PodcastDX

PodcastDX

PodcastDX is an interview based weekly series. Guests share experience based medical insight for our global audience. We have found that many people are looking for a platform, a way to share their voice and the story that their health journey has created. Each one is unique since even with the same diagnosis, symptoms and the way each person will react to a diagnosis, is different. Sharing what they have experienced and overcome is a powerful way our guests can teach others with similar ailments. Many of our guests are engaging in self-advocacy while navigating a health condition, many are complex and without a road-map to guide them along their journey they have developed their own. Sharing stories may help others avoid delays in diagnosis or treatment or just give hope to others that are listening. Sharing is empowering and has a healing quality of its own. Our podcast provides tips, hints, and support for common healthcare conditions. Our guests and our listeners are just like you- navigating the complex medical world. We hope to ease some tension we all face when confronted with a new diagnosis. We encourage anyone wanting to share their story with our listeners to email us at info@PodcastDX.com ​

  1. 4D AGO

    The Gut Brain Revolution: Why One System Can't Be Treated Alone

    The gut–brain revolution is about treating the digestive system and the nervous system as one integrated network instead of two separate organs that happen to share a body. The gut–brain axis is a bidirectional communication system: the brain influences digestion, motility, and gut sensation, while the gut and its microbiota send chemical, neural, and immune signals back to the brain that can shape mood, cognition, and even neurodegeneration. Central to this loop is the vagus nerve, the longest cranial nerve, which carries most of the traffic from gut to brain and modulates inflammation, intestinal permeability, and autonomic balance. When one side of this axis is struggling—chronic stress, trauma, infection, dysbiosis, "leaky gut," or ongoing inflammation—the other side often shows up with symptoms like anxiety, depression, brain fog, or functional GI disorders.​ Because of this, "treating the brain" without addressing gut health, or "treating the gut" without considering mental health and stress physiology, often means chasing symptoms instead of root causes. Emerging evidence supports combined care plans that may blend nutrition changes, targeted probiotics, and anti‑inflammatory strategies with cognitive behavioral therapy, mindfulness, and stress‑reduction techniques to calm both the GI tract and the nervous system. Interventions that support vagal tone—such as paced breathing, certain forms of meditation, and gentle movement—may further help regulate this axis by improving autonomic balance and reducing inflammatory signaling between gut and brain. For patients and clinicians, the key message is that persistent "brain" symptoms might start in the gut, and chronic "gut" symptoms may be maintained by the brain, making integrated, two‑system treatment not a trend but a clinical necessity.

    22 min
  2. FEB 10

    Promising New Cancer Screening Methods

    Promising new cancer screening methods are pivoting toward multi-cancer early detection (MCED) blood tests (liquid biopsies) and AI-enhanced imaging, which aim to detect multiple cancer types from a single, non-invasive sample, often before symptoms arise. These technologies, including the Galleri test and Novelna's protein-based tests, analyze DNA, proteins, or methylation patterns to identify cancer signals.  Multi-Cancer Early Detection (MCED) Blood Tests: These tests, often called liquid biopsies, detect DNA or proteins shed by cancer cells into the bloodstream, identifying early-stage cancers (e.g., ovarian, pancreatic) that lack standard screening protocols. Galleri Test: Analyzes chemical methylation patterns to detect over 50 types of cancer, with the potential to indicate the cancer's origin in the body. Novelna's Test: An experimental test analyzing protein signatures, showing high accuracy in identifying 18 early-stage cancers, including 93% of stage 1 cancers in men. TriOx Test: A new, Oxford-developed test showing high sensitivity in detecting trace cancer DNA. AI and Machine Learning in Screening: AI is enhancing existing imaging techniques (e.g., mammography) to improve accuracy and efficiency in reading scans, reducing false positives. Other Liquid Biopsies: Research into analyzing blood, breath, and urine for early signs of cancer, offering a less invasive alternative to tissue biopsies.  While offering immense promise for reducing cancer mortality, many of these technologies, including MCED, are still in research or early implementation phases, and they can produce false positives.

