Modern Thyroid and Wellness

McCall McPherson, PA-C

Unlock the latest insights into thyroid health and wellness with McCall McPherson, PA-C. Through expert interviews, personal stories, and actionable advice, this podcast dives deep into thyroid disorders, exploring how they impact everything from energy levels to mental clarity. Whether you're navigating your own thyroid journey or seeking cutting-edge solutions for optimal health, you'll find practical tips and holistic strategies to support your well-being. Join McCall as she empowers listeners to take control of their thyroid health and live a more vibrant life.

  1. 76: Your Gut Might Be Blocking Your Hormones – Why You Still Feel Bad Despite Normal Labs with Cassie Smith

    13 HR AGO

    76: Your Gut Might Be Blocking Your Hormones – Why You Still Feel Bad Despite Normal Labs with Cassie Smith

    What if your symptoms aren’t because your hormones are “wrong”—but because your body can’t actually use them? In this episode of Modern Thyroid and Wellness, McCall McPherson sits down with Dr. Cassie Smith, board-certified endocrinologist and Chief Medical Director at Modern Thyroid Clinic, to uncover the powerful connection between gut health, inflammation, and hormone function. Dr. Smith shares why so many women continue to feel exhausted, inflamed, and out of balance—even when their labs look “normal.” This conversation reveals how gut dysfunction drives inflammation, blocks hormone activity at the cellular level, and creates a cycle that conventional medicine often misses. 🔑 Key Topics Covered Why “normal labs” don’t always mean optimal healthHow gut inflammation prevents hormones from working at the cellular levelThe bidirectional relationship between gut health and hormonesEarly warning signs of gut dysfunction (beyond digestion)How chronic stress damages the gut microbiomeThe connection between cortisol, insulin, and hormone imbalanceWhy women in their 30s and 40s experience worsening symptomsHow gut health impacts thyroid hormone conversion and absorptionThe role of inflammation in weight gain, fatigue, and brain fogHow microdosed GLP-1 can help break the inflammation cycle 🧠 The Gut–Hormone Connection Explained Hormones don’t just need to be present—they need to enter your cells and function properly. When inflammation is high: Hormone receptors become resistantHormones cannot enter the cell effectivelySymptoms persist—even with “perfect” lab results 👉 This is why many women feel stuck despite treatment 🔁 The Cycle No One Explains This dysfunction creates a loop: Stress, diet, and lifestyle disrupt the gutGut imbalance (dysbiosis) increases inflammationInflammation raises cortisol and insulinHormone production (estrogen, progesterone, testosterone) declinesHormone imbalance worsens gut health 👉 The cycle reinforces itself unless the root cause is addressed 🚨 Signs Your Gut Could Be the Root Cause You may not have obvious digestive issues—but your gut could still be involved. Common signs include: Bloating or acid refluxConstipationBrain fogFatigueAnxiety or depressionSkin issuesWeight gain or resistanceHormonal imbalance 👉 Multiple symptoms across systems often point back to gut dysfunction 🦋 Thyroid, Gut & Cellular Function Gut health is critical for thyroid patients. Most T4 → T3 conversion happens in the gutInflammation blocks T3 from entering cellsAutoimmune activity increases inflammation 👉 Even with proper thyroid medication, symptoms may persist if the gut is not addressed 🔥 Inflammation Is the Real Problem Inflammation is often invisible—but it affects everything: Energy levelsHormone functionBrain clarityWeight regulation As Dr. Smith emphasizes, inflammation is not just a concept—it’s something you feel daily. ⚖️ Insulin, Cortisol & Metabolic Dysfunction Gut-driven inflammation leads to: High insulin → fat storageHigh cortisol → hormone suppressionLow estrogen and progesterone 👉 This results in: Midsection weight gainIncreased hungerDifficulty losing weight 💉 GLP-1 and Breaking the Cycle One of the most powerful tools discussed: Microdosed GLP-1 therapy When used correctly, it can: Lower inflammation rapidlyReduce insulin levelsImprove hormone signalingSupport gut healing 👉 The key is low, physiologic dosing 🌱 Where to Start Instead of increasing hormone doses endlessly, focus on: Reducing inflammationSupporting gut healthImproving metabolic functionRestoring hormone signaling Foundational strategies: Prioritize sleep (7–9 hours)Manage stressStay hydratedIncorporate movementSupport gut health through diet 📘 About the Guest Dr. Cassie Smith is a dual board-certified endocrinologist in endocrinology, diabetes, metabolism, and internal medicine, and the founder of Modern Endocrine. She is known for her root-cause, whole-body approach to hormone health, focusing on gut health, metabolism, and inflammation to help patients feel better beyond “normal labs.” She also serves as Chief Medical Director at Modern Thyroid Clinic, where she helps guide advanced, patient-centered protocols for complex thyroid and hormonal cases. 🌐 Resources & Links 🌐 Modern Thyroid Clinic Profile: https://www.modernthyroidclinic.com/cassie-smith 🌐 Modern Endocrine About Page: https://www.modern-endocrine.com/about/ 📲 Follow McCall McPherson & Modern Thyroid and Wellness 💻 Website: modernthyroidclinic.com 🐦 X / Twitter: @thyroidexpert 🌐 Host Website: mccallmcpherson.com 📺 YouTube: McCall McPherson Channel 📘 Facebook: McCall McPherson PAC 📸 Instagram: @mccallmcphersonpa

