The Tech Humanist Show

Kate O'Neill

where data and technology meet humanity

  1. FEB 26

    Upgrading Human Vision with Professor Daniel Palanker

    What happens when technology doesn’t just restore light sensitivity, but actually brings back the ability to perceive forms, patterns, and meaning for those who’ve lost their sight? Dive into this episode as we explore how breakthroughs in retinal prostheses are reshaping human experience. Topics covered: The difference between light sensitivity and form vision How the Prima retinal prosthesis works Wireless design and integration with natural vision Selective stimulation and preserving retinal code Challenges in encoding vision and lessons from animal to human trials Patient perspectives and life impact Upgrading implants and future breakthroughs Comparing biological and electronic restoration approaches The meaning of vision for identity, independence, and connection The hope and future of vision restoration worldwide Connect with Professor Daniel PalankerStanford MedicineLinkedIn Episode Chapters: 00:05 Introduction to The Tech Humanist Show 00:17 Surprises in clinical trials and complexity of vision 00:41 The impact of vision and restoration 01:14 Episode arc and Professor Palanker’s breakthrough 02:02 Welcoming Professor Daniel Palanker 02:10 Prima system restores form vision 02:55 Distinct lived experience between light sensitivity and form vision 03:10 Examples of restored capability and simultaneous vision 04:49 How Prima works at the chip-glasses-human interface 05:01 Disease background: Age-related macular degeneration 07:01 External augmented reality glasses explained 08:21 Why Prima is wireless 10:13 Implant design and surgical simplicity 11:21 Preserving peripheral vision and the “don’t fix what’s not broken” philosophy 12:53 Selective retinal stimulation and proper encoding 14:37 Vision processing features and their importance 17:54 Brain’s interpretation of signals and meaning 19:22 Challenges of encoding further from the source 21:58 Journey: Concept to clinical implementation 26:17 Impact for patients—stories and real-world uses 28:03 Resolution, experience, and what higher resolution unlocks 31:20 Testing new indications and upgradable implants 32:32 Biological vs. electronic approaches and collaboration 35:13 Philosophical meaning of vision for identity and connection 37:26 Hope for the future of vision restoration 40:06 Market future and product evolution 40:39 Episode wrap-up and gratitude

    41 min
  2. FEB 19

    What It Means To See – Insights from Dr. Lauren Ayton

    What does it truly mean to see—and how close are we to restoring sight for those who have lost it? Dr. Lauren Ayton shares her journey at the frontier of vision restoration, from leading Australia’s first bionic eye trial to navigating the ethical, scientific, and personal dimensions of bringing sight back. Topics covered: The meaning of “seeing” and how the brain constructs vision Personal motivations behind vision restoration research The evolution of bionic eyes and retinal implants From basic science to technological intervention in vision Ethical dilemmas in emerging vision restoration technologies Patient experiences regaining sight and decision-making in trials Challenges of public perception vs. scientific reality Incremental innovation vs. paradigm shifts in medical science Importance of access, equity, and foundational care Designing technology for real human needs and capabilities Connect with Dr. Lauren AytonLinkedInCentre for Eye Research Australia Episode Chapters:00:00 – Introduction: What does it mean to see?01:45 – Dr. Lauren Ayton’s personal journey and driving questions03:35 – Career: Academia, startup life, and innovation in vision science05:27 – The complexity and subjectivity of vision07:08 – What happens when vision is restored? Patient experiences08:52 – Scientific breakthroughs that made sight restoration imaginable10:37 – The science behind bionic eyes, retinal implants, and gene therapy12:30 – Suprachoroidal approach in Australia’s first in-human bionic eye trial13:59 – Ethics of risk, hope, and consent in experimental medicine15:56 – Supporting patients through uncertainty and high-stakes decisions17:26 – Managing expectations: Public perception vs. current scientific reality20:08 – Incremental change, paradigm shifts, and multidisciplinary collaboration22:00 – Translation: From brilliant ideas to real-world impact24:06 – Access, equity, and the bigger picture of vision care25:48 – Human-driven innovation: Designing for dignity, capability, and real needs27:30 – Lessons from vision science about clarity, perception, and what we miss28:52 – The future: What’s possible in 10–20 years of vision restoration30:19 – Ethical reminders for the path ahead31:44 – Dr. Lauren Ayton’s takeaways: Centering humans and aiming high32:57 – How to support or get involved in vision research33:45 – What’s keeping Dr. Lauren Ayton hopeful34:46 – Closing and credits

