The a16z Show

a16z
a16z

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

  1. 12 hr ago

    What It Takes to Build a Startup | Andrew Chen & Matt Perault

    a16z’s Matt Perault sits down with General Partner and Speedrun lead Andrew Chen on the a16z AI Policy Brief to explore what “Little Tech” actually looks like at the earliest stages, and why the realities of building a two- or three-person startup are often missing from policy debates. Andrew takes us inside Speedrun, where founders are often starting companies from kitchen tables, working with tiny teams, and trying to determine in a matter of months whether their idea can become a viable business. He explains why these founders rarely have the time or resources to engage with policymakers, even as regulation can have an outsized impact on whether and where they build. Matt and Andrew also discuss how regulatory burdens accumulate for young companies, why startups can choose where to put down roots, the role of ecosystems like Tech Week, and what policymakers can do to hear directly from the founders who may otherwise be absent from the conversation. This episode originally appeared on the a16z AI Policy Brief.   Resources: Follow Andrew Chen on X: https://x.com/andrewchen Follow Matt Perault on X: https://x.com/MattPerault Learn more about a16z Speedrun: https://speedrun.a16z.com Listen to more from the a16z AI Policy Brief: https://a16zpolicy.substack.com/  Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

  2. 1 day ago

    How AI Is Rewriting the Power Law of Venture Capital

    a16z’s Jen Kha and David George sit down with Accolade Partners’ Aram Verdiyan to discuss how AI is changing the power law of technology investing, why the largest companies can compound advantages in ways that weren’t possible before, and what that means for how investors construct portfolios. They explore why AI may be much bigger than traditional software, with applications reaching into labor, healthcare, transportation, services, and other major parts of the economy. David explains why capital itself can now reinforce an AI company’s advantage by buying more compute, while Aram makes the case that AI should increasingly be treated as a core allocation rather than a satellite position. The conversation also gets into the changing economics of venture and growth investing, how to distinguish real AI traction from early hype, what AI means for legacy software and private equity, and why some of the largest opportunities may still be ahead in robotics, autonomy, healthcare, energy, and physical infrastructure. Resources: Follow Aram Verdiyan on X: https://x.com/aramverdi Follow Jen Kha on X: https://x.com/jkhamehl Follow David George on X: https://x.com/DavidGeorge83   Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

  3. 2 days ago

    Who Grades the AI Models? | Ben Horowitz & Rayan Krishnan

    a16z’s Erik Torenberg, Ben Horowitz, and Jennifer Li sit down with Vals founder and CEO Rayan Krishnan to discuss one of AI’s increasingly difficult problems: how do you actually measure whether a model is getting better? As public benchmarks saturate and models get better at optimizing for the tests themselves, Rayan makes the case for independent, continuously evolving evaluations. They unpack why self-reported model scores can be misleading, how VALS evaluates models in the hours before a release, and why measuring increasingly agentic systems means testing work that can unfold over hours, days, or even weeks. They also explore why evals are becoming critical for enterprises trying to understand the ROI of AI, what happens if token spend begins to rival employee salaries, and how evaluations could eventually provide a shared language for everything from model routing and recursive self-improvement to AI policy and international coordination. Resources: Follow Rayan Krishnan on X: https://x.com/RayanKrishnan Follow Ben Horowitz on X: https://x.com/bhorowitz Follow Jennifer Li on X: https://x.com/JenniferHli  Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

  4. 3 days ago

    OpenAI Researchers on the Future of Mathematical Reasoning

    a16z Infra Partner Lisha Li sits down with OpenAI mathematicians Mehtaab Sawhney and Mark Sellke to discuss how quickly AI’s mathematical capabilities are advancing, what recent results reveal about model reasoning, and what happens when AI begins making progress on problems mathematicians have struggled with for decades. Mehtaab and Mark unpack several recent results from OpenAI’s models, including advances in sphere packing and the construction of a non-sofic group. They explain why the surprising part isn’t simply that models can search more possibilities or work longer than humans: in many cases, the reasoning traces look remarkably similar to the work of an expert mathematician, including choosing promising approaches, backtracking when they fail, and combining ideas from across the literature. They also explore what this means for mathematics itself: how the role of human taste and judgment may change, whether AI could produce far more mathematics than humans can absorb, and why models that accelerate discovery may also make sophisticated results easier to understand. Resources: Follow Lisha Li on X: https://x.com/lishali88 Follow Mehtaab Sawhney on X: https://x.com/mehtaab_sawhney Follow Mark Sellke on X: https://x.com/MarkSellke Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

  5. 4 days ago

    Can Open Source Keep AI Power From Concentrating?

