AudioScholar Pathology Weekly

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Pathology — a weekly podcast briefing of the most significant peer-reviewed pathology literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

  1. 6 days ago

    This Week in Pathology — Sep 12, 2026

    Welcome to This Week in Pathology. This week we're covering 10 notable papers spanning classification and molecular taxonomy, new immunohistochemical markers that solve everyday diagnostic problems, and the recurring challenge of cutaneous and soft t… This week's papers: 1. Gastric carcinoma classification in the WHO 6th edition (2026): Updated framework and emerging entities. — Virchows Archiv 2026 2. Methylation profiling in CNS tumor diagnostics: a single-centre real-world experience from Central Europe. — Virchows Archiv 2026 3. An Agreement Study of Stromal Cellularity, Stromal Cell Atypia, and Tumor Border of Phyllodes Tumors of the Breast. — Modern Pathology 2026 4. Sarcomatoid malignancies with strong PD-L1 expression often represent dedifferentiated or undifferentiated melanomas. — Human Pathology 2026 5. FOG1: A Highly Sensitive and Specific Diagnostic Marker for Gastroesophageal Adenocarcinoma. — The American Journal of Surgical Pathology 2026 6. Cribriform tumors of the skin: CD38 expression distinguishes from histologic mimics in a multi-institutional series. — Virchows Archiv 2026 7. C-Cell Lesions and Medullary Thyroid Carcinoma: A Review. — Modern Pathology 2026 8. Uterine Sarcomas With KDM2B Fusion: Clinicopathological Analysis of Three Cases Supporting a Novel BCOR-Altered Entity. — The American Journal of Surgical Pathology 2026 9. Primary Cutaneous Apocrine Carcinoma: Clinicopathologic, Immunohistochemical, and Molecular Characterization of Twenty-Seven Cases. — Modern Pathology 2026 10. Histopathologic, Genomic, and Clinical Characteristics of Primary Cutaneous Melanocytic Tumors With Concomitant NRAS Q61 and IDH1 R132C Mutations. — Modern Pathology 2026 Listen at https://audioscholar.cc/episode/ubw7m4shx8

  2. 5 Sept

    This Week in Pathology — Sep 5, 2026

    Welcome to This Week in Pathology. This week we're covering 10 notable papers spanning three broad themes: artificial intelligence and quantification in the laboratory, consensus and standardization efforts that shape how we report, and the molecular… This week's papers: 1. International Society of Urological Pathology Multidisciplinary Expert Consultation Conference on Evaluation of Treatment Effects in Prostate and Bladder Cance… — The American Journal of Surgical Pathology 2026 2. Guidance for laboratory implementation, governance and continuous assurance of artificial intelligence in histopathology. — Virchows Archiv 2026 3. Inflammatory bowel disease-associated colorectal dysplasia: the expanding morphologic landscape and diagnostic challenges. — Virchows Archiv 2026 4. Preanalytical variables in surgical pathology: practical sources of diagnostic error before microscopic interpretation. — American Journal of Clinical Pathology 2026 5. Visual steatosis assessment: method-dependent variation and systematically higher estimates compared with AI measurement. — Histopathology 2026 6. Punctate nuclear low-risk HPV chromogenic in situ hybridization in digital papillary adenocarcinoma: a practical tool for identifying HPV42 in routine patholog… — Histopathology 2026 7. Folate Receptor Alpha Expression Across the Spectrum of Serous Tubal Lesions: An Adjunct Biomarker for Distinguishing Serous Tubal Intraepithelial Carcinoma Fr… — The American Journal of Surgical Pathology 2026 8. Deep learning in breast cancer histopathology: predicting and detecting axillary lymph node metastasis. — Virchows Archiv 2026 9. Expanding the Morphologic, Clinical, and Molecular Spectrum of Succinate Dehydrogenase A (SDHA)-Deficient Renal Cell Carcinoma: A Case Series With Review of Li… — The American Journal of Surgical Pathology 2026 10. Aggressive high-grade papillary-patterned renal cell carcinomas harboring FLCN mutations: expanding the clinicopathological spectrum in Birt-Hogg-Dubé syndrome… — Virchows Archiv 2026 Listen at https://audioscholar.cc/episode/28mnr2n7xw

