Modern BioPharma Podcast

Jesse McLaughlin
  • 5.0 (7)
  • BUSINESS

The Modern BioPharma Podcast was born out of the 2020 COVID-19 Pandemic and the desire to connect professionals in the pharmaceutical engineering community to the stories of others around them and what they are doing to make a difference. This industry is one of resistance to change all while life altering medicines and therapies are coming into existence that demand a different kind of manufacturing plant. The same people work on these facilities across the industry. Let's get to know each other.

  1. 02/28/2023

    Season 4 - Andrew Lamore - ASME BPE

    Today's episode is with Andrew Lamore from Burkert USA Corp and ASME BPE Chair for Multi and Single-use Process Instrumentation.   As this show airs at the same time as the 30th Annual ISPE CASA Life Science Technology Showon Feb 28 2023, we thought it would be great to discuss some of the ways these two industry groups (ISPE and ASME) compliment each other to build a safer and more effective pharmaceutical manufacturing industry.  In case you were wondering...they work "hand in glove". While you certainly could have one without the other...you wouldn't want to.   Listen in. Andrew is a wonderful guest and for anyone that has met him, you know, he's just a delight to speak with.   www.asme.org/Communities/Technical/BPE  Andrew Lamore on LinkedIn ISPE CASA Annual Show 2023  Say hi to Jesse on LinkedIn www.modernbiopharma.com

    34 min

  2. 12/01/2022

    Sumit Verma of Iovance Biotherapeutics - 1 Time Therapy for Solid Tumors

    When we think about the future of medicine, we think about companies like Iovance. Iovance Biotherapeutics, Inc. is pioneering a transformational approach to treating cancer by harnessing the ability of the human immune system to recognize and attack diverse cancer cells in each patient. Their lead, late-stage TIL product candidate, lifileucel for metastatic melanoma, has the potential to become the first approved one-time cell therapy for a solid tumor cancer.   At this year's ISPE Annual Meeting in Orlando FL, I had the chance to sit down and talk about some of the things that Iovance is doing with Sumit Verma, Senior Vice President Global Strategic Manufacturing.  It was obvious to me that not only is Sumit very engaged on the "facility" level of what needs to happen to make a successful facility for our modern therapeutics, but he is passionate about the patients that Iovance is helping. This isn't just a job, its a mission.   The future of cell and gene therapy is a fascinating one, and what Sumit and his team at Iovance Biotherapeutics are doing will have monumental, life saving effects in the lives of so many where before there was little hope. Listen in our conversation! Modern Biopharma Podcast Say hi on LinkedIn

    25 min
  3. Rapid Microbiological Testing with Peggy Banarhall and Tracy Radcliffe of Mettler Toledo

    07/19/2022

    Rapid Microbiological Testing with Peggy Banarhall and Tracy Radcliffe of Mettler Toledo

    Peggy Banarhall and Tracy Radcliffe on Rapid Microbiological Testing in Pharma Waters It is hard to overemphasize the importance of water in the pharmaceutical manufacturing process. And when it comes to microbiological contamination, one of the biggest hurdles to understanding what is going on in your system is the time it takes to test. On this episode of the Modern Biopharma Podcast, I get to speak with Peggy Banarhall and Tracy Radcliffe from the Mettler Toledo team in their studio about their new technology for the rapid testing of bioburden in pharmaceutical water systems. This is a paradigm shift in understanding and dealing with bioburden. You don't need to only do a 100 year old test to figure out the health of your water system anymore. You can know what is going on RIGHT NOW...not find out in 3 days. Join us as we discuss the ins and outs of this technology and how it could help you with your system. At around the 46 minute mark we start a Demo on the unit, which may not make sense just listening to it. You can always switch over to the Youtube video at: https://youtu.be/2N5YFQYJQzQ Connect with our guests: Peggy - https://www.linkedin.com/in/peggy-banarhall-ba72412/ Tracy - https://www.linkedin.com/in/tracyradcliffe/ Jesse - https://www.linkedin.com/in/talktojesse/ Learn more about the 7000RMS at: www.mt.com Learn more about what we do at www.modernbiopharmapodcast.com Transcript Here

