Infectious Disease Puscast

Vincent Racaniello

A review of the infectious diseases literature from the previous two weeks.

  1. 3 DAYS AGO

    Infectious Disease Puscast

    On episode #102 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 2/26 – 3/11/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Measles Outbreak — New Mexico, 2025 (CDC: MMWR) Epidemiology of HMPV and Other Respiratory Viral Infections Among Outpatients, 2016–2022 (OFID) Notes from the Field: Congenital Rubella Syndrome — Florida, 2025 (CDC: MMWR) Long-term efficacy and safety of the single-dose tetravalent Butantan dengue vaccine (Nature Medicine) Bacterial Clinical Outcomes in Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Infection: A Cohort Study (JID) Duration of therapy for Pseudomonas aeruginosa bacteremia – a post hoc subgroup analysis from the BALANCE randomized controlled trial (CID) Diagnostic Yield of Tongue Swab- Compared to Sputum-Based Molecular Testing for Tuberculosis in Four High-Burden Countries (CID) WHO recommends near point-of-care tests, tongue swabs, and sputum poolingfor TB diagnosis (WHO) Respiratory virus co-infection is a risk factor for adverse outcomes during Staphylococcus aureus bacteraemia (OFID) Balance Versus Bias: Correcting Misinformation About the 2025 ATS Community-Acquired Pneumonia Guidelines (CID) Fungal The Last of US Season 2 (YouTube) Immunomodulation in the Treatment of Disseminated Coccidioidomycosis (CID) Parasitic Comparison of six weeks doxycycline versus six weeks rifampicin or three weeks of the combination of doxycycline plus rifampicin in the treatment of onchocerciasis: a randomized, placebo-controlled, double-blind, phase 2 trial (OFID) Cutaneous Larva Migrans Within the United States Military Health System – Clinical Presentation and Association with Autochthonous Spread or International Travel (OFID) Miscellaneous Distinct prophage infections in colorectal cancer-associated Bacteroides fragilis (Communications Medicine) Rounding Styles on Inpatient Infectious Disease Consult Services: Impact on Education and Patient-Care Delivery (OFID) Possible quality indicators for clinical infectious diseases consultations – results from a hybrid Delphi-nominal group approach and scenario study (CMI: Clinical Microbiology and Infections) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    38 min
  2. 18 FEB

    Infectious Disease Puscast

    On episode #100 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/29/26 – 2/11/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis (PNAS) Dengue Suppression by Male Wolbachia-Infected Mosquitoes (NEJM) Assessing the impact of SARS-CoV-2 infection and vaccination on fertility and assisted reproductive techniques outcomes: an umbrella review (Vaccine) Prevalence of CSF HIV VIRAL Escape and Associations With Neurocognitive Outcomes Among HIV-Associated Meningitis Survivors: A Cohort Study (OFID) Adenoviral Inciting Antigen and Somatic Hypermutation in VITT (NEJM) Bacterial Extraintestinal Invasive Escherichia coli Infections in the US (JAMA Network OPEN) Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience (CID) US Emergency Department Visits forAntibiotic Adverse Drug Events in Children, 2019-2023 (Journal of the Pediatric Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Albumin orchestrates a natural host defence mechanism against mucormycosis (Nature) Pseudo-Outbreak of Purpureocillium lilacinum Skin Infections at a Dermatology Clinic — Washington, 2024 (CDC: MMWR) Candida auris Testing by the Antimicrobial Resistance Laboratory Network, United States, 2022–2023 (Emerging Infectious Diseases) Parasitic Trichinellosis: A zoonosis that still requires vigilance (PLoS Neglected Tropical Diseases) Trichinellosis after Raw Bear Eyeball Consumption (AJTMH: American Journal of Tropical Medicine and Hygiene) Moving Scabies Under Video-Dermoscopy (AJTMH: American Journal of Tropical Medicine and Hygiene) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    38 min
  3. 3 FEB

