Empowered Patient Podcast

Karen Jagoda

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.

  1. 16H AGO · BONUS

    Precision Medicine Platform Targets Specific Brain Region to Treat PTSD with Dr. Jenifer Perusini Neurovation Labs TRANSCRIPT

    Dr. Jennifer Perusini, CEO and Founder of Neurovation Labs, is developing a precision medicine platform to create targeted therapeutics and diagnostic tools that treat specific brain regions to address central nervous system diseases. For the treatment of PTSD, the approach focuses on the overactive amygdala due to dysregulated glutamate signaling. This objective, brain-based approach of treating a discrete part of the brain rather than the whole brain moves mental health treatment beyond the current one-size-fits-all approach, reducing side effects and improving outcomes. Jennifer explains, "What we are doing is really taking an objective, precision approach to treating mental health disorders, something like an oncology model. So what we really care about is that mental health disorders and psychiatric disorders are rooted in brain dysfunction, yes, but critically that dysfunction occurs in very discreet brain regions and circuits, not necessarily uniformly across the entire brain. So we have really developed a platform designed to identify compounds with dual potential. Precision therapeutics that act on specific brain regions, as well as diagnostic imaging agents that can reveal receptor-level dysfunction and circuit activity in the brain. And so our lead asset and main indication right now is for PTSD, post-traumatic stress disorder." "I think that academics like to focus on this research in very specific brain regions, but that therapeutic angle really hasn't caught up yet. And so, really more specifically, what we're doing is focusing on a very particular signal, an excitatory neurotransmitter in the brain called glutamate, which is a key regulator of neural activity and cell firing. And so there are many disorders, including PTSD, that are affected by dysregulated glutamate signaling. However, the glutamate drugs that are on the market today really bind to the whole brain. So that's just something that hasn't caught up yet, and that's what we're trying to do." #NeurovationLabs #PrecisionMedicine #PTSD #Neuroscience #MentalHealthInnovation #Biomarkers #DrugDiscovery #Glutamate #BrainHealth #DigitalHealth #HealthTech NeurovationLabs.com Listen to the podcast here

  2. 16H AGO

    Precision Medicine Platform Targets Specific Brain Region to Treat PTSD with Dr. Jenifer Perusini Neurovation Labs

    Dr. Jennifer Perusini, CEO and Founder of Neurovation Labs, is developing a precision medicine platform to create targeted therapeutics and diagnostic tools that treat specific brain regions to address central nervous system diseases. For the treatment of PTSD, the approach focuses on the overactive amygdala due to dysregulated glutamate signaling. This objective, brain-based approach of treating a discrete part of the brain rather than the whole brain moves mental health treatment beyond the current one-size-fits-all approach, reducing side effects and improving outcomes. Jennifer explains, "What we are doing is really taking an objective, precision approach to treating mental health disorders, something like an oncology model. So what we really care about is that mental health disorders and psychiatric disorders are rooted in brain dysfunction, yes, but critically that dysfunction occurs in very discreet brain regions and circuits, not necessarily uniformly across the entire brain. So we have really developed a platform designed to identify compounds with dual potential. Precision therapeutics that act on specific brain regions, as well as diagnostic imaging agents that can reveal receptor-level dysfunction and circuit activity in the brain. And so our lead asset and main indication right now is for PTSD, post-traumatic stress disorder." "I think that academics like to focus on this research in very specific brain regions, but that therapeutic angle really hasn't caught up yet. And so, really more specifically, what we're doing is focusing on a very particular signal, an excitatory neurotransmitter in the brain called glutamate, which is a key regulator of neural activity and cell firing. And so there are many disorders, including PTSD, that are affected by dysregulated glutamate signaling. However, the glutamate drugs that are on the market today really bind to the whole brain. So that's just something that hasn't caught up yet, and that's what we're trying to do." #NeurovationLabs #PrecisionMedicine #PTSD #Neuroscience #MentalHealthInnovation #Biomarkers #DrugDiscovery #Glutamate #BrainHealth #DigitalHealth #HealthTech NeurovationLabs.com Download the transcript here

