Change Your Mind with New Scientist

New Scientist

Change Your Mind from New Scientist brings you the brain health advice you really need to know. Every week, award‑winning science journalists Cat de Lange and Helen Thomson cut through wellness hype to find out what actually keeps your mind sharp, your mood steady and your memory strong. As friends, they’ve spent decades swapping stories, testing trends and exploring the latest neuroscience, and thought it was about time to share the tips and tricks that have genuinely changed their own lives. From cold plunges to coffee, supplements to sleep, Ozempic and AI they speak to leading experts and ask: does this really work?  Expect smart conversations, clear answers, and practical takeaways - with plenty of laughs along the way. Because when you understand your brain, you really can change your mind - for the better. New Episodes every Thursday. 

  1. 20 ago

    Ozempic: Could Weight-Loss Drugs have Surprising Brain Benefits?

    In this episode of Change Your Mind with New Scientist, Health Journalists Helen Thomson and Cat de Lange dive into the headline grabbing class of drugs behind the Ozempic boom to ask what these medications are really doing to our brains? Beyond weight loss and diabetes, early evidence hints at wide‑ranging effects on appetite, addiction, mood, and even long‑term brain health. With so many people now taking GLP‑1 agonists, are we unintentionally running the largest brain experiment in history, and what is it starting to reveal? To find out, they’re joined by Professor Paul Kenny, a leading expert on the brain’s reward and motivation systems. Together, they unpack how these drugs might quiet “food noise”, reshape our cravings, and potentially influence conditions like depression, alcohol use, and Alzheimer’s disease, while also confronting their cultural side effects, from shifting body ideals to questions about who really benefits.  Produced by Emily Bird Find out more about Ozempic and other GLP-1 Agonists at New Scientist: https://www.newscientist.com/article/2503480-the-potential-of-glp-1-drugs-to-transform-medicine-exploded-in-2025/ Sources: https://www.newscientist.com/article/2456669-why-do-ozempic-and-wegovy-seem-to-treat-everything/ https://www.newscientist.com/article/2464829-glp-1-drugs-like-ozempic-and-wegovy-lower-the-risk-of-42-conditions/ https://www.newscientist.com/article/2435246-the-surprising-mental-health-and-brain-benefits-of-weight-loss-drugs/ https://www.newscientist.com/article/2460806-well-learn-about-ozempics-potential-for-alzheimers-disease-in-2025/#:~:text=Two%20clinical%20trials%20investigating%20semaglutide,in%20treating%20this%20intractable%20condition.&text=Semaglutide%20belongs%20to%20a%20class,a%20hormone%20called%20GLP%2D1 https://www.theguardian.com/fashion/2025/oct/17/fashion-shows-fewer-plus-size-models-vogue-business

  2. 9 jul

    Smell - The Surprising Link Between Olfaction and Dementia

    Our sense of smell is often dismissed as our less important than sight and hearing, but what if it’s quietly shaping our memories, mood and long‑term brain health? In this episode, Health Journalists Helen Thomson and Cat de Lange explore the surprising brain superhighway between scent, emotion and memory, to explore why certain smells can yank you back to childhood and why smell could hold the key to healthy brain aging.  They are joined by neuroscientist Michael Leon, who explains what happens when we lose our sense of smell, and staggeringly that simply enriching your life with  pleasant scents could help protect you from diseases like Alzheimer’s. Produced by Emily Bird We want to hear your thoughts, leave a comment or send in your ideas for future episodes to ⁠⁠⁠⁠⁠changeyourmind@newscientist.com⁠⁠⁠ Find out more about your senses at New Scientist: ⁠https://www.newscientist.com/article-topic/senses/⁠  Learn more about our sponsor Alzheimer’s Society: ⁠⁠⁠⁠⁠⁠⁠https://www.newscientist.com/alzheimers-society/⁠⁠⁠⁠⁠⁠ Sources https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.15048  https://www.nature.com/articles/s41598-024-69772-y  https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1200448/full  https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/trc2.70120  https://onlinelibrary.wiley.com/doi/10.1111/ggi.14344  https://www.newscientist.com/article/2517205-if-a-drug-had-the-same-benefits-as-the-arts-wed-take-it-every-day/

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Change Your Mind from New Scientist brings you the brain health advice you really need to know. Every week, award‑winning science journalists Cat de Lange and Helen Thomson cut through wellness hype to find out what actually keeps your mind sharp, your mood steady and your memory strong. As friends, they’ve spent decades swapping stories, testing trends and exploring the latest neuroscience, and thought it was about time to share the tips and tricks that have genuinely changed their own lives. From cold plunges to coffee, supplements to sleep, Ozempic and AI they speak to leading experts and ask: does this really work?  Expect smart conversations, clear answers, and practical takeaways - with plenty of laughs along the way. Because when you understand your brain, you really can change your mind - for the better. New Episodes every Thursday.