This Week in Neuroscience Vincent Racaniello

TWiN reviews altered somatosensory reactivity, which is frequently observed among individuals with autism spectrum disorders (ASD), and in mouse models the developmental timing of aberrant touch processing can predict the manifestation of ASD-associated behaviors in mouse models. 
Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison
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Links for this episode MicrobeTV Discord Server Mouse models of autism spectrum disorder (Nature Neuroscience) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
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TWiN reviews experiments which show that SARS-CoV-2 triggers the up-regulation of synaptic components and perturbs local electrical field potential in cerebral organoids, organotypic culture of human brain explants and post-mortem brain samples from individuals with COVID-19. 
Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison
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Links for this episode MicrobeTV Discord Server SARS-CoV-2 perturbs synaptic homeostasis (Nature Micro) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv

TWiN welcomes mice to the elite club of ‘self-aware’ animals, with a study demonstrating a mirror-induced self-directed behavior in mice resembling visual self-recognition. 
Hosts: Vincent Racaniello, Timothy Cheung, and Vivianne Morrison
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Links for this episode MicrobeTV Discord Server Mice are self-aware (Neuron) Mirror self-recognition in mice (Neuron) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv

TWiN describes a study that reveals activation of endogenous retroviruses in oligodenroglia from patients with traumatic brain injury. 
Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung
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Links for this episode MicrobeTV Discord Server Activation of endogenous retroviruses in TBI oligodendroglia (Cell Rep) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv

TWiN explains an amazing study of a man who was paralyzed after a spinal cord injury and regained the ability to walk after implantation of a brain-spinal cord interface. 
Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung
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Links for this episode MicrobeTV Discord Server Walking naturally after spinal cord injury (Nature) The paralyzed rat that walked (YouTube) Mike the headless chicken (Wikipedia) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv

TWiN explains research showing that interaction between glioma cells and neurons in the brain shares mechanistic features with synaptic plasticity that contributes to memory and learning in the healthy brain. 
Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung
Subscribe (free): Apple Podcasts, Google Podcasts, RSS
Links for this episode MicrobeTV Discord Server Glioma synapses recruit mechanisms of adaptive plasticity (Nature) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees
Send your neuroscience questions and comments to twin@microbe.tv