Infectious Disease Puscast

Vincent Racaniello
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  • NATURAL SCIENCES
  • EVERY TWO WEEKS

A review of the infectious diseases literature from the previous two weeks.

  1. 2 HR AGO

    Infectious Disease Puscast

    On episode #101 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 2/12 – 2/25/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Impact of Proviral-DNA M184V/I on 96-Week Outcomes of DTG/3TC Maintenance Therapy: Results From the VOLVER Clinical Trial (CID) Tecovirimat for the Treatment of Mpox (NEJM) Bacterial Multicounty Outbreak of Salmonella Agbeni Linked to Ice in a Cooler at a County Fair — Illinois, August 2024 (CDC: MMWR) Legionella Pneumonia in the Modern Era: Clinical Features and Predictors of Mortality (CID) Cefalexin use in UK acute pyelonephritis practice: unaddressed challenges in dosing, breakpoints and clinical evidence (Journal of Antimicrobial Chemotherapy) Is three really what we need? Relative effectiveness of benzathine penicillin G and doxycycline treatment regimens for late or unknown duration syphilis in 6 United States jurisdictions, 2016–2021 (CID) Show Me the "Mino:" In Vitro Efficacy of Minocycline on Clinical Gram-Negative Bacterial Isolates (Microbial Drug Resistance) Initial Vancomycin Taper for the Prevention of Recurrent Clostridioides difficile Infection (JAMA Network) Microbial Flora in War Wounds from the Ukrainian Front Line (NEJM) Fungal The Last of US Season 2 (YouTube) Epidemiology of Aspergillosis Diagnoses in U.S. Adults using a National EHR Database, 2013-2023 (OFID) Parasitic State-of-the-Art Review: Chagas Disease—an Enduring Challenge (CID) Autochthonous Rat Lungworm Angiostrongylus cantonensis Infections in Accidental and Definitive Hosts, San Diego, California, USA (Emerging Infectious Diseases) Miscellaneous Ancient bacteria strain discovered in ice cave is resistant to some modern antibiotics(CNN) First genome sequence and functional profiling of Psychrobacter SC65A.3 preserved in 5,000-year-old cave ice: insights into ancient resistome, antimicrobial potential, and enzymatic activities (Frontiers in Microbiology) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    44 min

  2. 18 FEB

    Infectious Disease Puscast

    On episode #100 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/29/26 – 2/11/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis (PNAS) Dengue Suppression by Male Wolbachia-Infected Mosquitoes (NEJM) Assessing the impact of SARS-CoV-2 infection and vaccination on fertility and assisted reproductive techniques outcomes: an umbrella review (Vaccine) Prevalence of CSF HIV VIRAL Escape and Associations With Neurocognitive Outcomes Among HIV-Associated Meningitis Survivors: A Cohort Study (OFID) Adenoviral Inciting Antigen and Somatic Hypermutation in VITT (NEJM) Bacterial Extraintestinal Invasive Escherichia coli Infections in the US (JAMA Network OPEN) Clinical Manifestations, Long-Term Trends, and Risk Factors for Treatment Failure in Native Vertebral Osteomyelitis: A 26-Year Mayo Clinic Experience (CID) US Emergency Department Visits forAntibiotic Adverse Drug Events in Children, 2019-2023 (Journal of the Pediatric Infectious Diseases Society) Fungal The Last of US Season 2 (YouTube) Albumin orchestrates a natural host defence mechanism against mucormycosis (Nature) Pseudo-Outbreak of Purpureocillium lilacinum Skin Infections at a Dermatology Clinic — Washington, 2024 (CDC: MMWR) Candida auris Testing by the Antimicrobial Resistance Laboratory Network, United States, 2022–2023 (Emerging Infectious Diseases) Parasitic Trichinellosis: A zoonosis that still requires vigilance (PLoS Neglected Tropical Diseases) Trichinellosis after Raw Bear Eyeball Consumption (AJTMH: American Journal of Tropical Medicine and Hygiene) Moving Scabies Under Video-Dermoscopy (AJTMH: American Journal of Tropical Medicine and Hygiene) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    38 min

