Passionate Pioneers with Mike Biselli

Mike Biselli

Passionate Pioneers with Mike Biselli, a nationally ranked healthcare and innovation podcast, and a member of the Health Podcast Network, highlights the innovators, the game changers, and the pioneers who are deeply passionate and relentless in valiantly solving the problems our healthcare industry is facing.

  1. Strengthening Inpatient Medicine, One Community at a Time with Dr. John Birkmeyer

    5d ago

    Strengthening Inpatient Medicine, One Community at a Time with Dr. John Birkmeyer

    This episode’s Community Champion Sponsor is Ossur. To learn more about their ‘Responsible for Tomorrow’ Sustainability Campaign, and how you can get involved: CLICK HERE Episode Overview: Physician shortages, relentless reimbursement cuts, and rising burnout are quietly destabilizing the hospitals that communities depend on most. Dr. John Birkmeyer is confronting these challenges head-on as president of Sound Physicians, a physician-founded organization partnering with more than 400 hospitals across 45 states to deliver high-quality inpatient care. A Harvard Medical School graduate and member of the National Academy of Medicine, Dr. Birkmeyer brings decades of health services research alongside executive leadership at Dartmouth Health to bear on the most pressing problems in hospital medicine today. Join us to discover how Dr. Birkmeyer and Sound Physicians are leveraging data-driven performance improvement, physician-led culture, and emerging AI tools to reduce burnout, navigate reimbursement pressures, and build a more sustainable future for inpatient care. Let's go! Episode Highlights: Dr. Birkmeyer joined Sound Physicians serendipitously, connecting through a headhunter after Dartmouth hospital partnerships fell through.Sound Physicians serves 400+ hospitals across 45 states, employing roughly 5,000 clinicians in hospital-based specialties.Medicare physician payment cuts of 7 to 8% follow six years of annual cuts, accelerating consolidation and threatening independent practices.Physician burnout stems not just from overwork, but from loss of autonomy and control over their daily practice decisions.AI will reduce documentation burden (25 to 30% of physician time) while hospital-at-home models represent Sound's next major growth frontier. About our Guest: Dr. John Birkmeyer leads the Sound medical group and is responsible for clinical affairs and performance across all specialties. A graduate of Harvard Medical School and member of the National Academy of Medicine, Dr. Birkmeyer served as Executive Vice President and Chief Academic Officer for Dartmouth Health. He is a nationally recognized health services researcher with expertise in understanding variation in hospital and provider performance, scalable strategies for quality improvement, and value-based reimbursement. Links Supporting This Episode: Sound Physicians page: CLICK HEREDr. John Birkmeyer LinkedIn page: CLICK HERESound Physicians LinkedIn page: CLICK HEREMike Biselli LinkedIn page: CLICK HEREMike Biselli Twitter page: CLICK HEREVisit our website: CLICK HERESubscribe to newsletter: CLICK HEREGuest nomination form: CLICK HERE

    30 min
  2. Leading from the Exam Room, Boardroom, and Beyond with Dr. Patrick McGill