    20 min
  3. FEB 3

    Chronic Illness Isn't Rare Anymore: Why The System Is Trying To Catch-up

    Chronic illness is now the norm, not the exception, and our healthcare system is scrambling to keep up. ​In this episode, "Chronic Illness Isn't Rare Anymore: Why The System Is Trying To Catch Up," we dig into why so many adults are living with at least one chronic condition, how the current system was built for short-term, acute care, and what that mismatch means for people trying to manage complex, lifelong diagnoses. We talk about the hidden costs of navigating appointments, medications, insurance, and burnout, and explore what needs to change—from prevention and policy to care teams and patient advocacy—to actually support those living with chronic illness today. ​Chronic illness is no longer a rare, edge-case scenario; it is now a majority experience in the United States, with approximately 76% of adults living with at least one chronic condition. As of 2025, over half of U.S. adults suffer from two or more, making these conditions the primary driver of the nation's $4.5 trillion healthcare spending.  ​The healthcare system is rushing to "catch up" because the traditional model—designed for acute, short-term care—is failing to handle the, persistent, long-term, and complex needs of a majority-chronically-ill population.  ​The New Reality: Why Chronic Illness is Everywhere ​Chronic diseases like heart disease, diabetes, obesity, and autoimmune disorders have reached epidemic levels due to a combination of factors, according to the Centers for Disease Control and Prevention (CDC) and other experts:  Aging Population: The number of Americans over 65 is growing rapidly, with over 58 million in this group, expected to increase significantly. Lifestyle & Environment: Poor nutrition, physical inactivity, tobacco use, and excessive alcohol consumption are driving the increase. Systemic Factors: Environmental exposures to toxins, chemicals in food, and stress from modern living contribute to high prevalence. Rising Youth Rates: The prevalence of conditions like obesity and depression has increased among young adults.  ​​ Why the System is "Catching Up" ​The system is undergoing a massive shift from "reactive" to "proactive" care, driven by necessity rather than choice.  The Financial Crisis: Chronic disease management accounts for nearly 90% of U.S. healthcare spending. If left unchecked, these costs could drive the healthcare system to collapse, making cost reduction for chronic conditions a top priority for 2025. Ineffectiveness of Old Models: The "fee-for-service" model, which pays for volume, is being replaced by "value-based" care, focusing on results and preventing readmissions. Integration of Technology: To manage the scale, the system is leveraging artificial intelligence (AI), telehealth, and remote monitoring to keep patients with chronic conditions at home and out of the hospital. Focus on Root Causes: There is a move away from just managing symptoms to addressing root causes, such as nutrition, social determinants of health (housing, income), and reducing systemic inflammation.  ​Key Changes in the "Catching Up" Process ​Redesigning Care: Moving toward "patient-centered" care, which focuses on empowering individuals to manage their own illnesses and providing more comprehensive support, rather than just treating symptoms as they appear. Addressing Social Determinants: Recognizing that where people live, work, and age impacts their health, systems are expanding beyond the clinic to address food insecurity and safe spaces for exercise. Preventive & Early Care: Increased focus on intervening early, especially in underserved, low-income, and marginalized communities that bear a disproportionate burden of disease. Workplace Wellness: Companies are investing in preventative care, such as on-site health assessments and mental health support, to reduce the impact of chronic illness on productivity.  ​The shift from acute to chronic disease as the leading cause of death is forcing a comprehensive reinvention of the US health system.