    37 min
  2. 75: Fertility Isn’t Just Luck – How Hormones, Thyroid, and Lifestyle Shape Your Ability to Get Pregnant with Natalie Crawford

    2 APR

    75: Fertility Isn’t Just Luck – How Hormones, Thyroid, and Lifestyle Shape Your Ability to Get Pregnant with Natalie Crawford

    What if your fertility challenges weren’t random—but your body signaling deeper imbalances that can actually be addressed? In this episode of Modern Thyroid and Wellness, McCall McPherson sits down with Natalie Crawford, a board-certified reproductive endocrinologist and infertility expert, to break down the real drivers behind fertility struggles. Dr. Crawford shares a powerful, root-cause approach to fertility, explaining how your menstrual cycle acts as a vital sign, how thyroid health and inflammation play a major role, and why modern lifestyle factors are significantly impacting fertility outcomes. This conversation is both eye-opening and deeply empowering for women who want to better understand their bodies and take control of their reproductive health. 🔑 Key Topics Covered The rising rates of infertility and what’s driving the increase Why your menstrual cycle is a key indicator of hormonal health What a “normal” cycle actually looks like (and common red flags) How to accurately track ovulation using simple, effective methods The connection between thyroid health and fertility outcomes Why Subclinical Hypothyroidism is often missed—but critical How inflammation impacts egg quality, hormones, and conception The role of gut health and the microbiome in fertility Why insulin resistance affects fertility—even without diabetes How stress, sleep, and lifestyle directly influence reproductive health 🩺 Understanding Your Cycle (Your Hormonal Blueprint) Your menstrual cycle is one of the most important tools for understanding your fertility. Each month, your body moves through two key phases: Follicular phase: Estrogen rises, the egg matures, and energy increasesLuteal phase: Progesterone supports potential pregnancy Ovulation occurs in between—and timing matters more than most people realize. 👉 A healthy cycle should be: Predictable (within 1–2 days each month)Consistent in ovulationSupported by a stable luteal phase 🚩 Warning signs include: Irregular cyclesShort luteal phasesSpotting before your periodDifficulty identifying ovulation 🧪 Tracking Ovulation (Without Relying on Labs) Dr. Crawford emphasizes that lab testing alone is often not enough. Instead, your body gives you clear signals: Cervical mucus (egg-white consistency = ovulation)LH urine testing (best between 10 AM–2 PM)Basal body temperature or wearable tracking 👉 Even one tracking method improves fertility awareness 👉 Combining methods increases accuracy significantly 🦋 The Thyroid–Fertility Connection Thyroid health is one of the most overlooked drivers of fertility issues. Even when labs appear “normal,” your body may still be under stress. This is known as Subclinical Hypothyroidism Key insights: The brain may be signaling for more thyroid hormone even if labs look normalThis reflects underlying inflammation and imbalanceIt is linked to:InfertilityMiscarriageHormonal dysfunction 👉 During pregnancy, your body needs 30% more thyroid hormone If your system is already strained, it may not be able to meet this demand 🔥 Inflammation: The Root Cause You Can’t Ignore One of the biggest themes in this episode is the role of inflammation. Chronic inflammation can: Damage egg qualityDisrupt hormone signalingImpair mitochondrial function (critical for embryo development) Modern contributors include: Processed foodsEnvironmental toxinsPoor sleepChronic stress 🦠 Gut Health & Fertility Your gut plays a central role in regulating inflammation and hormones. When gut health is compromised: Hormone metabolism becomes disruptedInflammation increasesFertility outcomes decline Key factors impacting gut health: Low fiber intakeUltra-processed foodsImbalanced microbiome 👉 Fiber-rich foods are essential for supporting a healthy gut and hormone balance 🍬 Insulin Resistance (Even If You’re “Healthy”) Insulin resistance is not just a diabetes issue—it’s a fertility issue. It can: Disrupt ovulationIncrease inflammationLower IVF success ratesIncrease miscarriage risk Even women without PCOS or diabetes can be affected. 💪 Why Muscle, Stress & Sleep Matter Muscle Health Building muscle helps regulate blood sugar without relying on insulin, improving hormonal balance. Stress Chronic stress raises cortisol, which increases inflammation and disrupts fertility signals. Sleep Sleep is one of the most powerful tools for hormone regulation. 👉 Aim for 7–9 hours per night to support recovery, hormone balance, and fertility 🌱 Pre-Pregnancy Planning (The Missing Strategy) Instead of waiting until something goes wrong: 👉 Start preparing your body before trying to conceive This includes: Optimizing thyroid healthReducing inflammationSupporting gut healthTracking your cycleBuilding healthy lifestyle habits Fertility is not just about pregnancy—it’s a reflection of long-term health. 🌐 Resources & Links 🌐 Website: https://www.nataliecrawfordmd.com 📘 Book: The Fertility Formula by Natalie Crawford 📲 Follow McCall McPherson & Modern Thyroid and Wellness 💻 Website: modernthyroidclinic.com 🐦 X / Twitter: @thyroidexpert 🌐 Host Website: mccallmcpherson.com 📺 YouTube: McCall McPherson Channel 📘 Facebook: McCall McPherson PAC 📸 Instagram: @mccallmcphersonpa

