The Stem Cell Podcast

The Stem Cell Podcast

A podcast dedicated to culturing knowledge in stem cell research. Brought to you by STEMCELL Technologies.

  1. 1月20日

    Ep. 312: “Biomanufacturing in Space” Featuring Dr. Pinar Mesci

    Guest: Dr. Pinar Mesci is the Global Head of Biomanufacturing and Biotechnology at Axiom Space, where she manages a portfolio focused on biomedical research programs including stem cells, tissue engineering, disease modeling, cancer research, and DNA-inspired nanomaterials. She talks about her early career developing brain organoid models, transitioning to the space industry, and how microgravity affects biological systems. She also discusses the future of low Earth orbit research and how new technologies can be transferred back to Earth. (40:55) Featured Products and Resources: Submit your abstract for ISSCR 2026 by February 25th! Take your human pluripotent stem cell cultures further with mTeSR™ Plus from STEMCELL Technologies. The Stem Cell Science Round Up iPSC-Derived Ovarian Support Cells – Fertilo is an ovarian support cell product that improves the in vitro maturation rate of human oocytes. (1:25) Culturing HSPCs Ex Vivo – A nanoengineered 3D system improves HSPC multi-lineage differentiation and engraftment capacity. (13:30) Spinal Core Repair Scaffolds – A nanoengineered extrusion-aligned tract promotes axonal reconnection, synapse formation, and locomotor recovery after spinal cord injury. (22:50) Vascularizing Retinal Organoids – Transient vascular support enhances survival of retinal ganglion cells in organoids. (32:14) Image courtesy of Dr. Pinar Mesci Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

    1 小時 28 分鐘
  2. 23/12/2025

    Ep. 311: “Congenital Heart Disease” Featuring Dr. Deepak Srivastava

    Guest: Dr. Deepak Srivastava is the President of the Gladstone Institutes and Director of the Roddenberry Stem Cell Center. His lab is focused on the gene networks that guide cardiac development. He talks about their recent work investigating heart defects in Down syndrome and strategies for delivering therapies to the heart. He also talks about how to incentivize the development and commercialization of cell and gene therapies. (41:50) Featured Products and Resources: Submit your abstract for ISSCR 2026! STEMdiff™ Ventricular Cardiomyocyte Differentiation Kit The Stem Cell Science Round Up Heart and Ganglion Development – Researchers fused human sympathetic ganglion organoids and heart-forming organoids to construct functional connections between the sympathetic ganglia and the heart. (2:38) Periportal Liver Assembloids – Patient-specific periportal liver assembloids retain the histological arrangement, gene expression, and cell interactions of periportal liver tissue. (9:40) PIEZO1 and Drug-Induced Cardiotoxicity – Restoring endothelial PIEZO1 protects against tyrosine kinase inhibitor-induced hypertension and cardiac dysfunction. (19:28) Somite and Neural Tube Co-Development – Scientists developed human trunk-like structures that have morphologically organized somites and a neural tube that form through self-organized, endogenous signaling. (28:43) Image courtesy of Dr. Deepak Srivastava Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

    1 小時 28 分鐘
  3. 28/10/2025

    Ep. 307: “Vascular Biology” Featuring Dr. Juan Melero-Martin

    Guest: Dr. Juan Melero-Martin is an Associate Professor and the Endowed Chair in Cardiac Surgery at Boston Children’s Hospital. His lab uses bioengineering principles to understand how vascular networks are formed and the mechanisms by which the vasculature modulates the engraftment and activity of various human stem cells. (42:03) Featured Products and Resources: Save time and stay current with ESC & iPSC News. Learn experimental procedures and laboratory techniques for life science research The Stem Cell Science Round Up Chromosomal Genes Linked to Heart Disease – Scientists identified HMGN1, a nuclear binding protein, as a key contributor to trisomy 21-related congenital heart defects. (1:46) Questioning Common Technique for Assessing IVF Embryos  – Live imaging of late-stage preimplantation human embryos suggests that abnormalities can arise at a later stage of development than previously thought. (14:14) Vitamin C Protects Ovaries – Scientists have shown that oral vitamin C protects against ovarian aging in primates. (24:07) Multi-Branching Cell Differentiation Trajectories – A new Hodge Laplacian model has advanced single-cell multimodal data analysis by providing highly reliable results for complex multi-branching trajectories. (33:58) Photo Reference: Courtesy of Dr. Juan Melero-Martin. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

    1 小時 37 分鐘

關於

A podcast dedicated to culturing knowledge in stem cell research. Brought to you by STEMCELL Technologies.

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