Trying with Dr. Sasha Hakman

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As a double board-certified OB-GYN and Reproductive Endocrinology and Infertility specialist, I've dedicated my career to helping women understand and navigate their reproductive health, but my passion for this podcast goes beyond my clinical background. My own personal experience with infertility gives me a firsthand understanding of the emotional and physical weight of this journey, and it's what drives me to show up for this community every week. Trying with Dr. Sasha Hakman has grown because the conversation needed to grow too. Yes, we still cover the trying-to-conceive journey: the IUIs, the IVFs, the unexplained infertility, the grief, and the hope. But we also go deeper: hormones, PCOS, endometriosis, thyroid health, perimenopause, egg freezing, cycle tracking, and everything in between. Every episode, I break down complex science in plain language with no jargon, no shame, no sugarcoating, through expert interviews, real patient stories, and the latest innovations in women's health. Because the more you understand your body, the more power you have.

  1. 2 days ago

    Dr. Mamina Turegano on Hormonal Acne, Hair Loss & Skincare That Works

    We share more with a reproductive endocrinologist than you'd think — hormones drive skin and hair just as much as fertility. In this episode, Dr. Sasha sits down with triple board-certified dermatologist Dr. Mamina Turegano to break down what's really behind hormonal acne and hair loss, the environmental factors quietly wrecking our skin, and the exact prescriptions, supplements, and skincare routines that actually work. In this episode, we cover: Why acne is so common (80-90%+ of women experience it) and why it's rising in adulthood The environmental theories behind the "acne epidemic" — diet, sugar, dairy, fiber intake, caffeine, microplastics, and endocrine disruptors Why chronic stress, poor sleep, and constant phone/screen stimulation are affecting our hormones and skin How to tell if your acne is truly "hormonal" — jawline breakouts, cystic bumps, and the testosterone-to-estrogen ratio (not the absolute number) that drives flares PMOS (formerly PCOS) and how androgen imbalances show up as cystic acne, hirsutism, and hair loss Dr. Turegano's diagnostic workup: history, hormone testing, functional medicine referrals, Dutch tests, and gut microbiome testing The acne treatment ladder — topical retinoids, spironolactone, isotretinoin (Accutane), and where supplements like omega-3s, zinc, pumpkin seed oil, vitex, and DIM fit in Why the type of progestin in your birth control can make acne better or worse — and the role of drospirenone (Yasmin) Coming off birth control or spironolactone without your skin spiraling Normal vs. abnormal hair shedding, telogen effluvium vs. androgenic alopecia, and why postpartum hair loss hits so hard The most common hidden cause of hair loss: iron deficiency (even without anemia) — plus the trick to actually absorbing your iron supplement Dr. Turegano's hair loss lab panel: thyroid (TSH, free T3/T4, antibodies), vitamin D, zinc, ANA, ferritin, and androgens Hair growth treatments ranked: topical and oral minoxidil, finasteride/dutasteride, spironolactone, and the supplements worth trying (Nutrafol, Viviscal Pro, biotin myths) The truth about biotin — why it can mask a real heart attack on lab testing Building a skincare routine: cleanser, moisturizer, sunscreen as the non-negotiable foundation, plus where retinoids and vitamin C serums fit in Dr. Turegano's personal AM/PM skincare routine and product picks Follow Dr. Mamina Turegano! Instagram/social: @dr.mamino Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more! Thank you to our sponsors!  For a limited time, try OneSkin with 15% off using code DRSASHA at oneskin.co/DRSASHA Thousands of people are already using Rula to get affordable, high-quality therapy that’s actually covered by insurance. Visit Rula.com/DRSASHA to get started Use my link at thrivemarket.com/trying to get $20 off your first three orders —  That covers your membership fee! Sign up now before this exclusive offer ends. Head to vitaclean.co and use code DRSASHA at checkout for 20% off your Starter Kits purchase. Learn more about your ad choices. Visit megaphone.fm/adchoices