    45 min
  3. 74: The Future of Medicine May Not Be Medication - How Stem Cells and Regenerative Therapy Are Changing Healing with Dr. Karolynn Halpert

    26 MAR

    74: The Future of Medicine May Not Be Medication - How Stem Cells and Regenerative Therapy Are Changing Healing with Dr. Karolynn Halpert

    What if the future of medicine isn’t about managing symptoms—but actually helping the body rebuild and heal itself? In this episode of Modern Thyroid and Wellness, McCall McPherson sits down with Dr. Karolynn Halpert, a regenerative medicine specialist at BioXcellerator, to explore the powerful and rapidly evolving world of stem cell therapy. Dr. Halpert shares her journey from emergency medicine to regenerative care, and explains how stem cells and exosomes are being used to reduce inflammation, restore function, and support healing in conditions ranging from spinal cord injuries to autoimmune disease, infertility, and neurological disorders. This conversation dives deep into what stem cells actually are, why treatment options differ drastically between the U.S. and countries like Colombia, and how regenerative medicine may reshape the future of longevity, hormones, and chronic disease care. 🔑 Key Topics Covered The difference between conventional medicine and regenerative medicineWhat stem cells and exosomes are—and how they actually workWhy inflammation is a key driver of aging and chronic diseaseHow stem cells help regulate the immune system and promote healingWhy stem cell therapy is limited in the U.S. compared to other countriesThe difference between autologous (your own) stem cells vs. cultured stem cellsWhy BioXcellerator uses a combination of stem cells and exosomesHow specialized delivery (like intrathecal injections) improves outcomesReal patient transformations, including spinal cord injury and autism casesThe role of stem cells in fertility, hormone balance, and perimenopauseWhy lifestyle still matters—even with advanced therapies 🧠 What Are Stem Cells (And Why They Matter) Regenerative medicine focuses on helping the body repair itself rather than simply treating symptoms. According to Dr. Halpert: Stem cells reduce inflammationThey modulate the immune systemThey signal the body to repair damaged tissueThey work through cell signaling (paracrine effects) rather than just replacing cells Exosomes, on the other hand, are tiny vesicles released by stem cells that carry healing signals—but unlike stem cells, they are not alive and cannot adapt to their environment. 👉 At BioXcellerator, combining both creates a powerful effect: Exosomes = fast results (short-term)Stem cells = long-term regeneration (up to 12–18 months) 🌍 Why People Travel for Stem Cell Therapy One of the most important distinctions discussed: In the United States: Only your own stem cells can be usedNo expansion (limited quantity)Often lower potency due to age, health, and inflammation At BioXcellerator: Stem cells are cultured and expanded in a labTens to hundreds of millions of cells can be usedHigher quality, younger, more functional cells 👉 This creates a significant difference in outcomes and effectiveness. 🧬 Real Patient Transformations Dr. Halpert shares powerful real-life cases: 🦽 Spinal Cord Injury Patient paralyzed from the neck downAfter treatment: regained hand movement, independence, and ability to hold his child 🧠 Autism Non-verbal child began speaking, making eye contact, and engaging socially These cases highlight what may be possible when regenerative medicine is applied with precision and specialization. 👩‍⚕️ Hormones, Fertility & Women’s Health Stem cells are also being explored in: Perimenopause & menopauseReducing inflammationImproving energy, sleep, and moodFertilitySupporting ovarian functionImproving uterine environment for implantationIVF success ratesEvidence suggests higher success when stem cells are used beforehand Early patient feedback shows: Better hormonal stabilityReduced symptomsImproved response to hormone therapy 🦋 Autoimmune Conditions & Thyroid Insight While research is still emerging, one key takeaway: Stem cells may help modulate autoimmune activityThis could potentially benefit conditions like Hashimoto’s However, more clinical data is still needed, especially for thyroid-specific outcomes. ⚠️ Common Misconceptions About Stem Cells A major myth addressed in the episode: ❌ All stem cells come from embryos ✔️ Many (including those used at BioXcellerator) come from umbilical cord tissue, a discarded, ethical source Other misconceptions: Not all stem cells are equalQuality, source, and processing matter significantlyProtocols and delivery methods impact results 🌱 The Bigger Message: You Still Have to Do the Work Dr. Halpert emphasizes something critical: Regenerative medicine works best when paired with lifestyle changes. Key factors: NutritionSleepStress managementReducing chronic inflammation Stem cells are not a shortcut—they are a powerful tool layered on top of a healthy foundation. 🌐 Resources & Links 🌐 Website: BioXcellerator Official Website👤 Guest: Dr. Karolynn Halpert🔗 LinkedIn: Karolynn Halpert LinkedIn Profile 📲 Follow McCall McPherson & Modern Thyroid and Wellness 💻 Website:a href="https://modernthyroidclinic.com/"...