    9 min
  4. JAN 27

    From Survival to Quality of Life: Why Outcomes are Being Redefined

    FROM SURVIVAL TO QUALITY OF LIFE: WHY OUTCOMES ARE BEING REDEFINED THE FUNDAMENTAL SHIFT IN MEDICINE For decades, medicine measured success through a singular lens: survival. Did the patient live? Did the procedure work? While these metrics remain important, healthcare is undergoing a profound transformation that redefines what "winning" actually means[1]. The new standard is no longer just extending life—it's enabling patients to live purposefully, functionally, and with dignity[2]. This shift reflects a critical insight: surviving is not the same as living well. WHY OUTCOMES ARE BEING REDEFINED Beyond Binary Success Traditional outcome metrics operated in black-and-white terms. A femur repair was "successful" if the fracture healed—regardless of whether the patient could walk without pain, climb stairs, or return to work[3]. Today, healthcare systems recognize this approach as incomplete and outdated. Patient-Reported Outcomes Measures (PROMs) The healthcare industry is now systematically integrating patient voices into outcome measurement. These tools capture what patients actually experience: physical functioning, emotional well-being, social participation, and overall quality of life[4]. The Centers for Medicare & Medicaid Services (CMS) has formally incorporated patient-reported outcome measures into quality reporting frameworks, signaling a structural shift in how healthcare success is defined[5]. The Quintuple Aim Modern healthcare reform is reframing success across five dimensions[6]: ·      Patient Experience: Tailored treatments based on individual data and preferences ·      Population Health: Proactive, preventative care delivery ·      Cost Reduction: Connecting patients to appropriate care and reducing avoidable hospitalizations ·      Provider Well-Being: Extending clinical reach through technology and team-based care ·      Equitable Care: Ensuring access regardless of geography or circumstance WHAT THIS MEANS IN PRACTICE Real-World Impact Advanced remote patient monitoring programs demonstrate the difference this redefinition makes. One program achieved a 230% increase in guideline-directed medical therapy for heart failure patients, adding an average of 5 years to their lives—but the metric that matters most is that patients remained home, maintained independence, and preserved quality of life while achieving better clinical outcomes[7]. Shared Decision-Making Patient preferences now matter. Research shows patients are generally unwilling to accept diminished quality of life simply for extended survival[8]. Healthcare providers increasingly recognize that authentic patient partnership—understanding what matters most to each individual—leads to better adherence, satisfaction, and actual outcomes. THE BOTTOM LINE The redefinition of medical success from "Did you survive?" to "Are you living well?" represents a maturation of healthcare. It acknowledges that modern medicine can often extend life—the question now is how to ensure that extended life is worth living. This shift places patient values, functional abilities, and personal purpose at the center of clinical decision-making. Success in 21st-century medicine means helping patients achieve not just survival, but flourishing. REFERENCES [1] Takeda Oncology. (2025). Living beyond surviving: Patient-centered approach to modern oncology care. Retrieved from https://www.takedaoncology.com/our-stories/living-is-more-than-surviving/ [2] LaBier, D. (2014). Life purpose beyond survival as a metric of quality healthcare. LinkedIn. Retrieved from https://www.linkedin.com/pulse/20140526192226-11896706--life-purpose-beyond-survival-as-a-metric-of-quality-healthcare/ [3] University of South Carolina. (2025). Patient-reported outcome measures essential to clinical decision-making. Retrieved from https://www.sc.edu/uofsc/posts/2025/10/10-patient-centered-quality-measures.php [4] Sermo. (2026). 13 strategies to improve patient care quality in 2026. Retrieved from https://www.sermo.com/resources/13-solutions-for-improving-patient-care-and-outcomes-in-2025/ [5] Medisolv. (2024). Trends in healthcare quality and safety to watch in 2024. Retrieved from https://blog.medisolv.com/articles/healthcare-trends-2024/ [6] Cunningham, E., Chief of Virtual Care and Digital Health, Providence Health. (2024). Cadence outcomes report insights. Cadence Care. Retrieved from https://www.cadence.care/post/cadences-2024-outcomes-report-a-new-era-in-primary-care/ [7] Cadence Care. (2024). Cadence's 2024 outcomes report: A new era in primary care. Retrieved from https://www.cadence.care/post/cadences-2024-outcomes-report-a-new-era-in-primary-care/ [8] PubMed Central. (2008). Patient preferences: Survival vs. quality-of-life considerations. Retrieved from https://pubmed.ncbi.nlm.nih.gov/8410398/

    21 min
  5. JAN 20

    Ai in Medicine Tool Partner or Problem

    *:first-child]:mt-0"> AI in medicine is best understood as a powerful tool and a conditional partner that can enhance care when tightly supervised by clinicians, but it becomes a problem when used as a replacement, deployed without oversight, or embedded in biased and opaque systems. Whether it functions more as a partner or a problem depends on how health systems design, regulate, and integrate it into real clinical workflows.​ Where AI Works Well p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Decision support and diagnosis: AI can read imaging, ECGs, and lab patterns with very high accuracy, helping detect cancers, heart disease, and other conditions earlier and reducing some diagnostic errors.​ p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Workflow and documentation: Tools that draft visit notes, summarize records, and route messages can cut administrative burden and free up clinician time for patients.​ p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Patient monitoring and triage: Algorithms can watch vital signs or wearable data to flag deterioration, triage symptoms online, and guide patients through care pathways, which is especially valuable with clinician shortages.​ Risks and Problems p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Errors, over-reliance, and "automation bias": Studies show clinicians sometimes follow incorrect AI recommendations even when the errors are detectable, which can lead to worse decisions than if AI were not used.​ p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Bias and inequity: If training data underrepresent certain groups, AI can systematically misdiagnose or undertreat them, amplifying existing health disparities.​ p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Trust, explainability, and liability: Black-box systems can undermine shared decision-making when neither doctor nor patient can understand or challenge a recommendation, and they raise hard questions about who is responsible when harm occurs.​ Impact on the Doctor–Patient Relationship p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Potential partner: By handling routine documentation and data crunching, AI can give clinicians more time for conversation, empathy, and shared decisions, supporting more person-centered care.​ p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Potential barrier: If AI outputs dominate visits or generate long lists of differential diagnoses directly to patients, it can increase anxiety, fragment communication, and weaken relational trust.​ How To Keep AI a Partner, Not a Problem p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Keep humans in the loop: Use AI as a second reader or coach, not a final decision-maker; clinicians should retain authority to accept, modify, or reject suggestions.​ p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Demand transparency and evaluation: Health systems should validate tools locally, monitor performance across different populations, and disclose AI use to patients in clear language.​ p]:pt-0 [&>p]:mb-2 [&>p]:my-0"> Align incentives with patient interests: Regulation, reimbursement, and malpractice rules should reward safe, equitable use of AI—not just speed, volume, or commercial uptake.​ In practice, AI in medicine becomes a true partner when it augments human judgment, enhances relationships, and improves outcomes; it becomes a problem when it is opaque, biased, or allowed to replace clinical responsibility.​