  2. 5 Aug

    Secondary Infertility Causes, Diagnosis & Treatment: Everything You Need to Know

    Secondary infertility affects millions of women — and yet it remains one of the most isolating diagnoses in the fertility space. You already have a child, so you feel like you can't complain. But the confusion, grief, and frustration are completely real. In this solo episode, Dr. Sasha Hakman breaks down exactly what secondary infertility is, why it happens, and what to do about it — including causes that will genuinely surprise you. If you've been pregnant before and are struggling to get pregnant again, this episode was made for you. In this episode, we cover: What secondary infertility actually is by definition — and why pregnancy loss counts too, even if you never brought a baby home Ovulatory dysfunction: why it's the #1 cause of secondary infertility, how PCOS, thyroid disease, and high prolactin play a role, and how postpartum weight changes can quietly shut down ovulation How to track your cycle and confirm ovulation at home — including Dr. Sasha's favorite tools (Inito, LH strips, and progesterone testing) The age factor no one talks about enough: what the statistics actually say about childless-not-by-choice rates for women 35–40 and 40+ Premature ovarian insufficiency (POI): why some women enter early menopause between babies — and why waiting too long between pregnancies can dramatically change your options Tubal disease and endometriosis: how tubes that were once open can become blocked between pregnancies, and what an HSG actually involves Uterine factors: fibroids, polyps, Ashman syndrome, and why a saline infusion sonogram catches what a regular ultrasound misses Male factor infertility: why "he already has kids" is not a reason to skip the semen analysis, and how sleep deprivation, weight gain, and lifestyle changes after baby can tank sperm quality Unexplained secondary infertility: why it's the most frustrating diagnosis, and how Dr. Sasha expands her workup to look for hidden endometriosis, insulin resistance, and sleep disruption C-sections and fertility: what a meta-analysis of 600,000 women found about C-section's impact on subsequent pregnancy and live birth rates Isthmocele explained: what it is, how a C-section scar defect can trap fluid and create a hostile environment for embryos, and how it's diagnosed and treated Why Dr. Sasha pursued a VBAC after her first C-section — and the fertility reasoning behind that decision The full diagnostic workup for secondary infertility: what your doctor should be evaluating and what to ask for if they're not Treatment options: from super ovulation with IUI to IVF, to surgical correction of structural issues — and how the approach depends entirely on what the workup reveals Why breastfeeding may be the simplest thing standing between you and your next pregnancy Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more! Thank you to our sponsors! If you're in the infant stage or know someone who is, check out the Momcozy Night Pro Bottle Warmer or the DeepClean Bottle Washer D8. They're offering 20% off if you go to momcozy.com and use code TRYING. For a limited time, our listeners get $20 off to unlock their new health intelligence. Head over to Superpower.com and use code TRYING for $20 off your $199 Superpower membership. Learn more about your ad choices. Visit megaphone.fm/adchoices

  3. 29 Jul

    The Truth About Cycle Syncing, Fasted Training & Building Muscle After 40

    Most women have been told at some point that their menstrual cycle should dictate how they train, that fasted workouts are wrecking their hormones, or that muscle-building becomes nearly impossible after 40. In this episode, Dr. Sasha Hakman sits down with researcher and women's health expert Dr. Lauren Colenso-Semple to separate what the science actually shows from what the fitness industry is selling. They break down why cycle syncing isn't backed by the data, whether fasted training really matters, how much protein your body can actually use at once, and what's really true (and not true) about building muscle in perimenopause and menopause. If you've ever felt confused, discouraged, or like you needed to buy one more program to finally "get it right," this episode is for you. In this episode, we cover: Why the fitness industry profits from confusion — and how "cycle syncing" programs oversell the effect of hormones on your training Fasted vs. fed training: does it affect fat loss, muscle growth, or strength adaptations? (Spoiler: no) Low energy availability explained — who's actually at risk, and why it's different from simply training fasted The truth about the "anabolic window" and post-workout protein timing How much protein your body can actually use in one sitting, and why more isn't always better Why weight training under stable, loaded conditions beats unstable-surface or "functional" exercises for building muscle Understanding "the neighborhood of failure" — how close to failure you really need to train, and how to get started if you're intimidated by the weight room Rep ranges myths: why sets of 5 and sets of 25 can build the same amount of muscle Does the menstrual cycle affect training performance or adaptation? What the actual research says (not the extrapolated animal studies) Hormonal birth control, "brain changes," and exercise capacity — what's real and what's not Why so much of exercise science excluded women — and why that gap is closing faster than the internet gives it credit for Testosterone and muscle growth: why massive differences in testosterone levels between men and women don't translate to massive differences in ability to build muscle Can you make up for "lost time" if you didn't start lifting until your 40s, 50s, or later? Menopause and muscle: does estrogen decline really make it harder to build muscle, and does hormone therapy change that? Supplements that are actually worth your money — creatine dosing, why BCAAs are a waste, and why collagen is a poor protein source for muscle Whey vs. pea protein, jumping for bone health, and whether weighted vests actually do anything The single biggest myth stopping women from reaching their fitness goals Follow Dr. Lauren Colenso-Semple! Instagram: @drlaurencs1 Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more! Thank you to our sponsors!  Use code DRSASHA at ⁠carawayhome.com⁠ for 10% off Head to https://airdoctorpro.com/ and use promo code DRSASHA and get up to $300 off ANY of their select AirDoctor models, plus you will get a 3-year warranty,absolutely FREE!  All AirDoctor air purifiers come with a 30-day money back guarantee.  Get this exclusive, podcast-only offer NOW at https://airdoctorpro.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

  4. 22 Jul

    What IVF Protocol Did a Fertility Doctor Choose for Herself?