  3. 3 FEB

    Infectious Disease Puscast

    On episode #99 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/15/26 - 1/28/26. Host: Daniel Griffin and Sarah Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Symptomatic and asymptomatic norovirus infections in early life; The PREVAIL Cohort, 2017-2020 (CID) Bacterial Xenodiagnosis to search for Borrelia burgdorferi after antibiotic treatment of Lyme disease: a prospective cohort study (CID) Diagnostic Yield of Repeat Blood Cultures and Risk Factors for Bloodstream Infection in Persistent Febrile Neutropenia (CID) Methodology Misrepresented: Correcting the Record on the ATS Community-acquired Pneumonia Guideline Process (CID) Pediatric Infectious Diseases Physicians' Preferences for Management of Clostridioides difficile Infection: An Emerging Infections Network Surve (Journal of the Pediatric Infectious Diseases Society) Antibiotic Therapy for Uncomplicated AcuteAppendicitis (JAMA) Fungal The Last of US Season 2 (YouTube) Persistence of Symptoms among Commercially Insured Patients with Coccidioidomycosis, United States, 2017–2023 (CDC: Emerging Infectious Diseases) Ophthalmologic evaluation and clinical outcome in candidemia: a seven-year retrospective multicenter cohort study (OFID) Parasitic Postinfectious Syndromes and Long-Term Sequelae after Giardia Infections (CDC: Emergining Infectious Diseases) Priced Out of Treatment: The Exorbitant Cost of Antiparasitic Drugs in the United States (OFID) Miscellaneous All About the AAP Recommended Immunization Schedule (healthychildren.org) Recommended Childhood and Adolescent Immunization Schedule: United States, 2026: Policy Statement (American Academy of Pediatrics: Pediatrics) Feeling the Vibes: An Investigation into Resident Antibiotic Prescribing Practices (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    40 min

  4. 20 JAN

    Infectious Disease Puscast

    On episode #98 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 1/1/26 – 1/14/26. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Rhinovirus-Associated Lower Respiratory Tract Infection in Hospitalized Adult Patients: A Retrospective Cohort Study (JID) Demise of the Milwaukee Protocol for Rabies (CID) Reply to Willoughby on Demise of the Milwaukee Protocol for Rabies (CID) Bacterial Clinical Practice Guideline by Infectious Diseases Society of America (IDSA): 2025 Guideline on Management and Treatment of Complicated Urinary Tract Infections: Introduction and Methods (CID) Reassessing the 2023 International Society for Cardiovascular Infectious Diseases Duke clinical criteria for infective endocarditis: Impact of excluding fever and updating diagnostic definition (CID) The diagnostic accuracy of procalcitonin for community-acquired bacteremia: an updated systematic review and meta-analysis (CMI: Clincal Microbiology and Infection) Noninferiority of One HPV Vaccine Dose to TwoDoses (NEJM) About the wastewater program (Colorado: Department of Public & Environment) Notes from the Field: Wastewater Surveillance for Measles Virus During a Measles Outbreak — Colorado, August 2025 (CDC: MMWR) Notes from the Field: Retrospective Analysis of Wild-Type Measles Virus in Wastewater During a Measles Outbreak — Oregon, March 24–September 22, 2024 (CDC:MMWR) Fungal The Last of US Season 2 (YouTube) Candidozyma auris (formerly Candida auris): Resistant, long-lasting, and everywhere (CMI: Clincal Microbiology and Infection) Long-range air dispersal as an important source of environmental contamination in Candida auris clustering: possible infection control implication (Infection Control & Hospital Epidemiology) Parasitic Dermlite Dermatoscopes (dermatoscopes.com) Oral ivermectin versus 5% permethrin cream to treat children and adults with classic scabies: multicentre, assessor blinded, cluster randomised clinical trials (BMJ) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    27 min