    Infectious Disease Puscast

    On episode #99 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/15/26 - 1/28/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Symptomatic and asymptomatic norovirus infections in early life; The PREVAIL Cohort, 2017-2020 (CID) Bacterial Xenodiagnosis to search for Borrelia burgdorferi after antibiotic treatment of Lyme disease: a prospective cohort study (CID) Diagnostic Yield of Repeat Blood Cultures and Risk Factors for Bloodstream Infection in Persistent Febrile Neutropenia (CID) Methodology Misrepresented: Correcting the Record on the ATS Community-acquired Pneumonia Guideline Process (CID) Pediatric Infectious Diseases Physicians' Preferences for Management of Clostridioides difficile Infection: An Emerging Infections Network Surve (Journal of the Pediatric Infectious Diseases Society) Antibiotic Therapy for Uncomplicated AcuteAppendicitis (JAMA) Fungal The Last of US Season 2 (YouTube) Persistence of Symptoms among Commercially Insured Patients with Coccidioidomycosis, United States, 2017–2023 (CDC: Emerging Infectious Diseases) Ophthalmologic evaluation and clinical outcome in candidemia: a seven-year retrospective multicenter cohort study (OFID) Parasitic Postinfectious Syndromes and Long-Term Sequelae after Giardia Infections (CDC: Emergining Infectious Diseases) Priced Out of Treatment: The Exorbitant Cost of Antiparasitic Drugs in the United States (OFID) Miscellaneous All About the AAP Recommended Immunization Schedule (healthychildren.org) Recommended Childhood and Adolescent Immunization Schedule: United States, 2026: Policy Statement (American Academy of Pediatrics: Pediatrics) Feeling the Vibes: An Investigation into Resident Antibiotic Prescribing Practices (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    40 min
  4. 23/12/2025

    Infectious Disease Puscast #96

    On episode #96 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/4/25 – 12/17/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Rabies Cluster Among Steer on a Dairy Farm — Minnesota, 2024 (CDC:MMWR) Incidence of community-acquired pneumonia and herpes zoster in people with HIV based on CD4-count and age in the current antiretroviral therapy era: a longitudinal cohort study (CID) Associations between antibiotic use and outcomes in patients hospitalized with community-acquired pneumonia and positive respiratory viral assays (CID) Bacterial Lactobacillus Bacteremia: A Challenging Condition for Pediatrician (Pediatric Infectious Disease Journal) Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis (NEJM) Zoliflodacin versus ceftriaxone plus azithromycin for treatment of uncomplicated urogenital gonorrhoea: an international, randomised, controlled, open-label, phase 3, non-inferiority clinical trial (LANCET) Fungal The Last of US Season 2 (YouTube) Compassionate Use of Olorofim for Invasive Mold Infections: A Nationwide Observational Study in France  (OFID) Parasitic Eliminating Guinea worm (LANCET: Infectious Disases) Balamuthia mandrillaris Encephalitis in a 12-Year-old Girl: Report of the First Case Diagnosed in Greece (Pediatric Infectious Disease Journal) A Prospective Cohort Longitudinal Study of Human Acute Babesiosis: Quality of Life and Severity of Symptoms Through 1-Year Follow-up (OFID) Body lice and scabies co-infestation among unsheltered migrants, refugees, and asylum seekers and the right to water and sanitation (PLoS Neglected Tropical Diseases) Miscellaneous H.U.S.T.L.E: A Consult Fitness Guide for Infectious Diseases Providers (CID) Seven alternatives to evidence based medical education: an exploration of how we actually teach (BMJ) What does a doctor look like?Asking AI (BMJ) The Receding Specialty of Infectious Diseases and Implications for U.S. Healthcare (OFID) Integrating a host biomarker with a large language model for diagnosis of lower respiratory tract infection (Nature Communications) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    39 min
  5. 09/12/2025