    You asked for it, and here it is. In this solo episode, Dr. Sasha Hakman walks through her own two IVF cycles in full detail — the exact medications, doses, trigger decisions, lab outcomes, and the reasoning behind every choice she made. As a reproductive endocrinologist who has navigated IVF both as a clinician and a patient, she brings a level of transparency you rarely get from a doctor. From a purely elective embryo freeze at 32 to a second retrieval at 37, this episode breaks down what actually goes into building a family through IVF — and helps you understand your own protocol along the way. In this episode, we cover: Why Dr. Sasha chose to freeze embryos at 32 — before she was ready to have children — and the reasoning behind creating embryos vs. freezing eggs Her diagnosis of Non-Classical Congenital Adrenal Hyperplasia (NCAH), what it is, and how it contributed to her ovulatory dysfunction Her baseline fertility stats: AMH of 4 ng/mL and 30+ follicles — even while on continuous birth control pills Cycle 1 at age 32: antagonist protocol, 275 units of Gonal-F + 75 units of Menopur, and why she chose a combination Lupron + low-dose hCG trigger The OHSS she developed after her first retrieval — how bad it got, and how she managed it at home Why she got 26 eggs but only 11 were mature — and why she was so disappointed with that outcome Cycle 2 at age 37: what changed in her protocol, and what the data from cycle 1 taught her Final embryo outcome: 6 blastocysts, 3 euploid (1 male, 2 female), 3 aneuploid ICSI — why she chose it even without a male factor diagnosis, and the case for doing it even when sperm looks great Assisted hatching — what it is, why she opted in, and the small but real risk of monozygotic twinning PGT-A genetic testing — how it works and why she would never transfer an aneuploid embryo Delayed vs. immediate egg stripping — an inside look at embryology lab practices most patients never hear about What she did NOT add to her protocol — no growth hormone, no embryo glue — and why she kept it evidence-based and simple The future of IVF: personalized genetic protocols that could one day predict how your ovaries will respond before your first injection Pregnancy update: 23 weeks, scheduled for a fetal echo, and feeling every bit of the third trimester Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more! Thank you to our sponsors!  Head to AquaTru.com now and get 20% off your purifier using promocode DRSASHA  Thanks to today’s sponsor, Ogee: A higher standard for beauty. Go to ogee.com/DRSASHA and use code DRSASHA to get 20% off certified organic makeup that performs like luxury. Support your cells and how you age with Mitopure® Gummies from Timeline. Visit timeline.com/SASHA and 20% off your Mitopure® Gummies. That’s timeline.com/SASHA. Learn more about your ad choices. Visit megaphone.fm/adchoices

  5. 15 Jul

    Does a Hysterectomy Cure Endometriosis? An Endo Surgeon Answers Your Top Googled Questions

