GeneInCell

Vinod Reddy Lekkala
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GeneInCell-The AI-powered Biotech Podcast focuses on crisp, science-based podcasts on stem cells, organoids, and gene editing—tracking breakthroughs from bench to bedside for better human health, including Biotech and business.

  1. Silencing Genetic Disease with shRNA | GeneInCell | 2026

    4일 전

    Silencing Genetic Disease with shRNA | GeneInCell | 2026

    shRNA is a gene-silencing tool that uses the cell’s own RNA interference machinery to reduce harmful protein production. In this episode, we explore how short hairpin RNAs are designed to target specific mutant genes, how they are delivered into cells, and why they hold promise for treating genetic disease through long-lasting gene knockdown.

    1시간 4분
  2. Base Editing- Rewriting DNA One Letter at a Time | GeneInCell | 2026

    5월 24일

    Base Editing- Rewriting DNA One Letter at a Time | GeneInCell | 2026

    Base editing is changing the future of gene editing by allowing scientists to rewrite DNA one letter at a time. In this episode, we explore how base editors work, why they offer a more precise alternative to traditional CRISPR cutting, and how they are being used to correct disease-causing mutations. We also look at their growing potential in research and medicine, along with the challenges that remain for safe and effective clinical use.

    55분
  3. siRNAs: Programmable Drugs for Silencing Genetic Disease | GeneInCell

    5월 16일

    siRNAs: Programmable Drugs for Silencing Genetic Disease | GeneInCell

    siRNAs are transforming medicine by acting as programmable drugs that selectively silence disease-causing genes. In this episode, we explore how small interfering RNAs work through the RNA interference pathway, why they are so powerful for precision therapeutics, and how they are being developed to treat genetic, metabolic, liver, and rare diseases. We also discuss delivery challenges, clinical progress, and what makes siRNA one of the most promising platforms in modern drug development.

    1시간 5분
  4. Prime editing: Search and replace for human DNA | GeneInCell | 2026

    5월 9일

    Prime editing: Search and replace for human DNA | GeneInCell | 2026

    Prime editing is a next-generation gene editing tool designed to precisely rewrite DNA—like a search-and-replace function for the human genome. In this episode, we break down how prime editing works, the chemistry behind it, and why it offers a powerful alternative to traditional CRISPR by making targeted changes without creating double-strand breaks. We also explore its applications in disease correction, its growing path toward the clinic, and the key challenges that still stand in the way.

    58분
  5. New Approach Methodologies (NAMs) for Replacing Animal Models in Drug Discovery | GeneInCell | 2026

    4월 5일

    New Approach Methodologies (NAMs) for Replacing Animal Models in Drug Discovery | GeneInCell | 2026

    NAMs are changing how new drugs are developed. We discuss organoids, tissue chips, and AI-based tools, along with the growing FDA and NIH push toward more human-relevant methods that can improve prediction, reduce reliance on animal models, and help bring safer treatments forward faster.

    45분
  6. Growing replacement kidneys from stem cells | GeneInCell | 2026

    3월 15일

    Growing replacement kidneys from stem cells | GeneInCell | 2026

    Can we grow new kidneys from stem cells? In this episode, we explore how scientists are using pluripotent stem cells to create kidney organoids that mimic early kidney development. We discuss how these mini-organs help study kidney disease, test new drugs, and move us closer to future regenerative therapies for kidney failure.

    52분
  7. Is Space Travel Safe For You? | GeneInCell | 2026

    3월 1일

    Is Space Travel Safe For You? | GeneInCell | 2026

    What really happens to your cells under stress, in space, and during space travel? In this episode, we zoom in on the physiological, cellular, and molecular levels to uncover how zero gravity affects them.

    49분
  8. Growing Beating Human Hearts in a Dish | Heart Organoids | GeneInCell

    2월 22일

    Growing Beating Human Hearts in a Dish | Heart Organoids | GeneInCell

    What does it take to grow a beating human heart in the lab? This episode explores cardiac organoids—self-organizing heart tissues derived from human stem cells that contract, respond to drugs, and model human heart disease. We unpack how iPSCs are guided into cardiac lineages, how electrical and mechanical cues drive maturation, and why these beating mini-hearts are transforming drug safety testing, disease modeling, and the future of regenerative cardiology.

    16분
모두 보기(34개)

소개

GeneInCell-The AI-powered Biotech Podcast focuses on crisp, science-based podcasts on stem cells, organoids, and gene editing—tracking breakthroughs from bench to bedside for better human health, including Biotech and business.

정보

  • 제작진
    Vinod Reddy Lekkala
  • 방송 연도
    2025년 - 2026년
  • 에피소드
    34
  • 등급
    전체 연령 사용가
  • 저작권
    © Vinod Reddy Lekkala
  • 웹사이트 보기
    GeneInCell