    Infectious Disease Puscast

    On episode #95 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/20/25 – 12/3/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Early low-dose dexamethasone is associated with shorter acute symptom duration in Chikungunya virus infection: a retrospective cohort study (BMC Infectious Diseases) Noninferiority of One HPV Vaccine Dose to Two Doses (NEJM) Evidence to Action — Single-Dose HPV Vaccination and Cervical HPV Infection (NEJM) Daily Mosnodenvir as Dengue Prophylaxis in a Controlled Human InfectionModel (NEJM) Universal Hepatitis B Vaccination at Birth—Risks of Revising the recommendation (JAMA) Correlates of HIV-1 control after combination immunotherapy (Nature) Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025 (CDC: MMWR) Cytomegalovirus-specific cell-mediated immunity for prediction of post-prophylaxis CMV disease in a phase 3 trial of letermovir vs valganciclovir prophylaxis in donor CMV-seropositive recipient CMV-seronegative kidney transplant recipients (CID) An Analysis of Cytomegalovirus-Specific Cell-Mediated Immunity in a Phase 3, Randomized, Placebo-Controlled Trial of Letermovir Prophylaxis in Cytomegalovirus-Seropositive Recipients of an Allogeneic Hematopoietic Cell Transplant (CID) Bacterial Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update (CID) Lyme DiseaseIncidence in Massachusetts, 2012-2024 (JAMA: Open Network) Fungal The Last of US Season 2 (YouTube) Aspergillosis-Attributable Mortality in the United States: Analysis of Death CertificateData (CID) Oral itraconazole versus oral voriconazole for treatment-naive patients with chronic pulmonary aspergillosis in India (VICTOR-CPA trial): a single-centre, open-label, randomised, controlled, superiority trial (LANCET: Infectious Diseases) Parasitic Loa loa encephalopathy following treatment with benzimidazole derivatives: A systematic review (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    43 min
  6. 25/11/2025

    Infectious Disease Puscast

    On episode #94 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/11/25 – 11/19/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus (Science Translational Medicine) Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice (CID) Antimicrobial drug-resistant Neisseria gonorrhoeae (GC) infections in men using doxycycline postexposure prophylaxis. A substudy of the ANRS 174 DOXYVAC trial (CID) HIV Pre-exposure Prophylaxis Does Not Increase Gonorrhea and Chlamydia Incidence in Young Black and Hispanic Men who Have Sex With Men: An Observational Cohort Study (OFID) Bacterial Global and regional knowledge of antibiotic use and resistance among the general public: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) Infant Botulism Outbreak Linked to Infant Formula, November 2025 (CDC: Botulism) Outbreak Investigation of Infant Botulism: Infant Formula (November 2025) (FDA) Vitamin D deficiency at hospital admission with community-acquired pneumonia is associated with increased risk of mortality: A Prospective Cohort Study (OFID) Bat-Associated Hemotropic Mycoplasmas in Immunosuppressed Children, Spain, 2024 (Emerging Infectious Diseases) A Multicomponent Intervention to Improve Maternal Infection Outcomes (NEJM) Fungal The Last of US Season 2 (YouTube) Increasing Fluconazole Resistance in Candida parapsilosis: A 10-Year Analysis of Blood Culture Isolates at a US Reference Laboratory (2015–2024) (JID) British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update (LANCET: Infectious Diseases) In Vivo Evolution of Candida auris Multidrug Resistance in a Patient Receiving Antifungal Treatment (JID) Parasitic Implications of a fatal anaphylactic reaction occurring 4 hours after eating beef in a young man with IgE antibodies to galactose-α-1,3-galactose (JACI: Journal of Allergy and Clinical Immunology In practice) WHO recommends R21/Matrix-M vaccine for malaria prevention in updated advice on immunization (WHO) Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi (LANCET: Global Health) A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication? (PLoS Neglected Tropical Diseases) Miscellaneous IL12RB1 deficiency appearing in North America: expanding the clinical phenotypes (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    46 min
  7. 12/11/2025