    May 18

    Leading from the Exam Room, Boardroom, and Beyond with Dr. Patrick McGill

    This episode’s Community Champion Sponsor is Ossur. To learn more about their ‘Responsible for Tomorrow’ Sustainability Campaign, and how you can get involved: CLICK HERE Episode Overview: Healthcare in America is at a crossroads, where the systems built to heal people must now reimagine what it truly means to care for an aging and increasingly complex population. Dr. Patrick McGill, Network President and CEO of Community Health Network in Indiana, is confronting that challenge head-on. A board-certified family medicine physician with over 20 years of clinical and leadership experience, Dr. McGill has spent 15 years rising through the ranks at CHN, from practicing physician to Chief Analytics Officer to Chief Transformation Officer, and now to the top seat. Join us as Dr. McGill, who is still grounded in the exam room one day a week, shares how CHN is leading on value-based care, direct-to-employer partnerships, and AI-powered innovation to build a national-leading healthcare organization for Indiana and beyond. Let's go! Episode Highlights: Dr. McGill champions "failing intelligently," learning from mistakes and redirecting rather than fearing failure altogether.A practicing physician CEO, Dr. McGill says the exam room builds humility and credibility that no boardroom can replicate.Community Health Network sees new cancer patients within two business days, setting a bold access standard across the entire organization.Dr. McGill warns that healthcare is unprepared to support an aging population with increasingly disconnected family units.He calls on the industry to reclaim its narrative, reminding us that healthcare is still, at its core, people caring for people. About our Guest: Jason Smith is CTO of AI & Analytics at Within3, where he leads the team behind the company’s most advanced AI capabilities serving life sciences organizations. Jason is a three-time co-founder who built Cryptocybernetics, GrayArea, and rMark Bio from inception to successful exit. He was later brought in as CEO of xSides to lead its sale. Over his career, his companies have raised more than $100 million in venture and strategic capital. In addition to Within3, Jason is a Venture Fellow at MATTER, Advisor to Capita3, and a recognized thought leader in AI and Healthcare with publications and speaking engagements at HIMSS, Reuters, and leading healthcare and pharmaceutical conferences. Links Supporting This Episode: Community Health Network Website: CLICK HEREDr. Patrick McGill LinkedIn page: CLICK HEREMike Biselli LinkedIn page: CLICK HEREMike Biselli Twitter page: CLICK HEREVisit our website: CLICK HERESubscribe to newsletter: CLICK HEREGuest nomination form: CLICK HERE

    33 min
  3. Turning Data Into Confident Action: Driving AI-Powered Pharmaceutical Launch Intelligence with Jason Smith

    May 4

    Turning Data Into Confident Action: Driving AI-Powered Pharmaceutical Launch Intelligence with Jason Smith

    This episode’s Community Champion Sponsor is Ossur. To learn more about their ‘Responsible for Tomorrow’ Sustainability Campaign, and how you can get involved: CLICK HERE Episode Overview: Pharmaceutical launches are among the most complex, high-stakes endeavors in all of healthcare, and the difference between winning and losing often comes down to whether the right intelligence reaches the right people at the right moment. Jason Smith, CTO of AI and Analytics at Within3, has spent his career solving exactly that problem. A three-time co-founder whose companies have raised over $100 million in venture capital, Jason built rMark Bio from scratch before its acquisition by Within3, where his AI platform now powers launch decisions for all of the top 20 pharmaceutical companies. Join us as Jason discusses how Within3's Launch Intelligence platform unifies field insights, social signals, EHR data, and stakeholder engagement into one integrated layer, empowering pharma teams to move with clarity and confidence. Let's go! Episode Highlights: Jason sold his house, packed his dog in a U-Haul, and drove from Seattle to Chicago to launch rMark Bio in 2015.Within3 analyzes over 10 billion data points, filtered into hyper-focused disease community landscapes for pharmaceutical decision-makers.Life sciences AI differs from general models because context matters: how an MSL communicates is entirely different from a general user's query.Social listening gives pharma companies real-time aggregate patient and HCP sentiment, replacing slow, one-to-one relationship-based feedback loops.Jason is an 18-year cancer survivor and American Cancer Society advisor, making him personally invested in faster, better therapeutics for patients. About our Guest: Jason Smith is CTO of AI & Analytics at Within3, where he leads the team behind the company’s most advanced AI capabilities serving life sciences organizations. Jason is a three-time co-founder who built Cryptocybernetics, GrayArea, and rMark Bio from inception to successful exit. He was later brought in as CEO of xSides to lead its sale. Over his career, his companies have raised more than $100 million in venture and strategic capital. In addition to Within3, Jason is a Venture Fellow at MATTER, Advisor to Capita3, and a recognized thought leader in AI and Healthcare with publications and speaking engagements at HIMSS, Reuters, and leading healthcare and pharmaceutical conferences. Links Supporting This Episode: Within3 Website: CLICK HEREJason Smith LinkedIn page: CLICK HEREMike Biselli LinkedIn page: CLICK HEREMike Biselli Twitter page: CLICK HEREVisit our website: CLICK HERESubscribe to newsletter: CLICK HEREGuest nomination form: CLICK HERE