    52 min
  4. 73: Sauna Science Explained: Infrared vs. Traditional, Detox, Heart Health, and What to Look For with Connie Zack

    19 MAR

    73: Sauna Science Explained: Infrared vs. Traditional, Detox, Heart Health, and What to Look For with Connie Zack

    What if sauna therapy supports more than relaxation, influencing detoxification, circulation, and long-term health? In this episode of Modern Thyroid and Wellness, McCall McPherson sits down with Connie Zack, co-founder of Sunlighten, to unpack the science, strategy, and real-world benefits of sauna therapy. Connie shares the deeply personal story that led her and her husband to leave careers in pharmaceutical sales and build Sunlighten after seeing infrared therapy transform her brother’s health. Connie and her husband started Sunlighten more than 20 years ago after her brother’s life changed through infrared light therapy, and the company continues to focus on science-backed infrared sauna technology. Together, McCall and Connie break down the differences between traditional saunas and infrared saunas, why all infrared saunas are not created equal, what far infrared actually does inside the body, and how sauna use can support cardiovascular health, detoxification, skin, nervous system regulation, and overall longevity. They also discuss red light therapy, what to look for when shopping for a sauna, and how to think about sauna use as a practical part of a wellness routine. This episode is a helpful guide for anyone curious about sauna therapy and wanting a clearer, more evidence-informed understanding of how to choose the right sauna and use it well. Episode Highlights Connie Zack’s personal story of how her brother’s chronic illness led her into the world of infrared light and sauna therapyWhy Connie and her husband left stable pharmaceutical careers to build SunlightenThe difference between traditional saunas and infrared saunasHow traditional saunas heat the air, while infrared heats the body more directlyWhy far infrared is the foundational wavelength in infrared sauna therapyWhy all infrared saunas are not the same and what consumers should watch out forWhy heater surface temperature matters more than cabin air temperature in infrared sauna performanceThe importance of low EMF design and non-toxic building materialsHow infrared sauna use may support detoxification, circulation, and skin healthWhy combining far infrared, near infrared, and red light creates a more complete wellness experienceThe role of red light and near infrared light in supporting collagen, skin repair, and cellular energyWhy Connie considers sauna use one of the best whole-body longevity tools availableResearch discussed around cardiovascular health, blood pressure, nervous system support, and long-term wellnessHow sauna can support a shift from sympathetic stress mode into a more parasympathetic, restorative stateConnie’s approach to habit stacking and using sauna time intentionallyThe differences between Sunlighten’s Solo, Signature, Amplify, and mPulse collectionsWhy the Sunlighten red light panel and mask may be useful tools for skin, recovery, and wellness routines Resources & Links Sunlighten: https://www.sunlighten.com/Connie Zack LinkedIn: https://www.linkedin.com/in/conniezack/ 📲 Follow McCall McPherson & Modern Thyroid and Wellness 💻 Website: modernthyroidclinic.com 🐦 X / Twitter: @thyroidexpert 🌐 Host Website: mccallmcpherson.com 📺 YouTube: McCall McPherson Channel 📘 Facebook: McCall McPherson PAC 📸 Instagram: @mccallmcphersonpa

