Medscape InDiscussion: Obesity Medscape

Drs Robert Kushner and obesity pharmacotherapy expert Ania Jastreboff discuss how to use the new obesity medications effectively in clinic. Tune in to hear expert recommendations on patient communication, side effects, and more.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982636). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Obesity Treatment & Management https://emedicine.medscape.com/article/123702-treatment
Drugs for Treating Obesity https://pubmed.ncbi.nlm.nih.gov/34783910/
Control-Theory Models of Body-weight Regulation and Body-weight-regulatory Appetite https://pubmed.ncbi.nlm.nih.gov/31494154/
Obesogenic Environments: Current Evidence of the Built and Food Environments https://pubmed.ncbi.nlm.nih.gov/28449616/
FDA-approved Pharmacotherapy for Weight Loss Over the Last Decade https://pubmed.ncbi.nlm.nih.gov/36277516/
Tirzepatide https://pubmed.ncbi.nlm.nih.gov/36251836/
New Frontiers in Obesity Treatment: GLP-1 and Nascent Nutrient-Stimulated Hormone-Based Therapeutics https://pubmed.ncbi.nlm.nih.gov/36706749/
Once-Weekly Semaglutide in Adults With Overweight or Obesity https://pubmed.ncbi.nlm.nih.gov/34192447/
Tirzepatide Once Weekly for the Treatment of Obesity https://pubmed.ncbi.nlm.nih.gov/35658024/
Bariatric Surgery https://emedicine.medscape.com/article/197081-overview
FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014 https://www.fda.gov/news-events/press-announcements/fda-approves-new-drug-treatment-chronic-weight-management-first-2014
Body Mass Index https://medlineplus.gov/ency/article/007196.htm
Descriptive Analysis of Reported Adverse Events Associated With Anti-obesity Medications Using FDA Adverse Event Reporting System (FAERS) Databases 2013-2020 https://pubmed.ncbi.nlm.nih.gov/34564826/
Antiobesity Drug Therapy: An Individualized and Comprehensive Approach https://pubmed.ncbi.nlm.nih.gov/34341028/
Barriers and Solutions for Prescribing Obesity Pharmacotherapy https://pubmed.ncbi.nlm.nih.gov/32418592/
Addressing Insurance-related Barriers to Novel Antiobesity Medications: Lessons to Be Learned From Bariatric Surgery https://pubmed.ncbi.nlm.nih.gov/36190393/
Certifying Physicians in the Treatment of Obesity https://www.abom.org/

Diabetes and obesity are on the rise, and there are new tools to help the prevention and management of this twin epidemic of "diabesity" in primary care. Drs Robert Kushner and Tim Garvey discuss.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982635). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Obesity Treatment & Management https://emedicine.medscape.com/article/123702-treatment
Type 2 Diabetes Mellitus https://emedicine.medscape.com/article/117853-overview
Diabesity https://diabetesjournals.org/clinical/article/40/4/392/147743/Diabesity
National Diabetes Statistics Report: Estimates of Diabetes and Its Burden in the United States https://www.cdc.gov/diabetes/data/statistics-report/index.html
Prevalence of Diabetes by Race and Ethnicity in the United States, 2011-2016 https://pubmed.ncbi.nlm.nih.gov/31860047/
Trends in Prevalence of Type 1 and Type 2 Diabetes in Children and Adolescents in the US, 2001-2017 https://pubmed.ncbi.nlm.nih.gov/34427600/
CDC Diabetes and Obesity Maps https://www.cdc.gov/diabetes/data/center/slides.html
Diabetes Technology: Standards of Care in Diabetes – 2023 https://pubmed.ncbi.nlm.nih.gov/36507635/
American Association of Clinical Endocrinology Clinical Practice Guideline: Developing a Diabetes Mellitus Comprehensive Care Plan – 2022 Update https://pubmed.ncbi.nlm.nih.gov/35963508/
Mediterranean Diet and Obesity-Related Disorders: What Is the Evidence? https://pubmed.ncbi.nlm.nih.gov/36178601/
The Look AHEAD Study: A Description of the Lifestyle Intervention and the Evidence Supporting It https://pubmed.ncbi.nlm.nih.gov/16855180/
Durability of a Primary Care–Led Weight-Management Intervention for Remission of Type 2 Diabetes: 2-Year Results of the DiRECT Open-Label, Cluster-Randomised Trial https://pubmed.ncbi.nlm.nih.gov/30852132/
Semaglutide https://reference.medscape.com/drug/ozempic-rybelsus-wegovy-semaglutide-1000174
Liraglutide https://reference.medscape.com/drug/victoza-saxenda-liraglutide-999449
Tirzepatide Once Weekly for the Treatment of Obesity https://pubmed.ncbi.nlm.nih.gov/35658024/
Glucagon-Like Peptide 1 Receptor Agonists https://www.ncbi.nlm.nih.gov/books/NBK551568/
Dulaglutide Injection https://medlineplus.gov/druginfo/meds/a614047.html
Sodium-Glucose Transport Protein 2 (SGLT2) Inhibitors https://www.ncbi.nlm.nih.gov/books/NBK576405/
Incretin Hormones: Their Role in Health and Disease https://pubmed.ncbi.nlm.nih.gov/29364588/
Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Antagonists as Anti-Diabetic Agents https://pubmed.ncbi.nlm.nih.gov/29412817/

