Moonshots with Peter Diamandis

PHD Ventures

Tracking the future of technology and how it impacts humanity. Named by Fortune as one of the “World’s 50 Greatest Leaders,” Peter H. Diamandis, MD, is a founder, investor, advisor, and best-selling author. Join Peter on his mission to uplift humanity through technology. Follow Peter on X - https://x.com/PeterDiamandis

  1. 16 hr ago

    Pope Leo vs. AI, GPT 5.5 Beats Claude, and Sam Altman Walks Back Job Apocalypse | EP #259

    This episode is a sprawling Moonshots roundup with three big pillars: AI governance and religion, AI’s impact on jobs and entrepreneurship, and a moon/space-compute future centered on SpaceX, Starlink, and Tesla. Education survey: Moonshots.com/survey Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 Salim Ismail is the founder of Open ExO, a GP at Exponential Venture Capital/The Organizational Singularity Fund and a sought after global speaker and thought leader. Apply for Salim’s Pilot Program: https://openexo.com/organizational-singularity-pilot?video=I9c8STV7Hnw Dave Blundin is the founder & GP of Link Ventures Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter  _ Connect with Peter: X Instagram Substack Website Xprize Connect with Dave: Web X LinkedIn Instagram TikTok Connect with Salim: LinkedIn X Apply for Salim’s Pilot Program  Subscribe to Salim’s YouTube channel Exponential Venture Capital Resources: https://openexo.com/resource-hub  Connect with Alex Website LinkedIn X Email Substack  Spotify Threads Listen to MOONSHOTS: Apple YouTube – *Recorded on May 28th, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

    1hr 49min

  2. 4 days ago

    The Organizational Singularity: AI-Proof Your Company | EP #258

    This episode is a deep dive on the “organizational singularity”: how AI agents, AI-native workflows, and recursive self-improvement will restructure companies much faster than traditional hierarchy can adapt. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 Salim Ismail is the founder of Open ExO, a GP at Exponential Venture Capital/The Organizational Singularity Fund and a sought after global speaker and thought leader. Apply for Salims Pilot Program – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter  _ Connect with Peter: X Instagram Substack Website Xprize Connect with Salim: LinkedIn X Apply for Salim's Pilot Program Subscribe to Salim’s YouTube channel Exponential Venture Capital Listen to MOONSHOTS: Apple YouTube – *Recorded on May 16th, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

    1hr 3min

  3. 23 May

    SpaceX’ $75B+ Historic IPO, GPT 5.5 Outperforms Polymarket, and AI Solves 80 yr old math problem | EP #257

    In this episode, the Moonshot mates discuss SpaceX's record-breaking IPO filing and its growing ties to Anthropic, OpenAI's AI model disproving a decades-old Erdős conjecture in mathematics, and GPT-5.5 beating prediction markets at forecasting. Get access to metatrends 10+ years before anyone else - ⁠https://qr.diamandis.com/metatrends⁠   Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 Salim Ismail is the founder of OpenExO Dave Blundin is the founder & GP of Link Ventures Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified Apply for Salim’s Pilot Program: https://openexo.com/organizational-singularity-pilot?podcast=23.5.26 Subscribe to Salim’s channel: https://www.youtube.com/@salimismail – My companies: Apply to Dave's and my new fund: ⁠https://qr.diamandis.com/linkventures...⁠ Go to Blitzy to book a free demo and start building today: ⁠https://qr.diamandis.com/blitzy⁠ Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: ⁠https://www.fountainlife.com/peter⁠ _ Connect with Peter: ⁠X⁠ ⁠Instagram⁠ ⁠Substack⁠ ⁠Website⁠ ⁠Xprize⁠ Connect with Dave: ⁠Web⁠ ⁠X⁠ ⁠LinkedIn⁠ ⁠Instagram⁠ ⁠TikTok⁠ Connect with Salim: ⁠X⁠ ⁠Join Salim's Workshop to build your ExO⁠  Connect with Alex ⁠Website⁠ ⁠LinkedIn⁠ ⁠X⁠ Email ⁠Substack⁠  ⁠Spotify⁠ ⁠Threads⁠ Listen to MOONSHOTS: ⁠Apple⁠ ⁠YouTube⁠ – *Recorded on May 21st, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

    1hr 53min

  4. 9 May

    Google's Record Quarter, the White House Intervenes, and GPT 5.5 Silently Matches Mythos | EP 254