    36 min
  4. Bridging the Gap for Solo Agers: Delivering Personalized, Connected Home Care with Nicole Brackett

    Apr 20

    Bridging the Gap for Solo Agers: Delivering Personalized, Connected Home Care with Nicole Brackett

    This episode’s Community Champion Sponsor is Ossur. To learn more about their ‘Responsible for Tomorrow’ Sustainability Campaign, and how you can get involved: CLICK HERE Episode Overview: Nearly 24 million Americans over 50 now live alone — and that number is only growing. Our next guest, Nicole Brackett, is on the frontlines of solving this defining challenge as Director of Quality and Care Delivery at Homewatch CareGivers. With over 35 years of experience in long-term and dementia care, a background as a U.S. Army veteran, and nearly 22 years championing person-centered care innovation, Nicole brings a rare depth of expertise and heart to this work. From co-developing certified dementia care training to pioneering caregiver education through a cutting-edge learning management system, Nicole and the Homewatch CareGivers team are redefining what it means to age safely and independently at home. Join us as Nicole unpacks the solo aging crisis, the power of proactive care, and why independence lasts longer when assistance starts early. Let's go! Episode Highlights: Nicole Brackett brings 35+ years of healthcare experience, military service, and 22 years at HomeWatch Caregivers.Nearly 24 million Americans over 50 live alone, with 10 million solo agers projected by 2038.HomeWatch Caregivers offers "total care solutions," including technology integration and newly launched nursing services.Nicole co-developed a person-centered dementia care program focused on wellbeing, not just managing behaviors.AI-assisted caregiving and early proactive planning are key to meeting the growing solo aging crisis. About our Guest: Nicole Brackett is a dedicated healthcare professional with over 35 years of experience in long-term and Alzheimer’s/Dementia care. A veteran of Operation Desert Storm, she served eight years with the U.S. Army. Nicole is passionate about mentoring and teaching, having introduced innovative and professionally recognized assessment tools and training programs that enhance care quality and support professional development. As a Certified Eden Educator, Nicole is part of a global movement advocating for person-centered care. She is a Certified Dementia Care Educator and codeveloped Homewatch CareGivers Certified Dementia Care Training and actively contributes to the Dementia Action Alliance Organization, working to improve the lives of those living with dementia. Nicole also holds a certification in Business Acumen, aiding franchise owners and their teams in delivering exceptional care. Nicole’s leadership in bringing the Homewatch CareGivers Academy a professionally developed learning management system to her network has significantly improved caregiver training, resulting in higher quality services and better caregiver retention. Links Supporting This Episode: Homewatch Caregivers Website: CLICK HEREHomewatch Caregivers LinkedIn page: CLICK HEREMike Biselli LinkedIn page: CLICK HEREMike Biselli Twitter page: CLICK HEREVisit our website: CLICK HERESubscribe to newsletter: CLICK HEREGuest nomination form: CLICK HERE

