In this episode of the AI at Health series on The Beat Podcast, host Sandy Vance sits down with Venky Ananth, Executive Vice President and Head of Healthcare at Infosys, for a wide-ranging and energizing conversation about what it actually means for AI to transform healthcare at scale. Venky brings a refreshingly honest and structured perspective to a conversation that is often dominated by hype, breaking down why AI is fundamentally different from every other technology wave healthcare has been through, laying out the five areas where Infosys is seeing real traction with payers, providers, and PBMs right now, and sharing the story behind two exciting developments: the acquisition of Optimum Health IT and the Pacesetters podcast and executive leadership community. If you are a healthcare leader trying to figure out where to start or how to think about AI as a whole-enterprise challenge rather than a point solution, this episode is essential listening. In this episode, they talk about: AI is not a point solution; it is a new operating system that will touch every function in every organization Healthcare is broken, fragmented, and frustrating, and AI is the first technology with the potential to fix all three at once Legacy modernization must come before AI adoption because you cannot layer intelligence on top of broken processes AI can now reverse engineer legacy systems that used to depend entirely on tribal knowledge The five pillars of AI transformation are strategy and engineering, legacy modernization, data, process reengineering, and physical AI Training AI on your own private data is the competitive wedge that separates leaders from followers Agents are the new team members, and organizations need to rethink how humans and agents orchestrate workflows together Infosys acquired Optimum Health IT, the number one-ranked Epic implementation partner according to KLAS, to deepen its provider capabilities Epic now covers an estimated 220 to 230 million distinct patients in the US and is growing internationally The Pacesetters podcast and annual executive gathering bring together CIOs, CTOs, academics, and analysts for candid, off-the-record dialogue about the future of healthcare A Little About Venky Ananth: Venky is a technology and transformation executive with deep experience leading a global business unit, scaling high-performance organizations, and delivering large-scale change through AI, cloud, and modern growth operating models. His career has focused on helping enterprises modernize core systems, improve operational efficiency, and unlock new growth through platform innovation and disciplined execution. He founded and scaled Infosys Helix, a cloud-native platform business that continues to shape payer and health platform modernization. In addition, he has led global teams across engineering, delivery, consulting, and product, giving him a broad view of strategy, technology, operations, and organizational scale. He operates at the intersection of technology, business model transformation, and leadership development, with a track record of strengthening enterprise performance and building organizations capable of sustained growth. Beyond his operating role, I host PaceSetters, a CXO leadership platform featuring conversations with leaders from healthcare, academia, private equity, and technology.