Conversations with CEI

Clinical Education Initiative

Conversations with Clinical Education Initiative (CEI) features clinical experts in HIV Primary Care and Prevention, Sexual Health, Hepatitis C and Drug User Health. Our episodes feature CEI clinicians’ experience and insight on the current health issues, alongside the latest news and guidelines on our areas of expertise. This podcast is produced by the CEI, a New York State Department of Health AIDS Institute program.

  1. 2D AGO

    What “The 72-Hour Rule” Update Means for New York State

    Effective February 19, 2026, New York State law permits clinicians to dispense up to 72 hours (equivalent to a 3-day supply) of controlled substances, such as methadone and buprenorphine, for the management of opioid withdrawal while arranging referral and linkage to care for persons with opioid use disorder, as authorized by federal regulations (specifically, the Code of Federal Regulations or CFR number 1306.07). The federal regulations were updated in August 2023, and New York State law is just now catching up. We informally refer to the update as “The 72-Hour Rule.” Featuring Dr. Linda Wang, this episode reviews what this update means for New York State and how clinicians and healthcare administrators can think about its implementation. Are you implementing “The 72-Hour Rule” in clinical practice in New York State? We want to hear from you! Please reach out to share your experience: Lauren.walker3@mountsinai.org. Related Content:  New York State Senate Bill S3416D: https://www.nysenate.gov/legislation/bills/2025/S3416/amendment/D Code of Federal Regulations (CFR) § 1306.07: https://www.ecfr.gov/current/title-21/chapter-II/part-1306/subject-group-ECFR1eb5bb3a23fddd0/section-1306.07 Skogrand E, et al. (2024). Dispensing methadone at hospital discharge: One hospital’s approach to implementing the “72-hour rule” change. J Addict Med. 2024; 18(1):71-74. doi: 10.1097/ADM.0000000000001246. Shahlapour M, et al. (2024). Novel uses of methadone under the “72-hour rule” to facilitate transitions of care and low-dose buprenorphine induction in an outpatient bridge clinic. J Addict Med. 2024; 18(3):345-347. doi: 10/1097/ADM.0000000000001281. Taylor JL, et al. (2022). Bridge clinic implementation of "72-hour rule" methadone for opioid withdrawal management: Impact on opioid treatment program linkage and retention in care. Drug Alcohol Depend. 2022; 236:109497. doi: 10.1016/j.drugalcdep.2022.109497. CEI Clinical Consultation Line 1-866-637-2342 A toll-free service for NYS clinicians offering real-time clinical consultations with specialists on HIV, sexual health, hepatitis C, and drug user health. https://ceitraining.org/

    20 min
  2. JAN 12

    Two New Treatments for Gonorrhea; one is available now!

    In this episode of the Conversations with CEI, infectious disease specialist Dr. Steven Fine delves into groundbreaking advancements in the treatment of urogenital gonorrhea. The episode highlights the FDA's December 2025 approval of two innovative oral therapies that mark a significant step forward in combating this prevalent sexually transmitted infection. Dr. Fine discusses the first of these treatments, Zoliflodacin (Nuzolvence), a novel medication specifically developed for urogenital gonorrhea. Administered as a single oral dose, it offers patients a convenient and effective option. The second treatment, Gepotidacin (Blujepa), is a versatile drug initially approved in March 2025 for urinary tract infections (UTIs). Now, it has been authorized for urogenital gonorrhea treatment, requiring two oral doses for optimal efficacy. Throughout the episode, Dr. Fine provides insights into the clinical trials, mechanisms of action, and potential impact of these therapies on public health. He also emphasizes the importance of addressing antibiotic resistance in gonorrhea and how these new treatments may help mitigate this growing concern. For more information, listeners can refer to the FDA's official announcement and other resources provided below. Tune in to this episode to learn more about these exciting developments and their implications for the future of infectious disease treatment. Related Content:  FDA Approves Two Oral Therapies to Treat Gonorrhea https://www.fda.gov/news-events/press-announcements/fda-approves-two-oral-therapies-treat- gonorrhea CEI Clinical Consultation Line 1-866-637-2342 A toll-free service for NYS clinicians offering real-time clinical consultations with specialists on HIV, sexual health, hepatitis C, and drug user health. https://ceitraining.org/

