6 HR AGO

    From Vector Databases to Knowledge Engines: The Next Layer of AI

    Peter Levine speaks with Ash Ashutosh, CEO of Pinecone, about the launch of Nexus and the shift from vector databases to knowledge engines. As agents become the primary users of software, they discuss why traditional retrieval systems break down and how AI systems need to evolve to support machine-to-machine interactions. The conversation explores how agents currently spend most of their time retrieving and reasoning over data, why that approach is inefficient, and how moving reasoning closer to the data can dramatically improve performance, accuracy, and cost. Ash also explains how Pinecone is rethinking the stack for agentic applications, introducing new abstractions, query languages, and developer workflows.   Resources: Follow Ash Ashutosh on X: https://x.com/ashashutosh Follow Peter Levine on LinkedIn: https://www.linkedin.com/in/peter-levine-681386172/   Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    46 min

  2. 28 APR

    Why We Need Continual Learning

    Elena Burger speaks with Malika Aubakirova, partner on the AI infrastructure team at a16z, about why today’s AI systems struggle to learn over time. They discuss the limits of in-context learning, the case for continual learning, and how models may need to evolve from static systems into ones that learn from experience.   Resources: Follow Malika on X: https://x.com/MaikaThoughts Follow Elena on X: https://x.com/VirtualElena Read more on Why We Need Continual Learning: https://a16z.com/why-we-need-continual-learning/ Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    19 min

  3. 21 APR

    The Agent Era: Building Software Beyond Chat with Box CEO Aaron Levie

    Erik Torenberg, Steve Sinofsky, and Martin Casado speak to Aaron Levie, CEO at Box, about what happens to enterprise software when agents become the primary users. They discuss why coding agents succeed where other knowledge work agents struggle, what abstraction layers mean for the workforce, and how data access and systems of record must change in an agent-first world. Follow Aaron Levie on X: https://twitter.com/levie Follow Steve Sinofsky on X: https://twitter.com/stevesi Follow Martin Casado on X: https://twitter.com/martin_casado Follow Erik Torenberg on X: https://twitter.com/eriktorenberg Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    1 hr

  4. 8 APR

    Rethinking Git for the Age of Coding Agents with GitHub Cofounder Scott Chacon

    Matt Bornstein speaks with Scott Chacon, cofounder of GitHub and CEO of GitButler, about why Git's user interface has barely changed since 2005, how GitButler is rethinking version control for both humans and AI agents, and what the "next GitHub" might actually look like. They cover parallel branches, agent-optimized CLI design, the future of code review, and why the best engineers of the future will be the best writers.   Resources: Follow Scott Chacon on X: https://twitter.com/chacon Follow Matt Bornstein on X: https://twitter.com/BornsteinMatt     Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    47 min

  5. 1 APR

    How AI Is Reshaping IT Services from the Inside

    Joe Schmidt speaks with Peter Doyle, CEO of Treeline, about why the $100B managed service provider market is a decade behind modern technology and how Treeline is building a new model that combines human technicians with AI and automation. They discuss the company's growth strategy, why pure play software struggles in services categories, and what the forward deployed engineer trend tells us about AI adoption.   Resources: Follow Peter Doyle on LinkedIn: https://www.linkedin.com/in/peterwdoyle/   Follow Joe Schmidt on X: https://twitter.com/joeschmidtiv Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    34 min

  6. 24 MAR

    Patrick Collison on Stripe’s Early Choices, Smalltalk, and What Comes After Coding

    Michael Truell, CEO of Cursor, sits down with Patrick Collison, CEO of Stripe and an investor in Anysphere, to talk about Collison's history with Smalltalk and Lisp, the MongoDB and Ruby decisions Stripe still lives with 15 years later, why he'd spend even more time on API design if he could do it over, and whether AI is actually showing up in economic productivity data. This episode originally aired on Cursor's podcast. Follow Patrick Collison on X:   https://twitter.com/patrickc Follow Michael Truell on X: https://twitter.com/mntruell Follow Cursor: https://www.youtube.com/@cursor_ai Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    53 min

  7. 19 MAR

    OpenClaw: Why the Internet Isn't Built for AI Agents

    Yoko Li, Guido Appenzeller, and Joel de la Garza discuss OpenClaw, the open source personal AI assistant that's forcing a rethink of how identity, permissions, and security work on the internet. They cover why setting up Gmail integration took seven hours, what happens when an agent asks for domain-wide access to every email in your company, and why consumer websites like DoorDash and Amazon have no incentive to make their services agent-friendly.   Resources: Follow Yoko Li on X:  https://twitter.com/stuffyokodraws Follow Guido Appenzeller on X:  https://twitter.com/appenz Follow Joel de la Garza on LinkedIn:  https://www.linkedin.com/in/3448827723723234/ Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    47 min

  8. 17 MAR

    What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado

    Vishal Misra returns to explain his latest research on how LLMs actually work under the hood. He walks through experiments showing that transformers update their predictions in a precise, mathematically predictable way as they process new information, explains why this still doesn't mean they're conscious, and describes what's actually required for AGI: the ability to keep learning after training and the move from pattern matching to understanding cause and effect.   Resources: Follow Vishal Misra on X: https://x.com/vishalmisra  Follow Martin Casado on X: https://x.com/martin_casado   Check out everything a16z is doing with artificial intelligence here, including articles, projects, and more podcasts.   Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

    48 min
See All (95)

About

Artificial intelligence is changing everything from art to enterprise IT, and a16z is watching all of it with a close eye. This podcast features discussions with leading AI engineers, founders, and experts, as well as our general partners, about where the technology and industry are heading.

Information

  • Creator
    a16z
  • Years Active
    2024 - 2026
  • Episodes
    95
  • Rating
    Explicit
  • Show Website
    AI + a16z

You Might Also Like