    1h 10m
  4. Jake Adams - CRB - The Future of ATMPs

    03/10/2022

    Jake Adams - CRB - The Future of ATMPs

    ATMPs...or Advanced Therapeutic Medicinal Products, are the "next big thing" in the world of #Pharma. If you are in the space, the big ones you hear most about are Cell & Gene Therapy and...lately...mRNA vaccines (thank you COVID-19).   This world isn't as simple as 2 or 3 therapies...it's more than that. Investment in Cell&Gene Therapy has been setting records with $20 and $23 Billion in the last 2 years alone. This is kind of a big deal.  Jake Adams, from CRB, joins me to discuss this and also the world of #RNA modulating therapies (not all as well known as mRNA Vaccines).    We discuss what makes these different therapies unique, what makes them effective, and more. Also a few rabbit trails including how did Jake turn into a go-to man for RNA as a young engineer. So listen up... :)   Check at Jake on LinkedIn!   Subscribe to our channel! Want to learn more about investment into the Cell & Gene Space? CGT 2022 Investment Outlook Learn about Oligonucleotides HERE! Quick overview about TPDs HERE!

    56 min
  5. Jon Browne - Qualification & Commissioning in Pharma

    03/01/2022

    Jon Browne - Qualification & Commissioning in Pharma

    If you are anywhere around the commissioning and qualification space, you know how important it is to any #Pharmaceutical facility. There are so many resources out there to understanding how to approach these processes and on today’s episode of the Modern Biopharma Podcast I spoke with Jon Brown about his experience coming into a new facility and how he approached the substantial task of managing the commissioning of one of the largest Water For Injection (#WFI) systems in the world. Jon is a graduate of the University of Utah and currently works as a consultant in the RTP area serving pharmaceutical manufacturers there. I really enjoyed getting to know Jon through our conversations Questions we cover in the podcast: Tell me a little about yourself and what you currently do. 2:05 - What is a book that you’ve recently read that you especially enjoyed? Algorithms to Live By (already started it and really enjoying it) 6:00 - Today we’re going to talk about commissioning and qualification of water systems…tell me more about why you enjoy working on water systems 8:00 What was your “task” and how did you approach CQ differently for this project? 15:00 - What do you care about in your quality system? 26:00 - How do we determine system boundaries? 36:30 - How important is it to both define those boundaries and DEFEND those boundaries from a quality perspective? 49:40 - What’s the number #1 thing you’d encourage a CQV team to do as they embark on a new system? As some follow-up reading, here is a great article about Good Engineering Practices in Risk-Based Commissioning and Qualification by Chip Bennett. https://ispe.org/pharmaceutical-engineering/may-june-2020/good-engineering-practice-risk-based-commissioning

    53 min
  6. AI-ML in Pharma Manufacturing - Vijay Yadav - Merck

    02/22/2022

    AI-ML in Pharma Manufacturing - Vijay Yadav - Merck

    When you think of Artificial Intelligence, you may think of some scene from a movie where robots are taking over the world…well, I can’t say that won’t happen :), but I can say, that some people are starting to find ways to make manufacturing medicine more efficient using it. On today’s episode of the Modern Biopharma Podcast, I had the pleasure of talking with Vijay Yadav, from Merck. We didn’t talk about robots taking over the world, but we did talk about how Vijay’s team is leading the industry and finding new ways to make AI and Machine Learning useful towards a more efficient and higher quality future in the modern biopharmaceutical plant. While many are talking about it, Vijay and his team are doing it. Listen in…today we talk about: AI vs ML – Explain the difference The Automated Vision Inspection process What made this process a success? What were the risks/downsides of running this technology? What makes the culture different that you’ve been able to make such progress with AI in an industry that is so resistant to change? How have you been able to build a team for this work? It seems that other industries are driving this kind of work Learn more about Vijay through one of his articles: https://ispe.org/pharmaceutical-engineering/november-december-2020/vision-inspection-using-machine https://towardsdatascience.com/quantify-the-business-impact-of-your-data-science-project-b742e4b3208f https://www.linkedin.com/pulse/artificial-intelligence-vs-machine-learning-whats-what-vijay-yadav-1/