    Endometriosis affects at least 1 in 10 women, yet the average patient waits years for a diagnosis — often after being told their pain is normal. In this episode, Dr. Sasha Hakman sits down with board-certified OB/GYN and endometriosis surgeon Dr. Mallory Stuparich to break down what endometriosis actually is, why it's now understood as a systemic immune and neuro-inflammatory condition rather than a purely hormonal one, and how patients can push back when they're being dismissed. If you've ever been told your pain is "just part of being a woman," this episode is for you. In this episode, we cover: What endometriosis actually is — and why "endometrial-like tissue" outside the uterus is now understood as part of a systemic neuro-inflammatory and neuro-immune disorder, not just a hormonal one Why endometriosis so often overlaps with mast cell activation, POTS, Ehlers-Danlos syndrome, autoimmune conditions, and migraines The leading theories on what causes endometriosis, and why retrograde menstruation alone doesn't explain it Normal period pain vs. abnormal period pain — and the questions to ask yourself to know the difference Red flag symptoms beyond pelvic pain: GI issues (painful bowel movements, incomplete emptying, bleeding), bladder urgency, pelvic floor dysfunction, painful sex, and brain fog Why the amount of pain a patient feels doesn't always correlate with how much disease is actually present What a real diagnostic workup looks like, and why a "normal" ultrasound or MRI does not rule out endometriosis Post-surgical hormone therapy — why suppression after excision matters, and who isn't a candidate Adenomyosis explained: what it is, how it differs from fibroids, and treatment options including adenomyomectomy, uterine artery embolization, and microwave ablation The links between endometriosis, infertility, and miscarriage — including why 50% of women with endo do not experience infertility Recurrence after excision surgery, and why what looks like "recurrence" is often incomplete removal the first time around Lightning round: Is endometriosis genetic? Can you have it with completely normal labs and imaging? Does a hysterectomy cure it? Can it still affect you after menopause? Follow Dr. Mallory Stuparich! Instagram/social: @MalloryStuparichMD Follow Dr. Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingpod YouTube: @sashahakmanmd Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more! Thank you to our sponsors!  Head to bioptimizers.com/drsasha and use code DRSASHA try OneSkin with 15% off using code DRSASHA at oneskin.co/DRSASHA Head to vitaclean.co and use code DRSASHA for 20% off Shower head Starter Kits Learn more about your ad choices. Visit megaphone.fm/adchoices

  6. 8 Jul

    What Causes Miscarriage? A Fertility Doctor's Full Breakdown

    Pregnancy loss affects 15–25% of clinically recognized pregnancies, yet so many people are left without answers — or without hope. In this solo episode, Dr. Sasha Hakman breaks down everything you need to know about miscarriage and recurrent pregnancy loss: the five major causes, how each one is diagnosed, what treatment actually looks like, and which lifestyle factors are (and aren't) worth worrying about. If you've experienced a loss and are searching for answers, this episode is for you — and remember, it is not your fault. In this episode, we cover: Why miscarriage is so common, and how the definition of "recurrent pregnancy loss" has evolved to include biochemical losses Bucket 1 — Genetic/Chromosomal causes: why random chromosomal errors (like trisomy 16 and Turner syndrome) account for up to 75% of losses, the U-shaped age-risk curve, and when to test for balanced translocations via karyotype Bucket 2 — Anatomic causes: uterine septums, scar tissue (Asherman syndrome), fibroids, polyps, adenomyosis, and how they're diagnosed via saline infusion sonogram or HSG Bucket 3 — Immune/Autoimmune causes: antiphospholipid syndrome (APS), the antibodies involved, and why diagnostic criteria may lag behind clinical reality Bucket 4 — Endocrine causes: thyroid dysfunction, high prolactin, insulin resistance/diabetes, PCOS, and luteal phase defects The "5th bucket": unexplained pregnancy loss — and additional testing some REs order beyond ASRM guidelines (clotting disorders, chronic endometritis, vaginal microbiome) Treatment options by diagnosis, including PGT-SR, Lovenox + baby aspirin for APS, metformin, and surgical correction of uterine abnormalities Modifiable risk factors: smoking, alcohol, caffeine (the real data), weight/GLP-1 agonists, sleep, sedentary behavior, and why stress is often unfairly blamed The encouraging stats: a 70% live birth rate in the pregnancy following a loss, and how high-touch prenatal care can improve outcomes Follow Dr. Sasha!  TikTok: @sashahakmanmd  Instagram: @sashahakmanmd @tryingpod  YouTube: @sashahakmanmd Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more! Thank you to our sponsors!  Head to cozyearth.com and use my code DRSASHA for an exclusive 20% off. Use code DRSASHA at carawayhome.com for 10% off Subscribe, rate, and review if this episode helped you — and share it with someone who needs to hear it. New episodes drop every Wednesday. Learn more about your ad choices. Visit megaphone.fm/adchoices