    44 min
  5. 72: When Thyroid Care Finally Starts Listening - Why Personalized Treatment Changes Everything with Yari Tran Melody Volz and Nikki Abelow

    12 MAR

    72: When Thyroid Care Finally Starts Listening - Why Personalized Treatment Changes Everything with Yari Tran Melody Volz and Nikki Abelow

    What if the reason many thyroid patients struggle is not the condition itself, but how thyroid care is traditionally approached? In this episode of Modern Thyroid and Wellness, McCall McPherson continues the clinician interview series by introducing three more members of the Modern Thyroid Clinic team: Yari Tran, PA-C, Melody Volz, FNP-C, and Nikki Abelow, APRN. Yari earned her psychology degree at Texas A&M and her physician assistant training at Texas Tech, then began in neurosurgery and pain management before shifting into root-cause thyroid and hormone care. Melody trained at the University of Texas at Austin, became a family nurse practitioner in 2014, and brings both clinical expertise and her own history of hypothyroidism and Hashimoto’s to patient care. Nikki, a Florida-based APRN, graduated from Chamberlain University in 2019 after working as a cardiac nurse and later pursued additional functional medicine training through the School of Applied Functional Medicine. This conversation gives listeners a behind-the-scenes look at how each clinician found their way into medicine, what changed their perspective on conventional thyroid care, and why they are so passionate about individualized treatment. Across all three interviews, a shared theme emerges: thyroid care is rarely simple, TSH alone is not enough, and patients deserve to feel seen, heard, and fully supported. Note About This Episode Hillary Mayers was originally scheduled to appear in this episode. Due to a technical error during recording and editing, we were unable to include her segment. We greatly value Hillary’s insights and expertise, and she will be featured in a dedicated solo episode in the future. Thank you for your understanding. We truly appreciate your patience and support as we navigate this, and we’re excited to continue bringing you meaningful content in Thursday’s episode. Episode Highlights Why this clinician interview series was created and what listeners can expect from future partsYari’s early love of medicine, from bringing an anatomy textbook to kindergarten show-and-tell to becoming a PAThe hormone conference that changed Yari’s entire view of thyroid and chronic symptom careWhy conventional, insurance-based models make nuanced thyroid treatment difficultYari’s take on one major misconception: thyroid treatment is never one-size-fits-allMelody’s personal story of being diagnosed with hypothyroidism and Hashimoto’s after struggling for answers as a teenagerHow Melody learned firsthand that “normal” labs do not always mean patients feel wellWhy Melody believes thyroid disease is not a life sentence when treated properlyNikki’s path from nursing into functional medicine after her own health challenges led her to question conventional careNikki’s experience of being told a TSH in the 3s was “normal” despite obvious symptomsWhy Nikki is passionate about creating generational health by educating mothers and daughters earlierThe shared message from all three clinicians: patients do better when care is personalized, symptom-aware, and root-cause focusedFun personal details, from Yari’s love of 80s and 90s country to Melody being a twin and Nikki’s love of cruising and Alaska In This Episode, You Will Learn Why many thyroid patients still struggle when care focuses only on TSHHow thyroid symptoms can be real even when standard labs appear “normal”Why full thyroid panels, thoughtful medication choices, and individualized dosing matterThe difference between treating Hashimoto’s and simply replacing thyroid hormoneWhy many women are dismissed with “you’re just tired,” “you’re just a mom,” or “it’s not your thyroid”How proper thyroid care can restore quality of life, energy, confidence, and hopeWhy clinicians who have lived through thyroid dysfunction themselves often bring deeper empathy to careHow Modern Thyroid Clinic’s approach combines education, empowerment, and precision About the Clinicians Yari Tran, PA-C began her medical career in neurosurgery and pain management before a hormone education conference reshaped her clinical perspective and sparked her passion for functional thyroid and hormone care. She lives in Austin with her two daughters and enjoys reading, running, and hiking. Melody Volz, FNP-C earned both her BSN and MSN from the University of Texas at Austin and became a certified family nurse practitioner in 2014. Her own experience with hypothyroidism and Hashimoto’s helped shape her patient-centered approach to thyroid and hormone care. Nikki Abelow, APRN is a Florida-based advanced practice registered nurse who came from a cardiac nursing background and later expanded into functional medicine after her own health challenges pushed her to look beyond conventional care. She lives in Florida with her husband and son. 📲 Follow McCall McPherson & Modern Thyroid and Wellness 💻 Website: modernthyroidclinic.com 🐦 X / Twitter: @thyroidexpert 🌐 Host Website: mccallmcpherson.com 📺 YouTube: McCall McPherson Channel 📘 Facebook: McCall McPherson PAC 📸 Instagram: @mccallmcphersonpa