    In this episode, the mates welcome Blitzy CEO Brian Elliott to discuss Google’s blowout AI-driven earnings, White House model vetting, Pentagon deals with frontier labs, compute scarcity, the rise of private-equity-led enterprise AI, ocean and space data centers, OpenAI’s changing cloud strategy and delayed IPO talk, AGI definitions, AI risk/insurance, and the growing role of AI in GDP and infrastructure. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 Brian Elliott, Co-Founder and CEO of Blitzy. Learn about Blitzy AI Salim Ismail is the founder of OpenExO Dave Blundin is the founder & GP of Link Ventures Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter  _ Connect with Peter: X Instagram Substack Website Xprize Connect with Brian LinkedIn Blitzy.com Connect with Dave: Web X LinkedIn Instagram TikTok Connect with Salim: X Join Salim's Workshop to build your ExO  Connect with Alex Website LinkedIn X Email Substack  Spotify Threads Listen to MOONSHOTS: Apple YouTube – *Recorded on May 6th, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

    2h 9m

  5. 4 May

    Google Invests $40B Into Anthropic, GPT 5.5 Drops, and Google Cloud Dominates | EP #252

    In this episode, the mates explore the rapid advancements in AI, the global AI race, new models like Kimi K 2.6 and GPT 5.5, and the implications for privacy, security, and the future of technology. The mates discuss the future of work, AI regulation, and transformative biomedical breakthroughs. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 Salim Ismail is the founder of OpenExO Dave Blundin is the founder & GP of Link Ventures Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter  _ Connect with Peter: X Instagram Substack Website Xprize Connect with Dave: Web X LinkedIn Instagram TikTok Connect with Salim: X Join Salim's Workshop to build your ExO  Connect with Alex Website LinkedIn X Email Substack  Spotify Threads Listen to MOONSHOTS: Apple YouTube – *Recorded on April 28th, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

    2h 20m

  6. 28 Apr

    David Sinclair: The GLP-1 Side Effect No One Talks About, What AI Found in His Lab, and Reversing Blindness | Q&A EP #251

    This episode was filmed at the 2026 Abundance360 Summit. Learn more at https://www.abundance360.com/ This Q&A is about longevity, and especially how David Sinclair sees AI speeding up drug discovery, biological-age reversal, and the future of healthspan. It also covers GLP-1s, telomeres, genetics, muscle preservation, hormone replacement, indoor environment, and the role of mindset in aging well. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 David A. Sinclair, A.O., Ph.D., is a tenured Professor of Genetics at Harvard Medical School and a serial biotech entrepreneur. Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter  _ Connect with Peter: X Instagram Substack Website Xprize Connect with David  X Instagram Website Listen to MOONSHOTS: Apple YouTube – *Recorded on March 9th, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

    27 min

  7. 27 Apr

    David Sinclair on the Longevity Pill, Age Reversal Timelines, and Updated Protocols | EP #250

    This episode was filmed at the 2026 Abundance360 Summit. Learn more at https://www.abundance360.com/ In this insightful interview, Dr. David Sinclair discusses groundbreaking advancements in longevity research, including epigenetic reprogramming trials, the potential for extending human lifespan, and accessible therapies. He shares his personal protocols and the future of anti-aging science, emphasizing the importance of innovation and community support. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   David A. Sinclair, A.O., Ph.D., is a tenured Professor of Genetics at Harvard Medical School and a serial biotech entrepreneur.  Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter  _ Connect with Peter: X Instagram Connect with David X Instagram  Website Listen to MOONSHOTS: Apple YouTube – *Recorded on March 9th, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

    33 min

  8. 23 Apr

    Iran's AI Supply Chain Threat, Claude vs. SaaS, and Elon's $60B Cursor Bet | EP #249

    In this episode, the mates center on the Iran oil shock as a broader system shock, Anthropic’s Claude Design and the “unhobbled” frontier-lab threat to vertical software, the AI job transition, UAP disclosure, the power and geopolitics of data centers, China’s solar and robotics push, and the future of entrepreneurship and agency. Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Peter H. Diamandis, MD, is the Founder of XPRIZE, Singularity University, ZeroG, and A360 Salim Ismail is the founder of OpenExO Dave Blundin is the founder & GP of Link Ventures Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Your body is incredibly good at hiding disease. Schedule a call with Fountain Life to add healthy decades to your life, and to learn more about their Memberships: https://www.fountainlife.com/peter  _ Connect with Peter: X Instagram Connect with Dave: Web X LinkedIn Instagram TikTok Connect with Salim: X Join Salim's Workshop to build your ExO  Connect with Alex Website LinkedIn X Email Substack  Spotify Threads Listen to MOONSHOTS: Apple YouTube – *Recorded on April 21st, 2026 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

    2h 35m
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Tracking the future of technology and how it impacts humanity. Named by Fortune as one of the “World’s 50 Greatest Leaders,” Peter H. Diamandis, MD, is a founder, investor, advisor, and best-selling author. Join Peter on his mission to uplift humanity through technology. Follow Peter on X - https://x.com/PeterDiamandis

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