    MTS host Sophia Dew visits the Open Source AI Summit in San Francisco to ask researchers and founders across the AI stack a central question: can open source prevent AI power from concentrating in the hands of a few companies? Lukasz Kaiser, co-author of Attention Is All You Need, argues that today’s concentration may be a feature of the current technological paradigm rather than a permanent feature of AI. Transformers reward enormous amounts of data and compute, but future breakthroughs could make smaller, more specialized models far more capable. Across conversations with researchers and builders working on open models, infrastructure, and applications, Sophia explores why China has taken the lead in open-weight models, whether the U.S. needs more open-model startups, what it means for companies to own their own intelligence, and where openness alone falls short, particularly when access to compute remains concentrated.   Resources: Follow Lukasz Kaiser on X: https://x.com/lukaszkaiser Follow Sophia Dew on X: https://x.com/sophiadew Follow MTS on X: https://x.com/mtslive   Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

  6. 5 days ago

    Your AI Doctor Is Coming | Julie Yoo

    a16z General Partner Julie Yoo joins MTS host Sophia Dew to explain why she believes healthcare could benefit more from AI than almost any other industry, and why decades of slow technology adoption may actually give healthcare an advantage in the AI era. Julie traces healthcare’s evolution from paper records and fax machines through electronic health records and telehealth, and explains why AI represents something different: an organic adoption wave driven by tools that doctors and patients actually want to use. Because healthcare never built the same layers of legacy software as other industries, it may now be able to leapfrog directly into agentic AI. They also explore how AI could dramatically lower the cost of care, why consumers are becoming a more important payer, where Julie sees the biggest opportunities for healthcare founders, and a future where everyone has a highly personalized AI doctor in their pocket for life. Resources: Follow Julie Yoo on X: https://x.com/julesyoo Follow Sophia Dew on X: https://x.com/sophiadew Follow MTS on X: https://x.com/mtslive   Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

  7. 6 days ago

    Aaron Levie on Why Open AI Wins

    Box co-founder and CEO Aaron Levie joins MTS hosts Theo Jaffee and Sofia Puccini to make the case for open-weight AI, unpack the economics of open versus closed models, and explain why he believes more openness could strengthen rather than undermine the U.S. AI ecosystem. Aaron argues that open models create more use cases, push closed labs to innovate faster, and don't fundamentally change where the economics of AI ultimately accrue. They debate model distillation, America's competition with China, why restricting access may simply accelerate competing AI ecosystems, and whether U.S. labs should begin releasing open-weight versions of previous-generation models. They also get into what the latest frontier models mean for knowledge work, how AI has changed software engineering at Box, and why Aaron believes companies cutting engineers may simply not be ambitious enough. Finally, they discuss why enterprises are unlikely to bet on a single model and why the layer that routes between models, data, and workflows could become increasingly valuable.   Resources: Follow Aaron Levie on X: https://x.com/levie Follow Theo Jaffee on X: https://x.com/theojaffee Follow Sofia Puccini on X: https://x.com/schisofrenia Follow MTS on X: https://x.com/mtslive  Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

  8. 4 Sept

    Fei Fei Li: The Race to Build World Models For AI

    World Labs co-founders Fei-Fei Li, Justin Johnson, and Ben Mildenhall join a16z General Partner Martin Casado to discuss Atlas, their latest world model, and what it reveals about the pursuit of spatial intelligence. At the center of Atlas is what the team calls “new view prediction”: given images or views of a scene, the model predicts what that environment should look like from a different position in space and time. This brings generation and 3D reconstruction into the same model, and raises a broader question about whether predicting views could become a useful primitive for understanding the physical world. They discuss the technical bets behind the model, what it can and can’t yet capture, and the importance of dynamics, editability, and simulation as world models develop. The conversation also explores applications in creative work, architecture, and robotics, where Fei-Fei argues that one of today’s biggest constraints is access to real-world training data.   Resources: Follow Fei-Fei Li on X: https://x.com/drfeifei Follow Justin Johnson on X: https://x.com/jcjohnss Follow Ben Mildenhall on X: https://x.com/BenMildenhall Follow Martin Casado on X: https://x.com/martin_casado Learn more about Atlas: https://www.worldlabs.ai/blog/atlas   Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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About

The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!

Information

  • Channel
    a16z
  • Creator
    Andreessen Horowitz
  • Years Active
    2014 - 2026
  • Episodes
    1k
  • Rating
    Clean
  • Copyright
    © All rights reserved
  • Show Website
    The a16z Show

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