    17 min
  3. 18H AGO · BONUS

    About Me Initiative Supports Stronger Connections Between Patients and Hospital Care Teams with Dr. Paul Testa and Dr. Katherine Hochman NYU Langone Health TRANSCRIPT

    Dr. Paul Testa, Chief Health Informatics Officer who helped create the About Me Initiative at NYU Langone Health, and Dr. Katherine Hochman, Director of Hospital Medicine at NYU Langone Health, who envisioned the initiative, discuss the benefits of encouraging patients to provide non-medical information. The goal is to help care teams see patients as whole people beyond their diagnoses and to give patients an opportunity to share interests, hobbies, and fun facts that can help build trust and meaningful human connections. This About Me Initiative is being expanded from inpatient care to outpatient settings, such as infusion centers. Paul explains, "The About Me section in our EHR Epic is something that NYU Langone developed with the inspiration of Dr. Hochman, and it's essentially a dedicated discreet space in the medical record to allow patients to declare themselves, allowing them to give them a space that is transparent to all the users of the electronic health record, which are many and vast in their rules. So let them articulate something beyond their disease process or their health. So often, we reduce records to pneumonia, a broken hip, or an infection. The patient is so much more than that, and patients want to share that with us. We know that from practicing for years, Kathy and I both know that the way you connect with patients is through a narrative. Our currency is narrative. This is a location where either a patient or, if they choose to defer, can have one of their nurses or care team members provide a small sample of who they are outside of the care environment."   Katherine elaborates, "So I'm a hospitalist. Every Tuesday, I come into 16 to 18 new patients. And at NYU Langone, our length of stay keeps getting shorter and shorter, which is fantastic for patients because we want to get them in and out of the hospital as quickly and as safely as possible. But by definition, if patients stay shorter and shorter, we don't have as much time to connect. So the About Me Initiative really kicks off that connection that Paul was talking about a second ago. So long ago, and this is how it started, I would tell my teams, slow down to speed up, get to know who this patient is before getting into the heart failure, the pneumonia, the COPD, and really try to establish a little bit of a connection and build trust." #NYULangone #PatientVoices #PatientCare #HealthcareInnovation #PatientExperience #HealthIT #EHR #EpicEHR #HumanConnection #HealthcareTransformation #PatientCentered #MedicalTechnology #DigitalHealth #EmpathyInMedicine  nyulangone.org  Listen to the podcast here

  4. 18H AGO

    About Me Initiative Supports Stronger Connections Between Patients and Hospital Care Teams with Dr. Paul Testa and Dr. Katherine Hochman NYU Langone Health

    Dr. Paul Testa, Chief Health Informatics Officer who helped create the About Me Initiative at NYU Langone Health, and Dr. Katherine Hochman, Director of Hospital Medicine at NYU Langone Health, who envisioned the initiative, discuss the benefits of encouraging patients to provide non-medical information. The goal is to help care teams see patients as whole people beyond their diagnoses and to give patients an opportunity to share interests, hobbies, and fun facts that can help build trust and meaningful human connections. This About Me Initiative is being expanded from inpatient care to outpatient settings, such as infusion centers. Paul explains, "The About Me section in our EHR Epic is something that NYU Langone developed with the inspiration of Dr. Hochman, and it's essentially a dedicated discreet space in the medical record to allow patients to declare themselves, allowing them to give them a space that is transparent to all the users of the electronic health record, which are many and vast in their rules. So let them articulate something beyond their disease process or their health. So often, we reduce records to pneumonia, a broken hip, or an infection. The patient is so much more than that, and patients want to share that with us. We know that from practicing for years, Kathy and I both know that the way you connect with patients is through a narrative. Our currency is narrative. This is a location where either a patient or, if they choose to defer, can have one of their nurses or care team members provide a small sample of who they are outside of the care environment."   Katherine elaborates, "So I'm a hospitalist. Every Tuesday, I come into 16 to 18 new patients. And at NYU Langone, our length of stay keeps getting shorter and shorter, which is fantastic for patients because we want to get them in and out of the hospital as quickly and as safely as possible. But by definition, if patients stay shorter and shorter, we don't have as much time to connect. So the About Me Initiative really kicks off that connection that Paul was talking about a second ago. So long ago, and this is how it started, I would tell my teams, slow down to speed up, get to know who this patient is before getting into the heart failure, the pneumonia, the COPD, and really try to establish a little bit of a connection and build trust." #NYULangone #PatientVoices #PatientCare #HealthcareInnovation #PatientExperience #HealthIT #EHR #EpicEHR #HumanConnection #HealthcareTransformation #PatientCentered #MedicalTechnology #DigitalHealth #EmpathyInMedicine  nyulangone.org Download the transcript here