    44 min
  7. Blockchain in Pharma - Tanya Sharma and Najib Rehman

    12/16/2021

    Blockchain in Pharma - Tanya Sharma and Najib Rehman

    In today's emerging BioPharma space, the importance of transparent and accurate records related to therapies, how they are made, where they are in a process, and the patient they are for has never been more important. A need this large should not be relying on technology from 30 years ago. The Pharma 4.0 world has a lot of components...One way of helping the Pharma Industry catch up with the technologies they are creating is by utilizing Blockchain.  On today's episode, Najib Rehman from ATMPS and Tanya Sharma from Assurea, join me to talk about how Blockchain can be used to help our industry make a JUMP towards more available therapies for more people.     Here are some things we discuss today:   Explain Blockchain to me like I'm a 10 year old.   Who owns blockchain? It has a reputation for being very secure...why is that?   Why are you advocating for using blockchain in the Pharma Industry? Are there particular areas within the industry that blockchain is best suited for?   Is there a certain level of adoption needed to make this "work" or is the infrastructure already in place?   How does blockchain impact 21 CFR Compliance?    What downsides are there to instituting blockchain?   How does using blockchain as a tool in Pharma help to serve the patient?   Some other items that we touch on are:  Need for competitor cooperation  Paper versus digital  Digital disintermediation of supply chains  Personalized medicine - patient centric   How do you "manage forever"?   Tanya Sharma - https://www.linkedin.com/in/tsharma2/  Naj Rehman - https://www.linkedin.com/in/najib-rehman-54011412/  Jesse McLaughlin - https://www.linkedin.com/in/talktojesse/  Modern BioPharma Podcast - https://www.linkedin.com/company/modern-biopharma-podcast

    54 min

  8. 11/17/2021

    The Pharma Job Market - An Interview Mashup

    It is a RED HOT Job Market (at least right now it is in 2021)...and the Pharma market is leading the pack.  On this episode of the Modern BioPharma Podcast, I interviewed 3 different organizations to talk about what the Pharma Job Market looks like right now, how it has changed due to COVID, ways to stick out in a crowded marketplace, and more...!!!   Our Guests today include:   Jonathan Hart-Smith from the CK Group, a staffing and outsourcing services for the science and technology community.   Bill Burg (https://www.linkedin.com/in/bill-burg-22651531/) and Kyle Reagan (https://www.linkedin.com/in/kyle-w-reagan-2218731/) from DECCO Inc., a mechanical contracting company that specializes in construction, maintenance, and fabrication services to leading biopharmaceutical, technology and industrial clients throughout New England.   Shawn Fitzpatrick and Charlie Maher from Resilience, a pharmaceutical organization that is changing the way medicine is made – leveraging innovation to better serve scientific discovery, withstand disruptive events, and reach those in need.   Listen in as we see the job market from different angles...  Where are the biggest needs?  What has changed since COVID changed our world?  How to best position yourself for a position?  How are companies changing how THEY approach the talent pool?  How are companies developing talent as early as high school to serve in jobs that we just don't have people for?   I hope you enjoy this episode. As always, reach out if you have any suggestions for future episodes by connecting with me on LinkedIn at https://www.linkedin.com/in/talktojesse/ or at www.modernbiopharma.com.

    46 min
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About

The Modern BioPharma Podcast was born out of the 2020 COVID-19 Pandemic and the desire to connect professionals in the pharmaceutical engineering community to the stories of others around them and what they are doing to make a difference. This industry is one of resistance to change all while life altering medicines and therapies are coming into existence that demand a different kind of manufacturing plant. The same people work on these facilities across the industry. Let's get to know each other.

Information

  • Creator
    Jesse McLaughlin
  • Years Active
    2020 - 2023
  • Episodes
    33
  • Rating
    Clean
  • Copyright
    © Jesse McLaughlin
  • Show Website
    Modern BioPharma Podcast