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第2789期:The Life-saving Secrets In Your Baby(5)

I also think there's a systematic or institutional resistance, right? Because genomics is thetipof the spear for preventive care. It's really the first in a series of things that we need to bring in order to preserve our health: multiomics, proteomics, transcriptomics, wearables, all the exciting things we've heard about that will keep us well instead of simply treating us when we're sick.我也认为存在一种系统性或制度性的抵制,对吧?因为基因组学是预防医疗的“矛头”。它实际上是我们为了保持健康所需要引入的一系列手段中的第一步:多组学、蛋白质组学、转录组学、可穿戴设备,所有这些令人兴奋的技术,都是为了帮助我们保持健康,而不仅仅是在生病时才进行治疗。


Now, I'm happy to tell you that I've co-founded an international consortium on newborn sequencing. It's grown to 27 groups around the world that are all doing this in different healthcare systems. We get together, we compare notes, we share data. It's really exciting. I go to these annual meetings, it’s the most exciting meeting I go to every year, we feel like we're inventing an entirely new field of medicine.现在,我很高兴地告诉大家,我共同创立了一个关于新生儿基因测序的国际联盟。它已经发展到全球27个团队,他们在不同的医疗体系中开展类似的工作。我们聚在一起,交流经验,分享数据,这令人无比兴奋。我每年都会参加这个年度会议,这也是我每年最激动人心的一次会议,因为我们感觉自己正在开创一个全新的医学领域。


But if we really want to invent the future, we've got to do something different. If we really want to invent the future, we've got to realize that a child's DNA doesn't change over time, but the science is changing all the time. And so what that means is we should sequence your child's DNA, and we should revisit and reanalyze that DNA over and over again to truly create the dream of genome-informed medicine. Because each and every year there will be new insights and new treatments available.但如果我们真的想要创造未来,就必须做一些不同的事情。我们必须认识到:孩子的DNA不会随时间改变,但科学却在不断进步。这意味着我们应该对孩子的DNA进行测序,并且反复重新分析它,从而真正实现“基因组指导医疗”的梦想。因为每一年都会出现新的发现和新的治疗方法。


This isn't offered anywhere in the world, but I'm happy to tell you that we are trying to build this. We are building an AI-enhanced digital health platform so that you, your grandchildren, your children, your pediatricians, your health care centers, your employers, your nations can do this at scale.目前,全世界还没有地方提供这种服务,但我很高兴地告诉大家,我们正在努力构建它。我们正在打造一个由人工智能增强的数字健康平台,这样你、你的孩子、你的孙辈、儿科医生、医疗中心、雇主乃至国家,都可以大规模开展这一工作。


It's going to take a certain amount of courage to change the way we think about disease, to embrace the knowledge of risk in order to preserve our health, rather than waiting for us and our children to get sick and treating them there. But if we can do this, if we can embrace this, we can save millions of lives and usher in an entirely new era of genome-inspired medicine.要改变我们对疾病的看法,需要一定的勇气。我们必须接纳风险知识,以此来保护我们的健康,而不是等到我们和孩子生病后再去治疗。但如果我们能够做到这一点,如果我们能够拥抱这一理念,我们就能拯救数百万人的生命,并迎来一个由基因组启发的全新时代的医学。