  3. 30 Aug

    This Week in Pathology — Aug 30, 2026

    Welcome to This Week in Pathology. This week we're covering 10 notable papers spanning molecular biomarker interpretation and its reproducibility, classification updates in soft tissue, skin and gastrointestinal pathology, and the recurring theme of… This week's papers: 1. Liquid biopsy in solid tumours: expert opinion paper of the European society of pathology — Virchows Archiv 2026 2. Cutaneous lymphomas - an update — Histopathology 2026 3. Morphologic correlates of genetic subtypes of acute myeloid leukemia — Human Pathology 2026 4. Diagnostic reproducibility, spatial heterogeneity, and survival outcomes of HER2-Null, HER2-Ultralow, and HER2-Low categories in invasive breast carcinoma — Virchows Archiv 2026 5. Tumours of the duodenum and the ampulla of Vater: An overview of the key criteria for their classification, pathogenesis, and molecular assessment — Virchows Archiv 2026 6. Toward Improved Classification of Vulvar Smooth Muscle Tumors: A Clinicopathologic Study of 35 Cases — The American Journal of Surgical Pathology 2026 7. Diversion-Associated Rectal Pathology in Patients With and Without Inflammatory Bowel Disease: A Rectum-Exclusive, Blinded Histologic Comparison and Practical… — The American Journal of Surgical Pathology 2026 8. HER2 Intratumoral Heterogeneity in Salivary Duct Carcinoma: Association With Treatment Response and Comparison Between Primary and Metastatic Lesions — Modern Pathology 2026 9. Bile Duct-Narrowing Neuroendocrine Tumors Show a PDX1+/CDX2+ Phenotype Resembling Duodenal Rather Than Pancreatic Neuroendocrine Tumors — Modern Pathology 2026 10. Comparison of Albumin In-Situ Hybridization in Genetically Characterized Cholangiocarcinoma and Tumors of Other Origins — Modern Pathology 2026 Listen at https://audioscholar.cc/episode/agcsv7gpqb

  4. 23 Aug

    This Week in Pathology — Aug 23, 2026

    Welcome to This Week in Pathology. This week we're covering ten notable papers spanning predictive biomarker testing in gastrointestinal and gynaecological cancers, the diagnostic pitfalls of immunohistochemistry when a single stain is asked to do to… This week's papers: 1. Pancreatic ductal adenocarcinoma and its subtypes: clinical relevance of histopathology and molecular characterization, integrating the key updates of the 2026… — Virchows Archiv 2026 2. Comprehensive Profiling of Claudin 18.2 Immunohistochemical Expression in 564 Surgically Resected Gastric and Gastroesophageal Junction Adenocarcinomas — Modern Pathology 2026 3. Pathologist-Recommended Molecular Testing in Endometrial Cancer: A Single-Institution Experience — Human Pathology 2026 4. Thyroid nodules of uncertain malignant potential non-conforming to World Health Organization diagnostic criteria - clinicopathologic and molecular characteriza… — Human Pathology 2026 5. Nondiffuse p16 Expression in HPV-Associated and HPV-Independent Cervical Squamous Cell Carcinomas — The American Journal of Surgical Pathology 2026 6. Inflammatory and Nested Testicular Sex Cord Tumor: Clinicopathologic and Molecular Features — Modern Pathology 2026 7. SMARCA4-deficient undifferentiated malignancies in the digestive system: clinicopathological features and prognostic significance with genomic insights from th… — The Journal of Pathology 2026 8. SRF fusion genes in myoid soft tissue tumors — The Journal of Pathology 2026 9. Assessment of isochromosome 12p supports that pagetoid involvement of the rete testis represents spread of germ cell neoplasia in-situ — Human Pathology 2026 10. Pattern-based interpretation of SOX2 expression in ovarian teratomas: avoiding diagnostic pitfalls in the distinction between immature and mature neuroectoderm… — Histopathology 2026 Listen at https://audioscholar.cc/episode/2thxxsntgs