    48 min
  6. 71: A Cancer Diagnosis Changed Everything - The Hidden Truth About Big Food and Metabolic Health with Patrick Sullivan Jr and Ashley Sullivan

    5 MAR

    71: A Cancer Diagnosis Changed Everything - The Hidden Truth About Big Food and Metabolic Health with Patrick Sullivan Jr and Ashley Sullivan

    What if the reason you still feel tired after optimizing hormones is not your hormones at all? In this episode, Michael sits down with Patrick Sullivan Jr. and Ashley Sullivan, the executive producers behind the new documentary Breaking Big Food: How the American Food System Went Rotten and How It's Being Revived. Their mission to expose the problems within the modern food system began with a deeply personal experience: Patrick’s thyroid cancer diagnosis. Patrick shares the emotional journey of discovering a lump in his neck, navigating multiple biopsies, and ultimately undergoing thyroid surgery. The experience sparked a deeper question that traditional medicine could not answer: why did cancer develop in the first place? That question ultimately led the couple into the world of metabolic health, food quality, and environmental influences on chronic disease. The conversation explores how processed foods, corporate food systems, and environmental toxins may contribute to widespread metabolic dysfunction, thyroid disease, and chronic illness. Patrick and Ashley also share insights from their documentary, including shocking discoveries about how tobacco companies once controlled a large portion of the American food supply. Inspired by their journey, the couple also launched Firefly Organic Coffee and Market, a Scottsdale-based café focused on mold-free organic coffee and nutrient-dense foods. This episode connects the dots between food, stress, environment, and long-term health while highlighting how personal pain can become a powerful purpose. 👤 About the Guests Patrick Sullivan Jr. Patrick Sullivan Jr. is an entrepreneur, filmmaker, and thyroid cancer survivor. After his diagnosis over a decade ago, he began exploring the deeper connections between food, environmental exposures, stress, and metabolic health. Patrick is the executive producer of the documentary Breaking Big Food, which investigates the history of the American food system and its impact on chronic disease. Ashley Sullivan Ashley Sullivan is a business owner, producer, and wellness advocate who works alongside Patrick in both their film and food initiatives. She co-produced Breaking Big Food and co-founded Firefly Organic Coffee and Market, a Scottsdale café dedicated to providing organic, mold-free coffee and access to nutrient-dense foods that support better health. 🔑 Key Topics Covered Patrick’s thyroid cancer diagnosis and the stress of navigating uncertain test resultsWhy thyroid cancer often raises deeper questions about environmental and lifestyle factorsThe emotional and physical impact of living with a cancer diagnosisThe influence of chronic stress on metabolic and thyroid healthHow food quality can influence inflammation and long-term disease riskThe surprising history of tobacco companies acquiring major food brands in the 1980sWhy processed foods are engineered to be addictiveThe connection between metabolic dysfunction and the modern food systemSmall dietary changes that can dramatically improve health outcomesThe inspiration behind the documentary Breaking Big FoodLaunching Firefly Organic Coffee and Market to provide clean food optionsThe issue of mold contamination in coffee and why sourcing matters 🎬 Resources and Links Mentioned 📺 Watch the Documentary Breaking Big Food: How the American Food System Went Rotten and How It's Being Revived Available on Apple TV and Amazon Prime Video 📲 Follow McCall McPherson & Modern Thyroid and Wellness 💻 Website: modernthyroidclinic.com 🐦 X / Twitter: @thyroidexpert 🌐 Host Website: mccallmcpherson.com 📺 YouTube: McCall McPherson Channel 📘 Facebook: McCall McPherson PAC 📸 Instagram: @mccallmcphersonpa

