The TED Interview TED Talks

Biochemist Jennifer Doudna won the 2020 Nobel Prize in Chemistry for pioneering CRISPR, a revolutionary biotech tool that can edit DNA with unprecedented precision and ease. But how exactly does CRISPR work, and what consequences may arise from altering our internal makeup? She talks to Chris about the remarkable effects CRISPR can have on our lives--from eradicating genetic diseases to slowing the climate crisis--as well as the ethical and moral questions we must grapple with when it comes to changing who we are.

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From governments to airlines to your favorite eco-friendly clothing brand, tree-planting campaigns are everywhere. Reforesting the planet has become one of the quickest, easiest and most ubiquitous ways to reduce our carbon footprint...but is it actually helping to stop climate change? Ecologist Thomas Crowther speaks with Chris about how planting trees can actually hurt the environment -- unless it's done right. In which case, it can be a pivotal solution in our efforts to end the climate crisis.

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We all have to give a presentation at some point in our lives—on a stage, in a conference room, and, these days, on Zoom. So what makes a good speech? In this episode from How To! science writer David Epstein turns the microphone on Chris to find the answer. Chris breaks down some of the most famous talks of all time and solves an unusual challenge from a 6th-grader named Lucy: can he help her prepare for the biggest speech of her young life?

This is an episode of How To!, a podcast from Slate. For more episodes, find it wherever you're listening to this.

Some believe our world has changed at a rapid pace in recent decades. From the rise of the internet to the proliferation of startups spinning out inventions, it can certainly seem that way. In this episode, though, economist Tyler Cowen argues that none of this has really transformed the ways we live over the last 50 years. But he contends that now that's changing, as new breakthroughs in science and medicine push us out of the so-called "Great Stagnation" into a new era of meaningful innovation.

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What does it take to persevere and succeed, not just in our careers but in all aspects of our lives? For psychologist Angela Duckworth, the answer can be summed up in one concept: grit. She explains the ingredients in grit and the experiences that make one person persist where another gives up — and offers concrete steps to instill grit early in life and sustain it.

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From the strikes that transformed the world's view on climate change to the marches that demanded equity and justice for Black lives, there has been a new awakening of people passionate about creating change. As founder and CEO of Acumen, Jacqueline Novogratz decided early on to dedicate her life's work to doing just that. In this episode, Chris talks to Jacqueline (who he also happens to be married to) about the wisdom she gained from abandoning a lucrative career as a banker to start a nonprofit dedicated to eradicating global poverty, and the moral imagination -- and difficult tradeoffs -- she believes are necessary to make a transformative impact on the world.

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