  7. 1 Jul

    Fertility After 40: Real Stats, Real Options, Real Talk

    In this solo episode, Dr. Sasha dives into one of the most requested topics on the podcast: trying to conceive and being pregnant after 40. She cuts through the noise of misleading celebrity headlines and online misinformation to give you a clear, honest, and compassionate look at the biology, statistics, and real options available to you. In This Episode, You'll Learn: Why more women are having babies in their 40s than ever before — and why that's a good thing The biology of egg aging: how quantity and quality decline, and what's actually happening at the cellular level (mitochondrial dysfunction, meiosis errors, chromosomal abnormalities) What your AMH level means after 40, and why high ovarian reserve can be a game-changer Natural fertility rates by age and when ASRM guidelines say to seek immediate care IVF success rates broken down by age: from 43% live birth rate under 35, all the way down to 3% over 42 Follow Dr. Sasha!  TikTok: @sashahakmanmd  Instagram: @sashahakmanmd @tryingpod  YouTube: @sashahakmanmd Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter for updates, Q&A answers and more! If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every week. If you're interested in becoming a patient go to sashahakmanmd.com to learn more! Thank you to our sponsors!  Save 20% Off Honeylove by going to honeylove.com/DRSASHA! #honeylovepod For a limited time, try OneSkin with 15% off using code DRSASHA at oneskin.co/DRSASHA. Head to AirDoctorPro.com and use promo code DRSASHA to get $250 off select AirDoctor air purifiers, including the 3500, 4000, and 5500 models New episodes of Trying with Dr. Sasha Hakman drop weekly. If this episode resonated with you, leave a review and share it with someone who needs a doctor they can trust in their corner. Learn more about your ad choices. Visit megaphone.fm/adchoices

  8. 24 Jun

    The IVF Test That Could Finally Explain Your Failed Transfers with Jeremy Grushcow of Juniper Genomics

    If you've ever gone through a failed embryo transfer and wondered why , this episode is for you. Dr. Sasha sits down with Jeremy Grushcow, co-founder and CEO of Juniper Genomics, to break down a groundbreaking advancement in IVF: whole genome and transcriptome embryo testing. Jeremy holds a PhD in molecular genetics and cell biology from the University of Chicago, along with a law degree, and has published research in DNA repair, cancer, gene therapy, bioethics, and patent law. He's building the technology that could change the odds for IVF patients everywhere. In this episode, we cover: What whole genome sequencing actually is — and why IVF has lagged behind every other field of clinical medicine in adopting it The brilliant "books on a shelf" analogy that finally makes PGT-A vs. whole genome sequencing click Why failed embryo transfers are not your fault, your doctor's fault, or your lab's fault — and what the embryo's genetics have to do with it What the transcriptome tells us that the genome alone can't The difference between PGT-A, PGT-M, and Juniper's PGT-G testing How Juniper looks at both the embryo and the parents' DNA to identify where variants are coming from (egg or sperm?) The 6,000+ known genetic diseases — and why 10–15% of embryos being transferred today carry a detectable single-gene disorder that standard carrier screening missed Why "reduced viability variants" matter and how they impact IVF success rates The emotional and financial cost of failed transfers — and how more information can reduce both Pricing breakdown: what Juniper's PGT-A and PGT-G costs, how to make it more affordable, and how it stacks up against the cost of a failed transfer cycle Why patient autonomy in the US and Canada is driving better IVF outcomes globally Follow Dr Sasha! TikTok: @sashahakmanmd Instagram: @sashahakmanmd @tryingwithdrhakman YouTube: @sashahakmanmd Resources & Links: Juniper Genomics website: junipergenomics.com Instagram: ⁠@junipergenomics⁠ Want to receive my weekly newsletter? Sign up at sashahakmanmd.com/newsletter to receive updates, answers to Q&A and more !If you haven't already, please rate, review, and follow the podcast to be notified of new episodes every 2 weeks. If you're interested in becoming a patient go to sashahakmanmd.com to learn more! If this episode helped you, the best thing you can do is subscribe, rate, review, and share it with a friend. So many women deserve this information, help get it to them. Episodes drop every Wednesday. Learn more about your ad choices. Visit megaphone.fm/adchoices

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Trailer

About

As a double board-certified OB-GYN and Reproductive Endocrinology and Infertility specialist, I've dedicated my career to helping women understand and navigate their reproductive health, but my passion for this podcast goes beyond my clinical background. My own personal experience with infertility gives me a firsthand understanding of the emotional and physical weight of this journey, and it's what drives me to show up for this community every week. Trying with Dr. Sasha Hakman has grown because the conversation needed to grow too. Yes, we still cover the trying-to-conceive journey: the IUIs, the IVFs, the unexplained infertility, the grief, and the hope. But we also go deeper: hormones, PCOS, endometriosis, thyroid health, perimenopause, egg freezing, cycle tracking, and everything in between. Every episode, I break down complex science in plain language with no jargon, no shame, no sugarcoating, through expert interviews, real patient stories, and the latest innovations in women's health. Because the more you understand your body, the more power you have.

Information

  • Channel
    Pursuit Network
  • Creator
    Dr Sasha Hakman
  • Years Active
    2025 - 2026
  • Episodes
    48
  • Rating
    Explicit
  • Provider
    Pursuit Network

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