Solving the Puzzle with Dr. Datis Kharrazian

Datis Kharrazian, PhD, DHSc, DC, MS, MMSc, FACN
  • 4.9 (99)
  • Health & Fitness
  • Updated Weekly

Solving the Puzzle with Dr. Datis Kharrazian is based on more than 20 years of Dr. Kharrazian's experience working with autoimmune and brain health patients throughout the U.S. and Europe, exhaustive review of the scientific research, and protocols he has innovated through trial and error in working with complex patient cases. Dr. Kharrazian discusses evidence-based models incorporating diet, nutrition, and lifestyle — protocols hard won through decades of working with tough, complex patient cases.  His goal is to help teach you effective models for so-called “mystery” symptoms and conditions so you can regain control of your health and life. Hashimoto's: Solving the Puzzle, is a new online course from Dr. Kharrazian, who is the originator of evidence-based strategies for managing autoimmune Hashimoto's hypothyroidism. This course has the most complete and current information for managing Hashimoto's available. You can find more information at drknews.com. Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

  1. 3d ago

    Episode 96: Diet, Sleep & Circadian Rhythm for Fatigue Syndromes

    In this episode we dive into the metabolic and lifestyle foundations that drive chronic fatigue, ME/CFS, and energy dysfunction. Blood sugar stabilization is covered in depth, from managing hypoglycemia and insulin resistance to the role of ketogenic nutrition in difficult cases that have not responded to other approaches. We also look at hydration and electrolyte balance as an underappreciated piece of cellular energy production, and walk through practical sleep strategies including weighted blankets, white noise, mouth taping, and building a consistent sleep routine.  Register for Chronic Fatigue and Pain Syndromes Clinical Strategies and Treatment Applications at https://pages.kharrazianinstitute.com/chronic-fatigue-and-pain-syndromes To become a Certified Functional Medicine practitioner, visit https://kharrazianinstitute.com/⁠. Try our 7-day free trial, no credit card required.  TIMESTAMPS:  00:00 Discussing blood sugar and energy levels 06:17 Ketogenic diet benefits for ME/CFS 10:16 Getting started with intermittent fasting 12:01 Intermittent fasting and autophagy benefits 15:40 Hydration and fatigue management tips 18:58 Addressing sleep hygiene basics 23:14 Benefits of weighted blankets and calming aids 27:14 Improving sleep for chronic fatigue 30:00 Promoting educational health resources Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

  2. Jul 15

    Episode 95: The Truth About Hormone Replacement Therapy for Cardiovascular and Cognitive Health

    In this episode, Randy Vawdrey dives into the world of hormone optimization, challenging decades of conventional wisdom that has stigmatized hormone therapy, especially for women. You'll hear an evidence-based exploration into the role hormones like DHEA, estrogen, progesterone, and testosterone play in cardiovascular prevention, brain health, and longevity. We’ll unpack landmark studies, expose misconceptions rooted in outdated research, and share powerful stories and expert interviews that reveal how proper hormone management can transform lives. Enroll in the Master Class: Preventive Cardiology: Comprehensive & Integrative CV Risk Reduction with Randy Vawdrey, NP-C at https://pages.kharrazianinstitute.com/vawdrey-cardio TIMESTAMPS:  00:00 Understanding DHEA and DHEA-S 04:04 DHEA and cardiovascular health 08:05 DHEA's role in heart disease 12:24 Using DHEA for better health 14:31 Discussing hormone treatments 16:14 The impact of 2001 study 21:39 Debunking hormone replacement myths 25:19 FDA's stance on hormone therapy 27:03 Doctor's views on hormone therapy 30:21 Prescribing BHRT to older patients 35:13 Closing remarks and resources Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