    10 min
  6. JAN 13

    Medicine in Transition: Why Healthcare Looks Different tThan a Decade Ago

    Medicine has transitioned due to massive tech adoption (Electronic Health Records EHRs, Artificial Intelligence AI, Telehealth), shifting patient expectations (consumerism, convenience), the rise of value-based care, new treatments (precision medicine), and increased focus on population health and prevention, all while grappling with rising costs, data security, and persistent access/equity gaps, making healthcare more data-driven, personalized, and digitally integrated but also more complex and fragmented.  We try to break it down to try and understand the changes and how they might improve the outcomes when going to the doctor.     Technological Revolution Electronic Health Records (EHRs) & Analytics: Widespread EHR adoption (95% of hospitals by 2017) streamlined data, enabling better analytics for management, diagnosis, and care coordination, notes HNI Healthcare and Becker's Hospital Review. Telehealth & Wearables: Virtual visits, health apps, and fitness trackers (like heart rate monitors) became common, improving access and remote monitoring, says ThriveAP. Artificial Intelligence (AI) & Machine Learning: AI now analyzes complex data for diagnostics, research, and clinical decisions, says Health Tech Academy and National Institutes of Health (NIH) | (.gov).  Evolving Patient & Provider Landscape Consumerism: Patients demand convenient, personalized care, challenging traditional models, notes Marathon Health and NEJM Catalyst Innovations in Care Delivery. New Care Models: Integration (ACOs, hospitalists) aimed at better quality/cost, but challenges in coordination persist, according to the National Institutes of Health (NIH) | (.gov). Population Health: Greater focus on prevention, chronic disease management (diabetes, obesity), and public health crises (COVID-19), says Health Data Management.  Shifting Medical Focus & Costs Precision Medicine: Tailored treatments using biomarkers are improving efficacy, notes faCellitate. Rising Costs: More expensive tech, drugs (like gene therapies), and increased demand contribute to significant spending increases, say National Institutes of Health (NIH) | (.gov) and Springer Publishing Company. Data & Billing Changes: The shift to complex coding (like ICD-10) improved data but added operational hurdles, say Becker's Hospital Review and National Institutes of Health (NIH) | (.gov) pmc.ncbi.nlm.nih.gov  .

    17 min
  7. JAN 6

    A Stem Cell Primer

    ​ This week we discuss stem cells.  Having great therapeutic and biotechnological potential, stem cells are extending the frontier in medicine. Not only replace dysfunctional or damaged cells, the so-called regenerative medicine, stem cells may also offer us new perspectives regarding the nature of aging and cancer. This review will cover some basics of stem cells, their current development, and possible applications in medicine. Meanwhile, important remaining challenges of stem cell research are discussed as well. ​Stem cells are unique, unspecialized cells that can divide to create more stem cells (self-renewal) and can transform (differentiate) into various specialized cells, acting as the body's repair system to generate new cells for growth, repair, and maintenance, with different types existing in embryos (pluripotent) and adults (multipotent) and being studied for treating diseases like paralysis, diabetes, and heart disease.   Types of Stem Cells Embryonic Stem Cells: Pluripotent (can become almost any cell type) and come from early embryos.  Adult Stem Cells (Tissue-Specific): Multipotent (limited to certain cell types within their tissue) and found in adult organs like bone marrow, skin, and the brain.  Induced Pluripotent Stem Cells (iPSCs): Adult cells reprogrammed in the lab to act like embryonic stem cells, offering a path to personalized medicine.  ​Sources of Stem Cells Embryos (for research), Umbilical cord blood, Bone marrow, Other adult tissues (like fat or skin). ​Medical Significance (Stem Cell Therapy) Regenerative Medicine: Uses stem cells to repair or replace damaged tissues and organs.  Treatments: Already used to treat blood cancers (like leukemia) through bone marrow transplants.  Research Focus: Investigated for treating conditions such as spinal cord injuries, Parkinson's, Alzheimer's, heart disease, and diabetes.  ​There is some stem cell controversy, primarily centering on the ethics of using human embryos, particularly embryonic stem cells, which hold vast potential for medicine but require destroying the embryo, raising moral debates about the embryo's status as human life, with opponents seeing it as the destruction of life and proponents viewing it as a moral imperative to cure disease, though adult stem cell research and induced pluripotent stem cells (iPSCs) offer less controversial avenues.  We don't discuss this aspect of the therapeutic use but if you are interested you can find out more with a simple internet search. ​Stem cell therapy in the US is not banned but restricted. Only FDA-approved products (such as cord blood transplants and CAR-T cell therapies for blood conditions) are fully legal. Other uses are allowed only in limited cases under the 361 HCT/P pathway.

