Peptides Explained

John Garrett

Peptides Explained breaks down the most talked-about peptides and GLP-1 medications in health, fitness, and longevity — including semaglutide, tirzepatide, BPC-157, TB-500, and more. Hosted by Registered Nurse John Garrett, this podcast explains how these compounds work, why they're popular, what the research shows, and the real risks and side effects — all in plain language. No bro science. No hype. Just clear, foundational education. For informational purposes only. Not medical advice. For Research Peptides; Offlinepeptides.com/ref/johngarrett/ https://www.skool.com/peptides-explained-15

  1. 19 hr ago

    What the Heck Is Visceral Fat? (And Why People Keep Getting It Wrong)

    Everyone keeps calling belly fat "visceral fat." That is not how anatomy works. In this crossover episode, John breaks down the difference between visceral and subcutaneous fat, why visceral adipose tissue matters metabolically, how it is actually measured, what waist circumference can and cannot tell you, and what the evidence says about GLP-1 therapies and tesamorelin.

  2. 19 hr ago ·  Bonus

    Exclusive Player Interviews, Insider Access & Unfiltered Keyshawn Johnson: The Schultz Report

    Introducing Adrian Peterson's Top 5 RBs Right Now And All Time + Keyshawn Johnson Reacts To The Biggest NFL News from The Schultz Report. Follow the show: The Schultz Report Adrian Peterson joins Jordan Schultz for a wide-ranging conversation: why he chose Oklahoma over Texas and USC, how his father shaped him, who he considers the best running backs right now and of all time, and the Ray Lewis goal-line hit he never forgot. Plus Jordan and Keyshawn Johnson react to Lane Johnson's retirement and the Cam Jurgens trade, discuss the pressure on Nick Sirianni and the Eagles, break down the NFL's officiating controversies, and ask whether USC should move on from Lincoln Riley if the Trojans miss the playoff. Friday Flowers go to Chiefs rookie cornerback Mansoor Delane. Watch the full episode on our Youtube Channel! Timestamps: 00:00 - Eagles Lose Lane Johnson & Cam Jurgens 05:49 - NFL Referees, Fines & Keyshawn's Uniform Police Story 12:32 - Should USC Move On From Lincoln Riley? 21:23 - Adrian Peterson: Choosing Oklahoma & Growing Up With His Dad 29:41 - Adrian Peterson On Jahmyr Gibbs & Bijan Robinson 33:13 - Vikings What-Ifs, Competitiveness & Randy Moss 45:14 - Adrian Peterson's Top 5 Running Backs & All Time 50:29 -  Ray Lewis, Patrick Willis & Pete Carroll 56:12 - Adversity, ACL Comeback & The Road Rage Interview 1:03:29 - Sunday Night Parlay & Friday Flowers: Mansoor Delane 🔔 Subscribe to The Schultz Report for more inside access, player interviews, and NFL storylines all season long. 👉 Follow us on social to keep up with the show X: https://x.com/theschultzrprt IG: https://www.instagram.com/theschultzreport Tik Tok: tiktok.com/theschultzreport Download the Fanatics Sports & Casino App now, the new all-in-one app for sports fans, bringing together ways to bet, trade, or play in one experience. In association with Rain Delay Media. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising. DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to team@podroll.fm.

    Exclusive Player Interviews, Insider Access & Unfiltered Keyshawn Johnson: The Schultz Report

  3. 5 days ago

    Vesugen and Vascular Aging: Interesting Biology or Overhyped Claim?

    Vesugen is only three amino acids long: lysine, glutamate, and aspartate — KED. Yet it is promoted as a vascular bioregulator that may support endothelial health and even "rejuvenate" aging blood vessels. In this episode, John Garrett looks at what the endothelial research actually measured, the proposed gene-regulation mechanism, a small human blood-flow report, and the large gap between an interesting cell signal and a proven cardiovascular therapy. No hype. No dismissal. Just the biology, the evidence, and what remains unknown. INSTAGRAM CAPTION Three amino acids. K. E. D. And somehow that became a claim about "rejuvenating" aging blood vessels. Vesugen is one of the more interesting Khavinson bioregulator peptides because there is actual published endothelial-cell research behind the concept. But there is a big difference between: changing a cell marker improving endothelial function and preventing cardiovascular disease. In the new episode of Peptides Explained, I break down the mechanism, the human signal, the evidence gaps, and the question that matters most: Can Vesugen actually make aging blood vessels younger — or is the marketing way ahead of the science? Educational only. Not medical advice. #PeptidesExplained #Vesugen #KEDPeptide #Peptides #Longevity #VascularHealth #EndothelialHealth #CardiovascularHealth #HealthyAging #Biohacking #PeptideScience #MedicalScience

  4. 5 Oct

    FLGR-242 Explained: Smarter Follistatin—or Unproven Hype?