  3. Jul 7

    Episode 94: The Truth About Cholesterol, CAC Scores, and Heart Attack Risk

    In today’s episode, Randy Vawdrey dives into cardiovascular prevention with a special focus on coronary artery calcium (CAC) testing. He guides us through why traditional cardiovascular risk factors like LDL cholesterol, HDL, and BMI may not be as predictive of heart attack risk as once thought, and how CAC scores can provide a much clearer picture. You'll hear about the latest research, practical steps for interpreting CAC scores, and the lifestyle and supplemental interventions that can help halt the progression of cardiovascular disease.  Enroll in the Master Class: Preventive Cardiology: Comprehensive & Integrative CV Risk Reduction with Randy Vawdrey, NP-C at https://pages.kharrazianinstitute.com/vawdrey-cardio TIMESTAMPS:  00:00 Discussing cardiac risk assessment factors 05:50 Predictive value of CAC scores 07:17 Understanding Agatston scores 10:22 Boulder cardiologist's health tips 13:52 Discussing methylfolic acid and statins 16:42 Managing stress with coronary scores 20:17 Podcast sponsor shout-out and disclaimers Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

  4. Jul 2

    Episode 93: Optimizing Omega 3 Levels for Brain and Heart Health

    Today, we’re diving into the world of Omega 3 fatty acids with Randy Vawdrey, NP-C. He unpacks why they are so critical for brain and cardiovascular health, how dietary patterns and supplement choices can make or break your Omega 3 levels, and what the latest research tells us about optimal dosing and safety. Whether you're a clinician, health professional, or simply looking to optimize your own well-being, this episode will help you understand the science behind fatty acid ratios, how to properly interpret lab values, and the importance of choosing the right kind of supplementation.  Enroll in the Master Class: Preventive Cardiology: Comprehensive & Integrative CV Risk Reduction with Randy Vawdrey, NP-C at https://pages.kharrazianinstitute.com/vawdrey-cardio 00:00 Omega 3s and cell membranes 05:37 Rise of Seed Oils in America 07:54 Omega 6:3 ratio in veterans 12:10 Understanding omega-3 sources and protocol 16:20 Omega 3 absorption discussion 17:14 Discussing Omega 3 dosage recommendations 22:03 Discussing Omega 3 supplements 23:34 Promoting online courses and resources Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

  5. Jun 23

    Episode 92: Understanding Chronic Pain and Fatigue

    Today, we’re diving into the enigma of chronic pain and fatigue. Dr. Kharrazian unpacks the science and physiology behind pain, revealing that it’s not simply a sensory experience but an intricate interaction between our nerves, brain, and even our emotions. From explanations of hyperalgesia and allodynia to the crucial role the limbic system and amygdala play in amplifying or diminishing our experience of pain, this episode bridges the gap between what’s happening beneath the surface and practical strategies for those suffering from ongoing discomfort. Register for Chronic Fatigue and Pain Syndromes Clinical Strategies and Treatment Applications at https://pages.kharrazianinstitute.com/chronic-fatigue-and-pain-syndromes To become a Certified Functional Medicine practitioner, visit https://kharrazianinstitute.com/⁠. Try our 7-day free trial, no credit card required.  00:00 Understanding pain and sensitization 04:19 Understanding brain-based pain signals 08:28 Understanding referred pain mechanisms 12:02 Triggers and amplification of pain 15:07 Explaining gait control theory 17:07 How the sympathetic system works 22:08 Understanding central pain syndromes 25:06 Closing and listener resources Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