    35 min
  3. FEB 12

    Restoring Sight – Dr. José-Alain Sahel’s Innovations in Vision and Human Flourishing

    What does it truly mean to see—and how can technology restore one of our most essential human senses? In this episode, Dr. José-Alain Sahel joins Kate O’Neill to reveal the breakthroughs in vision restoration, and how these innovations are shaping the future of human experience. Topics Covered: Optogenetic therapy and vision restoration Artificial retina technology Scientific and patient journey of regaining sight Convergence of AI, neuroscience, and medical devices Philosophy of sight and perception Natural vs. artificial boundaries in biotech Balancing innovation and patient safety Strategies for treating different stages of blindness Meaning and legacy of vision technologies Connect with: Dr. José-Alain SahelThe Eye & Ear Foundation of PittsburghUPMC Enterprises Episode Chapters: 00:00:05 – Welcome to the Tech Humanist Show 00:01:14 – Introduction of Dr. José-Alain Sahel 00:02:29 – 2021 Optogenetic Vision Restoration Breakthrough 00:02:46 – Recent Artificial Retina Breakthrough (2025) 00:03:47 – The First Patient’s Experience 00:06:31 – Explaining the Technology: Algae Proteins & Retinal Cells 00:09:00 – Scientific Process: Failures, Persistence, and Progress 00:10:13 – How the Goggles Work 00:11:03 – Training the Brain to Interpret New Visual Input 00:11:24 – The Patient’s Story: From Blindness to Seeing Again 00:16:07 – Philosophical Perspective on Sight and Perception 00:20:02 – Measuring Human Experience in Vision Restoration 00:23:26 – Natural vs. Artificial: Ethics and Human Augmentation 00:26:19 – Balancing Innovation with Patient Safety in Clinical Trials 00:29:53 – Complementary Strategies for Blindness Treatment 00:31:34 – Vision, Meaning, and Human Flourishing 00:34:41 – Where to Find More About Dr. Sahel’s Work 00:35:49 – Episode Credits & Outro

    37 min
  4. FEB 5

    The Future of Work is Grey with Dan Pontefract

    What if the real future-of-work crisis isn’t about technology replacing humans—but organizations pushing out workers just when their wisdom is needed most? In this episode, Kate O’Neill and Dan Pontefract explore the urgency of rethinking age in the workplace, longevity, and designing meaningful work for six-decade careers. Topics covered: Age and longevity in the workforce Fluid vs. crystallized intelligence The demographic “age debt” challenge AI and human intelligence collaboration Multidirectional, time-flexible careers Rethinking succession planning and wisdom transfer Designing learning ecosystems Evolution of purpose throughout a career Concrete steps leaders can take to turn age debt into dividends Connect with Dan PontefractWebsiteLinkedInYouTubeInstagramTikTokDan’s new book – “The Future is Grey” Episode Chapters:00:05 Welcome and Introduction00:36 The Real Crisis: Age and Work02:01 Dan’s Wake-Up Call: Fired at 5003:39 Longevity vs Organizational Blind Spots06:10 Lessons from Japan: The Age Canary07:14 Chief Longevity Officers: Action or Gray Washing?09:42 Fluid & Crystallized Intelligence in the Age of AI14:10 Rivers, Rocks, and Rubies: Beyond Generational Stereotypes18:09 Building Multi-Directional Careers22:00 “Gray” Means Embracing the In-Between22:44 Succession Planning vs Wisdom Transfer26:46 Learning Ecosystems for All Ages30:06 How Purpose Evolves Over Time33:01 3 Steps for Leaders: Actionable Guidance37:11 How to Use Rivers, Rocks, & Rubies in Practice39:11 Dan’s Personal “Gray” Future42:01 What’s Next for Dan and Final Thoughts43:26 Closing and Where to Connect