    23 min
  5. 1D AGO · BONUS

    Real-Time Clinical Artificial Intelligence Drives Precision Care with Dr. David Kirk Regard TRANSCRIPT

    Dr. David Kirk, Chief Medical Officer at Regard, discusses the role and benefits of real-time clinical AI to help clinicians navigate patient charts and find critical information to prevent medication management errors and misdiagnoses. The Regard platform can also generate proactive documentation, allowing physicians to complete their documentation more accurately and efficiently, reducing note-bloat and the need for after-hours charting. One key goal of using AI is to free physicians to spend more time on the art of medicine, directly working with patients.   David explains, "So, Regard with real-time clinical artificial intelligence software, is helping clinicians propose the right diagnosis and information while they're working in the chart. Our mission is to make patient care as clear as possible. At the same time, we make sure that the doctors are getting the support they need so they can better support the patient. The charts of patients are getting bigger and bigger every year because more and more data is going into the charts. And as that happens, the really important thing that we as physicians need to find is diluted." "Some research even suggests that maybe doctors are going to see 3% of the data that comes in in the chart when a patient comes into the hospital. As the physician, I'm trying to understand a patient's clinical story with only having access to three pages. Our goal is for artificial intelligence to find important information in that deep sea of data so the treatment team can make better decisions. Maybe you can correct the documentation. What that means is the physician is doing all the work in their natural workflow. We're not having to do prep work during downtime at home, and we're not trying to wrap up notes at night. We need the documentation to be done proactively in a way that is as accurate as possible for the patient at the time of care." #Regard #HealthcareAI #DigitalHealth #MedicalTechnology #PatientCare #HealthTech #AIinMedicine #ClinicalDocumentation #HealthcareInnovation #MedicalAI #PhysicianSupport Regard.com Listen to the podcast here

  6. 1D AGO

    Real-Time Clinical Artificial Intelligence Drives Precision Care with Dr. David Kirk Regard

    Dr. David Kirk, Chief Medical Officer at Regard, discusses the role and benefits of real-time clinical AI to help clinicians navigate patient charts and find critical information to prevent medication management errors and misdiagnoses. The Regard platform can also generate proactive documentation, allowing physicians to complete their documentation more accurately and efficiently, reducing note-bloat and the need for after-hours charting. One key goal of using AI is to free physicians to spend more time on the art of medicine, directly working with patients.   David explains, "So, Regard with real-time clinical artificial intelligence software, is helping clinicians propose the right diagnosis and information while they're working in the chart. Our mission is to make patient care as clear as possible. At the same time, we make sure that the doctors are getting the support they need so they can better support the patient. The charts of patients are getting bigger and bigger every year because more and more data is going into the charts. And as that happens, the really important thing that we as physicians need to find is diluted." "Some research even suggests that maybe doctors are going to see 3% of the data that comes in in the chart when a patient comes into the hospital. As the physician, I'm trying to understand a patient's clinical story with only having access to three pages. Our goal is for artificial intelligence to find important information in that deep sea of data so the treatment team can make better decisions. Maybe you can correct the documentation. What that means is the physician is doing all the work in their natural workflow. We're not having to do prep work during downtime at home, and we're not trying to wrap up notes at night. We need the documentation to be done proactively in a way that is as accurate as possible for the patient at the time of care." #Regard #HealthcareAI #DigitalHealth #MedicalTechnology #PatientCare #HealthTech #AIinMedicine #ClinicalDocumentation #HealthcareInnovation #MedicalAI #PhysicianSupport Regard.com Download the transcript here