    15 min
  3. 11/20/2025

    PrEParing for Lenacapavir Implementation in Your Clinic: Early Lessons Learned

    On June 18, 2025, the FDA approved Yeztugo, the brand name for subcutaneous lenacapavir, a prescription medication used for the pre-exposure prophylaxis of HIV.  Subcutaneous lenacapavir is administered twice a year (every six months) to reduce the risk of sexually acquired HIV-1 infection in adults and adolescents at risk. With patients only needing lenacapavir twice a year for HIV prevention, the field has been optimistic about the potential for lenacapavir to reduce barriers and improve access to PrEP. Since we are still early in the rollout subcutaneous lenacapavir, many providers have questions about how to offer it to their patients—from workflow to billing to managing potential side effects and drug-drug interactions. On this episode, Antonio Urbina, MD, Medical Director for CEI’s HIV Primary Care and Prevention Center of Excellence, speaks with Alex Danforth, PharmD. Alex Danforth is a clinical pharmacist in Rochester, NY.  She practices at Trillium Health, a federally qualified health center, where she works with patients and providers to help manage medications and optimize care.  Alex currently provides clinical leadership for HIV treatment and prevention programs.  Drs. Urbina and Danforth talk about the latest New York State Clinical Guidelines for PrEP, which were updated on October 16th. The new guidelines provide important updates, including subcutaneous lenacapavir. They discuss important considerations for initiating patients on lenacapavir as well as some early lessons learned from implementing lenacapavir in their Rochester- and New York City-based clinics. Related Content:  PrEP to Prevent HIV and Promote Sexual Health University of Liverpool HIV Drug Interactions Checker (website and app) CEI Line: 1-866-637-2342 https://ceitraining.org/

    28 min
  4. 10/09/2025

    Recap of the 2025 Annual New York State Hepatitis C and Drug User Health Conference

    On September 9th, CEI hosted its first in-person conference dedicated to hepatitis C and drug user health. A group of New York State-based clinicians met in Catskill for a full day agenda focused on (1) integrating wellness into clinical practice as a way to improve patient care and outcomes, and (2) innovative decision-making frameworks to help clinicians navigate complex scenarios in the absence of strong formal evidence, like clinical guidelines and peer reviewed studies. This episode of “Conversations with CEI” features conference planner and facilitator Taylor Edelmann – an educator and consultant working at the intersection of LGBTQIA+ health, drug user health and harm reduction – sharing his experience and insights about the day. Taylor currently oversees the Lighthouse Learning Collective at the National Harm Reduction Coalition, a program focused on supporting LGBTQIA+ harm reductionists and people who use drugs and engage in sex work. As one of the first openly transgender NCAA athletes, Taylor brings a deeply personal lens to his work advocating for gender-affirming care. He regularly provides clinical education and technical assistance to providers across the country, including Yale University and one of Connecticut’s largest federally qualified health centers, and recently presented at the 2025 Harm Reduction International Conference in Bogotá, Colombia. Taylor is also the co-creator of ChemSex Awareness Week, and the lead author of Gender Affirming Harm Reduction: A Toolkit for Syringe Service Programs, the first resource of its kind developed specifically for social service providers in harm reduction settings.  Related Content:  2025 Annual NYS Hepatitis C and Drug User Health conference website: https://ceitraining.org/conference/conferences/3 Lighthouse Learning Collective at the National Harm Reduction Coalition: https://harmreduction.org/our-work/action/lighthouse-learning-collective/ Gender Affirming Harm Reduction: A Toolkit for Syringe Service Programs: https://lighthousetoolkit.my.canva.site/ Narrative Medicine: https://www.aamc.org/news/narrative-medicine-every-patient-has-story Drug, Set, and Setting: The Basis for Controlled Intoxicant Use: https://southwestrecoveryalliance.org/wp-content/uploads/2020/02/Drug-Set-and-Setting-Zinberg-N-1.pdf CEI Clinical Consultation Line 1-866-637-2342 A toll-free service for NYS clinicians offering real-time clinical consultations with specialists on HIV, sexual health, hepatitis C, and drug user health. ceitraining.org

    27 min
  5. 07/10/2025

    Highlights and Perspectives from the 11th Annual NYS Sexual Health Conference

    Live from Canandaigua…it’s the 11th Annual NYS Sexual Health Conference! The CEI Sexual Health Center of Excellence hosted the 11th Annual NYS Sexual Health Conference in-person on Friday May 2, 2025, in beautiful Canandaigua, NY. This was the Center’s second in-person conference since the COVID-19 pandemic and was the Center’s largest in-person event held to-date, bringing together over 225 clinicians and public health professionals from across NYS (and beyond!).  In this episode, host Juhua Wu, Director of the University of Rochester Center for Community Practice and team member of the CEI Sexual Health Center of Excellence, checks in live from the conference with four presenters about their experience at the conference, perspectives on what they learned from other sessions, and “need to know” highlights from their own presentations. Join Juhua, along with Rachel Hart-Malloy, PhD, MPH, Brenda Tesini, MD, Michael Brennan, DNP, FNP, and Jeremy Kidd, MD, MPH, for a real-time review of the conference! Related Content: STI Dashboard New York: https://www.stidashboardny.org/   Chemsex: Questions and Answers: https://www.suguidelinesnys.org/guideline/chemsex/  New York State Department of Health, Healthy Sex campaign: https://campaigns.health.ny.gov/SexualHealth  University of Rochester Center for Community Practice: www.urccp.org  CEI Clinical Consultation Line 1-866-637-2342 A toll-free service for NYS clinicians offering real-time clinical consultations with specialists on HIV, sexual health, hepatitis C, and drug user health. ceitraining.org

    17 min

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About

Conversations with Clinical Education Initiative (CEI) features clinical experts in HIV Primary Care and Prevention, Sexual Health, Hepatitis C and Drug User Health. Our episodes feature CEI clinicians’ experience and insight on the current health issues, alongside the latest news and guidelines on our areas of expertise. This podcast is produced by the CEI, a New York State Department of Health AIDS Institute program.