    FLGR-242 is being called a smarter, longer-acting follistatin. John examines the advertised construct, the activin-sparing and 19-day half-life claims, the difference between pathway evidence and product evidence, and why transformation photos cannot establish pharmacology or safety.

  5. 30 Sept

    Follistatin Explained: Can You Really Remove the Muscle-Growth Brake?

    Follistatin can bind myostatin—one of the body's major restraints on skeletal-muscle growth. Animal studies are dramatic, and small human gene-therapy studies have produced encouraging signals in serious muscle disease. But is a vial labeled "Follistatin-344" equivalent to the therapy used in those trials? John Garrett explains FST288, FST315, and FST344; the myostatin/activin pathway; the difference between gene therapy and recombinant protein; the evidence for muscle size versus function; and the key safety and product-identity questions. Follistatin is not an FDA-approved muscle-building medication. Educational content only; not medical advice. Explore the free Peptides Explained app: https://app.peptidesexplained.info

  6. 28 Sept

    Glutathione: The "Master Antioxidant" — or Master Marketing?

    Glutathione gets called the "master antioxidant," and the underlying biology really is important. But does that mean oral supplements, liposomal products or glutathione IVs deliver the sweeping detox, energy, immune and anti-aging benefits often attached to them? John breaks down glutathione biology, the GSH/GSSG cycle, oral human data, NAC, skin-related research and the gap between changing a biomarker and changing a meaningful health outcome. The episode also covers the 2026 FDA warning and recalls involving compounded injectable glutathione and elevated endotoxin levels. The key question: where does established biology end and wellness marketing begin? Educational only. Not medical advice.

  7. 23 Sept

    GLP-1 Split Dosing: This Is NOT Microdosing

    For more information on Research Peptides go to PeptidesExplained.info/OfflinePeptides Is taking smaller GLP-1 doses multiple times per week actually "microdosing"? Not necessarily. This episode separates split dosing from true dose reduction and explains the pharmacokinetic logic using semaglutide, tirzepatide, and retatrutide. John breaks down half-life, peaks, troughs, total exposure, and why changing the schedule does not automatically mean using less drug. We also examine the major evidence gap: once-weekly dosing has a strong clinical foundation for semaglutide and tirzepatide, while retatrutide remains investigational — and direct randomized evidence showing routine split dosing is superior is not established. Educational only. No individualized dosing protocols are provided.

  8. 21 Sept

    Icotyde: The Oral Peptide That Could Change Medicine

    Download The Peptide App at ThePeptide.App/Explained For more information on research peptides check out PeptidesExplained.info/OfflinePeptides A peptide…in a pill? Icotyde, or icotrokinra, is an FDA-approved oral peptide designed to block the IL-23 receptor in moderate-to-severe plaque psoriasis. In Phase 3 trials, it produced substantial skin clearance and outperformed an established oral comparator on several key endpoints. But the biggest story may be the delivery platform itself. Peptides usually struggle to survive the digestive tract and reach circulation. Icotyde shows what can happen when medicinal chemistry, structural engineering and extreme receptor potency come together. This episode breaks down what worked, what the safety data show, and what this does—and does not—mean for the future of oral peptides. Educational only. Not medical advice.

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About

Peptides Explained breaks down the most talked-about peptides and GLP-1 medications in health, fitness, and longevity — including semaglutide, tirzepatide, BPC-157, TB-500, and more. Hosted by Registered Nurse John Garrett, this podcast explains how these compounds work, why they're popular, what the research shows, and the real risks and side effects — all in plain language. No bro science. No hype. Just clear, foundational education. For informational purposes only. Not medical advice. For Research Peptides; Offlinepeptides.com/ref/johngarrett/ https://www.skool.com/peptides-explained-15

Information

  • Creator
    John Garrett
  • Years Active
    2026
  • Episodes
    59
  • Rating
    Clean
  • Copyright
    © 2026
  • Show Website
    Peptides Explained

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