The PennHealthX Podcast

PennHealthX

The Penn HealthX Podcast focuses on the intersection of medicine and business, with an emphasis on healthcare management, entrepreneurship, and technology (H-MET). This podcast has two aims. First, we want to highlight excellent work happening at The University of Pennsylvania, in Philadelphia, and beyond. Second, we want to help students and those early in their medical careers understand how to become leaders in the field, and use their skills outside of strictly clinical medicine. We intend to achieve these goals by interviewing students and faculty members who are working in the H-MET space. We also plan to discuss current events, trends and opportunities in healthcare, and other topics future healthcare leaders need to know about. Penn Health-X is supported by our generous donors - Dr. Wong. Dr. Slevin, Dr. Anand, and Dr. Wills. Find us on iTunes! https://itunes.apple.com/us/podcast/the-penn-healthx-podcast/id1271378904?mt=2

  1. May 20

    90 - Building the Doctor's Second Brain - Dr. Dereck Paul

    Dr. Dereck Paul, MD, is the co-founder and CEO of Glass Health, an AI platform helping clinicians with clinical decision-making, documentation, and workflow optimization. Dr. Paul’s path into healthcare innovation began long before residency — from studying music composition to applying to Y Combinator before even starting medical school. In this episode, Dr. Paul reflects on the pivotal decisions that shaped his career, including balancing startup ambitions with clinical training and ultimately taking leave from residency to scale Glass Health. He shares how his frustrations with outdated healthcare software inspired him to build tools designed specifically around the realities of clinical practice and explains how modern AI systems can function as real-time collaborators for physicians. We also explore the rapidly evolving intersection of AI and medicine, including how clinicians and students can prepare for a future increasingly shaped by large language models and automation. Dr. Paul discusses why resisting AI is the wrong approach, how physicians can stay on the technological frontier, and why empathy and firsthand clinical experience remain critical when building healthcare technology. The conversation closes with advice for students and trainees considering entrepreneurship: embrace uncertainty, recognize rare technological inflection points when they arise, and pursue the work that would leave you with the fewest regrets.

    90 - Building the Doctor's Second Brain - Dr. Dereck Paul
  2. 11/14/2025

    86 - Dr. Akl Fahed - Digital Health, Genetics, & GLP-1s

    In this episode of the PennHealthX Podcast, Habib sits down with Dr. Akl Fahed to discuss his career as an interventional cardiologist, physician–scientist, and digital health entrepreneur working at the frontiers of genomic medicine and chronic disease care. Dr. Fahed serves at Massachusetts General Hospital and the Broad Institute, where he leads an NIH-funded research program focused on using large-scale genomics and data science to better understand cardiometabolic disease and identify risk long before symptoms appear. He is also the clinical co-founder of GoodPath, a virtual-first care platform that delivers integrated, whole-person management for chronic conditions through a multidisciplinary, value-based model. This episode explores how advances in genetics, data-driven prevention, and technologies like AI can transform the way we identify, manage, and ultimately prevent chronic illness. We discuss the emergence of obesity “endotypes,” the promise of polygenic risk scores, and the rapidly expanding role of GLP-1 medications. Dr. Fahed also shares how digital health tools can reduce fragmentation, enhance patient engagement, and address rising healthcare costs by meeting patients where they are. His career offers a compelling look at how clinicians can shape the future of medicine by bridging scientific discovery, clinical practice, and technology to build systems that meaningfully improve patient health.

    86 - Dr. Akl Fahed - Digital Health, Genetics, & GLP-1s
4.9
out of 5
67 Ratings

About

The Penn HealthX Podcast focuses on the intersection of medicine and business, with an emphasis on healthcare management, entrepreneurship, and technology (H-MET). This podcast has two aims. First, we want to highlight excellent work happening at The University of Pennsylvania, in Philadelphia, and beyond. Second, we want to help students and those early in their medical careers understand how to become leaders in the field, and use their skills outside of strictly clinical medicine. We intend to achieve these goals by interviewing students and faculty members who are working in the H-MET space. We also plan to discuss current events, trends and opportunities in healthcare, and other topics future healthcare leaders need to know about. Penn Health-X is supported by our generous donors - Dr. Wong. Dr. Slevin, Dr. Anand, and Dr. Wills. Find us on iTunes! https://itunes.apple.com/us/podcast/the-penn-healthx-podcast/id1271378904?mt=2