    33 min
  7. 70: Normal Labs but Still Miserable - Why Symptom Driven Thyroid Care Changes Everything with Brandy Valentino, Jessica Strauss and Krystal Adams

    26 FEB

    70: Normal Labs but Still Miserable - Why Symptom Driven Thyroid Care Changes Everything with Brandy Valentino, Jessica Strauss and Krystal Adams

    What if the reason many thyroid patients still feel unwell is not their labs, but how their symptoms are being interpreted? Today’s episode is the first installment of a multi-part clinician interview series on the Modern Thyroid Clinic podcast. Host McCall McPherson sits down with three of the clinic’s clinicians, Brandy Valentino, RN, WHNP, CNM, Jessica Strauss, DNP, FNP-C, and Krystal Adams, MSN, FNP-BC, LSO, to help listeners get to know the people behind the care. Together, they share their personal journeys into medicine, what led them to thyroid and hormone work, and why individualized, symptom-driven care matters so much for thyroid patients. You will also hear candid conversations about medical gaslighting, obesity bias, the limitations of TSH-only testing, and why many people with “normal labs” still feel miserable. Along the way, the episode brings plenty of personality and behind-the-scenes stories, including Brandy’s early inspiration from a care flight helicopter tour, Jessica’s love of travel and Disney, and Krystal’s surprising connection to a military dolphin trainer story. Episode Highlights Why this clinician interview series was created and what to expect in future partsBrandy’s story of being inspired in third grade by a care flight helicopter visitBrandy’s background in labor and delivery, women’s health, and midwiferyHow Brandy transitioned into thyroid care after questioning algorithm-based hormone protocolsWhat Brandy finds most meaningful: the “fast forward” moment when patients get their lives backThe misconception Brandy wants patients to understand: thyroid care is highly individualizedThe reality of being dismissed with “it’s not your thyroid” and why that harms patientsJessica’s personal experience of thyroid symptoms despite consistently “normal” TSHHow Jessica’s training included a more nuanced view beyond basic thyroid teachingA powerful story: antibodies rising dramatically and an endocrinology response of “nothing different to do”How obesity bias impacts care and how it can delay diagnosis and worsen outcomesWhy Modern Thyroid Clinic prioritizes listening, full panels, and patient empowermentJessica’s favorite part of the work: celebrating symptom improvement and life restorationJessica’s view: thyroid issues are not a life sentence when treated appropriatelyKrystal’s early foundation in prevention-focused care and integrative medicineHow Krystal’s friend’s thyroid storm and Graves disease helped pull her deeper into thyroid workWhy hormones and thyroid must be addressed together, especially in midlifeKrystal’s experience diagnosing Hashimoto’s in patients who were never told they had it, even after decadesCommon misunderstandings: antibodies matter, T3 can be life-changing, lifestyle can amplify resultsA striking example: a patient’s TSH dropping from around 100 to under 1 with treatment and labs normalizing quicklyBehind-the-scenes fun: Hawaii, a huge family, and the military dolphin trainer story In This Episode, You Will Learn Why many thyroid patients still struggle when care focuses only on TSHHow thyroid symptoms can be real even when labs appear “normal” on limited testingWhy full thyroid panels and antibody tracking can change clinical decisions and outcomesHow gaslighting and obesity bias show up in real healthcare settingsWhy thyroid and hormones often need to be treated together for best resultsWhat “no one size fits all” really means in thyroid medication and dosingWhy treating symptoms alongside labs can restore quality of lifeHow thyroid support can become the foundation that makes lifestyle change possibleWhy patients deserve to feel well in every season of life, including perimenopause and menopauseHow Modern Thyroid Clinic approaches education, empowerment, and individualized care Featured Clinicians Brandy Valentino, RN, WHNP, CNM Brandy shares her path from labor and delivery and midwifery into thyroid care, including how questioning cookie-cutter algorithms led her to a more personalized, patient-centered approach. Jessica Strauss, DNP, FNP-C Jessica explains how her own symptoms and years of being dismissed shaped her approach to care, and why she is passionate about full thyroid evaluation, belief in patient symptoms, and restoring hope. Krystal Adams, MSN, FNP-BC, LSO Krystal describes her prevention-focused background, her love of hormone care, and how combining hormone and thyroid optimization can help patients finally feel normal again. 📲 Follow McCall McPherson & Modern Thyroid and Wellness 💻 Website: modernthyroidclinic.com 🐦 X / Twitter: @thyroidexpert 🌐 Host Website: mccallmcpherson.com 📺 YouTube: McCall McPherson Channel 📘 Facebook: McCall McPherson PAC 📸 Instagram: @mccallmcphersonpa