    20 min
  7. 2D AGO · BONUS

    Data Analytics Platform Improves Patient Safety and Hospital Performance with Daniel Hart Sentact TRANSCRIPT

    Daniel Hart, CEO of Sentact, describes the need to integrate technology, analytics, and services for hospitals and health systems to improve patient safety, patient outcomes, and regulatory readiness. One of Sentact's key goals is to help organizations gain insights from data to allow them to move from a reactive posture using lagging indicators to a proactive environment supported by AI and real-time data to generate early warning signals. Successful implementation of these insights also reduces operational costs and potentially eases clinician burnout. Daniel explains, "Sentact is a healthcare technology, services, and analytics company. Three core pillars of our business are across tech analytics and services. We serve the hospital and health system market primarily, although we do have all types of healthcare organizations in our customer base. But as an example, a representative example, we service 60% of the top 20 health systems in the market with our solutions. And we are focused on patient safety, quality, experience, and regulatory readiness or compliance. That's the corner of healthcare in which we play."  "We offer a range of services through the combination of several companies over the last 12 to 18 months. And we're really excited about the integrated platform that we have compiled. And that platform extends from the credentialing function at a hospital to comprehensive rounding to support safety experience and compliance initiatives. It also includes clinical analytics to help manage provider performance and patient safety, to provide the necessary protections of safety information, and promote continuous learning." #Sentact #HealthcareQuality #HealthcareTechnology #PatientSafety #HealthcareInnovation #DigitalHealth #HealthIT #PatientExperience #PatientOutcomes #HealthcareAnalytics #ClinicalOperations #RegulatoryCompliance #HealthSystemManagement #RiskManagement #QualityOutcomes Sentact.com  Listen to the podcast here

  8. 2D AGO

    Data Analytics Platform Improves Patient Safety and Hospital Performance with Daniel Hart Sentact

    Daniel Hart, CEO of Sentact, describes the need to integrate technology, analytics, and services for hospitals and health systems to improve patient safety, patient outcomes, and regulatory readiness. One of Sentact's key goals is to help organizations gain insights from data to allow them to move from a reactive posture using lagging indicators to a proactive environment supported by AI and real-time data to generate early warning signals. Successful implementation of these insights also reduces operational costs and potentially eases clinician burnout. Daniel explains, "Sentact is a healthcare technology, services, and analytics company. Three core pillars of our business are across tech analytics and services. We serve the hospital and health system market primarily, although we do have all types of healthcare organizations in our customer base. But as an example, a representative example, we service 60% of the top 20 health systems in the market with our solutions. And we are focused on patient safety, quality, experience, and regulatory readiness or compliance. That's the corner of healthcare in which we play."  "We offer a range of services through the combination of several companies over the last 12 to 18 months. And we're really excited about the integrated platform that we have compiled. And that platform extends from the credentialing function at a hospital to comprehensive rounding to support safety experience and compliance initiatives. It also includes clinical analytics to help manage provider performance and patient safety, to provide the necessary protections of safety information, and promote continuous learning." #Sentact #HealthcareQuality #HealthcareTechnology #PatientSafety #HealthcareInnovation #DigitalHealth #HealthIT #PatientExperience #PatientOutcomes #HealthcareAnalytics #ClinicalOperations #RegulatoryCompliance #HealthSystemManagement #RiskManagement #QualityOutcomes Sentact.com  Download the transcript here

    21 min
4.9
out of 5
18 Ratings

About

Empowered Patient Podcast with Karen Jagoda is a window into the latest innovations in digital health, the changing dynamic between doctors and patients, and the emergence of precision medicine. The show covers such topics as aging in place, innovative uses for wearables and sensors, advances in clinical research, applied genetics, drug development, and challenges for connected health entrepreneurs.