How do you medically evaluate a person who presents with obesity? Drs Robert Kushner and Amanda Velazquez share practical tools and pearls for community clinicians.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982633). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Obesity Treatment & Management https://emedicine.medscape.com/article/123702-treatment
A Primer on Smoking Cessation in Primary Care https://www.medscape.com/viewarticle/864524_3
Reasons for Underutilization of Bariatric Surgery: The Role of Insurance Benefit Design https://pubmed.ncbi.nlm.nih.gov/30425002/
Antiobesity Drug Therapy: An Individualized and Comprehensive Approach https://pubmed.ncbi.nlm.nih.gov/34341028/
Taking a Weight History – Using Mnemonics to Learn a Missing Skill in Medical Education [Version 1] https://mededpublish.org/articles/6-215
The Broadening Domain of the Metabolic Syndrome https://www.medscape.org/viewarticle/508282
Mallampati Classification https://emedicine.medscape.com/article/2172419-overview
Acanthosis Nigricans https://emedicine.medscape.com/article/1102488-overview
Cushing's Syndrome https://www.niddk.nih.gov/health-information/endocrine-diseases/cushings-syndrome
Clinical Use of the Edmonton Obesity Staging System for the Assessment of Weight Management Outcomes in People With Class 3 Obesity https://pubmed.ncbi.nlm.nih.gov/35267942/
The Progression of Cardiometabolic Disease: Validation of a New Cardiometabolic Disease Staging System Applicable to Obesity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866217/
Modern Epigenetics Methods in Biological Research https://pubmed.ncbi.nlm.nih.gov/32645449/

Need practical advice on setting up your office to provide nonstigmatized, comfortable, and effective obesity care? Drs Robert Kushner and Scott Kahan are here to help.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982632). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources: Obesity Treatment & Management https://emedicine.medscape.com/article/123702-treatment
Medscape Diabetes & Endocrinology Decision Point https://decisionpoint.medscape.com/diabetes-endocrinology?type=Metabolic%20Disorders&subtype=Obesity
Adult Obesity Facts https://www.cdc.gov/obesity/data/adult.html
Certifying Physicians in the Treatment of Obesity https://www.abom.org/
The Chronic Care Model: Description and Application for Practice https://www.medscape.com/viewarticle/549040_3
Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity https://pubmed.ncbi.nlm.nih.gov/36622115/
Patient-centered Medical Home (PCMH) Model https://www.cdc.gov/dhdsp/policy_resources/pcmh.htm
A Review of Current Guidelines for the Treatment of Obesity https://pubmed.ncbi.nlm.nih.gov/36525676/
Obesity Canada https://obesitycanada.ca/guidelines/chapters/
AGA Clinical Practice Guideline on Pharmacological Interventions for Adults With Obesity https://pubmed.ncbi.nlm.nih.gov/36273831/

How can you change the paradigm on obesity as a disease? In this episode, Drs Robert Kushner and Donna Ryan dig into the science, speak about bias within the healthcare system, and advocate for better patient care.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982631). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Comparison of Weight-Loss Diets With Different Compositions of Fat, Protein, and Carbohydrates https://pubmed.ncbi.nlm.nih.gov/19246357/
Look AHEAD (Action for Health in Diabetes): Design and Methods for a Clinical Trial of Weight Loss for the Prevention of Cardiovascular Disease in Type 2 Diabetes https://pubmed.ncbi.nlm.nih.gov/14500058/
First versus Repeat Treatment With a Lifestyle Intervention Program: Attendance and Weight Loss Outcomes https://pubmed.ncbi.nlm.nih.gov/18711387/
Effects of Dietary Patterns on Blood Pressure: Subgroup Analysis of the Dietary Approaches to Stop Hypertension (DASH) Randomized Clinical Trial https://pubmed.ncbi.nlm.nih.gov/9989541/
The Role of Gut Hormones in Diet-Induced Weight Change: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/28934819/
Adult Obesity Facts https://www.cdc.gov/obesity/data/adult.html
Obesity Emergence in the Pacific Islands: Why Understanding Colonial History and Social Change Is Important https://pubmed.ncbi.nlm.nih.gov/25166024/
The Prevalence of Overweight and Obesity in an Adult Kuwaiti Population in 2014 https://pubmed.ncbi.nlm.nih.gov/31338067/
Obesity in Mexico, Prevalence and Trends in Adults. Ensanut 2018-19. https://pubmed.ncbi.nlm.nih.gov/33620965/

Join Dr Robert Kushner and Joe Nadglowski, CEO of the Obesity Action Coalition, for a discussion on how weight-based bias and stigma harm patients living with obesity, and how you can help.
Relevant disclosures can be found with the episode show notes on Medscape (https://www.medscape.com/viewarticle/982630). The topics and discussions are planned, produced, and reviewed independently of advertisers. This podcast is intended only for US healthcare professionals.
Resources
Obesity Action Coalition https://www.obesityaction.org/
Joint International Consensus Statement for Ending Stigma of Obesity https://pubmed.ncbi.nlm.nih.gov/32127716/
Michigan Department of Civil Rights https://www.michigan.gov/mdcr/for-victims-of-unlawful-discrimination
Income Inequality and Obesity Among US Adults 1999-2016: Does Sex Matter? https://pubmed.ncbi.nlm.nih.gov/34281016/
Prevalence of Obesity Among Adults, by Household Income and Education - United States, 2011-2014 https://pubmed.ncbi.nlm.nih.gov/29267260/
Weight Bias and Stigma: Impact on Health https://pubmed.ncbi.nlm.nih.gov/34749889/
Project Implicit https://implicit.harvard.edu/implicit/takeatest.html
Weight Bias Internalization and Health: A Systematic Review https://pubmed.ncbi.nlm.nih.gov/29788533/