  5. 16 Aug

    This Week in Pathology — Aug 16, 2026

    Welcome to This Week in Pathology. This week we're covering 10 notable papers spanning smarter test-triage strategies that replace expensive downstream assays, the persistent problem of interobserver variability and what artificial intelligence is ac… This week's papers: 1. Real-World Experience With TRBC1 Immunohistochemistry Across Cutaneous T-Cell Lymphoma Subtypes: A Large Cohort Study — Modern Pathology 2026 2. Duct Quest: An International Survey of Genitourinary and Community Pathologists Reveals Diagnostic Uncertainties in Separating Atypical Intraductal Proliferati… — Human Pathology 2026 3. Additional sectioning and AI-assisted diagnosis reveal underdiagnosis of serous (pre)malignancies in fallopian tube specimen from BRCA1/2 carriers — Histopathology 2026 4. HER2 status in extrahepatic cholangiocarcinoma and gallbladder carcinoma: concordance between immunohistochemistry and chromogenic in situ hybridization in 140… — Human Pathology 2026 5. Leveraging large language models to enhance cytopathology: Opportunities, challenges, and future directions; a practical review from the ASC Clinical Practice… — Cancer Cytopathology 2026 6. Experience of the United States-Canadian Mesothelioma Reference Panel 1985-2026: Historical Review and New Developments in Mesothelial Pathology — Archives of Pathology & Laboratory Medicine 2026 7. Panel of Methylation-based PCRs for Separating Mucinous Lung Adenocarcinomas from Gastrointestinal Metastases Involving the Lung — Modern Pathology 2026 8. Intratumoral IDH1 mutation status in intrahepatic cholangiocarcinoma is homogeneous — Histopathology 2026 9. Comprehensive and reproducible grading of the Updated Sydney System in gastric biopsies using artificial intelligence: multi-pathologist validation and a reade… — Histopathology 2026 10. Streamlining Urinary Tract Infection Evaluation in a Large Pediatric Hospital System: Feasibility of Reflex Urine Culture After Urinalysis With Microscopy — Archives of Pathology & Laboratory Medicine 2026 Listen at https://audioscholar.cc/episode/quzfrq6zh3

  6. 9 Aug

    This Week in Pathology — Aug 9, 2026

    Welcome to This Week in Pathology. This week we're covering 10 notable papers spanning diagnostic criteria and classification challenges, the expanding role of genomic and molecular profiling in tissue and cytology specimens, and the limits of artifi… This week's papers: 1. Evidence for non-mucinous pulmonary lesions with adenocarcinoma in situ morphology exceeding the current 3 cm WHO threshold. — Virchows Archiv 2026 2. An Integrative Morphological and Genomic Analysis With a Refined FISH Threshold and Novel Kinase Fusions in a Large Asian Cohort of Spitzoid Neoplasms. — Modern Pathology 2026 3. Diagnostic performance of artificial intelligence models trained on scattered single-cell images is not preserved for hyperchromatic crowded cell groups in cer… — Cancer Cytopathology 2026 4. When genomics and histopathology diverge: insights from pathologic review of genomic-directed specimens. — Virchows Archiv 2026 5. Feasibility of routine clinical liquid-based cytology for lung cancer compact panel testing. — Cancer Cytopathology 2026 6. Optical genome mapping enhanced by refined variant interpretation in pediatric acute lymphoblastic leukemia. — The Journal of Pathology 2026 7. The histopathological differential diagnosis of BPDCN and other plasmacytoid dendritic cell proliferations. — Virchows Archiv 2026 8. Single-cohort next-generation sequencing analysis of 713 anaplastic thyroid carcinomas: unreported gene alterations and actionable targets. — American Journal of Clinical Pathology 2026 9. SMARCA4-altered malignancies: Cytologic diagnostic challenges and clinicopathologic correlation. — Human Pathology 2026 10. Targeted Transcriptomic Profiling Identifies Biomarkers and Molecular Features Associated With Immunotherapy Response in Classic Hodgkin Lymphoma. — Modern Pathology 2026 Listen at https://audioscholar.cc/episode/njkg5up3td

