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NASA Employees Protest Cuts In Formal Dissent Letter

The Trump administration has proposed cutting NASA’s budget by almost 25% and shutting down 19 currently operating science missions. On July 21, several hundred current and former employees of the space agency released an official letter of dissent, titled “The Voyager Declaration,” arguing against “rapid and wasteful changes which have undermined our mission.” Retired NASA astronaut Cady Coleman joins Host Flora Lichtman to explain why she felt compelled to add her signature to the letter of dissent. Guest: Dr. Cady Coleman is a retired NASA astronaut and the author of Sharing Space: An Astronaut’s Guide to Mission, Wonder, and Making Change. She’s based in Shelburne Falls, Massachusetts. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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How Alphafold Has Changed Biology Research, 5 Years On

Proteins are crucial for life. They're made of amino acids that “fold” into millions of different shapes. And depending on their structure, they do radically different things in our cells. For a long time, predicting those shapes for research was considered a grand biological challenge. But in 2020, Google’s AI lab DeepMind released Alphafold, a tool that was able to accurately predict many of the structures necessary for understanding biological mechanisms in a matter of minutes. In 2024, the Alphafold team was awarded a Nobel Prize in chemistry for the advance. Five years later after its release, Host Ira Flatow checks in on the state of that tech and how it’s being used in health research with John Jumper, one of the lead scientists responsible for developing Alphafold. Guest: John Jumper, scientist at Google Deepmind and co-recipient of the 2024 Nobel Prize in chemistry. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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How Common Household Products Pollute Our Indoor Air

You have probably given some thought to outdoor air pollution, whether it’s wildfire smoke or smog from traffic. You may even check AQI measurements on your phone. But what about the air inside your home? Host Flora Lichtman talks to civil and environmental engineer Nusrat Jung, who studies indoor air pollution, about how we create toxic air without even knowing it, and what we can do to avoid it. Guest: Dr. Nusrat Jung is a civil and environmental engineer at Purdue University. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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AI Was Supposed To Discover New Drugs. Where Are They?

AI is everywhere these days, and though there’s debate about how useful it is, one area where experts think it could be game-changing is scientific research. It promised to be particularly useful for speeding up drug discovery, an expensive and time-consuming process that can take decades. But so far, it hasn’t panned out. The few AI-designed drugs that have made it to clinical trials haven’t been approved, venture capital investment in these efforts has cratered in the last few years, and many startups have shut their doors. So why has it been so hard to make AI-designed drugs? What are the fundamental issues, and what does the future of this research look like? Joining Host Ira Flatow with some answers is Peter Coveney, who studies how chemistry discoveries can be sped up with algorithms and computers. Guest: Dr. Peter Coveney is a professor and director of the Centre for Computational Science at University College London. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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How Math Helps Us Map The World

It’s easy to take maps for granted. After all, most of us have a pretty good map in our pockets at all times, ready to show us how to get anywhere on the globe. But to make a map useful, you have to decide what to keep in and what to leave out—and, most importantly, which mathematical equations to use. Beyond navigating from point A to point B, math and maps come together for a wide variety of things, like working out the most efficient route to deliver packages, calculating the depth of the ocean floor, and more. Host Ira Flatow is joined by Paulina Rowińska, mathematician and author of Mapmatics: A Mathematician's Guide to Navigating the World, to go on a journey through the math at the heart of all kinds of maps. Guest: Dr. Paulina Rowińska is a mathematician, writer, science journalist and author of Mapmatics: A Mathematician's Guide to Navigating the World. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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Attention, Trivia Nerds! It’s A Food Science Fact Feast

After years of getting your emails and phone calls, we know that SciFri listeners are in the 99th percentile when it comes to nerdy knowledge. We’re putting your fact retention skills to the test with the first ever Super Food Science Excellence Trivia Blowout (SFSETBO). Host Flora Lichtman teams up with trivia kingpin Mangesh Hattikudur, co-host of the podcast “Part-Time Genius,” to quiz one lucky listener on her food science knowledge. Guest: Mangesh Hattikudur is the co-host of “Part-Time Genius” and co-founder of Kaleidoscope. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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Why Is The Scopes Trial Still Relevant 100 Years Later?

In July 1925, the Scopes “Monkey” Trial captivated the nation. On its face, the case was relatively straightforward: A Tennessee biology teacher named John Scopes was accused of teaching human evolution to his students. At the time, that was against state law. Both sides enlisted the help of big name lawyers to represent them, and the case turned into a national spectacle. But, why has the legacy of the case persisted? And what can it help us understand about our current moment? Host Ira Flatow talks with Brenda Wineapple, author of Keeping the Faith: God, Democracy, and the Trial that Riveted a Nation. Read an excerpt of the book at sciencefriday.com. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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How Do Bacteria Talk To Each Other?

Bacteria have been around for billions of years. Could they have come up with complex behaviors that we just don’t understand yet? Could they have their own language? Their own culture? Their own complex societies playing out right under, and in, our noses? Microbiologist Bonnie Bassler has been studying these questions for more than 30 years. She talks with Host Flora Lichtman about the wild world of bacterial communication, and how understanding microbes could help us understand ourselves. Guest: Dr. Bonnie Bassler is a microbiologist at Princeton University. The transcript for this episode is available at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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Why Morbid Curiosity Is So Common—And So Fun

At first blush, the plots of many horror movies don’t seem particularly appealing. Take “The Shining”: A murderous psychopath tries to kill his family in a haunted, secluded hotel. But horror movies have had devoted fans for as long as they’ve been around, and lately, scary movies and television shows like “Sinners” or “The Walking Dead” have made a big splash. Why? What draws us to horror? And why are some people more thrill-seeking or morbidly curious than others? Host Flora Lichtman talks with two psychologists on opposite poles of horror fandom to flesh out some of the answers: horrorphile and behavioral scientist Coltan Scriver, and psychology professor Ken Carter, who’s horrified by horror. Guests: Dr. Ken Carter is a psychology professor at Emory University and the author of Buzz!: Inside the Minds of Thrill-Seekers, Daredevils, and Adrenaline Junkies. Dr. Coltan Scrivner is a behavioral scientist at Arizona State University and the author of Morbidly Curious: A Scientist Explains Why We Can’t Look Away. Transcripts for each episode are available within 1-3 days at sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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You Share Your Gut Microbiome With Your Friends

The microbiome, the network of tens of trillions of microbes that live in and on our bodies, helps us digest food and protects us from diseases. And depending on what species of bacteria you have, your microbiome could impact your stress response, decision-making, and how likely you are to develop arthritis and depression. Scientists have known that your microbiome is partially shaped by your environment, and the people you spend your time with. But they haven’t had a lot of clarity on how exactly social networks outside of home and family impact our microbiome makeup. To learn more, a team from Yale University mapped the connections among 2,000 people in isolated villages in Honduras and compared their microbiomes to see how exactly their social closeness impacted their gut bacteria. And it turns out, we’re more connected to people in our lives than you may think. Their research was published in the journal Nature. Ira Flatow is joined by sociologist and physician Dr. Nicholas Christakis, who directs the Human Nature Lab at Yale University. He studies the biology of human social interactions and was an author on the recent paper. They discuss how the researchers worked with villages in Honduras to gather samples and how they can tell who your friends are, just by looking at your poop. Transcripts for each segment will be available after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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WNYC is New York's public radio podcast home, producing award-winning shows like Radiolab, On the Media, The New Yorker Radio Hour, Science Friday, and more. Our podcasts bring groundbreaking journalism, unforgettable storytelling, and essential conversations to millions of listeners across the city and around the world.

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