    30 min
  5. Engineering Patient Flow Before Crises Cascade with John D'Alesandro

    Apr 6

    Engineering Patient Flow Before Crises Cascade with John D'Alesandro

    This episode’s Community Champion Sponsor is Ossur. To learn more about their ‘Responsible for Tomorrow’ Sustainability Campaign, and how you can get involved: CLICK HERE Episode Overview: Hospital operations shouldn't run on reactive chaos- they should anticipate bottlenecks before they cascade. Our next guest, John D'Alessandro, founder of Amplefi, has spent nearly two decades proving this is possible. With over 20 years transforming healthcare operations at systems like Cleveland Clinic, HCA, and Houston Methodist, John brings an unconventional background from automotive manufacturing that revolutionized his approach to patient flow. After facing his own serious diagnosis, he channeled that experience into a mission: helping frontline staff look around corners, spot smoke before fire, and reclaim control over their workday. From predicting ED admissions at triage to relieving radiology bottlenecks in hours, John shares how small signals create massive impact – without adding staff or building new space. Join us to discover why John and his team believes we must fix our systems before automating them with AI. Let's go! Episode Highlights: Hospitals are complex adaptive systems like raising children, not building cars—each facility requires unique context-based solutions dailyA simple 10-cent text alert from triage nurses predicting admissions four hours early prevents ER crashes and hallway boarding Prioritizing discharge X-rays over routine ER cases freed beds instantly, achieving 5:1 visit-to-admit ratio improvement miraculously fastAI automation accelerates broken processes, creating worse problems faster—fix management systems first before deploying expensive technology solutionsFrontline staff need protocols for "smelling smoke" early and leadership cultures that reward proactive action over reactive scrambling About our Guest: When Healthcare Operations Guru John D’Alesandro was faced with his own serious diagnosis, he was presented with a choice. To give up, or to make changes to his life and business in order to move ahead proudly. His experience in hospitals led him to his mission: to help hospital managers optimize their efforts and treat their patients more efficiently. Over 20 years of experience in hospitals, John has built a reputation for helping Directors of Bed Control and Hospital Managers. Beginning in the automotive industry with GM and Ford, focused on lean manufacturing and just-in-time supply chain lessons that became the foundation for his work in healthcare operations, working with hospital systems like the Cleveland Clinic Health System, HCA Health System, and Houston Methodist Health System. John’s approach is to engage the staff directly, upgrading their management system to fit their unique situation. to how care actually moves. He combines data analysis, process mapping, frontline coaching, and targeted use of AI to surface hidden constraints and correct the unintended consequences that drive boarding, long lengths of stay, and wasted capacity. What sets his work apart is speed: instead of multi-month improvement cycles, teams see measurable change in days. The result is improved throughput, reduced boarding, shorter LOS, and reclaimed capacity—achieved by fixing flow, not adding staff or building new space. Married for 38 years, John and his wife are proud alumni of Kettering University, parents of four daughters, and grandparents of five. Links Supporting This Episode: Amplefi Website: CLICK HEREJohn D’Alesandro LinkedIn page: CLICK HEREMike Biselli LinkedIn page: CLICK HEREMike Biselli Twitter page: CLICK HEREVisit our website: CLICK HERESubscribe to newsletter: CLICK HEREGuest nomination form: CLICK HERE

    32 min
  6. Building Prescription Price Transparency That Works Across Every Layer of Healthcare with Joseph Kleiman

    Mar 23

    Building Prescription Price Transparency That Works Across Every Layer of Healthcare with Joseph Kleiman

    This episode’s Community Champion Sponsor is Ossur. To learn more about their ‘Responsible for Tomorrow’ Sustainability Campaign, and how you can get involved: CLICK HERE Episode Overview: The prescription journey has become one of healthcare's most frustrating operational bottlenecks – fragmented pricing, disconnected systems, and zero transparency when it matters most. Our next guest, Joseph Kleiman, is transforming this broken experience as President of Buzz Health. With over 25 years building and scaling businesses, Joseph brings a rare combination of operational execution and strategic vision to one of healthcare's toughest challenges. What started 15 years ago as BuzzRx – a pharmacy discount platform – has evolved into a comprehensive pricing transparency engine embedded directly into clinical workflows. From provider systems to pharmacies to payers, Joseph shares how Buzz Health is delivering real-time cost visibility across the entire prescription ecosystem. Join us to discover how upstream pricing intelligence is reducing friction, improving adherence, and making medication affordability actionable at the point of care. Let's go! Episode Highlights: Joseph Kleiman emphasizes solving real healthcare problems by staying close to patients, pharmacies, payers, and PBMs before building solutions.Buzz Health evolved from BuzzRx discount cards to RxCompare technology, embedding real-time prescription pricing across the entire healthcare ecosystem.Successful pricing transparency requires minimal IT lift through API integrations that work alongside existing legacy systems without disruption.Moving pricing intelligence upstream to the doctor's office gives patients actionable cost information before leaving the waiting room.The future prescription ecosystem will integrate vouchers, copay cards, and health plan rates into one centralized transparent pricing engine. About our Guest: Joseph Kleiman is President of Buzz Health, where he leads the company’s strategy, partnerships, and operations to help expand access to more affordable prescription medications and improve price transparency across the healthcare ecosystem. With more than 25 years of experience building and scaling businesses, including BuzzRx as Chief Financial and Operating Officer, Kleiman has a strong track record in strategic planning, operational leadership, and growth. Previously, he founded the consulting firm Projixx, served as Chief Operating Officer of 944 Media, and co-founded Bullseye Wireless. Links Supporting This Episode: Buzz Health Website: CLICK HEREJoseph Kleiman LinkedIn page: CLICK HEREMike Biselli LinkedIn page: CLICK HEREMike Biselli Twitter page: CLICK HEREVisit our website: CLICK HERESubscribe to newsletter: CLICK HEREGuest nomination form: CLICK HERE

