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Promoting strategies to increase healthspan, well-being, cognitive and physical performance through deeper understandings of biology.

FoundMyFitness Rhonda Patrick, Ph.D.

    • Geneeskunde
    • 4.7 • 24 beoordelingen

Promoting strategies to increase healthspan, well-being, cognitive and physical performance through deeper understandings of biology.

    Q&A with Dr. Jed Fahey on Sulforaphane, Moringa and Chemoprotection

    Q&A with Dr. Jed Fahey on Sulforaphane, Moringa and Chemoprotection

    In this special two-hour Q&A episode with Dr. Jed Fahey, a world-leading expert on the science of chemoprotection and, in particular, sulforaphane, we discuss many of the listener-submitted questions from the hundreds of live event participants.
    Get the full timeline and show notes.
    Listen to learn Dr. Fahey's thoughts on…
    00:07:19 - The minimum daily dose of sulforaphane that elicits beneficial health effects 00:12:04 - Why gauging the amount of sulforaphane in foods presents challenges 00:17:37 - Workarounds to enhance the sulforaphane in cooked foods 00:23:38 - How often to consume broccoli sprouts and how long their effects last 00:39:28 - The effects of sulforaphane on glutathione production in the brain 00:43:12 - The effects of sulforaphane on cancer 01:17:26 - Alternatives to sprouts, such as supplements (and which ones Dr. Fahey recommends) 01:33:08 - Safety concerns regarding sulforaphane In this episode, Dr. Fahey mentions the following companies, websites, and supplements:
    Brassica Protection Products Cullman Chemoprotection Center Crucera SGS® (Thorne) Oncoplex® (Xymogen) Avmacol® Vision Defense® (Swanson) MaxN-Fuze® MitoCORE® (Ortho Molecular Products) Extra resources
    Learn how to sprout at home safely by downloading the 15-page sprouting guide developed with Dr. Fahey.
    Sign-up to participate in the live every-single-month Q&A series by becoming a FoundMyFitness premium member.

    • 1 u. 56 min.
    Dr. Giselle Petzinger on Exercise for Parkinson's Disease

    Dr. Giselle Petzinger on Exercise for Parkinson's Disease

    Giselle Petzinger, MD, an associate professor of Neurology at the University of Southern California and today’s guest, studies the extensive effects of how different types of exercise, in particular skill-based exercise, can affect the clinical outcome for people with Parkinson’s disease.
    Dr. Petzinger's work focuses on understanding how to promote brain repair after injury, particularly in the context of Parkinson's disease. She is currently investigating ways to enhance neuroplasticity in a preclinical model of the disease. She has examined the role of exercise in Parkinson's disease, with emphasis on how different types of exercise affect distinct regions of the brain. Her work has implications for improving the quality of life of patients diagnosed with the neurological disorder — a condition for which there is no cure.
    In this episode, we discuss...
    00:06:57 - What is Parkinson’s disease? 00:11:57 - How symptoms of Parkinson’s disease generally only appear when ~50% of dopamine-secreting neurons in substantia nigra are lost. 1 00:14:57 - How other circuits in the brain can compensate for the loss of function of the substantia nigra. 00:18:37 - Prevalence and hereditary risk factors of Parkinson’s disease. 00:21:25 - How epidemiological studies have linked increased Parkinson’s disease risk with exposure to pesticides, herbicides, solvents, and certain heavy metals such as manganese. 1 00:26:57 - How exercise can lower the risk of developing Parkinson’s disease. 1 2 3 00:35:38 - How skill-based exercise, such as yoga, Tai chi, boxing, tango or skateboarding may play a special role in ameliorating some of the effects of the disease by driving circuit-specific effects, by creating top-down cognitive challenge for skills involved in a patient's movement through space. 00:47:49 - How serum BDNF significantly increases in Parkinson’s patients after 1 month of treadmill exercise and why this might mean better cognitive function. 1 2 00:58:33 - How treadmill exercise with heart rate 80-85% maximum for at least 3x per week slowed the progression of Parkinson’s disease symptoms. 1 01:01:31 - Why exercise may not fully replace the use of medications. 01:09:58 - How the omega-3 fatty acid DHA has some preclinical evidence suggesting it may reduce motor-symptoms and dyskinesia in Parkinson’s disease. 1 2 3 4 01:12:12 - How patients with Parkinson’s disease have higher levels of inflammatory biomarkers and how this might contribute to the disease. 1 Click here to get this episode's show notes and transcript
    Get early access with the premium members early access podcast feed, monthly Q&A sessions, an exclusive bi-weekly science digest email, and more! Click here to get started.

    • 1 u. 18 min.
    Aliquot #3: Q&A Mashup - Fasting

    Aliquot #3: Q&A Mashup - Fasting

    Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on Fasting.
    What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed.
    This collection of clips covers a range of topics related to fasting, including associated mechanisms of healthspan and longevity, purported health benefits, and when and how to break the fast.
    Episode Highlights
    00:01:36 - Fasting mimicking diet, the ketogenic diet and autoimmune diseases
    00:13:42 - Spermidine is a fasting mimetic compound
    00:16:51 - Aerobic exercises in a fasting state induces autophagy quicker than in a fed state.
    00:25:15 - Intermittent fasting, prolonged fasting and healthspan. 00:28:02 - What we know about the minimal fasting time it takes to induce autophagy and apoptosis.
    00:33:35 - Comparing and contrasting a ketogenic diet with prolonged fasting.
    00:37:33 - Rhonda compares the rejuvenation effect of time-restricted eating vs prolonged fasting vs fasting mimicking diet.
    00:41:16 - Rhonda's thoughts on coffee breaking a fast.
    00:52:29 - Supplements and other medications outside of a time-restricted eating window.
    01:01:28 - Differences between a fasting-mimicking diet vs a water-only fast. Learn more about our premium podcast feed The Aliquot by clicking here.
    Learn more about premium membership benefits by clicking here.

