Talk Python To Me

Michael Kennedy

Talk Python to Me is a weekly podcast for Python developers, data scientists, and AI builders, hosted by developer and entrepreneur Michael Kennedy. We dive deep into the packages, tools, and people shaping Python, from web development and data science to AI and LLMs. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from its leaders. And if you've been Pythoning for years, you'll hear about your favorite packages and the hot new ones coming out of open source.

  1. 22 Sept

    EVE Online Departs for Python 3

    Every ship in EVE Online eventually undocks and leaves the station. This time, it's the whole game. EVE has run on Python 2 since it launched in 2003, all 2.4 million lines of it, on a custom Stackless interpreter that stopped at 3.8 and was archived last year. Destination: Python 3.12. The route runs through 6,500 lines of division that decide who wins a fight, and 100 gigabytes of pickled Python objects that have to survive the jump intact. Kristinn Sigurbergsson was on this show ten years ago. He's back, with Jamie Bannister, who is flying the EVE Online migration right now, and Thomas Dähling, who took EVE Frontier through first. In EVE, a destroyed ship is gone for good. There are no do-overs, and the universe has to stay online the whole way. Episode sponsors Sentry Error Monitoring, Code talkpython26 Talk Python Courses Links from the show Guests Jamie Bannister: linkedin.com Thomas Dähling: linkedin.com Kristinn Sigurbergsson: linkedin.com EVE Online: www.eveonline.com EVE Frontier: evefrontier.com 2.4 million lines of Python: www.eveonline.com Example of graphics, ships walk-through: www.youtube.com Stackless: www.stackless.com futurize: python-future.org blue: github.com Dev blog on the Frontier upgrade: evefrontier.com Upgrading CARBON to Python 3: www.youtube.com carbon-scheduler: github.com Scheduling in Carbon: Leaving Stackless Python Behind: www.youtube.com All of Carbon is on GitHub now: github.com did a whole course: training.talkpython.fm Trade Wars BBS (Wikipedia): en.wikipedia.org TW 3002 - TradeWars 2002, reimagined as a modern browser game: www.reddit.com Watch this episode on YouTube: youtube.com Episode #564 deep-dive: talkpython.fm/564 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy

  2. 16 Sept

    Getting Started with Rust as Python Devs

    Lint the entire CPython code base from scratch. It takes 0.3 seconds. Three blinks of an eye. That is ruff, and it is written in Rust. So are Pydantic, Polars, uv, and Granian. Rust shows up in Python three ways: tools that happen to be Rust, libraries Python imports, and servers that run Python inside Rust. This is Rust for Python developers, not Rust experts. Christopher Trudeau is back on Talk Python to discuss Rust and his latest course Up and Running with Rust. The core rule is that only one thing can own a value at a time. Pass it around freely in Python and the garbage collector cleans up. Do that in Rust and it will not compile. Episode sponsors Sentry Error Monitoring, Code talkpython26 Python in Production Talk Python Courses Links from the show Up and Running with Rust course: training.talkpython.fm Rust: rust-lang.org pydantic: pydantic.dev ruff: docs.astral.sh granian: github.com By example: doc.rust-lang.org rust-lang.org: rust-lang.org rustup.rs: rustup.rs crates.io: crates.io main.rs: main.rs PyO3: github.com https://github.com/ritwiktiwari/awesome-python-rs: github.com ty: docs.astral.sh pyrefly: pyrefly.org uv: github.com polars: pola.rs Watch this episode on YouTube: youtube.com Episode #563 deep-dive: talkpython.fm/563 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy

  3. 10 Sept

    DuckLake: The Lakehouse That's Just SQL and Parquet

    How many files does your query read before it reads any data? On some data lakes, you go through JSON and metadata files first, just to learn which Parquet files matter. DuckLake asks one SQL question instead. The metadata lives in a real database. The data stays in plain Parquet. That's the entire format. Pedro Holanda joined DuckDB in 2018, when it was still a research prototype at CWI. He's the lead DuckLake developer. Guillermo Sanchez Dionis works on DuckLake and the new Quack protocol. With Quack as the catalog, DuckLake handles 200 transactions a second under heavy contention. No other open table format comes close. Episode sponsors Six Feet Up Talk Python Courses Links from the show Guests Pedro Holanda: pedroholanda.org Guillermo Sanchez: linkedin.com PhD on progressive indexes: ir.cwi.nl SQLite: www.sqlite.org Litestream: litestream.io boring hardware: talkpython.fm DuckDB: duckdb.org episode 491: talkpython.fm Iceberg: iceberg.apache.org manifesto: ducklake.select DuckLake: ducklake.select spec: ducklake.select this diagram: blobs.talkpython.fm Data inlining: ducklake.select ducklake-dataframe: github.com Polars course: training.talkpython.fm CSV parser: duckdb.org Zero-copy Arrow: duckdb.org ART index: duckdb.org async I/O: duckdb.org v1.0: ducklake.select Git-like branching: ducklake.select Watch this episode on YouTube: youtube.com Episode #562 deep-dive: talkpython.fm/562 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy

  4. 4 Sept

    TonIO, a Multi-threaded Async Runtime for Python

    How many cores does your machine have, 10, 18? Your async Python code uses just one of them. That isn't a bug in asyncio. That's the design, and optimizing event loops to be faster by 20% doesn't change it. So Giovanni Barillari started over. Joe is the creator of Granian, the Rust-based server that powers Talk Python. His new project is TonIO, an async runtime written from scratch for free-threaded Python. Real threads, a handful of primitives instead of asyncio's pile of them, and it flat out refuses to start if the GIL is on. Episode sponsors Sentry Error Monitoring, Code talkpython26 Python in Production Talk Python Courses Links from the show Guest Giovanni Barillari: github.com Granian: github.com Hyper: github.com Free threaded Python: docs.python.org Sort of: labs.quansight.org did a whole course: training.talkpython.fm uvloop: github.com rloop: github.com TonIO: github.com your EuroPython 2026 talk: www.youtube.com Michael's Cutting Python Web App Memory Over 31% Article: mkennedy.codes Watch this episode on YouTube: youtube.com Episode #561 deep-dive: talkpython.fm/561 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy

  5. 26 Aug

    Building a Research OS: From Django to 30,000 Samples

    In 2020, a gastroenterologist in Glasgow did the math on his new research study and came up with 30,000 samples, arriving over two years from three cities and a dozen hospitals. He asked around about how researchers keep track of that. The answer was Microsoft Excel. Shaun Chuah had written some HTML by hand in Notepad back in high school and that was about the whole of his programming experience, so he opened the Django tutorial and started reading. Six years later that app is Foundry120, holding 10 terabytes of clinical and genomics data with an agentic AI running on top of it. Episode sponsors Sentry Error Monitoring, Code talkpython26 Talk Python Courses Talk Python Courses Links from the show Guest Shaun Chuah: github.com Up and Running with Rust Course: talkpython.fm Foundry120: www.foundry120.com Designing Data Intensive Applications: www.oreilly.com Microsoft Foundry: ai.azure.com ChatIBD: www.chatibd.com Blog: shaunchuah.github.io @drshaunchuah: x.com github.com/shaunchuah: github.com Watch this episode on YouTube: youtube.com Episode #560 deep-dive: talkpython.fm/560 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy

  6. 19 Aug

    12 Things You Should (and Shouldn't) Do in AWS

    Your site is down. It's 3am. Is it a bug, a bill, or a breach? You can't tell yet, and everyone is watching you find out. Matt Lea has spent fifteen years being the person companies call when an outage is costing them real money per hour, and his whole argument is that everything you'd want in that moment gets decided months earlier, on ordinary afternoons, when someone chose the convenient thing. We walk his top twelve dos and don'ts in AWS - infrastructure as code, IAM roles instead of access keys, private subnets, no wildcards, no public buckets - and I push on which of them actually matter if you're one person on a small VPS. Then we get to Cloud War Games, where Matt breaks things on purpose so your team's first real incident isn't their first incident. Let's get into it. Episode sponsors Sentry Error Monitoring, Code talkpython26 Talk Python Courses Talk Python Courses Links from the show Guest Matt Lea: linkedin.com Talk Python Certificates: training.talkpython.fm/certificates Schematical: schematical.com CloudWarGames.com: cloudwargames.com Zero to Hero on AWS Security: www.oreilly.com Repo: github.com Custom Wheel Offset: customwheeloffset.com 2012 TechCrunch Disrupt Hackathon: techcrunch.com tech comics: schematical.com shhgit: github.com Zero Trust in 200ms: Implementing Identity-Per-Transaction: us.pycon.org Coolify: coolify.io returned to full GA Nov 2025: aws.amazon.com Signed URLs/cookies: docs.aws.amazon.com Cloudflare: www.cloudflare.com Bunny Shield: bunny.net Cloud War Games One: www.youtube.com Cloud War Games Two: www.youtube.com LinkedIn: linkedin.com YouTube: youtube.com KnocKnoc: knocknoc.io Watch this episode on YouTube: youtube.com Episode #559 deep-dive: talkpython.fm/559 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy

  7. 10 Aug

    Hyper-Personal Software with Python

    Every company has one. The little internal tool that Jane built back in 2021, and then Jane left. Nobody understands it, nobody will touch it. There are two unwritten rules around it: don't change it, it's working. And if you break it, you bought it. That's dark-matter enterprise software. For every app you can actually see, there are ten of these sitting in the shadows, frozen. Michael Booth thinks that just changed. He read my article on hyper-personal software and ran with it, writing about hyper-team software: small teams inside big companies finally building the tools that were never going to get built. We cover where this works, where it quietly goes wrong, and the guardrails that keep it from turning into a mess. Let's get into it. Episode sponsors Sentry Error Monitoring, Code talkpython26 Python in Production Talk Python Courses Links from the show Guest Michael Booth: github.com Talk Python AI Integrations: talkpython.fm/blog From Hyper-Personal to Hyper-Team Software: Small Team-Built, AI-Assisted Tools Inside the Enterprise: www.databooth.com.au What hyper-personal software looks like (MK's article): mkennedy.codes Databooth Site: www.databooth.com.au Wall Street just lost $285 billion because of 13 markdown files: martinalderson.com SaaSpocalypse is real but everyone is panicking about the wrong thing: www.reddit.com Warp Terminal: www.warp.dev Watch this episode on YouTube: youtube.com Episode #558 deep-dive: talkpython.fm/558 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy

  8. 2 Aug

    Security of everything at PyCon 2026

    Security has always been the vegetables of software. Everyone agrees it matters, and somehow it never quite makes it onto the plate. At PyCon US this year, that changed. For the first time ever, security got its own dedicated, day-long track, one of just two at the whole conference, sitting right next to AI. And the room was packed to the back wall. On this episode, I'm joined by the three people at the center of it. Seth Larson, Security Developer in Residence at the Python Software Foundation and, very recently, a CPython core developer. Juanita Gomez, a PhD researcher at UC Santa Cruz in open source security, who co-chaired the track. And Mike Fiedler, PyPI's Safety and Security Engineer, one of the very few people paid full-time to keep the packages you install safe. We use the arc of the track's talks to take the temperature of Python security right now: supply chain attacks, dependency cooldowns, zero trust, SBOMs, and the push to bring Rust into CPython. And why not one of us thinks security is anywhere close to solved. Turns out that's the good news. It's why the room was full. Episode sponsors Sentry Error Monitoring, Code talkpython26 Talk Python Courses Links from the show Guests Juanita Gomez: linkedin.com Mike Fiedler: miketheman.dev Seth Michael Larson: sethmlarson.dev Trailblazing Python Security: us.pycon.org Everything Security at PyCon US 2026 (PSF blog): pyfound.blogspot.com Dependency Cooldowns: cooldowns.dev Anatomy of a Phishing Campaign (Mike Fiedler) Recording: www.youtube.com FedRAMP: www.gsa.gov Zero Trust in 200ms: Implementing Identity-Per-Transaction with Python & Serverless-Tristan McKinnon: www.youtube.com Rust for CPython project: blog.python.org pre-PEP: discuss.python.org Rust for CPython: Making Python Safer and More Robust for Everyone - Emma Smith: www.youtube.com SBOMit: github.com Asleep at the Wheel: Getting your SBOMs to pay attention... - Sanchit Sahay, Abhishek Reddypalle: www.youtube.com Volatility: volatilityfoundation.org Post Incident Runtime SBOM Generation from Python Memory - Hala Ali: www.youtube.com zizmor: docs.zizmor.sh GitHub Actions security in Python packages (Andrew Nesbitt write-up): nesbitt.io andrew/pycon: data & analysis for the GitHub Actions security talk: github.com GitHub Actions Security in Python Packages - Andrew Nesbitt: www.youtube.com gh-profiler: examine a GitHub user's profile to gauge their contributions: github.com PyCon US YouTube channel: www.youtube.com SBOMit: adding verification to SBOMs (OpenSSF): openssf.org Ecosystems: ecosyste.ms Watch this episode on YouTube: youtube.com Episode #557 deep-dive: talkpython.fm/557 Episode transcripts: talkpython.fm Theme Song: Developer Rap 🥁 Served in a Flask 🎸: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @talkpython@fosstodon.org X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @mkennedy@fosstodon.org Michael on X.com: @mkennedy

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Hosts & Guests

About

Talk Python to Me is a weekly podcast for Python developers, data scientists, and AI builders, hosted by developer and entrepreneur Michael Kennedy. We dive deep into the packages, tools, and people shaping Python, from web development and data science to AI and LLMs. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from its leaders. And if you've been Pythoning for years, you'll hear about your favorite packages and the hot new ones coming out of open source.

Information

  • Creator
    Michael Kennedy
  • Years Active
    2015 - 2026
  • Episodes
    564
  • Rating
    Clean
  • Copyright
    © Copyright 2015-2026
  • Show Website
    Talk Python To Me

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