    28 min
  7. Unlocking Innovation Through the Science of Trust with Dr. Darryl Stickel

    Mar 9

    Unlocking Innovation Through the Science of Trust with Dr. Darryl Stickel

    This episode’s Community Champion Sponsor is Ossur. To learn more about their ‘Responsible for Tomorrow’ Sustainability Campaign, and how you can get involved: CLICK HERE Episode Overview: Trust is the foundation of every great relationship — and no one knows that better than Dr. Darryl Stickel. As Founder and CEO of Trust Unlimited, Darryl has spent over two decades transforming how leaders build deeper, more meaningful connections. Armed with a PhD from Duke University and real-world experience at McKinsey, he's earned the title "Trust Savant" for his rare ability to diagnose trust challenges and create actionable paths forward. During this episode, Darryl unpacks his practical trust-building framework, explores why vulnerability is a leadership superpower, and reveals how high-trust environments unlock innovation. Join us to discover how trust leads to hope, hope leads to choice, and choice leads to positive action. Let's go! Episode Highlights: Darryl's trust model reduces trust to perceived uncertainty times vulnerability, giving leaders a concrete, actionable framework.Leaders who model vulnerability signal safety, unlocking honest communication and enabling teams to innovate without fear of failure.In healthcare, higher trust levels lead to more accurate diagnoses, better treatment adherence, and improved patient outcomes overall.High-trust teams share information freely and embrace curiosity over judgment, creating the conditions necessary for breakthrough innovation.Darryl's Aspiring Men's Program addresses a global mental health crisis by teaching young men the relational skills trust requires. About our Guest: Darryl is one of the world’s leading experts on trust. He teaches leaders how to find and use their most powerful tool. A tool that is always in a leader’s control, how to effectively build trust in their relationships. Darryl is an unshakable force of positivity and brings the best out of people. His personal trials have strengthened his resolve and character to be a positive force for Trust. He believes in a bright future and our ability to build it together. Darryl is one of the world’s leading experts on trust. He helps high-level and executive leaders cultivate true growth and productivity in their businesses through an action-based practice of modeling vulnerability in order to improve communication and employee investment in their business. Darryl teaches leaders how to find and use their most powerful tool that is always in their control: how to effectively build trust in their relationships. Darryl is an unshakable force of positivity and brings the best out of people. His personal trials have strengthened his resolve and character to be a positive force for Trust. He believes in a bright future and our ability to build it together. Dr. Stickel is an executive coach with over 20 years of experience focused on Trust. His PhD "Building Trust in Hostile Environments" from Duke University established his unique and practical approach to Building Trust. He worked as a consultant with McKinsey & Company and has taught his methods at Universities and in Boardrooms around the world. He continues to advise and coach C-suite executives and delivers Trust workshops to small and large audiences. Described as a “Trust Savant” his ability to see clearly into trust problems, diagnose them and create a path to move forward for individuals, teams and organizations is remarkable. His Trust model is both simple and insightful. His practical experience and deep knowledge of trust make him a powerful thought partner and ally for individuals at the highest level of organizations. “I have a rare blend of deep theoretical knowledge and practical applied experience in the area of trust-building, particularly within organizational settings and across a wide range of business problems and industry sectors. Research has consistently shown that higher trust levels lead to higher levels of performance, followership and profitability.” —Darryl Stickel Links Supporting This Episode: Trust Unlimited Website: CLICK HEREDr. Darryl Stickel LinkedIn page: CLICK HEREMike Biselli LinkedIn page: CLICK HEREMike Biselli Twitter page: CLICK HEREVisit our website: CLICK HERESubscribe to newsletter: CLICK HEREGuest nomination form: CLICK HERE