    44 min
  5. JAN 29

    Soft Skills, Hard Truths with Dr. Bushra Khan

    What if the “soft skills” we often overlook are actually the most strategic—and essential—in the age of AI? In this episode, leadership expert Dr. Bushra Khan and host Kate O’Neill explore the power and business impact of emotional intelligence, challenging outdated leadership myths and redefining what skills matter most for future-ready teams. Topics Covered: Why “soft skills” should be called “strategic skills” Emotional intelligence as a leadership framework Evidence-based emotional intelligence in organizations Critical thinking, persuasion, and influence for tech leaders Challenging the myth of micromanagement Culture’s impact on leadership assumptions Candor vs. bluntness in high-stakes communication Balancing bravery and kindness in decision making Practical approaches to EI skill-building in companies Finding hope and optimism in leadership Connect with: Dr. Bushra KhanLinkedinWebsite Episode Chapters: 00:00:05 – Welcome & redefining soft skills 00:00:37 – Emotional intelligence as leadership 00:01:20 – Reframing skills for a tech-driven world 00:01:55 – Why “soft” is inadequate and damaging 00:02:49 – Strategic skills vs. technical expertise 00:04:33 – Critical thinking & real-life practice 00:05:43 – Evidence-based EI: Research & impact 00:06:05 – Describing great leaders (EI in action) 00:08:47 – EQ vs. IQ & technical skills 00:11:06 – The emotional intelligence framework 00:12:34 – Making EI accessible in everyday life 00:13:24 – The myth of micromanagement 00:15:46 – Coaching, mentoring, and trust 00:17:13 – Cross-context skills: work, life, community 00:17:43 – Leadership mental models across cultures 00:18:35 – Cultural differences in trust and hierarchy 00:22:23 – Candor, clarity, and high-stakes communication 00:23:14 – Building trust for high-pressure moments 00:26:33 – Balancing bravery and kindness 00:29:29 – EI is not just being nice—using frameworks 00:31:34 – Practical “how” for applying EI 00:32:07 – Why companies should invest in human skills 00:32:41 – Making skills training bite-sized and evidence-based 00:35:44 – Key takeaways & actionable advice 00:36:23 – Finding hope and optimism in leadership 00:39:53 – Gratitude and closing remarks

    41 min
  6. JAN 22

    Asking Better Questions with Ben Pring

    What are the questions only humans can ask in an age where AI seems to have all the answers? In this episode, Kate O’Neill and futurist Ben Pring dive deep into the uniquely human skills and judgments that technology can’t replicate, and explore how leaders and organizations can navigate uncertainty, ask better questions, and shape a more human-centered future. Topics covered:Placing today’s AI advancements in historical context How technology replaces skill with judgment The value of asking better questions in an AI-driven world Why leaders avoid tough decisions about humans vs. machines How incentives and alignment shape organizational outcomes The policy gaps at the intersection of technology, strategy, and labor Distinguishing human creativity from AI-generated “slop” How to maintain humanity and funkiness in a synthetic content flood Hope and optimism for the future of work and technology Connect with Ben Pring: benpring.com Episode Chapters:00:00:05 – Welcome to the Tech Humanist Show 00:00:18 – The Human Ability to Ask the Next Best Question 00:00:32 – Computers Are Useless: Asking the Right Questions 00:01:05 – Introducing Ben Pring 00:02:21 – Historical Context for Today’s AI Moment 00:04:47 – Technology: Replacing Skill with Judgment 00:08:14 – What Leaders Should Be Asking in an AI-Powered World 00:13:08 – Why Leaders Avoid Tough Questions About Automation 00:16:13 – Decision-Making in Times of Uncertainty 00:19:10 – Distinguishing Priorities from Trivialities 00:24:22 – Aligning Incentives and Unintended Consequences 00:25:41 – Have We Gotten Better at Taming the Monster? 00:29:26 – The Most Important Policy Questions We’re Not Asking 00:33:59 – The Car as a Parallel: Infrastructure and Human-Centric Design 00:36:21 – What Remains Distinctly Human in a Synthetic Content World 00:41:01 – Invention, Funkiness, and Problem-Solving 00:42:46 – Hope and Optimism for the Future 00:49:03 – Closing and Where to Find Ben Pring