    Infectious Disease Puscast

    On episode #93 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 10/23/25 – 11/10/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral High Prevalence of Varicella Zoster Virus Infection among Persons with Suspect Mpox Cases during an Mpox Outbreak in Kenya, 2024 (ASTMH: AJTMH) Earlier initiation of treatment following HIV acquisition reduces non-AIDS-defining malignancy risk (CID) TWiV 1267: A cancer vaccine and an mpox treatment (MicrobeTV) Cancers Caused by HPV (CDC: Human Papillomavirus (HPV)) Circulating tumor human papillomavirus DNA whole genome sequencing enables human papillomavirus-associated oropharynx cancer early detection (Journal of the National Cancer Institute) Impact of Vaccinating Adult Women Who Are HPV-Positive or with Confirmed Cervical SIL with the 9-Valent Vaccine—A Systematic Review (Viruses) ACIP Shared Clinical Decision-Making Recommendations (CDC: Advisory Committee on Immunization Practices (ACIP)) HPV Vaccination Recommendations (CDC: Vaccines & Immunizations) Bacterial Consequences of Delaying Surgical Intervention in Patients with Native Joint Septic Arthritis (OFID) Fungal The Last of US Season 2 (YouTube) Adjunctive corticosteroids in non-AIDS patients with severe Pneumocystis jirovecii pneumonia (PIC): a multicentre, double-blind, randomised controlled trial (LANCET: Respiratory Medicine) Nasal Iodophor to Reduce Candidozyma auris Nasal Carriage in Nursing Home Residents (OFID) Epidemiology of Invasive Fungal Disease in Pediatric Heart Transplant Recipients (Journal of Pediatric Infectious Diseases Society) Mapping the Geographic Distribution of Dimorphic Mycoses Using a US Commercial Insurance Database (OFID) Genomic Dynamics of the Emergent Candida auris: Exploring Climate-dependentTrends (OFID) Parasitic Evaluation of a One Health public health program based on minimum inputs to control Taenia solium in Madagascar (PLoS Neglected Tropical Diseases) Transplacental Transfer of Lumefantrine, Mefloquine, and Piperaquine: A Comparison of Concentrations in Mothers, Neonates, and Cord Blood (CID) Miscellaneous Amplifying Our Voices: Fostering Advocacy in Infectious Diseases Fellowship(OFID) Plant-Based Diets and Climate Change, A Perspective for Infectious Disease Provider (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    42 min
  8. 28/10/2025

    Infectious Disease Puscast

    On episode #92 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 10/9/25 – 10/22/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Long-term clinical, immunologic, and viral reservoir outcomes in children treated with VRC01LS and 10-1074 monoclonal antibodies in the Tatelo Study (CID) Resistance Analyses of Lenacapavir, Emtricitabine/Tenofovir Alafenamide and Emtricitabine/Tenofovir Disoproxil Fumarate in the PURPOSE 1 and 2 Studies (JID) Susceptibility of measles virus to WHO hand rubs, oral and surface disinfectants (OFID) Measles without rash during acute febrile illness surveillance in Tanzania, 2023-2024 (CID) The 2025 Centers for Disease Control and Prevention Non-Occupational HIV Post-Exposure Prophylaxis Guidelines (CID) Bacterial Paratyphoid fever and relapsing fever in 1812 Napoleon's devastated army (Current Biology) Mass Administration of Azithromycin to Infants in Mali to Reduce Mortality (NEJM) Efficacy and safety of tedizolid in the treatment of acute bacterial skin and skin-structure infections (CMI: Clinical Microbiology and Infection) Zoonotic Escherichia coli and urinary tract infections in Southern California (mBio) Cefdinir Versus Cephalexin for the Treatment of Uncomplicated Urinary Tract Infections (OFID) Fungal The Last of US Season 2 (YouTube) Antagonistic in vitro interaction between olorofim and voriconazole against Aspergillus fumigatus (Journal of Antimicrobial Chemotherapy) Parasitic Miscellaneous CARB Your Enthusiasm: An Ethics-Informed Analysis for Clinicians of the US National Action Plan for Combating Antibiotic-Resistant BacteriaCID) Infection Control in Carceral Facilities (CID) Infection Prevention and Control in Carceral Settings (CID) The Challenge of Malignancies in HIV-1, Beyond Immune Activation and Back to Decreased Immune Surveillance (Journal of AIDS & Clinical Research) SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade (Nature) TWiV 1265: mRNA vaccines make cancer treatment great again (microbeTV) Infected With the Academic Bug (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    37 min

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A review of the infectious diseases literature from the previous two weeks.

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