    32 min
  8. Measuring Stress: The Missing Vital Sign That Triples Treatment Success with Dr. Andrew Holman

    Feb 23

    Measuring Stress: The Missing Vital Sign That Triples Treatment Success with Dr. Andrew Holman

    This episode’s Community Champion Sponsor is Ossur. To learn more about their ‘Responsible for Tomorrow’ Sustainability Campaign, and how you can get involved: CLICK HERE Episode Overview: Stress is the missing vital sign that determines whether treatments succeed or fail. Our next guest, Dr. Andrew Holman, is tackling this challenge as CEO of Inmedix. With 25 years of clinical experience as a practicing rheumatologist, Andrew possesses a unique perspective bridging medicine and diagnostics innovation. Watching billions wasted annually on autoimmune treatments that fail, he developed the CloudHRV platform to measure stress biology with medical-grade precision in just five minutes. Driven by a passion to end the trial-and-error cycle plaguing chronic disease care, Andrew shares how Inmedix tripled remission rates in rheumatoid arthritis patients from 25% to 79%. Join us to discover how stress biology is transforming precision medicine and unlocking new outcomes for the 15 million Americans living with autoimmune diseases. Let's go! Episode Highlights: FOUNDER WISDOM: Surround yourself with smarter people who tell you straight where your strengths and weaknesses are.ORIGIN STORY: A $10 million patent sale at age 46 came from championing fibromyalgia patients when they were dismissed by medicine.CLINICAL BREAKTHROUGH: The FDA-cleared CloudHRV platform tripled remission rates from 25% to 79% by measuring stress biology.FUTURE OF MEDICINE: Autonomic nervous system science may be to this century what antibiotics were to the last.PASSIONATE PIONEER MOMENT: "I try to be a learn-it-all instead of a know-it-all." About our Guest: Dr. Andrew Holman is the CEO of Inmedix. He is a practicing rheumatologist with 25 years of clinical experience who discovered the missing link in healthcare: stress—the unmeasured vital sign that determines whether treatments work or fail. As a physician watching 75% of autoimmune treatments fail while $10 billion is wasted annually on ineffective drugs, he developed Inmedix's FDA-cleared CloudHRV platform to measure stress biology with medical-grade precision in just 5 minutes. His clinical trials tripled remission rates in rheumatology from 25% to 79%, transforming medicine from trial-and-error to precision care in a $3.1 billion market. Dr. Holman brings proven commercial execution alongside clinical expertise: he leads a team with decades of experience scaling diagnostics companies through IPOs and acquisitions at Myriad Genetics, Crescendo Bioscience, and Exagen. Links Supporting This Episode: Inmedix Website: CLICK HEREDr. Andrew Holman LinkedIn page: CLICK HEREMike Biselli LinkedIn page: CLICK HEREMike Biselli Twitter page: CLICK HEREVisit our website: CLICK HERESubscribe to newsletter: CLICK HEREGuest nomination form: CLICK HEREEGuest nomination form: CLICK HERE

    31 min
5
out of 5
28 Ratings

About

Passionate Pioneers with Mike Biselli, a nationally ranked healthcare and innovation podcast, and a member of the Health Podcast Network, highlights the innovators, the game changers, and the pioneers who are deeply passionate and relentless in valiantly solving the problems our healthcare industry is facing.

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