Wissen schafft Macht. Macht aber nix. Oder? WISM²ANO Ein Podcast der BioteXpert*innen

Science Communication at acib GmbH

Worüber forscht die Wissenschaft – und was hat das mit unserem Alltag zu tun? Im Wissenschaftspodcast des Austrian Centre of Industrial Biotechnology (acib) kommen die BioteXpert*innen selbst zu Wort. Mit der neuen Staffel gehen wir tiefer rein, breiter raus – und manchmal auch thematisch quer: Wir sprechen über naturwissenschaftliche Themen mit Fokus auf Life Sciences und Biotechnologie, denken aber weiter – mit einem offenen Blick auf mögliche gesellschaftliche Auswirkungen. Wir diskutieren mit Fachleuten, spinnen Utopien – und Dystopien.

  1. Inside Piezo4Spine: The Challenge of Spinal Cord Repair

    19 jun

    Inside Piezo4Spine: The Challenge of Spinal Cord Repair

    What if a spinal cord injury never truly ends? Years after the accident, the body is still under pressure: chronic inflammation, recurring infections, and neurons that are alive—but unable to reconnect. In this episode, we take you inside Piezo4Spine, a European research project working on a radically different approach to spinal cord repair. In this episode Why “spinal cord injury” is not a single condition What happens in the body immediately after injury—and years later Why scar tissue becomes a major barrier to recovery How the immune system changes long-term What happens in the brain after losing input Why previous repair strategies have failed Piezo4Spine flips the perspective: Targeting scar-forming cells (fibroblasts) instead of only neuronsUsing nanoparticles for targeted drug deliveryDeveloping an implantable 3D “theramesh”Testing everything in preclinical animal models The idea: before reconnecting nerves, you need to fix the environment they live in. Guests: Dr. Juliana Martins da Rosa Neurophysiologist focusing on neural circuits and regeneration at the Hospital for Paraplegics in Toledo (Spain), SESCAM Dr. Elisa López Dolado Clinician-scientist specializing in spinal cord injury and rehabilitation at the Hospital for Paraplegics in Toledo (Spain), SESCAM More information: Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats Collagen-based scaffolds loaded with iron oxide nanoparticles promote functional sensorimotor recovery in spinal cord injury | bioRxivA regenerative rehabilitation strategy based on rGO scaffolds and treadmill training boosts neural, vascular and muscle repair features in chronic hemisected rats - ScienceDirect Follow the Piezo4Spine channels: LinkedIn Instagram

    43 min.
  2. The Disappearing Giant: Saving Pinna nobilis

    3 mrt

    The Disappearing Giant: Saving Pinna nobilis

    This episode takes us beneath the Mediterranean surface — into a broader field of science, where the tools and thinking we know from biotech meet ecology, disease research, and conservation biology. Pinna nobilis, the fan mussel, is the largest bivalve mollusc in the Mediterranean Sea. It has been known since antiquity: ancient Greek and Roman authors already described pinnae, and its fine anchoring threads — the byssus — were once associated with the legendary “sea silk.” For centuries, this quiet giant shaped coastal ecosystems by filtering seawater, stabilising sediments, and providing habitat for many other organisms. That long history came to an abrupt halt around 2016, when a catastrophic mass mortality event swept through the Mediterranean. Within a few years, Pinna nobilis had disappeared from most open‑sea habitats. Today, only a few remaining populations survive — mainly in coastal lagoons and deltas. In this episode, we speak with two researchers who have been closely involved in documenting and responding to this crisis: José Rafael García‑March, Institute for Environmental and Marine Science Research (IMEDMAR),Catholic University of Valencia, SpainŽeljko Pavlinec, Laboratory for Microbiology and Molecular Biology, Aquarium Pula, CroatiaTogether, they discuss how scientists first realised that something was going terribly wrong, which pathogens are involved, why the collapse unfolded so rapidly, and what makes the remaining populations so crucial for the species’ survival. The conversation also sheds light on the practical realities of conservation research: field monitoring, working with endangered species, international coordination — and the limits of intervention when extinction is already underway. LIFE PINNACARE Pinna nobilis conservation and restoration Reference: LIFE24-NAT-ES-PINNACARE/101216239 Acronym: LIFE24-NAT-ES-PINNACARE Start Date: 01/10/2025 End Date: 30/11/2029 Total Eligible Budget: 3,926,002 € EU Contribution: 2,355,601 € Official LIFE database entry: https://webgate.ec.europa.eu/life/publicWebsite/project/LIFE24-NAT-ES-PINNACARE-101216239/pinna-nobilis-conservation-and-restoration Coordinating beneficiary: Catholic University of Valencia San Vicente Mártir (Spain) Partners include: Aquarium Pula d.o.o. (Croatia),University of Zadar (Croatia),Ludwig‑Maximilians‑Universität München (Germany),Institut de Recerca i Tecnologia Agroalimentàries – IRTA (Spain),Universidad de Alicante (Spain),Universidad de Murcia (Spain),Agencia Estatal CSIC (Spain),Institut Océanographique Paul Ricard (France),University of the Aegean (Greece),Università degli Studi di Napoli Federico II (Italy). The project focuses mainly on the reservoirs and in the maintenance of individuals for indoor reproduction, since open water populations are missing. In open waters, continuing the protection and monitoring of resistant and hybrid individuals found is also important to safeguard their diversity for future crossbreeding. If no actions are taken, the few resistant individuals found so far will perish after a while without leaving any offspring, and populations in reservoirs will decay, being unable to repopulate if any natural and anthropic factors or the disease kills them.  More Links: Chasing Pinna nobilis Survivors: Current Status in Spanish Open Coastal Waters Life Pinnarca | HomeEpidemic and pathogens | Aquarium Pula ⁠Neues EU-Projekt zum Schutz seltener Mittelmeer-Muschel - LMU München Hope for the Noble Pen Shell: The Scientists in Croatia Trying to Save an Endangered Giant | Earth Journalism Network pinna_nobilis_restoration_strategy.pdf

    49 min.

Info

Worüber forscht die Wissenschaft – und was hat das mit unserem Alltag zu tun? Im Wissenschaftspodcast des Austrian Centre of Industrial Biotechnology (acib) kommen die BioteXpert*innen selbst zu Wort. Mit der neuen Staffel gehen wir tiefer rein, breiter raus – und manchmal auch thematisch quer: Wir sprechen über naturwissenschaftliche Themen mit Fokus auf Life Sciences und Biotechnologie, denken aber weiter – mit einem offenen Blick auf mögliche gesellschaftliche Auswirkungen. Wir diskutieren mit Fachleuten, spinnen Utopien – und Dystopien.