  5. 6 JAN

    Infectious Disease Puscast

    On episode #97 of the Infectious Disease Puscast, Daniel reviews the infectious disease literature for the weeks of 12/18/25 – 12/31/25. Host: Daniel Griffin Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Outcomes Related to Bacterial Co-Infection and Antibiotic Use in Adults Hospitalized With Respiratory Syncytial Virus Compared with Influenza (OFID) Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 (Annals of Internal Medicine) Bacterial GeoSentinel Analysis of Travelers' Diarrhea Antimicrobial Resistance Patterns (JAMA Open Network) Rapid direct disk diffusion testing for antibiotic resistance in urinary tract infections: a bacterial concentration-adjusted approach (Microbiology Spectrum) Impact of an Educational Leaflet About Asymptomatic Bacteriuria and Urinary Tract Infection on Antibiotic Preferences Among US Adults ≥65 Years: An Online Randomized Controlled Survey Experiment (OFID) Fungal The Last of US Season 2 (YouTube) Real-world Evaluation of Histoplasmosis Diagnosis and Treatment in Patients From a Michigan Health System (OFID) Parasitic Progress Toward Eradication of Dracunculiasis (Guinea Worm Disease) — Worldwide, January 2024–June 2025 (CDC: MMWR) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    22 min

  6. 23/12/2025

    Infectious Disease Puscast #96

    On episode #96 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 12/4/25 – 12/17/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Rabies Cluster Among Steer on a Dairy Farm — Minnesota, 2024 (CDC:MMWR) Incidence of community-acquired pneumonia and herpes zoster in people with HIV based on CD4-count and age in the current antiretroviral therapy era: a longitudinal cohort study (CID) Associations between antibiotic use and outcomes in patients hospitalized with community-acquired pneumonia and positive respiratory viral assays (CID) Bacterial Lactobacillus Bacteremia: A Challenging Condition for Pediatrician (Pediatric Infectious Disease Journal) Trial of High-Dose Oral Rifampin in Adults with Tuberculous Meningitis (NEJM) Zoliflodacin versus ceftriaxone plus azithromycin for treatment of uncomplicated urogenital gonorrhoea: an international, randomised, controlled, open-label, phase 3, non-inferiority clinical trial (LANCET) Fungal The Last of US Season 2 (YouTube) Compassionate Use of Olorofim for Invasive Mold Infections: A Nationwide Observational Study in France  (OFID) Parasitic Eliminating Guinea worm (LANCET: Infectious Disases) Balamuthia mandrillaris Encephalitis in a 12-Year-old Girl: Report of the First Case Diagnosed in Greece (Pediatric Infectious Disease Journal) A Prospective Cohort Longitudinal Study of Human Acute Babesiosis: Quality of Life and Severity of Symptoms Through 1-Year Follow-up (OFID) Body lice and scabies co-infestation among unsheltered migrants, refugees, and asylum seekers and the right to water and sanitation (PLoS Neglected Tropical Diseases) Miscellaneous H.U.S.T.L.E: A Consult Fitness Guide for Infectious Diseases Providers (CID) Seven alternatives to evidence based medical education: an exploration of how we actually teach (BMJ) What does a doctor look like?Asking AI (BMJ) The Receding Specialty of Infectious Diseases and Implications for U.S. Healthcare (OFID) Integrating a host biomarker with a large language model for diagnosis of lower respiratory tract infection (Nature Communications) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    39 min

