As the Podcast's description says, the main theme for discussion in the show are the ins and outs of Magic Online. Conor, Dave and Nathaniel discuss every week what they wish for in future MTGO improvements, how things currently work, and the community of Magic Online.
What I like the best about the podcast is the sincerity and the debate between the hosts. They all come from different backgrounds and have different relationships with the program, so they don't always agree with each other, but this paves the way for good discussions about the game.
Nevertheless, it's clear that the three of them love MTG and MTGO and only wish for it to be better. That's what makes the show enjoyable.