    50 min
  7. JAN 15

    Rethinking Climate Action with Tom Chi

    What if climate action and economic growth aren’t at odds—but actually deeply aligned? In this episode, Kate O’Neill sits down with Tom Chi to challenge conventional thinking about climate solutions, innovation, and the future of planetary restoration. Topics Covered: The emotional impact of witnessing coral reef collapse Reimagining climate action through the lens of both ecology and economy Lessons from Google X: rapid prototyping and low-cost innovation How Google Glass shaped the understanding of visual information and human experience Insights into planetary restoration and urgent timelines for action The concept of “Climate Capital” and investment strategies for sustainability Aligning ecological wins with economic incentives Overcoming barriers in climate-tech: capex inertia and effective policy Interconnectedness and its influence on business and technology Innovative approaches for sustainable material management Connect with Tom Chi:LinkedInAt One Ventures Website Episode Chapters: 00:00:05 – Welcome & Introduction to the Tech Humanist Show 00:00:15 – Tom Chi on Reef Collapse and Global Tragedy 00:00:43 – Rethinking Climate Action: Ecology vs. Economy 00:02:15 – Conversation Kickoff: Meet Tom Chi 00:02:36 – Google X, Rapid Prototyping, and Hardware Innovation 00:06:24 – Augmenting Human Vision: Google Glass Discoveries 00:13:08 – From Tech Innovator to Planetary Restoration 00:16:33 – The Gravity of Coral Loss & Civilization-Scale Decisions 00:19:47 – Becoming Net Positive to Nature: NE Ventures Approach 00:21:01 – What “Climate Capital” Really Means 00:27:01 – Structuring Climate-Tech Investments & Timelines 00:28:57 – Advice for Funders: Overcoming Green Premiums 00:33:15 – Interconnectedness: Tech, Nature, and Business 00:38:43 – Building Lasting Systems with Nature 00:39:13 – The One Law to Accelerate Climate Solutions 00:47:21 – Empowering Change: Rates Not States 00:47:30 – Book Release: Climate Capital 00:48:17 – Closing Remarks & How to Connect

    49 min
  8. JAN 8

    Bas Warmerdam on Thinking Like a Child for Professionals on Organizational Challenges

    What if the secret to solving your organization’s toughest problems was thinking like a 10-year-old? Discover how childlike creativity and fun can reframe complex business challenges, spark innovation, and drive real results. Topics Covered: Childlike thinking for organizational problem-solvingPlayful penalties to boost accountabilityStorytelling and translating complex issues for kidsChange management through unbiased perspectivesDementia care and deepfake technology solutionsMechanisms for creativity: no rules, have fun, do good, no shameDesigning inclusive, impactful brainstorming sessionsBridging playfulness and business gravitasApplying kid-inspired thinking to AI and executive decisionsKeeping curiosity and creative practice alive in organizations Connect with Bas Warmerdam:ConsultingKids.comLinkedIn Episode Chapters00:00:05 – Welcome & Intro to the Tech Humanist Show00:00:17 – “Playful Penalties” concept and team accountability00:00:41 – Bas Warmerdam’s work with Consulting Kids00:01:50 – Approach and methodology using children as junior consultants00:03:38 – Reframing collaboration problems through childlike solutions00:04:24 – Implementing playful penalties and organizational impact00:06:02 – The “Thinking Like a Child for Professionals” process00:08:27 – Bringing executives into the classroom and change management benefits00:09:23 – Storytelling for complex issue translation00:12:14 – Mechanisms for leaders to use childlike thinking in their teams00:15:09 – Four key thinking mechanisms from kids00:15:50 – Example: Dementia care and “no rules” thinking00:18:28 – How professionals can integrate fun and purpose00:19:55 – Embracing “no shame” in creative business solutions00:20:41 – Creating inclusion for quiet and underrepresented voices00:22:03 – Reintegration: Bringing creative ideas into business practice00:24:21 – Childlike thinking for AI-related decisions00:26:55 – Using kid-driven creativity to challenge AI authority00:28:40 – Sustaining childlike thinking post-consulting00:30:41 – Keeping curiosity sharp and connecting at home00:32:19 – How to connect with Bas Warmerdam and Consulting Kids00:32:55 – Closing remarks and credits

    34 min

Trailer

5
out of 5
6 Ratings

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where data and technology meet humanity