  7. 09/12/2025

    Infectious Disease Puscast

    On episode #95 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/20/25 – 12/3/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Early low-dose dexamethasone is associated with shorter acute symptom duration in Chikungunya virus infection: a retrospective cohort study (BMC Infectious Diseases) Noninferiority of One HPV Vaccine Dose to Two Doses (NEJM) Evidence to Action — Single-Dose HPV Vaccination and Cervical HPV Infection (NEJM) Daily Mosnodenvir as Dengue Prophylaxis in a Controlled Human InfectionModel (NEJM) Universal Hepatitis B Vaccination at Birth—Risks of Revising the recommendation (JAMA) Correlates of HIV-1 control after combination immunotherapy (Nature) Human-to-Human Rabies Transmission via Solid Organ Transplantation from a Donor with Undiagnosed Rabies — United States, October 2024–February 2025 (CDC: MMWR) Cytomegalovirus-specific cell-mediated immunity for prediction of post-prophylaxis CMV disease in a phase 3 trial of letermovir vs valganciclovir prophylaxis in donor CMV-seropositive recipient CMV-seronegative kidney transplant recipients (CID) An Analysis of Cytomegalovirus-Specific Cell-Mediated Immunity in a Phase 3, Randomized, Placebo-Controlled Trial of Letermovir Prophylaxis in Cytomegalovirus-Seropositive Recipients of an Allogeneic Hematopoietic Cell Transplant (CID) Bacterial Infectious Diseases Society of America (IDSA) Position Statement: Why IDSA Did Not Endorse the Community-Acquired Pneumonia Guidelines 2025 Update (CID) Lyme DiseaseIncidence in Massachusetts, 2012-2024 (JAMA: Open Network) Fungal The Last of US Season 2 (YouTube) Aspergillosis-Attributable Mortality in the United States: Analysis of Death CertificateData (CID) Oral itraconazole versus oral voriconazole for treatment-naive patients with chronic pulmonary aspergillosis in India (VICTOR-CPA trial): a single-centre, open-label, randomised, controlled, superiority trial (LANCET: Infectious Diseases) Parasitic Loa loa encephalopathy following treatment with benzimidazole derivatives: A systematic review (OFID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    43 min

  8. 25/11/2025

    Infectious Disease Puscast

    On episode #94 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 11/11/25 – 11/19/25. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Epstein-Barr virus reprograms autoreactive B cells as antigen-presenting cells in systemic lupus erythematosus (Science Translational Medicine) Hepatitis B reactivation following switch away from tenofovir-containing anti-retroviral therapy in people living with HIV: A case series and lessons for practice (CID) Antimicrobial drug-resistant Neisseria gonorrhoeae (GC) infections in men using doxycycline postexposure prophylaxis. A substudy of the ANRS 174 DOXYVAC trial (CID) HIV Pre-exposure Prophylaxis Does Not Increase Gonorrhea and Chlamydia Incidence in Young Black and Hispanic Men who Have Sex With Men: An Observational Cohort Study (OFID) Bacterial Global and regional knowledge of antibiotic use and resistance among the general public: a systematic review and meta-analysis (CMI: Clinical Microbiology and Infection) Infant Botulism Outbreak Linked to Infant Formula, November 2025 (CDC: Botulism) Outbreak Investigation of Infant Botulism: Infant Formula (November 2025) (FDA) Vitamin D deficiency at hospital admission with community-acquired pneumonia is associated with increased risk of mortality: A Prospective Cohort Study (OFID) Bat-Associated Hemotropic Mycoplasmas in Immunosuppressed Children, Spain, 2024 (Emerging Infectious Diseases) A Multicomponent Intervention to Improve Maternal Infection Outcomes (NEJM) Fungal The Last of US Season 2 (YouTube) Increasing Fluconazole Resistance in Candida parapsilosis: A 10-Year Analysis of Blood Culture Isolates at a US Reference Laboratory (2015–2024) (JID) British Society for Medical Mycology best practice recommendations for the diagnosis of serious fungal diseases: 2025 update (LANCET: Infectious Diseases) In Vivo Evolution of Candida auris Multidrug Resistance in a Patient Receiving Antifungal Treatment (JID) Parasitic Implications of a fatal anaphylactic reaction occurring 4 hours after eating beef in a young man with IgE antibodies to galactose-α-1,3-galactose (JACI: Journal of Allergy and Clinical Immunology In practice) WHO recommends R21/Matrix-M vaccine for malaria prevention in updated advice on immunization (WHO) Effectiveness of the RTS,S/AS01E malaria vaccine in a real-world setting over 1 year of follow-up after the three-dose primary schedule: an interim analysis of a phase 4 study in Ghana, Kenya, and Malawi (LANCET: Global Health) A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication? (PLoS Neglected Tropical Diseases) Miscellaneous IL12RB1 deficiency appearing in North America: expanding the clinical phenotypes (CID) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

    46 min
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A review of the infectious diseases literature from the previous two weeks.

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