    • 28 min.
    Aliquot #2: Q&A Mashup - Sauna

    Aliquot #2: Q&A Mashup - Sauna

    Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on Sauna use.
    What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed.
    This collection of clips covers some of the many health benefits associated with sauna use, including heat shock protein activation, cardiovascular health, muscle mass preservation, and more.
    Episode Highlights
    00:07:00 - What are the effects of sauna and hot baths on heat shock proteins and the immune system?
    00:16:14 - What are your recommendations for infrared sauna temperature and time?
    00:24:03 - At what temperature and how long do you need to stay in the sauna to activate heat shock proteins?
    00:26:50 - Does sauna use promote excretion of heavy metals such as arsenic? 00:29:12 - Are there ways of mimicking sauna use without regular access to a sauna?
    00:33:55 - If compounds such as metformin, resveratrol and vitamin E counteract exercise-induced hormesis, would this be true for other stressors such as the sauna, fasting, broccoli sprouts, polyphenols?
    00:37:06 - How does fasting affect human growth hormone and IGF-1 in respect to muscle mass?
    00:43:30 - Can saunas be used during fasting to preserve more muscle and increase fat burning?
    00:45:50 - Can saunas be used to treat headaches? Learn more about our premium podcast feed The Aliquot by clicking here.
    Learn more about premium membership benefits by clicking here.

    • 18 min.
    Aliquot #1: Q&A Mashup - Pregnancy and child development

    Aliquot #1: Q&A Mashup - Pregnancy and child development

    Get a sample of our new premium member's content, known as Aliquots, by listening to this in-depth Q&A mashup on pregnancy and child development.
    What's an aliquot, you may ask? Aliquots are special, curated segments prepared and distributed to premium members via the premium members podcast feed.
    This particular collection of segments covers every single major discussion of pregnancy and child development spanning years of members-only Q&As.

    Just for a few examples, it covers...
    My pre-pregnancy regimen, including diet, exercise, vitamins and sleep Nutrition for babies and toddlers to maximize brain development and growth Extra precautions that I took during my pregnancy And much, much more! Learn more about our premium podcast feed The Aliquot by clicking here.
    Learn more about premium membership benefits by clicking here.

    • 24 min.
    The Biology of Breast Milk

    The Biology of Breast Milk

    This episode aims to be the most comprehensive compendium on the biology of breast milk ever recorded. Looking at the converging clinical and animal evidence of the impact of breast milk paints a complex and beautiful mosaic of developmentally supportive effects that range from allowing the mother to act as a “compensatory” immune system to possibly supporting the development of entire organ systems through the integration of maternal stem cells found in breast milk.
    Episode Highlights
    00:07:11 - Breast milk composition and production 00:09:59 - Human milk oligosaccharides in breast milk establish the infant gut microbiome 00:15:48 - Omega-3 fatty acids and other components in breast milk boost brain development 00:18:14 - Vitamins and minerals in breast milk 00:22:05 - Breast milk stem cells and multi-organ microchimerism 00:22:54 - Harmful substances transferred to infant via breast milk 00:28:03 - The effects of breastfeeding on the infant's immune system 00:31:17 - Effects on intelligence 00:34:36 - Breastfeeding as a benefit to maternal health Get our detailed summary, timeline, references and more on the FoundMyFitness episode page.
    Breastmilk and breast feeding is now a dedicated Topic section on the website. View that article by clicking here.
    Did you enjoy this episode? If you’re interested in learning more about this topic, check out a preview of our very first Aliquot episode: Aliquot #001: Pregnancy & Child Development. It features a compilation of pregnancy and child development-related topics taken from several Q&A episodes over the last couple of years.
    Click here to hear this preview of our premium podcast The Aliquot by clicking here now.

    • 38 min.

Klantrecensies

4.7 van 5
24 beoordelingen

24 beoordelingen

Gompie ,

Superleerzaam en rechtstreeks uit de wetenschap

Dr. Patrick laat allerlei belangrijke onderwerpen over gezondheid en leefstijl aan bod komen. Sprekend in hoog tempo én met een hoge informatiedichtheid, levert ze zo relevante en goed onderbouwde informatie waar ik echt iets mee kan. Haar gasten komen net als zij rechtstreeks uit de wetenschap en zijn vaak voorlopers in hun veld.
Stiekem ben ik best een beetje jaloers op het brein van Rhonda Patrick. Wow! Aanrader voor wie écht wil weten waar we nu staan.

jorisengel ,

Great podcast

Great podcast, really learning things I would not have much acces too and explained very well. For a non science degree person. Keep it up!!

Perenboom23 ,

Dense biology podcast, full of great advice

Almost each and every episode I have to scroll back certain parts in the podcast because I didn’t get something. This podcast is not for the faint hearthed or people just want to hear a casual conversion about health. It is very deep and thorough, the podcast guests are almost always the best in their respective fields.

Dr. Rhonda Patrick does a great job of selecting the right guests and next to that she always tries to learn something out of it herself and is always open to almost anything.

If you want to get in deep into the biology of the human being and learn something in the process this podcast is for you. I really want to thank you for the great insights I got from this podcast so far.

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