  6. Jun 16

    Episode 91: Managing Musculoskeletal Symptoms in Menopause

    In this episode, Leslie Fuller, ND focused on the often-overlooked musculoskeletal symptoms experienced by women during perimenopause and menopause. She discusses strategies for effective management, including nutrition, resistance training, hormone assessment, and addressing both structural and functional health. This episode offers healthcare professionals and patients evidence-based approaches to support musculoskeletal health through the menopausall transition. Enroll now in: Under-Recognized, Under-Treated, and Misrepresented Realities of the Perimenopause and Menopause Transition, with Leslie Fuller, ND and Jillian Moehle, ND at https://pages.kharrazianinstitute.com/fuller-moehle-perimenopause 00:00 Menopause-related musculoskeletal issues 06:32 Assessing musculoskeletal conditions 10:25 Identifying osteoporosis risk factors 13:48 Comprehensive management for inflammation repair 15:07 Discussing menopause and bone health 18:48 Future FDA approval and nutrition strategies 24:30 Effects of Isoflavones and Lignans 25:40 Calcium and vitamin D benefits 31:14 Creatine and CoQ10 for muscle health 33:42 Importance of aerobic and resistance training 38:13 Combating sarcopenia through referrals 39:17 Screening for menopausal musculoskeletal syndrome Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

  7. Jun 9

    Episode 90: GSM Essentials for 2025: Top Treatment Updates, Safety Guidance, and Patient Impact

    In this episode, Jillian Moehle focused on the latest evidence-based strategies for recognizing and treating Genitourinary Syndrome of Menopause (GSM). She explored newly updated guidelines from the American Urological Association, emphasizing the importance of proactive screening, a comprehensive approach to patient history, and the range of therapeutic options available, from non-hormonal treatments like moisturizers and lubricants, to hormone-based therapies including low-dose vaginal estrogen. Several points were raised, including safety considerations, the removal of the FDA black box warning on vaginal estrogen, and the crucial role of pelvic floor health in patient outcomes. Enroll now in: Under-Recognized, Under-Treated, and Misrepresented Realities of the Perimenopause and Menopause Transition, with Leslie Fuller, ND and Jillian Moehle, ND at https://pages.kharrazianinstitute.com/fuller-moehle-perimenopause 00:00 Vaginal treatment recommendations and concerns 05:26 Discussing hormone therapy alternatives 08:13 Treatment options for vaginal health 13:16 FDA removes black box warning 15:24 Support for vaginal estrogen use 18:13 Using GoodRx and applying cream 22:00 Possible side effects and management 24:54 Impact of GSM on women's health 30:59 Podcast outro and resources sharing Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

  8. Jun 2

    Episode 89: Why Millions of Women Were Failed by the Women’s Health Initiative Study

    In this episode, we’re diving into the complex and often misunderstood topic of menopause and perimenopause. Despite affecting every woman who lives into late life, menopause has long been underfunded, understudied, and minimized both culturally and medically. Today, we’ll explore why clinical care for women in the menopause transition has lagged behind, examining the deep historical roots of gender bias in research, the fragmentation of women's healthcare, and the profound impact of the Women’s Health Initiative (WHI) study, which triggered decades of fear and misinformation about hormone therapy.  Enroll now in: Under-Recognized, Under-Treated, and Misrepresented Realities of the Perimenopause and Menopause Transition, with Leslie Fuller, ND and Jillian Moehle, ND at https://pages.kharrazianinstitute.com/fuller-moehle-perimenopause 00:00 Historical oversight in menopause care 06:00 Women's Health Initiative study flaws 08:29 Impact of WHI study miscalculation 10:28 Misinterpretation of breast cancer risks 13:44 Correcting hormone therapy myths 17:23 Podcast resources and educational courses Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

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About

Solving the Puzzle with Dr. Datis Kharrazian is based on more than 20 years of Dr. Kharrazian's experience working with autoimmune and brain health patients throughout the U.S. and Europe, exhaustive review of the scientific research, and protocols he has innovated through trial and error in working with complex patient cases. Dr. Kharrazian discusses evidence-based models incorporating diet, nutrition, and lifestyle — protocols hard won through decades of working with tough, complex patient cases.  His goal is to help teach you effective models for so-called “mystery” symptoms and conditions so you can regain control of your health and life. Hashimoto's: Solving the Puzzle, is a new online course from Dr. Kharrazian, who is the originator of evidence-based strategies for managing autoimmune Hashimoto's hypothyroidism. This course has the most complete and current information for managing Hashimoto's available. You can find more information at drknews.com. Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

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