TopMedTalk

TopMedTalk

TopMedTalk for the latest medical news surrounding Anaesthesia, Perioperative Care and Enhanced Recovery. Live updates from conferences; Journal Club; Techno Talk and Hot-Topic podcasts. Continuing Medical Education (CME) on the go

  1. 1d ago

    Hemodynamic Therapy at EBPOM: Using the Peripheral Perfusion Index Beyond Blood Pressure

    At the Evidence-Based Perioperative Medicine (EBPOM) World Congress in London, Andy Cumpstey interviews Mike Grocott, Professor of Anaesthesia and Critical Care Medicine at the University of Southampton and consultant in critical care medicine at University Hospital Southampton NHS Foundation Trust and Nikolai Bang-Foss, Professor, Chair in Acute Perioperative Medicine and Pathophysiology at the University of Copenhagen and Consultant & Head of Department of gastrointestinal and orthopaedic anaesthesia at Copenhagen University Hospital The discussion comes after a hemodynamic therapy debate on fluid and blood pressure management. Grocott argues that while clinicians aim to optimize circulating volume, tissue perfusion, and avoid fluid overload, current monitoring makes these goals difficult and evidence for goal-directed fluid/hemodynamic therapy is mixed; low flow/pressure is harmful but raising them doesn't reliably improve outcomes. Foss emphasizes that vasoconstrictors can normalize blood pressure without improving flow or organ perfusion and that preload responsiveness is not a marker of hypovolemia because it can reflect vasoplegia. He proposes using the peripheral perfusion index (PI) from standard pulse oximeter plethysmography as a real-time surrogate of perfusion, citing associations between low PI (e.g., 1.5, especially 0.5) and increased mortality and acute kidney injury, and describes clinical examples where small fluid boluses increased PI despite stable blood pressure and stroke volume.

  2. Nov 5

    ANESTHESIOLOGY® 2026: Target Controlled Infusion (TCI) - Models, Practice and Sustainability

    ANESTHESIOLOGY® 2026, in San Diego, TopMedTalk hosts Kate Leslie and Andy Cumpstey speak with Dr Damon Kamming, Clinical Instructor within the Stanford University Department of Anesthesiology, Perioperative, and Pain Medicine and Michel Struys, Professor of Anesthesiology and Clinical Pharmacology at the University of Groningen and the University Medical Center Groningen (UMCG) about target-controlled infusion (TCI) for intravenous anesthesia. They explain how TCI uses pharmacokinetic/pharmacodynamic models and patient covariates beyond weight (age, sex, height, fat-free mass) to target and maintain drug concentrations, commonly for propofol and opioids, reducing clinician pump adjustments and drug accumulation when paired with effect monitoring (e.g., EEG) and cardiovascular signs. They discuss newer broad models such as Eleveld, limits at extremes of body size, and practical safety issues like dedicated IV access. Kamming links wider TIVA/TCI adoption to improved recovery and lower global warming potential versus volatile agents, citing UCLH's shift toward more TIVA, use of 2% propofol to reduce plastic waste, and desflurane reduction. The group notes TCI is not yet available in the US, attributing this mainly to the need for a company to invest in FDA submission and adoption efforts within departments. LISTEN TO THE PODCAST MENTION ABOUT OPIOIDS HERE: https://topmedtalk.libsyn.com/anesthesiology-2026-opioid-overdose-prevention-and-treatment

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TopMedTalk for the latest medical news surrounding Anaesthesia, Perioperative Care and Enhanced Recovery. Live updates from conferences; Journal Club; Techno Talk and Hot-Topic podcasts. Continuing Medical Education (CME) on the go

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