    1hr 4min
  8. 69: GLP-1s Are Not Just for Weight Loss - The Smarter Microdosing Strategy for Metabolism Muscle and Long Term Health with McCall McPherson

    12 FEB

    69: GLP-1s Are Not Just for Weight Loss - The Smarter Microdosing Strategy for Metabolism Muscle and Long Term Health with McCall McPherson

    What if GLP-1 medications work best not at higher doses, but with slower, personalized microdosing? In this solo Ask Me Anything episode of Modern Thyroid and Wellness, McCall McPherson answers your most pressing questions about GLP-1 medications. Drawing from clinical experience and current research, she breaks down how these medications actually work, why microdosing matters, and how to minimize side effects while protecting metabolism, muscle, and long-term health. McCall explores the connection between GLP-1s and inflammation, thyroid function, fertility, cancer risk, longevity, and metabolic recovery. She also explains when patients may need long-term therapy, how to successfully come off these medications, and why slow, personalized dosing produces the safest and most sustainable results. If you’ve heard conflicting information about GLP-1s, this episode offers clarity, context, and a clinically grounded perspective on how to use them wisely. Key Topics Covered What GLP-1 medications are and how they work beyond appetite suppressionWhy microdosing leads to better outcomes and fewer side effectsThe real cause of most GLP-1 side effects: rapid weight loss and under-fuelingSemaglutide vs. tirzepatide and how to choose the right optionWhy most patients do not need to stay on GLP-1s foreverHow improving insulin sensitivity and leptin resistance supports long-term weight maintenanceWhen long-term GLP-1 use may be appropriate, especially for chronic inflammationStrategies for tapering off successfully, including slow dose reduction and metabolic supportThe relationship between GLP-1s and thyroid function, Hashimoto’s antibodies, and medication adjustmentsPregnancy, fertility, and breastfeeding recommendationsWhy weight loss timelines vary based on thyroid health and metabolic statusThe role of treatment breaks in maintaining medication effectiveness GLP-1 Benefits You May Not Know About Powerful anti-inflammatory effects through multiple biological pathwaysReduced risk of several cancers, including breast, lung, colorectal, and pancreaticLower risk of major cardiovascular events such as heart attack and strokeReduced all-cause mortality by approximately 15–20%Improvements in metabolic health, blood sugar control, and insulin sensitivityPotential benefits for compulsive behaviors, cravings, and addiction patterns Common Concerns Addressed Hair loss and muscle loss Usually caused by rapid weight loss or inadequate protein and nutrient intake, not the medication itself. Thyroid cancer risk Human studies have not shown an increased risk for common thyroid cancers. GLP-1s should be avoided only in patients with a history of medullary thyroid carcinoma or MEN syndromes. Thyroid medication changes Weight loss and metabolic shifts often require dose adjustments over time. Lifestyle Strategies That Support Success Prioritize strength training to preserve muscle and metabolic rateFocus on adequate protein and micronutrient intakeAvoid aggressive calorie restrictionIncorporate walking and low-stress movementAddress thyroid optimization and metabolic health before expecting rapid results 📲 Follow McCall McPherson & Modern Thyroid and Wellness 💻 Website: modernthyroidclinic.com 🐦 X / Twitter: @thyroidexpert 🌐 Host Website: mccallmcpherson.com 📺 YouTube: McCall McPherson Channel 📘 Facebook: McCall McPherson PAC 📸 Instagram: @mccallmcphersonpa

    30 min

About

Unlock the latest insights into thyroid health and wellness with McCall McPherson, PA-C. Through expert interviews, personal stories, and actionable advice, this podcast dives deep into thyroid disorders, exploring how they impact everything from energy levels to mental clarity. Whether you're navigating your own thyroid journey or seeking cutting-edge solutions for optimal health, you'll find practical tips and holistic strategies to support your well-being. Join McCall as she empowers listeners to take control of their thyroid health and live a more vibrant life.

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