The MicrobiomeResearchX (MRX) Podcast

Adarsh Sandhu
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  • LIFE SCIENCES

The MRX Podcast offers the latest research highlights, news, and trends for the global community of scientists focused on uncovering the functions of the microbiome for human health.

  1. 10/01/2025

    Mohammad Arifuzzaman： Finalist 2025 NOSTER & Science Microbiome Prize

    Today’s guest is Mohammad Arifuzzaman from the Department of Medicine, Weill Cornell Medicine, Cornell University, and one of the 2025 Prize Winners of the NOSTER & Science Microbiome Prize. His essay, “Illuminating Microbial Dark Matter,” reveals how changes in diet can bring to light previously unknown molecules made by gut microbes. These hidden microbial products act like messengers, quietly influencing our immunity and metabolism in ways we are only beginning to understand. Mohammad’s work shows how uncovering these signals could lead to precision nutrition and entirely new therapeutic strategies. Mohammad Arifuzzaman Illuminating microbial dark matter: Dietary alterations uncover microbial regulation of immunity and metabolism. Science 389,38-38(2025). DOI:10.1126/science.adz0502

    14 min

  2. 10/01/2025

    Ayele Argaw-Denboba： Finalist 2025 NOSTER & Science Microbiome Prize

    Today’s guest is Ayele Argaw-Denboba from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg, Germany, and one of the 2025 Prize Winners of the NOSTER & Science Microbiome Prize. is essay, “The gut microbiome–germline axis,” shows that disturbances in a father’s gut microbes can alter sperm and pass on health risks to the next generation — but restoring the microbiome can reverse these effects. Ayele Argaw-Denboba The gut microbiome–germline axis: Does a prospective father’s gut microbiota matter? Science 389,38-38 (2025). DOI:10.1126/science.adz0492

    9 min

  3. 10/01/2025

    Djenet Bousbaine：Grand Prize Winner of the 2025 NOSTER & Science Microbiome Prize

    Today’s guest is Djenet Bousbaine from Stanford University, the 2025 Grand Prize winner of the NOSTER & Science Microbiome Prize. Her essay, “Skin microbiota: the vaccine we were already wearing,” shows how the microbes living on our skin quietly train our immune system. And now, by working with these microbes, her team is pointing us towards the possibility of safe, needle-free vaccines. Djenet Bousbaine  The vaccine we all wear: Skin microbiota can be engineered into topical vaccines. Science 389, 37-38 (2025). DOI:10.1126/science.adz0485

    12 min

  4. 12/13/2024

    Brittany Needham: Finalist of the 2024 NOSTER & Science Microbiome Prize

    Our guest today is Brittany Needham at Indiana University who is a finalist of the 2024 NOSTER & Science Microbiome Prize for his essay entitled " Exposed wires: A microbial metabolite influences myelination in the brain.”   Details about the prize-winning essay www.science.org/doi/10.1126/science.adq2344 Brittany Needham  Exposed wires: A microbial metabolite influences myelination in the brain.  Science 385,37-37(2024).  DOI:10.1126/science.adq2344

    11 min

  5. 12/13/2024

    Lina Yao：Finalist 2024 2024 NOSTER & Science Microbiome Prize

    Our guest today is Lina Yao at Harvard Medical School who is a finalist of the 2024 NOSTER & Science Microbiome Prize for his essay entitled " Breaking boundaries: Bacteria act as architects of host T cell modulators using bile acids.”   Details about the prize-winning essay www.science.org/doi/10.1126/science.adq2341 Lina Yao  Breaking boundaries: Bacteria act as architects of host T cell modulators using bile acids. Science385,37-37(2024). DOI:10.1126/science.adq2341

    17 min

  6. 12/13/2024

    Kazuki Nagashima: Grand Prize winner of the 2024 NOSTER & Science Microbiome Prize

    Our guest today is Kazuki Nagashima at Stanford University, who is the grand prize winner of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "Blockbuster T cells in the gut: A high-resolution view of immune modulation by the gut microbiome is presented.”   Details about the prize-winning essay www.science.org/doi/10.1126/science.adq2335 Kazuki Nagashima Blockbuster T cells in the gut: A high-resolution view of immune modulation by the gut microbiome is presented.  Science385,36-37(2024). DOI:10.1126/science.adq2335

    12 min

  7. 09/27/2023

    Christoph A. Thaiss: Finalist of the 2023 NOSTER & Science Microbiome Prize

    Our guest today is Christoph A. Thaiss the Microbiology Department of the Perelman School of Medicine at the University of Pennsylvania, who is a finalist of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "A microbiome exercise: gut-brain connections drive the motivation to work out.”   Details about the prize-winning essay https://www.science.org/doi/10.1126/science.adi6329 Essay: A microbiome exercise Science, 381, 6653, p. 38, 2023.  DOI: 10.1126/science.adi6329 Related research  L. Dohnalová et al A microbiome-dependent gut-brain pathway regulates motivation for exercise.  Nature, 612(7941):739-747, 2022.  DOI: 10.1038/s41586-022-05525-z. E

    20 min

  8. 09/27/2023

    Christopher Stewart: Finalist of the 2023 NOSTER & Science Microbiome Prize

    Our guest today is Christopher Stewart of the Translational and Clinical Research Institute at Newcastle University, who is a finalist of the 2023 NOSTER & Science Microbiome Prize for his essay entitled "Diet-microbe-host interaction in early life: breastmilk bioactives are important to infant microbiome.”   Details about the prize-winning essay https://www.science.org/doi/10.1126/science.adi6318 Essay: Diet-microbe-host interaction in early life Science, 381, 6653, p. 38, (2023) DOI: 10.1126/science.adi6318 Related research  C. J Stewart et al, Temporal development of the gut microbiome in early childhood from the TEDDY study.  Nature 562 (7728): 583-588, (2018).  DOI: 10.1038/s41586-018-0617-x.

    13 min
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The MRX Podcast offers the latest research highlights, news, and trends for the global community of scientists focused on uncovering the functions of the microbiome for human health.

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