  7. 2 Aug

    This Week in Pathology — Aug 2, 2026

    Welcome to This Week in Pathology. This week we're covering 10 notable papers spanning diagnostic mimics that can send a case down the wrong treatment pathway, molecular refinement of familiar tumour families in thyroid, bone and soft tissue, and the… This week's papers: 1. Sporadic Burkitt Lymphoma Lacking MYC Protein Expression: A Rare Entity With Diagnostic Pitfalls and Dismal Prognosis — The American Journal of Surgical Pathology 2026 2. Poorly differentiated lung adenocarcinomas with concurrent ALK and CD30 expression: a diagnostic pitfall mimicking ALK-positive anaplastic large-cell lymphoma — Histopathology 2026 3. DEK::AFF2 Fusion Sinonasal Tract and Skull Base Nonkeratinizing Squamous Cell Carcinoma: An Expanded Single-Center Series of 50 Cases — The American Journal of Surgical Pathology 2026 4. Multifocal Thyroid Follicular Cell-Derived Carcinomas With Discordant Molecular Drivers: Morphologic and Clinical Features in 63 Patients — The American Journal of Surgical Pathology 2026 5. Practical considerations for pathologists when selecting digital pathology systems: an ESDIP guide — The Journal of Pathology 2026 6. Molecular Subtypes and Genetic Diagnostics in B-cell Acute Lymphoblastic Leukemia — Human Pathology 2026 7. Follicular-Patterned Lesions of the Thyroid Gland — Modern Pathology 2026 8. Metastatic High-Grade Endometrioid Carcinoma to the Lung With Pilomatrix Carcinoma-Like Morphology: Potential for Misdiagnosis as Non-Small Cell Carcinoma — The American Journal of Surgical Pathology 2026 9. Chondromyxoid fibroma with limited or no chondromyxoid stroma: A clinicopathological study of 3 cases — Virchows Archiv 2026 10. GJA4-Associated Cavernous Venous Malformation: A Distinct Morphologic and Molecular Subtype of Venous Malformation — Modern Pathology 2026 Listen at https://audioscholar.cc/episode/cma99gkthj

  8. 26 Jul

    This Week in Pathology — Jul 26, 2026

    Welcome to This Week in Pathology. This week we're covering 8 notable papers spanning genitourinary oncology diagnostics, molecular pathology of gastrointestinal and breast cancers, and artificial intelligence applications in anatomic pathology. Let'… This week's papers: 1. Enfortumab Vedotin and Pembrolizumab in Cisplatin-Eligible Bladder Cancer. — The New England journal of medicine 2026 2. Limited Availability of Short Tandem Repeat Genotype Testing in the United States for Diagnosis of Partial Hydatidiform Mole: A Dilemma for Practicing Precisio… — The American journal of surgical pathology 2026 3. Next-Generation Sequencing of Multivergent Morphologies in Colorectal Carcinomas Identifies Unique Targetable Alterations. — The American journal of surgical pathology 2026 4. FGFR2 amplification and fusion identified by NGS align with FGFR2b overexpression. — Virchows Archiv : an international journal of pathology 2026 5. AI-assisted TURP slide review: a multi-reader study of efficiency, diagnostic performance, and human-AI error patterns. — Virchows Archiv : an international journal of pathology 2026 6. From Information Extraction to Clinical Reasoning: A Systematic Scoping Review of Large Language Models in Cancer Pathology Reports. — Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2026 7. Keratin 17 immunocytochemistry in urine cytology for urothelial carcinoma detection: Diagnostic performance and interobserver agreement in a prospective real-w… — Cancer cytopathology 2026 8. Deep learning-based assessment of HER2-ultralow expression in breast cancer: a multi-center validation study across primary and metastatic lesions. — Virchows Archiv : an international journal of pathology 2026 Listen at https://audioscholar.cc/episode/yjyf4npccs

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Pathology — a weekly podcast briefing of the most significant peer-reviewed pathology literature, synthesized from PubMed and delivered as ~10-minute audio. For practicing physicians. Generated by AudioScholar at audioscholar.cc.

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