    10 min
  8. 12/30/2025

    Functional Fitness

    This week we will discuss the topic of "functional fitness"  With the new year upon us many people want to add fitness or getting healthy as goals and we are here to help! Functional fitness is a simple, effective way to keep your body moving and reduce restlessness. It focuses on exercises that help you perform everyday activities more easily and safely—like getting up off the floor, carrying groceries, or reaching for items on a shelf. By training your muscles to work the way you actually use them in daily life, functional fitness reduces injury risk and improves overall quality of life. It helps you move through your day with more confidence, strength, and ease. Fitness expert Brad Schoenfeld describes functional fitness as existing "on a continuum." In other words, almost any exercise can be functional if it improves your ability to move well in real life. While general strength training is beneficial, exercises that mimic everyday movements tend to offer the greatest payoff. Functional fitness also improves balance, endurance, and flexibility—benefits that matter at every age. Below are 13 functional exercises suitable for adults of all ages. Choose five or six and perform them three to four times per week. All can be done safely at home with minimal equipment. 1. Squat Squats mimic sitting and standing from a chair, making them one of the most important functional movements. Move slowly and with control. To modify, reduce depth or use a chair for support. 2. Incline Chest Press This exercise strengthens the muscles used to push yourself up from the floor or a surface. It's a gentler alternative to pushups and works the same muscle groups. 3. Plank Planks build core strength, balance, and mobility—skills needed for getting up and down from the floor. Focus on maintaining good form rather than duration. 4. Wall Squat Wall squats provide added support and reduce strain on the lower back while still strengthening the legs. 5. Step-Down This movement improves balance and stability and mimics stepping down from stairs or high surfaces. 6. Row Rows strengthen the back and arms, helping with tasks like lifting objects from shelves or pulling items toward you. 7. Stationary Lunge Lunges replicate the motion of standing up from the ground and improve leg strength and joint mobility. 8. Step-Up Step-ups strengthen the muscles used for climbing stairs and stepping onto raised surfaces. 9. Single-Leg Lift Single-leg exercises improve balance and core stability, which helps prevent falls. 10. Side Plank Side planks target the oblique muscles and support overall core strength. 11. Downward-Facing Dog This yoga pose builds strength, flexibility, and balance while supporting your body weight. 12. Single-Leg Deadlift Deadlifts train the hip hinge and strengthen multiple leg muscles, preparing you for lifting objects safely. 13. Lunge with Bent-Over Row This combined movement challenges balance while strengthening both the lower and upper body. Takeaway Functional fitness prepares your body for real-life movement. It emphasizes performance over appearance, uses minimal equipment, and carries a lower risk of injury than high-intensity training styles. Because it focuses on practical strength and movement quality—not muscle size—it's accessible, effective, and appropriate for people of all ages and fitness levels. If you have existing injuries or medical conditions, consult a healthcare provider before starting.

    29 min
4.9
out of 5
28 Ratings

About

PodcastDX is an interview based weekly series. Guests share experience based medical insight for our global audience. We have found that many people are looking for a platform, a way to share their voice and the story that their health journey has created. Each one is unique since even with the same diagnosis, symptoms and the way each person will react to a diagnosis, is different. Sharing what they have experienced and overcome is a powerful way our guests can teach others with similar ailments. Many of our guests are engaging in self-advocacy while navigating a health condition, many are complex and without a road-map to guide them along their journey they have developed their own. Sharing stories may help others avoid delays in diagnosis or treatment or just give hope to others that are listening. Sharing is empowering and has a healing quality of its own. Our podcast provides tips, hints, and support for common healthcare conditions. Our guests and our listeners are just like you- navigating the complex medical world. We hope to ease some tension we all face when confronted with a new diagnosis. We encourage anyone wanting to share their story with our listeners to email us at info@PodcastDX.com ​